ES2186799T3 - Bencimidazoles sustituidos en 5' utilizados como agentes antivirales. - Google Patents
Bencimidazoles sustituidos en 5' utilizados como agentes antivirales.Info
- Publication number
- ES2186799T3 ES2186799T3 ES96928176T ES96928176T ES2186799T3 ES 2186799 T3 ES2186799 T3 ES 2186799T3 ES 96928176 T ES96928176 T ES 96928176T ES 96928176 T ES96928176 T ES 96928176T ES 2186799 T3 ES2186799 T3 ES 2186799T3
- Authority
- ES
- Spain
- Prior art keywords
- bencimidazols
- sub
- replaced
- antiviral agents
- polisustituted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000003443 antiviral agent Substances 0.000 title 1
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical group [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical group 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/052—Imidazole radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- Communicable Diseases (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Virology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
LA PRESENTE INVENCION SE REFIERE A BENCIMIDAZOLES POLISUSTITUIDOS QUE TIENEN LA FORMULA (I), EN LA QUE Q ES UN GRUPO BENCIMIDAZOL SUSTITUIDO UNIDO A LA POSICION 1 DE BENCIMIDAZOL, R ES UN HALOGENO O UN NUMERO ATOMICO DE 9 A 53, INCLUSIVE, (A SABER, R SUB,1}, DONDE X ES UN CALCOGENO DE NUMERO ATOMICO DE 8 A 16, INCLUSIVE, (A SABER, LO DE CADENA LINEAL O RAMIFICADA DE 1 A 8 ATOMOS DE CARBONO; Y R SUB,2} Y R SUB,3} PUEDEN SER IGUALES O DIFERENTES Y SON POR SEPARADO BER, ES OPERATIVAS DE LOS MISMOS. TAMBIEN SE PRESENTAN EN ESTA INVENCION COMPOSICIONES QUE CONTIENE BENCIMIDAZOLES POLISUSTITUIDOS COMO LOS ARRIBA DEFINIDOS Y METODOS PARA EL USO DE LOS MISMOS.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US254295P | 1995-08-18 | 1995-08-18 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2186799T3 true ES2186799T3 (es) | 2003-05-16 |
Family
ID=21701262
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES96928176T Expired - Lifetime ES2186799T3 (es) | 1995-08-18 | 1996-08-16 | Bencimidazoles sustituidos en 5' utilizados como agentes antivirales. |
Country Status (9)
Country | Link |
---|---|
US (1) | US5874413A (es) |
EP (1) | EP0845001B1 (es) |
JP (1) | JPH11511170A (es) |
AT (1) | ATE227734T1 (es) |
AU (1) | AU721277B2 (es) |
CA (1) | CA2223814A1 (es) |
DE (1) | DE69624827T2 (es) |
ES (1) | ES2186799T3 (es) |
WO (1) | WO1997007125A1 (es) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20010011075A1 (en) * | 1999-02-05 | 2001-08-02 | Leroy B Townsend | 5'-substituted-ribofuranosyl benzimidazoles as antiviral agents |
GB9600143D0 (en) | 1996-01-05 | 1996-03-06 | Wellcome Found | Therapeutic compounds |
AU2253297A (en) | 1996-01-23 | 1997-08-20 | Regents Of The University Of Michigan, The | Imidazo{1,2-a}pyridine c-nucleosides as antiviral agents |
WO1998035977A1 (en) | 1997-02-13 | 1998-08-20 | Glaxo Group Limited | Benzimidazole derivatives |
US6455506B1 (en) | 1997-07-30 | 2002-09-24 | Smithkline Beecham Corporation | Lyxofuranosyl benzimidazoles as antiviral agents |
AU3883600A (en) | 1999-03-16 | 2000-10-04 | Regents Of The University Of California, The | Glycosylated polyamines |
US6531454B1 (en) | 1999-03-16 | 2003-03-11 | The Regents Of The University Of California | Glycosylated polyamines and methods of use therefor |
GB0008939D0 (en) | 2000-04-11 | 2000-05-31 | Glaxo Group Ltd | Process for preparing substituted benzimidazole compounds |
US20070167353A1 (en) * | 2003-10-24 | 2007-07-19 | John Hilfinger | Prodrug composition |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5248672A (en) * | 1990-11-01 | 1993-09-28 | The Regents Of The University Of Michigan | Polysubstituted benzimidazole nucleosides as antiviral agents |
CA2100863A1 (en) * | 1991-01-23 | 1992-07-24 | David A. Bullough | Adenosine kinase inhibitors |
WO1994008456A1 (en) * | 1992-10-21 | 1994-04-28 | The Regents Of The University Of Michigan | Polysubstituted benzimidazoles as antiviral agents |
GB9413724D0 (en) * | 1994-07-07 | 1994-08-24 | Wellcome Found | Therapeutic nucleosides |
GB9600143D0 (en) * | 1996-01-05 | 1996-03-06 | Wellcome Found | Therapeutic compounds |
-
1996
- 1996-08-16 AT AT96928176T patent/ATE227734T1/de not_active IP Right Cessation
- 1996-08-16 ES ES96928176T patent/ES2186799T3/es not_active Expired - Lifetime
- 1996-08-16 WO PCT/US1996/013187 patent/WO1997007125A1/en active IP Right Grant
- 1996-08-16 US US08/698,715 patent/US5874413A/en not_active Expired - Lifetime
- 1996-08-16 EP EP96928176A patent/EP0845001B1/en not_active Expired - Lifetime
- 1996-08-16 AU AU67745/96A patent/AU721277B2/en not_active Ceased
- 1996-08-16 DE DE69624827T patent/DE69624827T2/de not_active Expired - Fee Related
- 1996-08-16 JP JP9509455A patent/JPH11511170A/ja active Pending
- 1996-08-16 CA CA002223814A patent/CA2223814A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
EP0845001B1 (en) | 2002-11-13 |
ATE227734T1 (de) | 2002-11-15 |
CA2223814A1 (en) | 1997-02-27 |
EP0845001A1 (en) | 1998-06-03 |
DE69624827D1 (de) | 2002-12-19 |
US5874413A (en) | 1999-02-23 |
DE69624827T2 (de) | 2003-09-04 |
AU6774596A (en) | 1997-03-12 |
AU721277B2 (en) | 2000-06-29 |
WO1997007125A1 (en) | 1997-02-27 |
JPH11511170A (ja) | 1999-09-28 |
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