ES2157822A1 - Procedimiento para la sintesis de 2-imidazolidinonas poli-sustituidas. - Google Patents

Procedimiento para la sintesis de 2-imidazolidinonas poli-sustituidas.

Info

Publication number
ES2157822A1
ES2157822A1 ES009901895A ES9901895A ES2157822A1 ES 2157822 A1 ES2157822 A1 ES 2157822A1 ES 009901895 A ES009901895 A ES 009901895A ES 9901895 A ES9901895 A ES 9901895A ES 2157822 A1 ES2157822 A1 ES 2157822A1
Authority
ES
Spain
Prior art keywords
imidazolidinone
polysubstituted
synthesis
substances
isocyanates
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES009901895A
Other languages
English (en)
Other versions
ES2157822B1 (es
Inventor
Moya Antonio Guirado
Pignatelli Raquel Andreu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kylolab S L
Original Assignee
Kylolab S L
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kylolab S L filed Critical Kylolab S L
Priority to ES9901895A priority Critical patent/ES2157822B1/es
Publication of ES2157822A1 publication Critical patent/ES2157822A1/es
Application granted granted Critical
Publication of ES2157822B1 publication Critical patent/ES2157822B1/es
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Landscapes

  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Procedimiento para la síntesis de 2-imidazolidinonas, poli- sustituidas. La presente invención se refiere a un procedimiento para la síntesis de 2-imidazolidinonas de fórmula general (I) (donde R1, R2, y R3 representan cualquier sustituyente orgánico), que implica la reacción de 2-oxazolinas, sustituidas, con sulfonilisocianatos. Se ha aplicado con éxito para preparar 2- imidazolidinonas sustituidas desconocidas con alto rendimiento. La estructura de la 4-benzamido-3-metil-1-tosil-2-imidazolidinona ha sido determinada por rayos cristalografía de X.
ES9901895A 1999-08-17 1999-08-17 Procedimiento para la sintesis de 2-imidazolidinonas poli-sustituidas. Expired - Fee Related ES2157822B1 (es)

Priority Applications (1)

Application Number Priority Date Filing Date Title
ES9901895A ES2157822B1 (es) 1999-08-17 1999-08-17 Procedimiento para la sintesis de 2-imidazolidinonas poli-sustituidas.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES9901895A ES2157822B1 (es) 1999-08-17 1999-08-17 Procedimiento para la sintesis de 2-imidazolidinonas poli-sustituidas.

Publications (2)

Publication Number Publication Date
ES2157822A1 true ES2157822A1 (es) 2001-08-16
ES2157822B1 ES2157822B1 (es) 2002-04-16

Family

ID=8309700

Family Applications (1)

Application Number Title Priority Date Filing Date
ES9901895A Expired - Fee Related ES2157822B1 (es) 1999-08-17 1999-08-17 Procedimiento para la sintesis de 2-imidazolidinonas poli-sustituidas.

Country Status (1)

Country Link
ES (1) ES2157822B1 (es)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4410540A (en) * 1981-11-04 1983-10-18 Merrell Dow Pharmaceuticals Inc. Cardiotonic 4-aroylimidazolidin-2-ones
US5270329A (en) * 1992-12-10 1993-12-14 Eli Lilly And Company Antitumor compositions and methods of treatment

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4410540A (en) * 1981-11-04 1983-10-18 Merrell Dow Pharmaceuticals Inc. Cardiotonic 4-aroylimidazolidin-2-ones
US5270329A (en) * 1992-12-10 1993-12-14 Eli Lilly And Company Antitumor compositions and methods of treatment

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
B. KRIEG, H. LAUTENSCHLÄGER, Oxazolones, I. 4-imidazolin-2-ones by rearrangement of 2-oxo-4-oxazoline-3-carboxamides, Liebigs Ann. Chem., 1976, Vol. 2, paginas 208-220. *
K. KöNIGSBERGER, K. PRASAD, O. REPIC, T.J. BLACLOCK, N-acylimidazolidin-2-ones: new chiral auxiliaries for carboxylic acid alkylation, Tetrahedron: Asymmetry, Vol. 8, No 14, paginas 2347-2354. *
M. REUMAN, A.I. MEYERS, The synthetic utility of oxazolines in aromatic substitution, Tetrahedron, 1985, Vol. 41, No 5, paginas 837-860. *

Also Published As

Publication number Publication date
ES2157822B1 (es) 2002-04-16

Similar Documents

Publication Publication Date Title
TR199801121T2 (xx) Yeni sentez.
HK1105947A1 (en) Trpv1 agonists, formulations containing them and uses thereof trpv1
AU5932300A (en) Synthesis of zsm-5 and zsm-11
CA2537373A1 (en) Selective synthesis of cf3-substituted pyrimidines
CY1106745T1 (el) Μικροσφαιριδια που περιεχουν ενα παραγωγο πλευρομουτιλινης
DE69626981D1 (de) N-(2-oxo-2,3,4,5-tetrahydro-1h-1,5-benzodiazepin-3-yl)-3-amide
EA200200732A1 (ru) Замещенные производные фенилпиперазина, их получение и применение
Alcaide et al. A novel, general, totally stereoselective one-pot synthesis of cis-3-substituted 4-formylazetidin-2-ones
ES2157822A1 (es) Procedimiento para la sintesis de 2-imidazolidinonas poli-sustituidas.
JPS6416791A (en) Guanidine related compound containing substituted tetraphenylborate ion and its production
ATE521346T1 (de) Multifunktionelle carbonate und derivate davon
HK1016599A1 (en) Fused isoindolones as inhibitors of protein kinase c
ZA985769B (en) Chemical process.
AU3814800A (en) Enantiomers of mercapto lactones and processes for their synthesis
SE0001866D0 (sv) A new process
DE3780574D1 (de) 3-substituierte 4-fluorophenyl-1-(fluoroalkoxyphenyl-carbamoyl)-pyrazolin-insektizide.
DE60218774D1 (de) Verfahren zur Herstellung von N,N-carbonyl diimidazol
BRPI0416377A (pt) processo para a sìntese de imidazóis
Larsen et al. Improved Oxidation of the Sulfenamide Functionality: Efficient Synthesis of 6-Ethoxy-2-Benzothiazolesulfonamide
SU659091A3 (ru) Способ получени производных 5-нитроимидазола
HUP0002067A2 (hu) Eljárás imidazolszármazékok előállítására
NO20004956D0 (no) Konvergert syntese av <alfa>-aryl-<beta>-ketonitriler
ES2161602B1 (es) Sintesis de 6-(d-alfa-(bencilidenaminofenilacetamido))penicilanato de 1,1-dioxopenicilanoiloximetilo y analogos. nuevos intermedios para la sintesis de sultamicilina.
CA1252466A (en) METHOD FOR THE PREPARATION OF 1,2,5,6-TETRAHYDRO-4H-PYRROLO[3,2,1-1J]-QUINOLIN-4-ONE; 5-HALOGENO-1,2,3-(1,2-DIHYDROPYRROLO)-4-QUINOLONES, INTERMEDIATE PRODUCTS FOR THIS PREPARATION
RU94031008A (ru) Способ получения замещенных n-3-оксоалкилтиоамидов

Legal Events

Date Code Title Description
EC2A Search report published

Date of ref document: 20010816

Kind code of ref document: A1

Effective date: 20010816

FD1A Patent lapsed

Effective date: 20100311