ES2166608T3 - Formulacion de lagrimas artificiales. - Google Patents

Formulacion de lagrimas artificiales.

Info

Publication number
ES2166608T3
ES2166608T3 ES98937631T ES98937631T ES2166608T3 ES 2166608 T3 ES2166608 T3 ES 2166608T3 ES 98937631 T ES98937631 T ES 98937631T ES 98937631 T ES98937631 T ES 98937631T ES 2166608 T3 ES2166608 T3 ES 2166608T3
Authority
ES
Spain
Prior art keywords
tears
formulation
present
artificial tears
dry
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES98937631T
Other languages
English (en)
Inventor
John Michael Tiffany
Beatrix Valeria Macey-Dare
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Oxford University Innovation Ltd
Original Assignee
Oxford University Innovation Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Oxford University Innovation Ltd filed Critical Oxford University Innovation Ltd
Application granted granted Critical
Publication of ES2166608T3 publication Critical patent/ES2166608T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

La presente invención proporciona formulaciones adecuadas para aplicar en los ojos de mamíferos que contiene una proteína lipídica de unión y un lípido polar, presente en forma de complejo soluble en un electrolito acuoso. Las formulaciones descritas presentan propiedades de fluidificación (viscosidad no newtoniana) y de tensión superficial similares a las lágrimas naturales y que se utilizan, por lo tanto, como sustitutos artificiales de lágrimas para el tratamiento de los ojos secos (por ejemplo, queratoconjuntivitis seca) y se utilizan en aplicaciones oftálmicas en general.
ES98937631T 1997-08-01 1998-07-31 Formulacion de lagrimas artificiales. Expired - Lifetime ES2166608T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9716376.0A GB9716376D0 (en) 1997-08-01 1997-08-01 Artificial tear formulation

Publications (1)

Publication Number Publication Date
ES2166608T3 true ES2166608T3 (es) 2002-04-16

Family

ID=10816887

Family Applications (1)

Application Number Title Priority Date Filing Date
ES98937631T Expired - Lifetime ES2166608T3 (es) 1997-08-01 1998-07-31 Formulacion de lagrimas artificiales.

Country Status (5)

Country Link
EP (1) EP1001745B1 (es)
DE (1) DE69802541T2 (es)
ES (1) ES2166608T3 (es)
GB (1) GB9716376D0 (es)
WO (1) WO1999006022A1 (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6565861B1 (en) 2000-02-11 2003-05-20 Isis Innovation Limited Artificial tear formulation
WO2005077337A2 (en) * 2004-02-05 2005-08-25 Baxter International Inc. Dispersions prepared by use of self-stabilizing agents
FR2871059B1 (fr) * 2004-06-03 2007-01-05 Oreal Composition artificielle de type fluide lacrymal et son utilisation.
BR112014014378A2 (pt) * 2011-12-12 2020-05-19 Univ Illinois composição e uso da mesma para tratar doença ocular relacionada a ácido nucleico

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2627386A1 (fr) * 1988-02-22 1989-08-25 Serge Liotet Composition a usage externe destinee a l'administration oculaire
US5174988A (en) * 1989-07-27 1992-12-29 Scientific Development & Research, Inc. Phospholipid delivery system
JPH05503527A (ja) * 1990-02-22 1993-06-10 マクノート・ピーティーワイ・リミテッド 人工涙液
US5652209A (en) * 1994-04-29 1997-07-29 University Of Miami Use of secretory products of human lacrimal gland acinar epithelia for tear replacement therapy

Also Published As

Publication number Publication date
DE69802541T2 (de) 2002-06-13
EP1001745A1 (en) 2000-05-24
EP1001745B1 (en) 2001-11-14
WO1999006022A1 (en) 1999-02-11
DE69802541D1 (de) 2001-12-20
GB9716376D0 (en) 1997-10-08

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