ES2171233T3 - Uso de eliprodil para la preparacion de un medicamento para el tratamiento de trastornos isquemicos de la retina o el nervio optico. - Google Patents

Uso de eliprodil para la preparacion de un medicamento para el tratamiento de trastornos isquemicos de la retina o el nervio optico.

Info

Publication number
ES2171233T3
ES2171233T3 ES96943986T ES96943986T ES2171233T3 ES 2171233 T3 ES2171233 T3 ES 2171233T3 ES 96943986 T ES96943986 T ES 96943986T ES 96943986 T ES96943986 T ES 96943986T ES 2171233 T3 ES2171233 T3 ES 2171233T3
Authority
ES
Spain
Prior art keywords
eliprodil
retina
disorders
ischemical
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES96943986T
Other languages
English (en)
Inventor
Michael A Kapin
Louis Desantis Jr
Bernard Scatton
Salomon Langer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Sanofi Synthelabo SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Synthelabo SA filed Critical Sanofi Synthelabo SA
Application granted granted Critical
Publication of ES2171233T3 publication Critical patent/ES2171233T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

SE DESCRIBE EL USO DE ANTAGONISTAS DEL SITIO DE POLIAMINA PARA TRATAR TRASTORNOS ISQUEMICOS DE LA RETINA Y DE LA CABEZA DEL NERVIO OPTICO. SE PREFIEREN ESPECIALMENTE CIERTOS DERIVADOS DE 1 - FENIL - 2 - PIPERIDINOALCANOL, TALES COMO ELIPRODILO Y IFENPRODILO.
ES96943986T 1996-01-02 1996-12-17 Uso de eliprodil para la preparacion de un medicamento para el tratamiento de trastornos isquemicos de la retina o el nervio optico. Expired - Lifetime ES2171233T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US58200396A 1996-01-02 1996-01-02

Publications (1)

Publication Number Publication Date
ES2171233T3 true ES2171233T3 (es) 2002-09-01

Family

ID=24327451

Family Applications (1)

Application Number Title Priority Date Filing Date
ES96943986T Expired - Lifetime ES2171233T3 (es) 1996-01-02 1996-12-17 Uso de eliprodil para la preparacion de un medicamento para el tratamiento de trastornos isquemicos de la retina o el nervio optico.

Country Status (12)

Country Link
US (1) US6020352A (es)
EP (1) EP0871446B1 (es)
JP (1) JP2000507205A (es)
AT (1) ATE214605T1 (es)
AU (1) AU716670B2 (es)
CA (1) CA2241913A1 (es)
DE (1) DE69620027T2 (es)
DK (1) DK0871446T3 (es)
ES (1) ES2171233T3 (es)
HK (1) HK1016068A1 (es)
PT (1) PT871446E (es)
WO (1) WO1997024123A1 (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9620350D0 (en) 1996-09-30 1996-11-13 Maudsley David J Cancer vaccine
JP2002528416A (ja) * 1998-10-27 2002-09-03 アルコン ラボラトリーズ， インコーポレーテッド 外網膜の疾患の治療
US20030212107A1 (en) * 2001-05-10 2003-11-13 Kapin Michael A. R-reliprodil for treating glaucoma
WO2005080394A1 (en) * 2004-02-24 2005-09-01 Bioaxone Therapeutique Inc. 4-substituted piperidine derivatives
GB2432526A (en) * 2005-11-24 2007-05-30 Arakis Ltd Use of ifenprodil for the treatment of ophthalmic diseases
US10149856B2 (en) 2015-01-26 2018-12-11 BioAxone BioSciences, Inc. Treatment of cerebral cavernous malformations and cerebral aneurysms with rho kinase inhibitors
US10857157B2 (en) 2015-01-26 2020-12-08 BioAxone BioSciences, Inc. Treatment of cerebral cavernous malformations and cerebral aneurysms with rho kinase inhibitors
US10106525B2 (en) 2015-01-26 2018-10-23 BioAxone BioSciences, Inc. Rho kinase inhibitor BA-1049 (R) and active metabolites thereof
US11198680B2 (en) 2016-12-21 2021-12-14 BioAxone BioSciences, Inc. Rho kinase inhibitor BA-1049 (R) and active metabolites thereof
US10537567B2 (en) 2017-07-11 2020-01-21 BioAxone BioSciences, Inc. Kinase inhibitors for treatment of disease

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2534580A1 (fr) * 1982-10-13 1984-04-20 Synthelabo Derives de phenyl-1 piperidino-2 propanol, leur preparation, et medicaments qui les contiennent
US5922773A (en) * 1992-12-04 1999-07-13 The Children's Medical Center Corp. Glaucoma treatment

Also Published As

Publication number Publication date
DK0871446T3 (da) 2002-04-15
AU1373997A (en) 1997-07-28
PT871446E (pt) 2002-08-30
HK1016068A1 (en) 1999-10-29
CA2241913A1 (en) 1997-07-10
US6020352A (en) 2000-02-01
DE69620027D1 (de) 2002-04-25
EP0871446A1 (en) 1998-10-21
ATE214605T1 (de) 2002-04-15
WO1997024123A1 (en) 1997-07-10
DE69620027T2 (de) 2002-09-05
EP0871446B1 (en) 2002-03-20
JP2000507205A (ja) 2000-06-13
AU716670B2 (en) 2000-03-02

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