ES2158809A1 - New phenylsulfonate compounds are cyclooxygenase II inhibitors used for treating e.g. inflammation and Alzheimer's disease - Google Patents
New phenylsulfonate compounds are cyclooxygenase II inhibitors used for treating e.g. inflammation and Alzheimer's diseaseInfo
- Publication number
- ES2158809A1 ES2158809A1 ES009902286A ES9902286A ES2158809A1 ES 2158809 A1 ES2158809 A1 ES 2158809A1 ES 009902286 A ES009902286 A ES 009902286A ES 9902286 A ES9902286 A ES 9902286A ES 2158809 A1 ES2158809 A1 ES 2158809A1
- Authority
- ES
- Spain
- Prior art keywords
- new
- phenylsulfonate
- compounds
- cyclooxygenase
- alzheimer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
New phenylsulfonate compounds (I) are new. Phenylsulfonate compounds of formula (I) and their salts and solvates are new. D = C(R2)(R3), C(R4)(R5), C(R2)=(C(R4) or C=C A = CO, O, S or NH, and E = halo, 1-6C alkyl, 2-6C alkenyl or 2-6C alkynyl. N.B. Z and R1-R5 are not defined.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES9902286A ES2158809B1 (en) | 1999-10-18 | 1999-10-18 | NEW SULFONATED DERIVATIVES AS INHIBITORS OF CYCLLOXYGENASA II. |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES9902286A ES2158809B1 (en) | 1999-10-18 | 1999-10-18 | NEW SULFONATED DERIVATIVES AS INHIBITORS OF CYCLLOXYGENASA II. |
Publications (2)
Publication Number | Publication Date |
---|---|
ES2158809A1 true ES2158809A1 (en) | 2001-09-01 |
ES2158809B1 ES2158809B1 (en) | 2002-03-16 |
Family
ID=8310282
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES9902286A Expired - Fee Related ES2158809B1 (en) | 1999-10-18 | 1999-10-18 | NEW SULFONATED DERIVATIVES AS INHIBITORS OF CYCLLOXYGENASA II. |
Country Status (1)
Country | Link |
---|---|
ES (1) | ES2158809B1 (en) |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES464483A1 (en) * | 1976-11-25 | 1978-09-01 | Ciba Geigy | Anti-inflammatory 2-sulphonyl- (or -sulphinyl)-2'-aminoacetophenones |
EP0273369A2 (en) * | 1986-12-31 | 1988-07-06 | Fujisawa Pharmaceutical Co., Ltd. | New alkanesulfonanilide derivatives, processes for preparation thereof and pharmaceutical composition comprising the same |
WO1996026921A1 (en) * | 1995-03-01 | 1996-09-06 | Toyama Chemical Co., Ltd. | Novel biphenyl derivatives or salts thereof, and anti-inflammatory agents containing the same |
-
1999
- 1999-10-18 ES ES9902286A patent/ES2158809B1/en not_active Expired - Fee Related
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES464483A1 (en) * | 1976-11-25 | 1978-09-01 | Ciba Geigy | Anti-inflammatory 2-sulphonyl- (or -sulphinyl)-2'-aminoacetophenones |
EP0273369A2 (en) * | 1986-12-31 | 1988-07-06 | Fujisawa Pharmaceutical Co., Ltd. | New alkanesulfonanilide derivatives, processes for preparation thereof and pharmaceutical composition comprising the same |
WO1996026921A1 (en) * | 1995-03-01 | 1996-09-06 | Toyama Chemical Co., Ltd. | Novel biphenyl derivatives or salts thereof, and anti-inflammatory agents containing the same |
Non-Patent Citations (1)
Title |
---|
GILES KLOPMAN y OREST T. MACINA. Computer-Automated Structure Evaluation of Antileukemic 9-Anilinoacridines. Molecular Pharmacology, 1987, Vol. 31, No 4, paginas 457-476. Pagina 459, compuesto 32, RN 66147-71-5 * |
Also Published As
Publication number | Publication date |
---|---|
ES2158809B1 (en) | 2002-03-16 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
EC2A | Search report published |
Date of ref document: 20010120 Kind code of ref document: A1 Effective date: 20010120 |
|
FD1A | Patent lapsed |
Effective date: 20100312 |