ES2185042T3 - Inhibidores de la trombina. - Google Patents
Inhibidores de la trombina.Info
- Publication number
- ES2185042T3 ES2185042T3 ES97937175T ES97937175T ES2185042T3 ES 2185042 T3 ES2185042 T3 ES 2185042T3 ES 97937175 T ES97937175 T ES 97937175T ES 97937175 T ES97937175 T ES 97937175T ES 2185042 T3 ES2185042 T3 ES 2185042T3
- Authority
- ES
- Spain
- Prior art keywords
- thrombin inhibitors
- thrombin
- inhibitors
- compound
- formula
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US2382996P | 1996-08-12 | 1996-08-12 | |
| GBGB9625311.7A GB9625311D0 (en) | 1996-12-05 | 1996-12-05 | Thrombin inhibitors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2185042T3 true ES2185042T3 (es) | 2003-04-16 |
Family
ID=26310558
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES97937175T Expired - Lifetime ES2185042T3 (es) | 1996-08-12 | 1997-08-08 | Inhibidores de la trombina. |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP0949921B1 (https=) |
| JP (1) | JP2000516929A (https=) |
| AT (1) | ATE227571T1 (https=) |
| AU (1) | AU713527B2 (https=) |
| CA (1) | CA2262686A1 (https=) |
| DE (1) | DE69717147T2 (https=) |
| ES (1) | ES2185042T3 (https=) |
| WO (1) | WO1998006396A1 (https=) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL2178533T3 (pl) | 2007-08-24 | 2013-08-30 | Marinomed Biotechnologie Gmbh | Kompozycja przeciwwirusowa zawierająca siarczanowany polisacharyd: jota-karagen |
| HK1214252A1 (zh) * | 2013-03-15 | 2016-07-22 | Verseon Corporation | 作為凝血酶抑制劑的鹵代吡唑 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6013788A (ja) * | 1983-07-05 | 1985-01-24 | Yamanouchi Pharmaceut Co Ltd | 新規なクマリン誘導体 |
| EP0446604A3 (en) * | 1990-03-16 | 1992-02-19 | American Cyanamid Company | Pyridine and related aza heterocycle derivatives as cardiovascular agents |
| MX9100513A (es) * | 1990-08-06 | 1992-04-01 | Smith Kline French Lab | Compuestos |
| CA2073776A1 (en) * | 1990-11-15 | 1992-05-16 | Joerg Stuerzebecher | Meta-substituted phenyl alanine derivatives |
| US5399564A (en) * | 1991-09-03 | 1995-03-21 | Dowelanco | N-(4-pyridyl or 4-quinolinyl) arylacetamide and 4-(aralkoxy or aralkylamino) pyridine pesticides |
| FR2695387B1 (fr) * | 1992-09-09 | 1994-10-21 | Adir | Nouveaux composés benzopyraniques, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent. |
| US6506876B1 (en) * | 1994-10-11 | 2003-01-14 | G.D. Searle & Co. | LTA4 hydrolase inhibitor pharmaceutical compositions and methods of use |
-
1997
- 1997-08-08 DE DE69717147T patent/DE69717147T2/de not_active Expired - Fee Related
- 1997-08-08 AT AT97937175T patent/ATE227571T1/de not_active IP Right Cessation
- 1997-08-08 AU AU39749/97A patent/AU713527B2/en not_active Ceased
- 1997-08-08 ES ES97937175T patent/ES2185042T3/es not_active Expired - Lifetime
- 1997-08-08 EP EP97937175A patent/EP0949921B1/en not_active Expired - Lifetime
- 1997-08-08 WO PCT/US1997/014019 patent/WO1998006396A1/en not_active Ceased
- 1997-08-08 CA CA002262686A patent/CA2262686A1/en not_active Abandoned
- 1997-08-08 JP JP10509908A patent/JP2000516929A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP0949921A1 (en) | 1999-10-20 |
| CA2262686A1 (en) | 1998-02-19 |
| DE69717147D1 (en) | 2002-12-19 |
| DE69717147T2 (de) | 2003-07-24 |
| AU713527B2 (en) | 1999-12-02 |
| ATE227571T1 (de) | 2002-11-15 |
| WO1998006396A1 (en) | 1998-02-19 |
| JP2000516929A (ja) | 2000-12-19 |
| EP0949921B1 (en) | 2002-11-13 |
| EP0949921A4 (https=) | 1999-10-20 |
| AU3974997A (en) | 1998-03-06 |
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