ES2188816T3 - Procedimiento para preparar 4,6-hihidroxipirimidina. - Google Patents

Procedimiento para preparar 4,6-hihidroxipirimidina.

Info

Publication number
ES2188816T3
ES2188816T3 ES97107402T ES97107402T ES2188816T3 ES 2188816 T3 ES2188816 T3 ES 2188816T3 ES 97107402 T ES97107402 T ES 97107402T ES 97107402 T ES97107402 T ES 97107402T ES 2188816 T3 ES2188816 T3 ES 2188816T3
Authority
ES
Spain
Prior art keywords
formamide
hydroxypyrimidine
prepare
procedure
alkoxide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES97107402T
Other languages
English (en)
Other versions
ES2188816T5 (es
Inventor
Artur Hunds
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Evonik Operations GmbH
Original Assignee
Degussa GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26027158&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2188816(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from DE19640756A external-priority patent/DE19640756B4/de
Application filed by Degussa GmbH filed Critical Degussa GmbH
Application granted granted Critical
Publication of ES2188816T3 publication Critical patent/ES2188816T3/es
Publication of ES2188816T5 publication Critical patent/ES2188816T5/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/52—Two oxygen atoms
    • C07D239/54—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

LA INVENCION TRATA DE UN PROCEDIMIENTO PARA LA PRODUCCION DE 4,6 FORMAMIDA Y UN ALCOHOLATO DE METAL ALCALINO A UNA TEMPERATURA ELEVADA. AL RESPECTO, EL ESTER MALONICO PUEDE SER AÑADIDO EN PORCIONES O CONTINUAMENTE, POR SEPARADO O JUNTO CON LA CANTIDAD TOTAL O UNA CANTIDAD PARCIAL DE LA FORMAMIDA, AL ALCOHOLATO DE METAL ALCALINO QUE SE PRESENTA COMO SOLUCION O SUSPENSION, POR SEPARADO O JUNTO CON LA CANTIDAD TOTAL O LA CANTIDAD PARCIAL RESIDUAL DE LA FORMAMIDA, EN UN ALCOHOL.
ES97107402T 1996-07-03 1997-05-05 Procedimiento para preparar 4,6-dihidroxipirimidina. Expired - Lifetime ES2188816T5 (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE19626747 1996-07-03
DE19626747 1996-07-03
DE19640756A DE19640756B4 (de) 1996-07-03 1996-10-02 Verfahren zur Herstellung von 4,6-Dihydroxypyrimidin
DE19640756 1996-10-02

Publications (2)

Publication Number Publication Date
ES2188816T3 true ES2188816T3 (es) 2003-07-01
ES2188816T5 ES2188816T5 (es) 2006-06-01

Family

ID=26027158

Family Applications (1)

Application Number Title Priority Date Filing Date
ES97107402T Expired - Lifetime ES2188816T5 (es) 1996-07-03 1997-05-05 Procedimiento para preparar 4,6-dihidroxipirimidina.

Country Status (6)

Country Link
US (1) US5847139A (es)
EP (1) EP0816345B2 (es)
JP (1) JPH1067755A (es)
CN (1) CN1175576A (es)
AT (1) ATE231843T1 (es)
ES (1) ES2188816T5 (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9610320D0 (en) * 1996-05-17 1996-07-24 Zeneca Ltd Chemical process
KR100676222B1 (ko) * 1999-08-18 2007-01-30 바이엘 악티엔게젤샤프트 4,6-디클로로-5-플루오로피리미딘의 제조방법
DE10140269A1 (de) * 2001-08-16 2003-02-27 Degussa Verfahren zur Herstellung von 4,6-Dihydroxypyrimidin
CN102442954B (zh) * 2011-09-06 2014-01-08 淄博万昌科技股份有限公司 利用丙烯腈副产氢氰酸制备4，6-二羟基嘧啶的方法
CN113227058A (zh) * 2018-12-28 2021-08-06 赛拓有限责任公司 用于制备4,6-二羟基嘧啶的改进方法
CN112979561B (zh) * 2021-04-29 2021-09-03 潍坊滨海石油化工有限公司 一种合成4,6-二羟基嘧啶的后处理方法
CN113444050B (zh) * 2021-08-30 2021-11-19 潍坊滨海石油化工有限公司 一种4,6-二羟基嘧啶的生产方法
CN114605336B (zh) * 2022-04-06 2024-01-26 荆州三才堂化工科技有限公司 一种合成4,6-二羟基嘧啶的后处理及其废水资源化利用的方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1200308B (de) * 1961-08-17 1965-09-09 Dresden Arzneimittel Verfahren zur Herstellung von 4, 6-Dihydroxy-pyrimidinen
US3306900A (en) * 1964-02-21 1967-02-28 Kyowa Hakko Kogyo Kk Method for producing 4,6-dihydroxy-pyrimidine
CN1082031A (zh) † 1993-05-20 1994-02-16 郑州市孝义制药厂 磺胺间甲氧嘧啶的制备方法
GB9610320D0 (en) † 1996-05-17 1996-07-24 Zeneca Ltd Chemical process

Also Published As

Publication number Publication date
EP0816345A1 (de) 1998-01-07
CN1175576A (zh) 1998-03-11
US5847139A (en) 1998-12-08
EP0816345B1 (de) 2003-01-29
ES2188816T5 (es) 2006-06-01
EP0816345B2 (de) 2006-01-18
ATE231843T1 (de) 2003-02-15
JPH1067755A (ja) 1998-03-10

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