ES2147646T3 - Composiciones para diagnostico, prevencion y tratamiento de la progresion de los tumores. - Google Patents

Composiciones para diagnostico, prevencion y tratamiento de la progresion de los tumores.

Info

Publication number
ES2147646T3
ES2147646T3 ES96911511T ES96911511T ES2147646T3 ES 2147646 T3 ES2147646 T3 ES 2147646T3 ES 96911511 T ES96911511 T ES 96911511T ES 96911511 T ES96911511 T ES 96911511T ES 2147646 T3 ES2147646 T3 ES 2147646T3
Authority
ES
Spain
Prior art keywords
progression
diagnosis
tumors
prevention
compositions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES96911511T
Other languages
English (en)
Inventor
Andrew W Shyjan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Millennium Pharmaceuticals Inc
Original Assignee
Millennium Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23632952&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2147646(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Millennium Pharmaceuticals Inc filed Critical Millennium Pharmaceuticals Inc
Application granted granted Critical
Publication of ES2147646T3 publication Critical patent/ES2147646T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/82Translation products from oncogenes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/10Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034Isolating an individual clone by screening libraries
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/10Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034Isolating an individual clone by screening libraries
    • C12N15/1072Differential gene expression library synthesis, e.g. subtracted libraries, differential screening
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00Genetically modified animals
    • A01K2217/05Animals comprising random inserted nucleic acids (transgenic)
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00Genetically modified animals
    • A01K2217/07Animals genetically altered by homologous recombination
    • A01K2217/075Animals genetically altered by homologous recombination inducing loss of function, i.e. knock out
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Oncology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

LA PRESENTE INVENCION SE REFIERE A METODOS Y COMPOSICIONES PARA EL DIAGNOSTICO, PREVENCION Y TRATAMIENTO DE LA PROGRESION DE TUMORES EN CELULAS IMPLICADAS EN TUMORES HUMANOS TALES COMO MELANOMAS, DE PECHO, GASTROINTESTINALES, TUMORES PULMONARES Y ESTADOS DE NEOPLASIA TALES COMO LEUCEMIAS Y LINFOMAS. SE HAN IDENTIFICADO GENES QUE SE EXPRESAN DIFERENCIALMENTE EN CELULAS TUMORALES BENIGNAS (ESTO ES, NO MALIGNAS) RESPECTO A CELULAS TUMORALES MALIGNAS QUE EXHIBEN UN ELEVADO POTENCIAL METASTASICO. SE IDENTIFICAN ASIMISMO GENES A TRAVES DE LA CAPACIDAD DE SUS PRODUCTOS GENICOS IMPLICADOS EN LA PROGRESION A, Y/O EN LA AGRESIVIDAD DE, ESTADOS DE ENFERMEDAD POR TUMOR NEOPLASICO.
ES96911511T 1995-03-29 1996-03-29 Composiciones para diagnostico, prevencion y tratamiento de la progresion de los tumores. Expired - Lifetime ES2147646T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/412,431 US5633161A (en) 1995-03-29 1995-03-29 Murine gene fomy030 coding for tumor progression inhibitor

Publications (1)

Publication Number Publication Date
ES2147646T3 true ES2147646T3 (es) 2000-09-16

Family

ID=23632952

Family Applications (1)

Application Number Title Priority Date Filing Date
ES96911511T Expired - Lifetime ES2147646T3 (es) 1995-03-29 1996-03-29 Composiciones para diagnostico, prevencion y tratamiento de la progresion de los tumores.

Country Status (11)

Country Link
US (5) US5633161A (es)
EP (3) EP1006187B1 (es)
AT (2) ATE190982T1 (es)
AU (1) AU708746B2 (es)
CA (1) CA2216717C (es)
DE (2) DE69607332T2 (es)
DK (1) DK0817792T3 (es)
ES (1) ES2147646T3 (es)
GR (1) GR3033478T3 (es)
PT (1) PT817792E (es)
WO (1) WO1996030389A1 (es)

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Also Published As

Publication number Publication date
EP1006187A3 (en) 2000-06-21
AU5437896A (en) 1996-10-16
DE69607332T2 (de) 2000-11-30
EP1006187B1 (en) 2003-09-24
GR3033478T3 (en) 2000-09-29
US5674739A (en) 1997-10-07
EP0817792A1 (en) 1998-01-14
WO1996030389A1 (en) 1996-10-03
CA2216717A1 (en) 1996-10-03
EP0817792B1 (en) 2000-03-22
CA2216717C (en) 2010-05-18
US6372896B1 (en) 2002-04-16
PT817792E (pt) 2000-08-31
ATE250624T1 (de) 2003-10-15
EP1006187A2 (en) 2000-06-07
DK0817792T3 (da) 2000-07-31
US5633161A (en) 1997-05-27
DE69630153D1 (de) 2003-10-30
EP0817792A4 (en) 1998-07-01
DE69630153T2 (de) 2004-06-09
EP1344825A1 (en) 2003-09-17
US6025137A (en) 2000-02-15
DE69607332D1 (de) 2000-04-27
US20050106600A1 (en) 2005-05-19
AU708746B2 (en) 1999-08-12
ATE190982T1 (de) 2000-04-15

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