ES2169038T3 - Compuestos y composiciones de sintesis con una capacidad de union celular mejorada. - Google Patents
Compuestos y composiciones de sintesis con una capacidad de union celular mejorada.Info
- Publication number
- ES2169038T3 ES2169038T3 ES93900817T ES93900817T ES2169038T3 ES 2169038 T3 ES2169038 T3 ES 2169038T3 ES 93900817 T ES93900817 T ES 93900817T ES 93900817 T ES93900817 T ES 93900817T ES 2169038 T3 ES2169038 T3 ES 2169038T3
- Authority
- ES
- Spain
- Prior art keywords
- compositions
- collagen
- cell
- improved cellular
- synthesis compounds
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/0068—General culture methods using substrates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/30—Synthetic polymers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/50—Proteins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/50—Proteins
- C12N2533/54—Collagen; Gelatin
Abstract
LAS COMPOSICIONES DEL INVENTO INCLUYEN COMPUESTOS QUE COMPRENDEN UNOS COMPONENTES PORTADORES DE BIOMATERIAL CON UNION DE CELULA INCREMENTADO CON RESPECTO AL COLAGENO. ESOS COMPUESTOS SON UTILES PARA LA REPARACION O RECONSTRUCCION DE PAPEL DURO Y BLANDO. COMPONENTES OPORTUNOS CON UNION DE CELULA INCREMENTADO INCLUYE PEPTIDOS SINTETICOS QUE IMITAN LA CONFORMACION NECESARIA PARA RECONOCER Y CLASIFICAR LAS ESPECIES DE UNION DE COLAGENO (TAL COMO RECEPTORES DE SUPERFICIE DE CELULA PARA COLAGENO Y FIBRONECTIN). MATRICES HIDROGEL COMO EL BIOMATERIAL PROMUEVEN LIGAR LA CELULA A LA MATRIZ Y LA MIGRACION DE LA CELULA DENTRO DE LA MATRIZ.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/804,782 US5354736A (en) | 1989-08-14 | 1991-12-09 | Synthetic compounds and compositions with enhanced cell binding |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2169038T3 true ES2169038T3 (es) | 2002-07-01 |
Family
ID=25189820
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES93900817T Expired - Lifetime ES2169038T3 (es) | 1991-12-09 | 1992-12-03 | Compuestos y composiciones de sintesis con una capacidad de union celular mejorada. |
Country Status (8)
Country | Link |
---|---|
US (1) | US5354736A (es) |
EP (1) | EP0618802B1 (es) |
JP (1) | JPH07501553A (es) |
AT (1) | ATE207532T1 (es) |
CA (1) | CA2124583C (es) |
DE (1) | DE69232153T2 (es) |
ES (1) | ES2169038T3 (es) |
WO (1) | WO1993011781A1 (es) |
Families Citing this family (42)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5635482A (en) | 1989-08-14 | 1997-06-03 | The Regents Of The University Of California | Synthetic compounds and compositions with enhanced cell binding |
US5674848A (en) * | 1989-08-14 | 1997-10-07 | The Regents Of The University Of California | Bioreactor compositions with enhanced cell binding |
US20030077825A1 (en) * | 1994-07-22 | 2003-04-24 | Bhatnagar Rajendra S. | Structures useful for bone engineering and methods |
US5709854A (en) * | 1993-04-30 | 1998-01-20 | Massachusetts Institute Of Technology | Tissue formation by injecting a cell-polymeric solution that gels in vivo |
US5776747A (en) * | 1994-07-20 | 1998-07-07 | Cytotherapeutics, Inc. | Method for controlling the distribution of cells within a bioartificial organ using polycthylene oxide-poly (dimethylsiloxane) copolymer |
US5834029A (en) * | 1994-07-20 | 1998-11-10 | Cytotherapeutics, Inc. | Nerve guidance channel containing bioartificial three-dimensional hydrogel extracellular matrix derivatized with cell adhesive peptide fragment |
US6638912B2 (en) * | 1995-05-01 | 2003-10-28 | The Regents Of The University Of California | Peptide compositions mimicking TGF-β activity |
US5780436A (en) * | 1995-05-01 | 1998-07-14 | The Regents Of The University Of California | Peptide compositions with growth factor-like activity |
US5861032A (en) * | 1996-01-31 | 1999-01-19 | Surface Genesis, Inc. | Medical device having a biocompatible coating and oxidation method of coupling therefor |
EP0953040A4 (en) | 1996-04-26 | 2001-12-12 | Univ Case Western Reserve | SKIN REGENERATION USING MESENCHYMAL STEM CELLS |
US5914121A (en) * | 1997-02-12 | 1999-06-22 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Formation of human bone in vivo using ceramic powder and human marrow stromal fibroblasts |
EP0983096A2 (en) * | 1997-05-16 | 2000-03-08 | Novartis AG | Collagen-like polymers with cell binding activity |
GB9714276D0 (en) | 1997-07-08 | 1997-09-10 | Univ Dundee | Peptides and related compounds |
AU1434799A (en) | 1997-10-21 | 1999-05-10 | Gerolf Gehl | Implant made of a reabsorbable ceramic material |
US6224630B1 (en) | 1998-05-29 | 2001-05-01 | Advanced Bio Surfaces, Inc. | Implantable tissue repair device |
US7004970B2 (en) | 1999-10-20 | 2006-02-28 | Anulex Technologies, Inc. | Methods and devices for spinal disc annulus reconstruction and repair |
US7935147B2 (en) | 1999-10-20 | 2011-05-03 | Anulex Technologies, Inc. | Method and apparatus for enhanced delivery of treatment device to the intervertebral disc annulus |
US8632590B2 (en) | 1999-10-20 | 2014-01-21 | Anulex Technologies, Inc. | Apparatus and methods for the treatment of the intervertebral disc |
US7615076B2 (en) | 1999-10-20 | 2009-11-10 | Anulex Technologies, Inc. | Method and apparatus for the treatment of the intervertebral disc annulus |
US7951201B2 (en) | 1999-10-20 | 2011-05-31 | Anulex Technologies, Inc. | Method and apparatus for the treatment of the intervertebral disc annulus |
US6592625B2 (en) | 1999-10-20 | 2003-07-15 | Anulex Technologies, Inc. | Spinal disc annulus reconstruction method and spinal disc annulus stent |
US7052516B2 (en) | 1999-10-20 | 2006-05-30 | Anulex Technologies, Inc. | Spinal disc annulus reconstruction method and deformable spinal disc annulus stent |
US8128698B2 (en) | 1999-10-20 | 2012-03-06 | Anulex Technologies, Inc. | Method and apparatus for the treatment of the intervertebral disc annulus |
US6805695B2 (en) | 2000-04-04 | 2004-10-19 | Spinalabs, Llc | Devices and methods for annular repair of intervertebral discs |
US20040043398A1 (en) * | 2002-04-15 | 2004-03-04 | Demetrio Sanchez-Martinez | Use of the multipin platform as anchor device |
US8876532B2 (en) | 2002-07-31 | 2014-11-04 | Dentsply International Inc. | Bone repair putty |
US20050063937A1 (en) * | 2003-09-16 | 2005-03-24 | Cheng Li | Multiple-arm peptide compounds, methods of manufacture and use in therapy |
US9763977B2 (en) | 2003-09-16 | 2017-09-19 | Incube Labs, Llc | In vitro bio-reactor circuit |
US8329202B2 (en) * | 2004-11-12 | 2012-12-11 | Depuy Products, Inc. | System and method for attaching soft tissue to an implant |
US20060293228A1 (en) * | 2005-06-24 | 2006-12-28 | Bhatnagar Rajendra S | Therapeutic compositions and methods using transforming growth factor-beta mimics |
US20060293227A1 (en) * | 2005-06-24 | 2006-12-28 | Bhatnagar Rajendra S | Cosmetic compositions and methods using transforming growth factor-beta mimics |
US8048443B2 (en) * | 2005-12-16 | 2011-11-01 | Cerapedics, Inc. | Pliable medical device and method of use |
CA2634245C (en) * | 2005-12-28 | 2013-12-10 | Dentsply International Inc. | Light-curable bone growth material for treating dental bone defects |
US7807624B2 (en) * | 2006-01-11 | 2010-10-05 | Affinergy, Inc. | Methods and compositions for promoting attachment of cells of endothelial cell lineage to medical devices |
US8163022B2 (en) | 2008-10-14 | 2012-04-24 | Anulex Technologies, Inc. | Method and apparatus for the treatment of the intervertebral disc annulus |
US8652153B2 (en) | 2010-01-11 | 2014-02-18 | Anulex Technologies, Inc. | Intervertebral disc annulus repair system and bone anchor delivery tool |
WO2014117107A1 (en) | 2013-01-28 | 2014-07-31 | Cartiva, Inc. | Systems and methods for orthopedic repair |
US9737294B2 (en) | 2013-01-28 | 2017-08-22 | Cartiva, Inc. | Method and system for orthopedic repair |
JP6851965B2 (ja) | 2014-09-26 | 2021-03-31 | サハイ バートナガール ラジェンドラ | 疾患及び障害の治療のためのnfカッパb活性の阻害剤 |
EP3530294A1 (en) | 2018-02-22 | 2019-08-28 | DSM IP Assets B.V. | Processes for coating inorganic particles with a peptide or protein useful for improving cellular activity related to bone growth |
US11235086B2 (en) | 2018-02-22 | 2022-02-01 | Cerapedics, Inc. | Processes for coating inorganic particles with a peptide or protein useful for improving cellular activity related to bone growth |
CN114306731B (zh) * | 2021-12-28 | 2022-10-14 | 中国科学院上海硅酸盐研究所 | 多细胞打印神经化骨再生的活性支架及其制备方法和应用 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4060081A (en) * | 1975-07-15 | 1977-11-29 | Massachusetts Institute Of Technology | Multilayer membrane useful as synthetic skin |
US4992226A (en) * | 1985-03-28 | 1991-02-12 | Collagen Corporation | Method of making molds with xenogeneic collagen/mineral preparations for bone repair |
US5034352A (en) * | 1985-06-25 | 1991-07-23 | Lifecore Biomedical, Inc. | Calcium phosphate materials |
US4994081A (en) * | 1986-10-16 | 1991-02-19 | Cbs Lens | Method for locating on a cornea an artificial lens fabricated from a collagen-hydrogel for promoting epithelial cell growth |
US5007934A (en) * | 1987-07-20 | 1991-04-16 | Regen Corporation | Prosthetic meniscus |
EP0487617B1 (en) * | 1989-08-14 | 1996-10-02 | The Regents Of The University Of California | Synthetic peptides that enhance cell binding |
-
1991
- 1991-12-09 US US07/804,782 patent/US5354736A/en not_active Expired - Lifetime
-
1992
- 1992-12-03 EP EP93900817A patent/EP0618802B1/en not_active Expired - Lifetime
- 1992-12-03 JP JP5510962A patent/JPH07501553A/ja active Pending
- 1992-12-03 DE DE69232153T patent/DE69232153T2/de not_active Expired - Lifetime
- 1992-12-03 AT AT93900817T patent/ATE207532T1/de active
- 1992-12-03 ES ES93900817T patent/ES2169038T3/es not_active Expired - Lifetime
- 1992-12-03 WO PCT/US1992/010420 patent/WO1993011781A1/en active IP Right Grant
- 1992-12-03 CA CA2124583A patent/CA2124583C/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
WO1993011781A1 (en) | 1993-06-24 |
US5354736A (en) | 1994-10-11 |
CA2124583A1 (en) | 1993-06-24 |
EP0618802B1 (en) | 2001-10-24 |
DE69232153D1 (de) | 2001-11-29 |
JPH07501553A (ja) | 1995-02-16 |
EP0618802A4 (en) | 1996-12-18 |
ATE207532T1 (de) | 2001-11-15 |
CA2124583C (en) | 2010-08-10 |
EP0618802A1 (en) | 1994-10-12 |
DE69232153T2 (de) | 2002-06-27 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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