ES2141123T3 - Preparacion de antitrombina iii. - Google Patents

Preparacion de antitrombina iii.

Info

Publication number
ES2141123T3
ES2141123T3 ES93115422T ES93115422T ES2141123T3 ES 2141123 T3 ES2141123 T3 ES 2141123T3 ES 93115422 T ES93115422 T ES 93115422T ES 93115422 T ES93115422 T ES 93115422T ES 2141123 T3 ES2141123 T3 ES 2141123T3
Authority
ES
Spain
Prior art keywords
antitrombine
powder
antithrombin iii
preparation iii
solvent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES93115422T
Other languages
English (en)
Inventor
Toshinobu Aoyama
Keizou Hirahara
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis KK
Original Assignee
Hoechst Japan Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=17402131&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2141123(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Hoechst Japan Ltd filed Critical Hoechst Japan Ltd
Application granted granted Critical
Publication of ES2141123T3 publication Critical patent/ES2141123T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55Protease inhibitors
    • A61K38/57Protease inhibitors from animals; from humans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/10Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
    • Y10T436/107497Preparation composition [e.g., lysing or precipitation, etc.]
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/10Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
    • Y10T436/108331Preservative, buffer, anticoagulant or diluent

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dermatology (AREA)
  • Molecular Biology (AREA)
  • Diabetes (AREA)
  • Organic Chemistry (AREA)
  • Hematology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Radar Systems Or Details Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

SE DESCRIBEN UNA ANTITROMBINA III QUE CONTIENE UN POLVO LIOFILIZADO DE ANTITROMBINA III Y UN ESTER DE ALKILO DE GLICOLSORBITAN DE POLIOXIETILENO ASI COMO UN KIT COMPUESTO DE UN RECIPIENTE EN DONDE SE COLOCA UN POLVO LIOFILIZADO DE ANTITROMBINA III Y UN SOLVENTE PARA EL POLVO ANTEDICHO QUE SE CARACTERIZA PORQUE EL ESTER DE ALKILO DE GLICOLSORBITAN DE POLIOXIETILENO SE AÑADE BIEN A DICHO POLVO O BIEN A DICHO SOLVENTE O A LOS DOS. ESA PREPARACION TIENE UNA BUENA SOLUBILIDAD EN AGUA AL RETENER SU ACTIVIDAD.
ES93115422T 1992-10-02 1993-09-24 Preparacion de antitrombina iii. Expired - Lifetime ES2141123T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP26436492A JP3494667B2 (ja) 1992-10-02 1992-10-02 アンチトロンビンiii製剤

Publications (1)

Publication Number Publication Date
ES2141123T3 true ES2141123T3 (es) 2000-03-16

Family

ID=17402131

Family Applications (1)

Application Number Title Priority Date Filing Date
ES93115422T Expired - Lifetime ES2141123T3 (es) 1992-10-02 1993-09-24 Preparacion de antitrombina iii.

Country Status (12)

Country Link
US (1) US5385890A (es)
EP (1) EP0590531B1 (es)
JP (1) JP3494667B2 (es)
KR (1) KR100264707B1 (es)
AT (1) ATE188385T1 (es)
AU (1) AU672430B2 (es)
CA (1) CA2107516C (es)
DE (1) DE69327498T2 (es)
DK (1) DK0590531T3 (es)
ES (1) ES2141123T3 (es)
GR (1) GR3032580T3 (es)
PT (1) PT590531E (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994022471A1 (en) * 1993-04-05 1994-10-13 The Green Cross Corporation Liquid antithrombin iii preparation and method of stabilizing the same
AT405905B (de) * 1997-03-25 1999-12-27 Immuno Ag Neue verwendung von antithrombin iii
US6518406B1 (en) * 1999-06-23 2003-02-11 Octapharma Ag Method for purification of proteins
CN114813287A (zh) * 2022-06-29 2022-07-29 深圳市帝迈生物技术有限公司 一种用于肝素抗凝检测的校准品及其制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS597693B2 (ja) * 1978-01-07 1984-02-20 株式会社ミドリ十字 抗トロンビン製剤及びその製法
US4613501A (en) * 1984-12-21 1986-09-23 New York Blood Center, Inc. Inactivation of viruses in labile blood derivatives
US4841023A (en) * 1986-06-25 1989-06-20 New York Blood Center, Inc. Inactivation of viruses in labile protein-containing compositions using fatty acids
US5319072A (en) * 1992-01-10 1994-06-07 Alpha Therapeutic Corporation Human antithrombin-III preparation

Also Published As

Publication number Publication date
EP0590531B1 (en) 2000-01-05
EP0590531A1 (en) 1994-04-06
US5385890A (en) 1995-01-31
GR3032580T3 (en) 2000-05-31
DE69327498D1 (de) 2000-02-10
ATE188385T1 (de) 2000-01-15
CA2107516A1 (en) 1994-04-03
JPH06116167A (ja) 1994-04-26
PT590531E (pt) 2000-05-31
DE69327498T2 (de) 2000-06-08
AU672430B2 (en) 1996-10-03
JP3494667B2 (ja) 2004-02-09
AU4872893A (en) 1994-04-14
KR940008695A (ko) 1994-05-16
KR100264707B1 (ko) 2000-09-01
DK0590531T3 (da) 2000-06-13
CA2107516C (en) 2004-12-07

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