ES2155685T3 - Utilizacion de deshidroepiandrosterona para el tratamiento de adicciones. - Google Patents
Utilizacion de deshidroepiandrosterona para el tratamiento de adicciones.Info
- Publication number
- ES2155685T3 ES2155685T3 ES97920642T ES97920642T ES2155685T3 ES 2155685 T3 ES2155685 T3 ES 2155685T3 ES 97920642 T ES97920642 T ES 97920642T ES 97920642 T ES97920642 T ES 97920642T ES 2155685 T3 ES2155685 T3 ES 2155685T3
- Authority
- ES
- Spain
- Prior art keywords
- chemical
- sex steroid
- steroid precursor
- addiction
- dheas
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- FMGSKLZLMKYGDP-USOAJAOKSA-N dehydroepiandrosterone Chemical compound C1[C@@H](O)CC[C@]2(C)[C@H]3CC[C@](C)(C(CC4)=O)[C@@H]4[C@@H]3CC=C21 FMGSKLZLMKYGDP-USOAJAOKSA-N 0.000 title abstract 3
- FMGSKLZLMKYGDP-UHFFFAOYSA-N Dehydroepiandrosterone Natural products C1C(O)CCC2(C)C3CCC(C)(C(CC4)=O)C4C3CC=C21 FMGSKLZLMKYGDP-UHFFFAOYSA-N 0.000 title 1
- 229960002847 prasterone Drugs 0.000 title 1
- 239000000126 substance Substances 0.000 abstract 7
- 239000003163 gonadal steroid hormone Substances 0.000 abstract 5
- 239000002243 precursor Substances 0.000 abstract 5
- 206010012335 Dependence Diseases 0.000 abstract 3
- RYYVLZVUVIJVGH-UHFFFAOYSA-N caffeine Chemical compound CN1C(=O)N(C)C(=O)C2=C1N=CN2C RYYVLZVUVIJVGH-UHFFFAOYSA-N 0.000 abstract 2
- ZPUCINDJVBIVPJ-LJISPDSOSA-N cocaine Chemical compound O([C@H]1C[C@@H]2CC[C@@H](N2C)[C@H]1C(=O)OC)C(=O)C1=CC=CC=C1 ZPUCINDJVBIVPJ-LJISPDSOSA-N 0.000 abstract 2
- CZWCKYRVOZZJNM-USOAJAOKSA-N dehydroepiandrosterone sulfate Chemical compound C1[C@@H](OS(O)(=O)=O)CC[C@]2(C)[C@H]3CC[C@](C)(C(CC4)=O)[C@@H]4[C@@H]3CC=C21 CZWCKYRVOZZJNM-USOAJAOKSA-N 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- SNICXCGAKADSCV-JTQLQIEISA-N (-)-Nicotine Chemical compound CN1CCC[C@H]1C1=CC=CN=C1 SNICXCGAKADSCV-JTQLQIEISA-N 0.000 abstract 1
- USSIQXCVUWKGNF-UHFFFAOYSA-N 6-(dimethylamino)-4,4-diphenylheptan-3-one Chemical compound C=1C=CC=CC=1C(CC(C)N(C)C)(C(=O)CC)C1=CC=CC=C1 USSIQXCVUWKGNF-UHFFFAOYSA-N 0.000 abstract 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
- GVGLGOZIDCSQPN-PVHGPHFFSA-N Heroin Chemical compound O([C@H]1[C@H](C=C[C@H]23)OC(C)=O)C4=C5[C@@]12CCN(C)[C@@H]3CC5=CC=C4OC(C)=O GVGLGOZIDCSQPN-PVHGPHFFSA-N 0.000 abstract 1
- LPHGQDQBBGAPDZ-UHFFFAOYSA-N Isocaffeine Natural products CN1C(=O)N(C)C(=O)C2=C1N(C)C=N2 LPHGQDQBBGAPDZ-UHFFFAOYSA-N 0.000 abstract 1
- UAIXRPCCYXNJMQ-RZIPZOSSSA-N buprenorphine hydrochlorie Chemical compound [Cl-].C([C@]12[C@H]3OC=4C(O)=CC=C(C2=4)C[C@@H]2[C@]11CC[C@]3([C@H](C1)[C@](C)(O)C(C)(C)C)OC)C[NH+]2CC1CC1 UAIXRPCCYXNJMQ-RZIPZOSSSA-N 0.000 abstract 1
- 229960001948 caffeine Drugs 0.000 abstract 1
- VJEONQKOZGKCAK-UHFFFAOYSA-N caffeine Natural products CN1C(=O)N(C)C(=O)C2=C1C=CN2C VJEONQKOZGKCAK-UHFFFAOYSA-N 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 229960003920 cocaine Drugs 0.000 abstract 1
- 229960002069 diamorphine Drugs 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 238000001727 in vivo Methods 0.000 abstract 1
- 229960001797 methadone Drugs 0.000 abstract 1
- 229960002715 nicotine Drugs 0.000 abstract 1
- SNICXCGAKADSCV-UHFFFAOYSA-N nicotine Natural products CN1CCCC1C1=CC=CN=C1 SNICXCGAKADSCV-UHFFFAOYSA-N 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
- 229940095172 subutex Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
- A61K31/5685—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone having an oxo group in position 17, e.g. androsterone
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
Abstract
ESTA INVENCION CAPAZ DE SALVAR VIDAS SE REFIERE A UN METODO SENCILLO, SIMPLE E INDOLORO PARA DEJAR DE FUMAR MUY FACILMENTE, CASI SIN DARSE CUENTA, Y TAMBIEN PARA EL TRATAMIENTO CONFORTABLE DE ADICCIONES Y LA DESINTOXICACION CON AYUDA DE PRECURSORES DE ESTEROIDES SEXUALES, COMO LA DESHIDROEPIANDROSTERONA (DHEA) O EL DESHIDROEPIANDROSTERONSULFATO (DHEAS), O ANALOGOS DE ELLOS COMO LA (N) - ALFAFLUORO - O BROMO - EPIANDROSTERONA Y TAMBIEN COMPUESTOS DESTINADOS A CONVERTIRSE IN VIVO EN CUALQUIERA DE LOS PRECURSORES ANTERIORES. ESTOS PRECURSORES PUEDEN, SEGUN ESTA INVENCION, SER INTRODUCIDOS EN LA SANGRE CON RESULTADOS POSITIVOS PARA EL TRATAMIENTO DE UNA ADICCION, COMO POR EJEMPLO LA MENCIONADA ADICION A LA NICOTINA. LA INVENCION SE REFIERE TAMBIEN AL USO DE DESHIDROEPIANDROSTERONA O DESHIDROEPIANDROSTERONSULFATO O ANALOGOS DE ELLOS COMO LA (N) - ALFAFLUORO - O BROMO EPIANDROSTERONA Y TAMBIEN DE COMPUESTOS DESTINADOS A CONVERTIRSE IN VIVO EN CUALQUIERA DE LOS PRECURSORES ANTERIORES, PARA OBTENERP.EJ: LA FABRICACION DE UNA MEDICINA, MENCIONADA PARA SER INTRODUCIDA EN CUALQUIER MODO EN LA SANGRE DE UN CONSUMIDOR DE SUSTANCIAS ADICTIVAS, PARA EL TRATAMIENTO TERAPEUTICO DE UNA ADICCION, COMO POR EJEMPLO LA ADICCION A LA NICOTINA, HACIENDOSE REFERENCIA AL METODO Y AL PRODUCTO COMO : "WISE MAN''S BRAND" O WMB ''97.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NL1002833A NL1002833C2 (nl) | 1996-04-10 | 1996-04-10 | Werkwijze, voor duurzame ontwenning van/aan nicotine en andere verslavende producten door toediening van sex steroide voorlopers (precursors), alsmede het gebruik van die voorlopers als medicijn. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2155685T3 true ES2155685T3 (es) | 2001-05-16 |
Family
ID=19762655
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES97920642T Expired - Lifetime ES2155685T3 (es) | 1996-04-10 | 1997-04-10 | Utilizacion de deshidroepiandrosterona para el tratamiento de adicciones. |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US6194400B1 (es) |
| EP (1) | EP0888116B1 (es) |
| AT (1) | ATE198549T1 (es) |
| AU (1) | AU2695297A (es) |
| DE (1) | DE69703877T2 (es) |
| ES (1) | ES2155685T3 (es) |
| NL (1) | NL1002833C2 (es) |
| WO (1) | WO1997037663A1 (es) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6667299B1 (en) * | 2000-03-16 | 2003-12-23 | Hollis-Eden Pharmaceuticals, Inc. | Pharmaceutical compositions and treatment methods |
| US20080286340A1 (en) * | 2007-05-16 | 2008-11-20 | Sven-Borje Andersson | Buffered nicotine containing products |
| US20080286341A1 (en) * | 2007-05-16 | 2008-11-20 | Sven-Borje Andersson | Buffered coated nicotine containing products |
| US10912806B2 (en) | 2018-09-26 | 2021-02-09 | Michael MCGOWAN | Composition comprising an essential oil and its packaging thereof |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4518595A (en) * | 1983-07-19 | 1985-05-21 | The Jackson Laboratory | Method for treating diabetes using DHEA compounds |
-
1996
- 1996-04-10 NL NL1002833A patent/NL1002833C2/nl not_active IP Right Cessation
-
1997
- 1997-04-10 AU AU26952/97A patent/AU2695297A/en not_active Abandoned
- 1997-04-10 ES ES97920642T patent/ES2155685T3/es not_active Expired - Lifetime
- 1997-04-10 AT AT97920642T patent/ATE198549T1/de not_active IP Right Cessation
- 1997-04-10 WO PCT/EP1997/001779 patent/WO1997037663A1/en not_active Ceased
- 1997-04-10 DE DE69703877T patent/DE69703877T2/de not_active Expired - Fee Related
- 1997-04-10 EP EP97920642A patent/EP0888116B1/en not_active Expired - Lifetime
-
1999
- 1999-04-01 US US09/283,228 patent/US6194400B1/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP0888116B1 (en) | 2001-01-10 |
| WO1997037663A1 (en) | 1997-10-16 |
| NL1002833C2 (nl) | 1997-04-03 |
| NL1002833A1 (nl) | 1996-08-12 |
| ATE198549T1 (de) | 2001-01-15 |
| DE69703877T2 (de) | 2001-08-16 |
| DE69703877D1 (de) | 2001-02-15 |
| EP0888116A1 (en) | 1999-01-07 |
| US6194400B1 (en) | 2001-02-27 |
| AU2695297A (en) | 1997-10-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
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