ES2196853T3 - Procedimiento para la obtencion de formas de dosificacion solidas. - Google Patents

Procedimiento para la obtencion de formas de dosificacion solidas.

Info

Publication number
ES2196853T3
ES2196853T3 ES99946047T ES99946047T ES2196853T3 ES 2196853 T3 ES2196853 T3 ES 2196853T3 ES 99946047 T ES99946047 T ES 99946047T ES 99946047 T ES99946047 T ES 99946047T ES 2196853 T3 ES2196853 T3 ES 2196853T3
Authority
ES
Spain
Prior art keywords
dosage forms
solid dosage
agent
procedure
obtaining solid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES99946047T
Other languages
English (en)
Inventor
Reinhard Spengler
Jorg Rosenberg
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott GmbH and Co KG
Original Assignee
Abbott GmbH and Co KG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott GmbH and Co KG filed Critical Abbott GmbH and Co KG
Application granted granted Critical
Publication of ES2196853T3 publication Critical patent/ES2196853T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2893—Tablet coating processes

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Laminated Bodies (AREA)
  • Application Of Or Painting With Fluid Materials (AREA)

Abstract

Procedimiento para la obtención de formas de dosificación sólidas mediante formación de una mezcla plástica constituida por un 10 a un 99, 9 % en peso de al menos un agente aglutinante polímero, un 0, 1 a un 90 % en peso de al menos un producto activo, y en caso dado aditivos habituales, y conformado con la mezcla plástica exenta de disolvente para dar las formas de dosificación sólidas por medio de una herramienta de moldeo, caracterizado porque, en el conformado, se aplica un agente modificador de propiedades superficiales en forma finamente distribuidas sobre la superficie de la mezcla plástica en una cantidad tal que el agente modificador de propiedades superficiales en la forma de dosificación sólida obtenida constituye un 0, 01 a un 1, 0 % en peso, referido al peso total de la forma de dosificación sólida, aplicándose el agente modificador de propiedades superficiales en primer lugar en forma finamente distribuidas sobre las superficies de las herramientas de moldeo, que entran en contacto con la mezcla plástica a moldear, y después de cada contacto de las superficies de la herramienta de moldeo con la mezcla plástica se efectúa una nueva aplicación de agente modificador de propiedades superficiales.
ES99946047T 1998-08-28 1999-08-27 Procedimiento para la obtencion de formas de dosificacion solidas. Expired - Lifetime ES2196853T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19839276A DE19839276A1 (de) 1998-08-28 1998-08-28 Verfahren zur Herstellung von festen Dosierungsformen

Publications (1)

Publication Number Publication Date
ES2196853T3 true ES2196853T3 (es) 2003-12-16

Family

ID=7879077

Family Applications (1)

Application Number Title Priority Date Filing Date
ES99946047T Expired - Lifetime ES2196853T3 (es) 1998-08-28 1999-08-27 Procedimiento para la obtencion de formas de dosificacion solidas.

Country Status (9)

Country Link
US (1) US6669879B1 (es)
EP (1) EP1107739B1 (es)
JP (1) JP2002523185A (es)
CN (1) CN1170525C (es)
AT (1) ATE235896T1 (es)
CA (1) CA2341646C (es)
DE (2) DE19839276A1 (es)
ES (1) ES2196853T3 (es)
WO (1) WO2000012068A1 (es)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2359945C (en) 1999-11-12 2011-04-26 Abbott Laboratories Inhibitors of crystallization in a solid dispersion
US7364752B1 (en) 1999-11-12 2008-04-29 Abbott Laboratories Solid dispersion pharamaceutical formulations
DE10026698A1 (de) 2000-05-30 2001-12-06 Basf Ag Selbstemulgierende Wirkstoffformulierung und Verwendung dieser Formulierung
GB0113841D0 (en) * 2001-06-07 2001-08-01 Boots Co Plc Therapeutic agents
US8025899B2 (en) 2003-08-28 2011-09-27 Abbott Laboratories Solid pharmaceutical dosage form
US8377952B2 (en) 2003-08-28 2013-02-19 Abbott Laboratories Solid pharmaceutical dosage formulation
US7927616B2 (en) * 2004-01-16 2011-04-19 Thomas T. Yamashita Pesticide compositions and methods for their use
WO2005115343A2 (de) * 2004-05-28 2005-12-08 Abbott Gmbh & Co. Kg Dosierungsform, erhältlich aus einer ein anorganisches pigment umfassenden pulvermischung
WO2006045152A1 (en) * 2004-10-29 2006-05-04 Mayne Pharma International Pty Ltd Improved tabletting process
PT1674399E (pt) * 2004-12-22 2007-02-28 M & P Patent Ag Utilização de um recipiente feito de um material plástico contendo um aditivo inorgânico
US20060140820A1 (en) 2004-12-28 2006-06-29 Udo Mattern Use of a container of an inorganic additive containing plastic material
US8404275B2 (en) 2007-07-01 2013-03-26 Vitalis Llc Combination tablet with chewable outer layer
WO2009132208A1 (en) * 2008-04-24 2009-10-29 Evestra, Inc. Oral contraceptive dosage forms comprising a progestogen dispersed in an enteric polymer and further comprising an estrogen
DE102011010437A1 (de) * 2011-02-04 2012-08-09 J. Rettenmaier & Söhne Gmbh + Co. Kg Tablettierhilfsmittel
US9757388B2 (en) 2011-05-13 2017-09-12 Acerus Pharmaceuticals Srl Intranasal methods of treating women for anorgasmia with 0.6% and 0.72% testosterone gels
AR086400A1 (es) 2011-05-13 2013-12-11 Trimel Pharmaceuticals Corp Formulaciones en gel intranasal de testosterona en dosis de menor potencia y uso de las mismas para el tratamiento de la anorgasmia o el trastorno de deseo sexual hipoactivo
US20130045958A1 (en) 2011-05-13 2013-02-21 Trimel Pharmaceuticals Corporation Intranasal 0.15% and 0.24% testosterone gel formulations and use thereof for treating anorgasmia or hypoactive sexual desire disorder
US9226891B2 (en) 2011-10-28 2016-01-05 Vitalis Llc Anti-flush compositions
CN102697660B (zh) * 2012-06-04 2014-02-12 贵州景峰注射剂有限公司 一种去除微丸丸间静电的方法
US11744838B2 (en) 2013-03-15 2023-09-05 Acerus Biopharma Inc. Methods of treating hypogonadism with transnasal testosterone bio-adhesive gel formulations in male with allergic rhinitis, and methods for preventing an allergic rhinitis event
US9375033B2 (en) 2014-02-14 2016-06-28 R.J. Reynolds Tobacco Company Tobacco-containing gel composition
US20170182070A1 (en) 2014-10-08 2017-06-29 Mayne Pharma International Pty Ltd. Controlled Release Doxycycline

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3612211A1 (de) 1986-04-11 1987-10-15 Basf Ag Kontinuierliches verfahren zum tablettieren
WO1993007859A1 (en) 1991-10-23 1993-04-29 Warner-Lambert Company Novel pharmaceutical pellets and process for their production
JPH06218028A (ja) 1992-10-02 1994-08-09 Eisai Co Ltd 湿製錠の成型方法とその装置及び湿製錠
DE4446468A1 (de) 1994-12-23 1996-06-27 Basf Ag Verfahren zur Herstellung von umhüllten Tabletten
DE4446467A1 (de) * 1994-12-23 1996-06-27 Basf Ag Verfahren zur Herstellung von linsenförmigen Tabletten durch Schmelzkalandrierung
DE19710213A1 (de) * 1997-03-12 1998-09-17 Basf Ag Verfahren zur Herstellung von festen Kombinationsarzneiformen

Also Published As

Publication number Publication date
JP2002523185A (ja) 2002-07-30
EP1107739B1 (de) 2003-04-02
CA2341646C (en) 2008-10-21
CA2341646A1 (en) 2000-03-09
ATE235896T1 (de) 2003-04-15
CN1325298A (zh) 2001-12-05
EP1107739A1 (de) 2001-06-20
DE19839276A1 (de) 2000-03-02
DE59904868D1 (de) 2003-05-08
US6669879B1 (en) 2003-12-30
CN1170525C (zh) 2004-10-13
WO2000012068A1 (de) 2000-03-09

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