ES2181593A1 - Metodo para la obtencion de implantes bioactivos utiles como sistemas de liberacion controlada de antibioticos. - Google Patents
Metodo para la obtencion de implantes bioactivos utiles como sistemas de liberacion controlada de antibioticos.Info
- Publication number
- ES2181593A1 ES2181593A1 ES200101386A ES200101386A ES2181593A1 ES 2181593 A1 ES2181593 A1 ES 2181593A1 ES 200101386 A ES200101386 A ES 200101386A ES 200101386 A ES200101386 A ES 200101386A ES 2181593 A1 ES2181593 A1 ES 2181593A1
- Authority
- ES
- Spain
- Prior art keywords
- implants
- bone
- antibiotics
- systems
- controlled release
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/02—Inorganic materials
- A61L27/10—Ceramics or glasses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/02—Inorganic materials
- A61L27/12—Phosphorus-containing materials, e.g. apatite
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/54—Biologically active materials, e.g. therapeutic substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
- A61L2300/406—Antibiotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
- A61L2300/602—Type of release, e.g. controlled, sustained, slow
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Dermatology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Epidemiology (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Inorganic Chemistry (AREA)
- Ceramic Engineering (AREA)
- Materials For Medical Uses (AREA)
Abstract
Método para la obtención de implantes bioactivos útiles como sistemas de liberación controlada de antibióticos. La invención consiste en un método en el que se lleva a cabo el control del tamaño de grano de un vidrio bioactivo, la mezcla de dicho vidrio con un antibiótico, el conformado de la mezcla aplicando presión de tipo uniaxial y posterior prensado isostático. Se obtienen piezas compactas para ser implantadas en el tejido óseo capaces de proporcionar dosis efectivas de antibiótico a nivel local. Los implantes presentan capacidad para promover la regeneración ósea. De aplicación en cirugía ortopédica para relleno de defectos óseos de cualquier etiología y en la prevención y tratamiento de infecciones óseas de origen bacteriano.
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES200101386A ES2181593B2 (es) | 2001-06-14 | 2001-06-14 | Metodo para la obtencion de implantes bioactivos utiles como sistemas de liberacion controlada de antibioticos. |
PCT/ES2002/000301 WO2002102430A1 (es) | 2001-06-14 | 2002-06-14 | Metodo para la obtencion de implantes bioactivos utiles como sistemas de liberacion controlada de antibioticos |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES200101386A ES2181593B2 (es) | 2001-06-14 | 2001-06-14 | Metodo para la obtencion de implantes bioactivos utiles como sistemas de liberacion controlada de antibioticos. |
Publications (2)
Publication Number | Publication Date |
---|---|
ES2181593A1 true ES2181593A1 (es) | 2003-02-16 |
ES2181593B2 ES2181593B2 (es) | 2004-04-16 |
Family
ID=8498070
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES200101386A Expired - Lifetime ES2181593B2 (es) | 2001-06-14 | 2001-06-14 | Metodo para la obtencion de implantes bioactivos utiles como sistemas de liberacion controlada de antibioticos. |
Country Status (2)
Country | Link |
---|---|
ES (1) | ES2181593B2 (es) |
WO (1) | WO2002102430A1 (es) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9522217B2 (en) | 2000-03-15 | 2016-12-20 | Orbusneich Medical, Inc. | Medical device with coating for capturing genetically-altered cells and methods for using same |
US9364565B2 (en) | 2000-03-15 | 2016-06-14 | Orbusneich Medical, Inc. | Medical device with coating for capturing genetically-altered cells and methods of using same |
ES2393980T3 (es) * | 2003-09-30 | 2013-01-03 | Adc Advanced Dental Care Gmbh & Co Kg | Método para producir un material de sustitución ósea |
CN105497990B (zh) * | 2016-01-14 | 2019-11-29 | 聊城大学 | 一种三维多孔钛基镁掺杂涂层及其制备方法 |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1998011853A1 (en) * | 1996-09-19 | 1998-03-26 | Usbiomaterials Corporation | Composition and method for acceleration of wound and burn healing |
WO1998040113A1 (en) * | 1997-03-13 | 1998-09-17 | University Of Florida Tissue Bank, Inc. | Bone paste |
US5874109A (en) * | 1994-07-27 | 1999-02-23 | The Trustees Of The University Of Pennsylvania | Incorporation of biological molecules into bioactive glasses |
-
2001
- 2001-06-14 ES ES200101386A patent/ES2181593B2/es not_active Expired - Lifetime
-
2002
- 2002-06-14 WO PCT/ES2002/000301 patent/WO2002102430A1/es not_active Application Discontinuation
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5874109A (en) * | 1994-07-27 | 1999-02-23 | The Trustees Of The University Of Pennsylvania | Incorporation of biological molecules into bioactive glasses |
WO1998011853A1 (en) * | 1996-09-19 | 1998-03-26 | Usbiomaterials Corporation | Composition and method for acceleration of wound and burn healing |
WO1998040113A1 (en) * | 1997-03-13 | 1998-09-17 | University Of Florida Tissue Bank, Inc. | Bone paste |
Non-Patent Citations (2)
Title |
---|
ARCOS et al. "Bioactivity in glass/PMMA composites used as drug delivery system", Biomaterials, abril 2001, volumen 2, nö 7, páginas 701-708, ISSN 0142-9612. * |
RAGEL et al. "In vitro bioactivity and gentamicine release from glass-polymer-antibiotics composites", J. Biomed. Mat. Res., septiembre 2000, volumen 51, nö 3, páginas 424-429, ISSN 0021-9304. * |
Also Published As
Publication number | Publication date |
---|---|
ES2181593B2 (es) | 2004-04-16 |
WO2002102430A1 (es) | 2002-12-27 |
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