ES2138734T3 - Procedimiento para la preparacion de derivados de 1-(3-trialquilsililfenil)-2,2,2-trifluormetil etanona. - Google Patents

Procedimiento para la preparacion de derivados de 1-(3-trialquilsililfenil)-2,2,2-trifluormetil etanona.

Info

Publication number
ES2138734T3
ES2138734T3 ES95917074T ES95917074T ES2138734T3 ES 2138734 T3 ES2138734 T3 ES 2138734T3 ES 95917074 T ES95917074 T ES 95917074T ES 95917074 T ES95917074 T ES 95917074T ES 2138734 T3 ES2138734 T3 ES 2138734T3
Authority
ES
Spain
Prior art keywords
trialquilsililfenil
etanona
trifluormetil
derivatives
procedure
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES95917074T
Other languages
English (en)
Inventor
Richard A Wolf
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharmaceuticals Inc
Original Assignee
Merrell Dow Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharmaceuticals Inc filed Critical Merrell Dow Pharmaceuticals Inc
Application granted granted Critical
Publication of ES2138734T3 publication Critical patent/ES2138734T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/0803—Compounds with Si-C or Si-Si linkages
    • C07F7/0825—Preparations of compounds not comprising Si-Si or Si-cyano linkages
    • C07F7/083—Syntheses without formation of a Si-C bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

PROCESO PARA LA PREPARACION DE DERIVADOS 1-(3-TRIALQUILSILILFENIL)-2,2,2-TRIFLUOROMETIL ETANONAS, QUE SON UTILES PARA EL TRATAMIENTO DE LA ENFERMEDAD DE ALZHEIMER Y DE LA DEMENCIA SENIL, COMO LO DESCRIBEN SCHIRLIN Y COLABORADORES, EN LA PUBLICACION DE LA PATENTE EUROPEA NO. 0409676, PUBLICADA EL 23 DE ENERO DE 1991.
ES95917074T 1994-05-05 1995-04-18 Procedimiento para la preparacion de derivados de 1-(3-trialquilsililfenil)-2,2,2-trifluormetil etanona. Expired - Lifetime ES2138734T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US23876894A 1994-05-05 1994-05-05
US08/382,949 US5554780A (en) 1994-05-05 1995-02-01 Process for the preparation of 1-(3-trialkylsilylphenyl)-2,2,2-trifluoromethyl ethanone derivatives

Publications (1)

Publication Number Publication Date
ES2138734T3 true ES2138734T3 (es) 2000-01-16

Family

ID=26931932

Family Applications (1)

Application Number Title Priority Date Filing Date
ES95917074T Expired - Lifetime ES2138734T3 (es) 1994-05-05 1995-04-18 Procedimiento para la preparacion de derivados de 1-(3-trialquilsililfenil)-2,2,2-trifluormetil etanona.

Country Status (18)

Country Link
US (1) US5554780A (es)
EP (1) EP0758336B1 (es)
JP (1) JPH09512819A (es)
CN (1) CN1047176C (es)
AT (1) ATE182151T1 (es)
AU (1) AU681965B2 (es)
CA (1) CA2188761C (es)
DE (1) DE69510787T2 (es)
DK (1) DK0758336T3 (es)
ES (1) ES2138734T3 (es)
FI (1) FI964429A0 (es)
GR (1) GR3031283T3 (es)
HU (1) HU215133B (es)
IL (1) IL113605A (es)
NO (1) NO964652L (es)
NZ (1) NZ284696A (es)
TW (1) TW314521B (es)
WO (1) WO1995030678A1 (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0749972A1 (en) * 1995-06-21 1996-12-27 Merrell Pharmaceuticals Inc. A process for preparing 1-(3-trialkylsilylphenyl)-2,2,2-trifluoromethyl ethanone derivatives
US20100210590A1 (en) * 1995-09-27 2010-08-19 Northwestern University Compositions and treatments for seizure-related disorders
US20050222123A1 (en) 2004-01-27 2005-10-06 North Shore-Long Island Jewish Research Institute Cholinesterase inhibitors for treating inflammation
WO2006050359A2 (en) * 2004-11-02 2006-05-11 Northwestern University Pyridazine compounds and methods
CA2650711A1 (en) * 2006-04-28 2007-11-08 Northwestern University Compositions and treatments using pyridazine compounds and cholinesterase inhibitors
CN106045836B (zh) * 2016-06-30 2018-04-13 福州大学 一种铜催化合成芳烃或杂环三氟甲基酮的方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4536265A (en) * 1984-04-19 1985-08-20 Loctite Corporation Siloxane polyphotoinitiators of the substituted acetophenone type
SU1576526A1 (ru) * 1988-09-01 1990-07-07 Дальневосточный политехнический институт им.В.В.Куйбышева Способ получени N, N-диметиланилино- @ -трифторметилкетона
EP0403713A1 (en) * 1989-06-22 1990-12-27 Merrell Dow Pharmaceuticals Inc. Novel acetylcholinesterase inhibitors

Also Published As

Publication number Publication date
DK0758336T3 (da) 1999-11-29
ATE182151T1 (de) 1999-07-15
IL113605A (en) 1999-08-17
JPH09512819A (ja) 1997-12-22
HU9603050D0 (en) 1997-01-28
EP0758336B1 (en) 1999-07-14
HUT75866A (en) 1997-05-28
FI964429A (fi) 1996-11-04
WO1995030678A1 (en) 1995-11-16
CN1147256A (zh) 1997-04-09
NO964652D0 (no) 1996-11-04
EP0758336A1 (en) 1997-02-19
AU2390595A (en) 1995-11-29
TW314521B (es) 1997-09-01
HU215133B (hu) 1998-09-28
NO964652L (no) 1996-11-04
CA2188761A1 (en) 1995-11-16
CN1047176C (zh) 1999-12-08
US5554780A (en) 1996-09-10
GR3031283T3 (en) 1999-12-31
DE69510787D1 (de) 1999-08-19
CA2188761C (en) 1999-11-16
IL113605A0 (en) 1995-08-31
FI964429A0 (fi) 1996-11-04
DE69510787T2 (de) 1999-11-11
NZ284696A (en) 1997-12-19
AU681965B2 (en) 1997-09-11

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