ES2170435T3 - Procedimiento para la preparacion de acido tioctico seco. - Google Patents

Procedimiento para la preparacion de acido tioctico seco.

Info

Publication number
ES2170435T3
ES2170435T3 ES98110600T ES98110600T ES2170435T3 ES 2170435 T3 ES2170435 T3 ES 2170435T3 ES 98110600 T ES98110600 T ES 98110600T ES 98110600 T ES98110600 T ES 98110600T ES 2170435 T3 ES2170435 T3 ES 2170435T3
Authority
ES
Spain
Prior art keywords
procedure
preparation
thioctic acid
lipoic
dry
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES98110600T
Other languages
English (en)
Inventor
Herbert Dr Tanner
Karlheinz Prof Drauz
Gerhard Dr Sator
Horst Bethge
Roland Moller
Frank Dr Hubner
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Meda Pharma GmbH and Co KG
Original Assignee
Viatris GmbH and Co KG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Viatris GmbH and Co KG filed Critical Viatris GmbH and Co KG
Application granted granted Critical
Publication of ES2170435T3 publication Critical patent/ES2170435T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D339/00—Heterocyclic compounds containing rings having two sulfur atoms as the only ring hetero atoms
    • C07D339/02—Five-membered rings
    • C07D339/04—Five-membered rings having the hetero atoms in positions 1 and 2, e.g. lipoic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/54—Improvements relating to the production of bulk chemicals using solvents, e.g. supercritical solvents or ionic liquids

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)

Abstract

LA PRESENTE INVENCION TRATA DE UN PROCEDIMIENTO PARA LA OBTENCION DE ACIDO AL - LIPOICO SECO, MEDIANTE EL TRATAMIENTO DE UNA MATERIA PRIMA EN LA QUE SE ENCUENTRA ACIDO AL LIPOICO EN GRAN CANTIDAD CON CO 2 LIQUIDO O POR ENCIMA DEL PUNTO CRITICO, Y SE CONSIGUE DE ESTA MANERA POR UN PROCEDIMIENTO TECNICO SENCILLO OBTENER ACIDO AL - LIPOICO CON BAJOS CONTENIDOS EN DISOLVENTES RESIDUALES.
ES98110600T 1997-06-23 1998-06-10 Procedimiento para la preparacion de acido tioctico seco. Expired - Lifetime ES2170435T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19726519A DE19726519A1 (de) 1997-06-23 1997-06-23 Verfahren zur Herstellung trockener Thioctsäure
CA002254561A CA2254561C (en) 1997-06-23 1998-11-20 Method of producing dry thioctic acid

Publications (1)

Publication Number Publication Date
ES2170435T3 true ES2170435T3 (es) 2002-08-01

Family

ID=32031330

Family Applications (1)

Application Number Title Priority Date Filing Date
ES98110600T Expired - Lifetime ES2170435T3 (es) 1997-06-23 1998-06-10 Procedimiento para la preparacion de acido tioctico seco.

Country Status (10)

Country Link
US (1) US5981767A (es)
EP (1) EP0887347B1 (es)
JP (1) JPH1171369A (es)
AT (1) ATE212626T1 (es)
CA (1) CA2254561C (es)
CY (1) CY1106077T1 (es)
DE (2) DE19726519A1 (es)
DK (1) DK0887347T3 (es)
ES (1) ES2170435T3 (es)
PT (1) PT887347E (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19938621A1 (de) 1999-08-14 2001-02-22 Sueddeutsche Kalkstickstoff Verfahren zur Herstellung von lösemittelfreier alpha-Liponsäure
US20020076470A1 (en) 2000-10-31 2002-06-20 Colgate-Palmolive Company Composition and method
US8669282B2 (en) * 2000-10-31 2014-03-11 Hill's Pet Nutrition, Inc. Companion animal compositions including lipoic acid and methods of use thereof
WO2006071919A2 (en) 2004-12-29 2006-07-06 Hill's Pet Nutrition, Inc. Methods for inhibiting a decline in learning and/or memory in animals
US8252742B2 (en) 2004-12-30 2012-08-28 Hill's Pet Nutrition, Inc. Methods for enhancing the quality of life of a senior animal
CA2592844C (en) 2004-12-30 2012-10-09 Hill's Pet Nutrition, Inc. Methods for enhancing the quality of life of a senior animal
CA2615060C (en) * 2005-07-14 2016-06-21 Hill's Pet Nutrition, Inc. Method for prolonging the life of animals
CN100375745C (zh) * 2005-12-21 2008-03-19 重庆药友制药有限责任公司 硫辛酸的精制方法
CN100387593C (zh) * 2006-01-26 2008-05-14 南京师范大学 连续逆流液液萃取分离二硫辛酸与乙醇及碱水溶液的方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4037440A1 (de) * 1990-11-24 1992-05-27 Basf Ag Verfahren zur herstellung von (6s)-6,8-dihydroxyoctansaeureestern
DE4229914A1 (de) * 1992-09-08 1994-03-10 Basf Ag Verbessertes Verfahren zur Herstellung von R/S-Ï-Liponsäure oder R/S-â-Liponsäure
DE4235912C2 (de) * 1992-10-23 2002-12-05 Viatris Gmbh Verfahren zur Herstellung kristalliner Thioctsäure und deren Verwendung
DE19510130C1 (de) * 1995-03-21 1996-11-21 Asta Medica Ag Verfahren zur Herstellung rieselfähiger R,S-Thioctsäure, R,S-Thioctsäure sowie deren Verwendung

Also Published As

Publication number Publication date
US5981767A (en) 1999-11-09
CA2254561A1 (en) 2000-05-20
JPH1171369A (ja) 1999-03-16
DE59802942D1 (de) 2002-03-14
ATE212626T1 (de) 2002-02-15
EP0887347B1 (de) 2002-01-30
CY1106077T1 (el) 2011-04-06
EP0887347A1 (de) 1998-12-30
DK0887347T3 (da) 2002-04-29
PT887347E (pt) 2002-11-29
CA2254561C (en) 2006-09-26
DE19726519A1 (de) 1998-12-24

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