ES2197811A1 - Synthesis of beta lactamic antibiotic fluorescent derivatives consists of molecularly imprinted polymer administration increasing animal origin food antibiotics identification - Google Patents

Synthesis of beta lactamic antibiotic fluorescent derivatives consists of molecularly imprinted polymer administration increasing animal origin food antibiotics identification

Info

Publication number
ES2197811A1
ES2197811A1 ES200200794A ES200200794A ES2197811A1 ES 2197811 A1 ES2197811 A1 ES 2197811A1 ES 200200794 A ES200200794 A ES 200200794A ES 200200794 A ES200200794 A ES 200200794A ES 2197811 A1 ES2197811 A1 ES 2197811A1
Authority
ES
Spain
Prior art keywords
beta
synthesis
animal origin
identification
imprinted polymer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES200200794A
Other languages
Spanish (es)
Other versions
ES2197811B2 (en
Inventor
Moraleda Guillermo Orellana
Lara Santiago Aparicio
Bondi Maria Cruz Moreno
Pena Elena Benito
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Universidad Complutense de Madrid
Original Assignee
Universidad Complutense de Madrid
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Universidad Complutense de Madrid filed Critical Universidad Complutense de Madrid
Priority to ES200200794A priority Critical patent/ES2197811B2/en
Publication of ES2197811A1 publication Critical patent/ES2197811A1/en
Application granted granted Critical
Publication of ES2197811B2 publication Critical patent/ES2197811B2/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
    • C09K11/00—Luminescent, e.g. electroluminescent, chemiluminescent materials
    • C09K11/06—Luminescent, e.g. electroluminescent, chemiluminescent materials containing organic luminescent materials
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Materials Engineering (AREA)
  • Biophysics (AREA)
  • Optics & Photonics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The synthesis of beta-lactomic antibiotic fluorescent derivatives comprises production of sensitive agents for rapid qualitative and quantitative detection of antibiotics in e.g. foods of animal origin. The technique can include the use of molecularly imprinted polymer.
ES200200794A 2002-04-05 2002-04-05 SYNTHESIS OF FLUORESCENT DERIVATIVES OF BETA-LACTAMIC ANTIOBIOTICS. Expired - Fee Related ES2197811B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
ES200200794A ES2197811B2 (en) 2002-04-05 2002-04-05 SYNTHESIS OF FLUORESCENT DERIVATIVES OF BETA-LACTAMIC ANTIOBIOTICS.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES200200794A ES2197811B2 (en) 2002-04-05 2002-04-05 SYNTHESIS OF FLUORESCENT DERIVATIVES OF BETA-LACTAMIC ANTIOBIOTICS.

Publications (2)

Publication Number Publication Date
ES2197811A1 true ES2197811A1 (en) 2004-01-01
ES2197811B2 ES2197811B2 (en) 2005-05-01

Family

ID=30470537

Family Applications (1)

Application Number Title Priority Date Filing Date
ES200200794A Expired - Fee Related ES2197811B2 (en) 2002-04-05 2002-04-05 SYNTHESIS OF FLUORESCENT DERIVATIVES OF BETA-LACTAMIC ANTIOBIOTICS.

Country Status (1)

Country Link
ES (1) ES2197811B2 (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101402706B (en) * 2008-11-13 2010-06-09 上海交通大学 Method for preparing tsiklomitsin molecular engram polymer used for water environment
WO2021094410A1 (en) * 2019-11-15 2021-05-20 F. Hoffmann-La Roche Ag Derivatization of beta-lactam antibiotics as calibrators/istd in massspec measurements

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5741657A (en) * 1995-03-20 1998-04-21 The Regents Of The University Of California Fluorogenic substrates for β-lactamase and methods of use

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5741657A (en) * 1995-03-20 1998-04-21 The Regents Of The University Of California Fluorogenic substrates for β-lactamase and methods of use

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
CARTWRIGHT, S.J. & FINK, A.L. Isolation of a covalent intermediate in beta-lactamase I catalysis. FEBS Letters. Enero 1982, Vol. 137, Nº 2, paginas 186-188. *
MUNNS, R.K. et al. Multiresidue method for determination of eight neutral beta-lactam Penicillins in milk by Fluorescence- Liquid Chromatography. J. Assoc. Off. Anal. Chem., 1985, Vol. 68, Nº 5, paginas 968-971. *
ZHAO, G. et al. BOCILLIN FL, a sensitive and commercially available reagent for detection of Penicillin-Binding Proteins. Antimicrobial Agents and Chemotherapy. Mayo 1999, Vol. 43, Nº 5, paginas 1124-1128. *
ZLOKARNIK, G. et al. Emerging fluorescence sensing technologies: From photophysical principles to cellular applications. Proc. Natl. Acad. Sci. USA. Julio 1999, Vol. 96, paginas 8336-8337. *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101402706B (en) * 2008-11-13 2010-06-09 上海交通大学 Method for preparing tsiklomitsin molecular engram polymer used for water environment
WO2021094410A1 (en) * 2019-11-15 2021-05-20 F. Hoffmann-La Roche Ag Derivatization of beta-lactam antibiotics as calibrators/istd in massspec measurements

Also Published As

Publication number Publication date
ES2197811B2 (en) 2005-05-01

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