ES2139774T3 - Uso de una combinacion de antineoplastones en la preparacion de un medicamento para el tratamiento de la neurofibromatosis. - Google Patents

Uso de una combinacion de antineoplastones en la preparacion de un medicamento para el tratamiento de la neurofibromatosis.

Info

Publication number
ES2139774T3
ES2139774T3 ES95106669T ES95106669T ES2139774T3 ES 2139774 T3 ES2139774 T3 ES 2139774T3 ES 95106669 T ES95106669 T ES 95106669T ES 95106669 T ES95106669 T ES 95106669T ES 2139774 T3 ES2139774 T3 ES 2139774T3
Authority
ES
Spain
Prior art keywords
neurofibromatosis
combination
antineoplasts
preparation
treatment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES95106669T
Other languages
English (en)
Inventor
Stanislaw R Burzynski
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Application granted granted Critical
Publication of ES2139774T3 publication Critical patent/ES2139774T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group

Abstract

EL PRESENTE INVENTO PROPORCIONA METODOS PARA EL TRATAMIENTO DE LA NEUROFIBROMATOSIS EN HUMANOS MEDIANTE LA ADMINISTRACION DE COMPOSICIONES FARMACEUTICAS, A UN PACIENTE AFECTADO, QUE CONTIENEN UNA CANTIDAD EFECTIVA TERAPEUTICAMENTE DE UNA COMBINACION DE EN UN RATIO DE PESO QUE OSCILE DESDE 1:1 A ALREDEDOR DE 1:10 (A:B); EN EL QUE R ES OH, NH{SUB,2}, OW, O H; X ES H, F, CI, BR, I, OH, OW, NO{SUB,2} O NH{SUB,2}; Y ES H, F, CI, BR, O I; W ES O UN GRUPO ALIFATICO C{SUB,1}-C{SUB,2}; Z ES UN GRUPO ALIFATICO O AROMATICO DE C{SUB,1} AC{SUB,12}; X E Y PUEDEN AMBOS VARIAR EN EL COMPUESTO; O SALES FARMACEUTICAMENTE ACEPTABLES DE LOS MISMOS. PARTICULARMENTE SE HA DESCUBIERTO AQUI UNA COMPOSICION QUE CONTIENE UN RATIO 1:4 DE SALES DE SODIO DE ACIDO FENILACETICO Y DE FENILACETIGLUTAMINA, FORMULADAS EN AMBAS FORMAS ORAL Y PARENTERAL. TIPICAMENTE, AL PACIENTE SE LE ADMINISTRA LA COMPOSICION DE LA COMBINACION A PARTIR DE 1 A 20G/DIA DIVIDIDA EN DOSIS. DESPUES DE VARIOS MESES DE TRATAMIENTO LOS PACIENTES MUESTRAN UN SIGNIFICANTE DESCENSO EN EL NUMERO Y TAMAÑO DE LOS NODULOS.
ES95106669T 1994-05-04 1995-05-03 Uso de una combinacion de antineoplastones en la preparacion de un medicamento para el tratamiento de la neurofibromatosis. Expired - Lifetime ES2139774T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/237,772 US5391575A (en) 1994-05-04 1994-05-04 Method for treating neurofibromatosis

Publications (1)

Publication Number Publication Date
ES2139774T3 true ES2139774T3 (es) 2000-02-16

Family

ID=22895101

Family Applications (1)

Application Number Title Priority Date Filing Date
ES95106669T Expired - Lifetime ES2139774T3 (es) 1994-05-04 1995-05-03 Uso de una combinacion de antineoplastones en la preparacion de un medicamento para el tratamiento de la neurofibromatosis.

Country Status (8)

Country Link
US (1) US5391575A (es)
EP (1) EP0680756B1 (es)
AT (1) ATE183390T1 (es)
AU (1) AU683145B2 (es)
DE (1) DE69511453T2 (es)
ES (1) ES2139774T3 (es)
HK (1) HK1016408A1 (es)
ZA (1) ZA953500B (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5391575A (en) * 1994-05-04 1995-02-21 Burzynski; Stanislaw R. Method for treating neurofibromatosis
US6127419A (en) * 1998-11-23 2000-10-03 Burzynski; Stanislaw R. Phenylacetic acid compositions for treating or preventing atherosclerosis and restenosis
US6987131B1 (en) * 2000-06-26 2006-01-17 Burzynski Stanislaw R Phenylacetic acid compositions for treating or preventing hypercholesterolemia
WO2002018324A2 (en) 2000-08-29 2002-03-07 Nobex Corporation Immunoregulatory compounds, derivatives thereof and their use
US8048924B2 (en) * 2001-08-29 2011-11-01 Biocon Limited Methods and compositions employing 4-aminophenylacetic acid compounds
PL1773767T3 (pl) 2004-07-07 2016-07-29 Biocon Ltd Synteza azowo związanych związków immunoregulacyjnych
US20060205818A1 (en) * 2005-03-08 2006-09-14 Burzynski Stanislaw R Method for the treatment of von Hippel-Lindau (VHL) disease with phenylacetyl-derivatives

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4559325A (en) * 1981-12-15 1985-12-17 Burzynski Stanislaw R Purified antineoplaston fractions and methods of treating neoplastic disease
US5227292A (en) * 1990-07-12 1993-07-13 University Of Utah Neurofibromatosis type 1 gene
US5244922A (en) * 1990-09-04 1993-09-14 Burzynski Stanislaw R Methods for treating viral infections
US5116622A (en) * 1990-09-12 1992-05-26 Burzynski Stanislaw R Methods for treating parkinson's disease
US5391575A (en) * 1994-05-04 1995-02-21 Burzynski; Stanislaw R. Method for treating neurofibromatosis

Also Published As

Publication number Publication date
DE69511453D1 (de) 1999-09-23
US5391575A (en) 1995-02-21
EP0680756B1 (en) 1999-08-18
EP0680756A1 (en) 1995-11-08
ATE183390T1 (de) 1999-09-15
AU1777595A (en) 1995-11-09
HK1016408A1 (en) 1999-10-29
AU683145B2 (en) 1997-10-30
ZA953500B (en) 1996-05-29
DE69511453T2 (de) 1999-12-09

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