ES2156725B1 - DERIVATIVES OF DIOXIDES N, N- AND N, X-DISUSTITUTES OF 1,2,6-TIADIAZINE FUSED AND PROCEDURE OF OBTAINING. - Google Patents

DERIVATIVES OF DIOXIDES N, N- AND N, X-DISUSTITUTES OF 1,2,6-TIADIAZINE FUSED AND PROCEDURE OF OBTAINING.

Info

Publication number
ES2156725B1
ES2156725B1 ES9900954A ES9900954A ES2156725B1 ES 2156725 B1 ES2156725 B1 ES 2156725B1 ES 9900954 A ES9900954 A ES 9900954A ES 9900954 A ES9900954 A ES 9900954A ES 2156725 B1 ES2156725 B1 ES 2156725B1
Authority
ES
Spain
Prior art keywords
fused
derivatives
dioxides
procedure
obtaining
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
ES9900954A
Other languages
Spanish (es)
Other versions
ES2156725A1 (en
Inventor
Gil Ana Martinez
Ayuso-Gontan Carmen Gil
Castro Ana Morera
Martin M Concepcion Perez
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Consejo Superior de Investigaciones Cientificas CSIC
Original Assignee
Consejo Superior de Investigaciones Cientificas CSIC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Consejo Superior de Investigaciones Cientificas CSIC filed Critical Consejo Superior de Investigaciones Cientificas CSIC
Priority to ES9900954A priority Critical patent/ES2156725B1/en
Priority to PCT/ES2000/000165 priority patent/WO2000068216A1/en
Priority to AU44063/00A priority patent/AU4406300A/en
Publication of ES2156725A1 publication Critical patent/ES2156725A1/en
Application granted granted Critical
Publication of ES2156725B1 publication Critical patent/ES2156725B1/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C07D285/15—Six-membered rings
    • C07D285/16—Thiadiazines; Hydrogenated thiadiazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/549—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame having two or more nitrogen atoms in the same ring, e.g. hydrochlorothiazide

Abstract

Derivados de dióxidos N,N- y N,X-disustituidos de 1,2,6- tiadiazina fusionadas y procedimiento de obtención. La invención se dirige a los compuestos de fórmula general I, II y III y a su procedimiento de obtención, que se realiza en dos etapas, primeramente los compuestos III y después se obtienen los I y II. Estos compuestos tienen posible aplicación en el campo de las infecciones vírales oportunistas en pacientes inmunocomprometidos.Derivatives of fused N, N- and N, X-disubstituted 1,2,6-thiadiazine dioxides and obtaining procedure. The invention is directed to the compounds of general formula I, II and III and their method of production, which is carried out in two stages, firstly compounds III and then I and II are obtained. These compounds have possible application in the field of opportunistic viral infections in immunocompromised patients.

ES9900954A 1999-05-07 1999-05-07 DERIVATIVES OF DIOXIDES N, N- AND N, X-DISUSTITUTES OF 1,2,6-TIADIAZINE FUSED AND PROCEDURE OF OBTAINING. Expired - Fee Related ES2156725B1 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
ES9900954A ES2156725B1 (en) 1999-05-07 1999-05-07 DERIVATIVES OF DIOXIDES N, N- AND N, X-DISUSTITUTES OF 1,2,6-TIADIAZINE FUSED AND PROCEDURE OF OBTAINING.
PCT/ES2000/000165 WO2000068216A1 (en) 1999-05-07 2000-05-05 Fused 1,2,6-thiadiazine -n,n and n,x-disubstituted dioxide derivatives and corresponding production method
AU44063/00A AU4406300A (en) 1999-05-07 2000-05-05 Fused 1,2,6-thiadiazine -LTiGTn,nLT/iGT and LTiGTn,xLT/iGT-disubstituted dioxidederivatives and corresponding production method

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES9900954A ES2156725B1 (en) 1999-05-07 1999-05-07 DERIVATIVES OF DIOXIDES N, N- AND N, X-DISUSTITUTES OF 1,2,6-TIADIAZINE FUSED AND PROCEDURE OF OBTAINING.

Publications (2)

Publication Number Publication Date
ES2156725A1 ES2156725A1 (en) 2001-07-01
ES2156725B1 true ES2156725B1 (en) 2002-03-01

Family

ID=8308292

Family Applications (1)

Application Number Title Priority Date Filing Date
ES9900954A Expired - Fee Related ES2156725B1 (en) 1999-05-07 1999-05-07 DERIVATIVES OF DIOXIDES N, N- AND N, X-DISUSTITUTES OF 1,2,6-TIADIAZINE FUSED AND PROCEDURE OF OBTAINING.

Country Status (3)

Country Link
AU (1) AU4406300A (en)
ES (1) ES2156725B1 (en)
WO (1) WO2000068216A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0608928D0 (en) 2006-05-08 2006-06-14 Angeletti P Ist Richerche Bio Therapeutic agents
US7718652B2 (en) 2006-12-12 2010-05-18 Wyeth Llc Substituted benzothiadiazinedioxide derivatives and methods of their use
JP2010533698A (en) 2007-07-17 2010-10-28 イステイチユート・デイ・リチエルケ・デイ・ビオロジア・モレコラーレ・ピ・アンジエレツテイ・エツセ・ピー・アー Macrocyclic indole derivatives for the treatment of hepatitis C infection

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2656290A1 (en) * 1976-12-11 1978-06-15 Basf Ag BENZOTHIADIAZINE COMPOUNDS
AU2074699A (en) * 1998-01-26 1999-08-09 Yamanouchi Pharmaceutical Co., Ltd. Novel benzene-fused heterocyclic derivatives or salts thereof

Also Published As

Publication number Publication date
AU4406300A (en) 2000-11-21
WO2000068216A1 (en) 2000-11-16
ES2156725A1 (en) 2001-07-01

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