ES2184735T3 - Peptidos y secuencias de acido nucleico asociados con el virus epstein barr. - Google Patents

Peptidos y secuencias de acido nucleico asociados con el virus epstein barr.

Info

Publication number
ES2184735T3
ES2184735T3 ES93200691T ES93200691T ES2184735T3 ES 2184735 T3 ES2184735 T3 ES 2184735T3 ES 93200691 T ES93200691 T ES 93200691T ES 93200691 T ES93200691 T ES 93200691T ES 2184735 T3 ES2184735 T3 ES 2184735T3
Authority
ES
Spain
Prior art keywords
peptides
nucleic acid
ebv
antibodies
barr virus
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES93200691T
Other languages
English (en)
Inventor
J M Middeldorp
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Biomerieux BV
Original Assignee
Organon Teknika BV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Organon Teknika BV filed Critical Organon Teknika BV
Application granted granted Critical
Publication of ES2184735T3 publication Critical patent/ES2184735T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/081—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from DNA viruses
    • C07K16/085—Herpetoviridae, e.g. pseudorabies virus, Epstein-Barr virus
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/081—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from DNA viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701—Specific hybridization probes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56983—Viruses
    • G01N33/56994—Herpetoviridae, e.g. cytomegalovirus, Epstein-Barr virus
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/61—Fusion polypeptide containing an enzyme fusion for detection (lacZ, luciferase)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
    • C07K2319/735—Fusion polypeptide containing domain for protein-protein interaction containing a domain for self-assembly, e.g. a viral coat protein (includes phage display)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/16011—Herpesviridae
    • C12N2710/16211—Lymphocryptovirus, e.g. human herpesvirus 4, Epstein-Barr Virus
    • C12N2710/16222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Abstract

LA INVENCION DESCRIBE UNOS PEPTIDOS INMUNOQUIMICAMENTE REACTIVOS CON ANTICUERPOS PAR EL VIRUS EPSTEIN-BARR (EBV), QUE COMPRENDEN AL MENOS UNA PARTE DE LA PROTEINA VCA-P18 O VCA-P40, ENCODIFICADA DENTRO DE LOS MARCOS EBV DE LECTURA ABIERTA BFRF3 Y BDRF1 RESPECTIVAMENTE, O UNA DE SUS VARIANTES FUNCIONALES. TAMBIEN SE DESCRIBEN UNAS SECUENCIAS DE ACIDO NUCLEICO QUE ENCODIFICAN ESTOS PEPTIDOS,ANTICUERPOS MONOCLONALES CONTRA LOS MISMOS,LINEAS CELULARES CAPACES DE PRODUCIR ANTICUERPOS MONOCLONALES Y ANTICUERPOS ANTI-IDEOTIPO, ASI COMO LAS MOLECULAS DE VECTOR RECOMBINANTE QUE COMPRENDEN UNA SECUENCIA DE ACIDO NUCLEICO DE ACUERDO CON LA INVENCION Y LAS CELULAS HUESPED TRANSFORMADAS O TRANSFERIDAS CON ESAS MOLECULAS.POR ULTIMO SE DESCRIBEN LOS REAGENTES INMUNOLOGICOS Y LOS METODOS PARA DETECTAR LOS ANTICUERPOS EBV Y ANTI-EBV, Y UN METODO PARA AMPLIFICAR Y DETECTAR EL ACIDO NUCLEICO VIRICO EB.
ES93200691T 1992-03-13 1993-03-10 Peptidos y secuencias de acido nucleico asociados con el virus epstein barr. Expired - Lifetime ES2184735T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP92200721 1992-03-13

Publications (1)

Publication Number Publication Date
ES2184735T3 true ES2184735T3 (es) 2003-04-16

Family

ID=8210477

Family Applications (2)

Application Number Title Priority Date Filing Date
ES93200691T Expired - Lifetime ES2184735T3 (es) 1992-03-13 1993-03-10 Peptidos y secuencias de acido nucleico asociados con el virus epstein barr.
ES02075193T Expired - Lifetime ES2298325T3 (es) 1992-03-13 1993-03-10 Peptidos y secuencias de acido nucleico relacionadas con el virus epstein barr.

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES02075193T Expired - Lifetime ES2298325T3 (es) 1992-03-13 1993-03-10 Peptidos y secuencias de acido nucleico relacionadas con el virus epstein barr.

Country Status (13)

Country Link
US (1) US5424398A (es)
EP (2) EP1225226B1 (es)
JP (3) JP4135996B2 (es)
KR (1) KR100291247B1 (es)
AT (2) ATE222291T1 (es)
AU (1) AU666920B2 (es)
CA (1) CA2092680C (es)
DE (2) DE69334191T2 (es)
DK (2) DK1225226T3 (es)
ES (2) ES2184735T3 (es)
FI (1) FI114802B (es)
PT (1) PT574048E (es)
ZA (1) ZA931797B (es)

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WO2007044033A2 (en) 2004-12-07 2007-04-19 University Of Pittsburgh Of The Commonwealth System Of Higher Education Therapeutic and diagnostic cloned mhc-unrestricted receptor specific for the muc1 tumor associated antigen
WO2007064844A2 (en) 2005-12-01 2007-06-07 Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services Anti-viral griffithsin compounds, compositions, and methods of use
MX2008008233A (es) 2005-12-23 2009-03-27 Univ Lausanne Peptidos sinteticos para utilizarse como inhibidores de secrecion de neurotransmisores y como inductores de relajacion muscular.
US7868228B2 (en) 2006-01-31 2011-01-11 Monsanto Technology Llc Phosphopantetheinyl transferases from bacteria
US7973142B2 (en) 2006-04-07 2011-07-05 Warner Chilcott Company Antibodies that bind human protein tyrosine phosphatase beta (HPTPβ)
US7795444B2 (en) * 2006-06-27 2010-09-14 Warner Chilcott Company Human protein tyrosine phosphatase inhibitors and methods of use
US7589212B2 (en) * 2006-06-27 2009-09-15 Procter & Gamble Company Human protein tyrosine phosphatase inhibitors and methods of use
US8846685B2 (en) 2006-06-27 2014-09-30 Aerpio Therapeutics Inc. Human protein tyrosine phosphatase inhibitors and methods of use
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Also Published As

Publication number Publication date
JP4106041B2 (ja) 2008-06-25
AU3515293A (en) 1993-09-16
DK0574048T3 (da) 2002-12-16
JP2008261851A (ja) 2008-10-30
FI931109A (fi) 1993-09-14
ATE222291T1 (de) 2002-08-15
EP0574048A2 (en) 1993-12-15
ATE380243T1 (de) 2007-12-15
PT574048E (pt) 2002-12-31
DE69332197D1 (de) 2002-09-19
JP4365440B2 (ja) 2009-11-18
AU666920B2 (en) 1996-02-29
DE69332197T2 (de) 2003-04-17
ZA931797B (en) 1993-09-30
EP1225226A1 (en) 2002-07-24
KR930019829A (ko) 1993-10-19
ES2298325T3 (es) 2008-05-16
CA2092680C (en) 2006-08-08
US5424398A (en) 1995-06-13
KR100291247B1 (ko) 2001-06-01
FI931109A0 (fi) 1993-03-12
DE69334191T2 (de) 2008-11-27
FI114802B (fi) 2004-12-31
DK1225226T3 (da) 2008-04-14
JPH0690787A (ja) 1994-04-05
JP2004261183A (ja) 2004-09-24
JP4135996B2 (ja) 2008-08-20
EP0574048A3 (es) 1994-03-02
EP0574048B1 (en) 2002-08-14
CA2092680A1 (en) 1993-09-14
EP1225226B1 (en) 2007-12-05
DE69334191D1 (de) 2008-01-17

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