ES2137896B1 - METHOD OF ANALYSIS OF TRANS-RESVERATROL BY LASER DESORPTION COUPLED RESONANT MULTIPHOTONIC AIONIZATION. - Google Patents

METHOD OF ANALYSIS OF TRANS-RESVERATROL BY LASER DESORPTION COUPLED RESONANT MULTIPHOTONIC AIONIZATION.

Info

Publication number
ES2137896B1
ES2137896B1 ES9800945A ES9800945A ES2137896B1 ES 2137896 B1 ES2137896 B1 ES 2137896B1 ES 9800945 A ES9800945 A ES 9800945A ES 9800945 A ES9800945 A ES 9800945A ES 2137896 B1 ES2137896 B1 ES 2137896B1
Authority
ES
Spain
Prior art keywords
analysis
resveratrol
trans
resonant
present
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
ES9800945A
Other languages
Spanish (es)
Other versions
ES2137896A1 (en
Inventor
Urena Angel Gonzalez
Rocha Jose Maria Orea
Catalina Carlos Montero
Del Castillo Belen Bescos
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Universidad Complutense de Madrid
Original Assignee
Universidad Complutense de Madrid
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Universidad Complutense de Madrid filed Critical Universidad Complutense de Madrid
Priority to ES9800945A priority Critical patent/ES2137896B1/en
Priority to PCT/ES1999/000118 priority patent/WO1999057748A1/en
Priority to AU35239/99A priority patent/AU3523999A/en
Publication of ES2137896A1 publication Critical patent/ES2137896A1/en
Application granted granted Critical
Publication of ES2137896B1 publication Critical patent/ES2137896B1/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/02—Details
    • H01J49/10—Ion sources; Ion guns
    • H01J49/16—Ion sources; Ion guns using surface ionisation, e.g. field-, thermionic- or photo-emission
    • H01J49/161—Ion sources; Ion guns using surface ionisation, e.g. field-, thermionic- or photo-emission using photoionisation, e.g. by laser
    • H01J49/162—Direct photo-ionisation, e.g. single photon or multi-photon ionisation

Landscapes

  • Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Engineering & Computer Science (AREA)
  • Plasma & Fusion (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Electron Tubes For Measurement (AREA)

Abstract

La presente invención se refiere a un método de análisis de trans-resveratrol por deserción láser acoplada a ionización multifotónica resonante. El método consta de tres etapas: - deserción por láser de las moléculas. - ionización multifotónica resonante de las moléculas desorbidas. - detección de los iones mediante espectrometría de masas por tiempo de vuelo. La ionización se debe realizar de forma sincronizada con la deserción y a la longitud de onda resonante de este compuesto, entre 302 y 307,5 nm. La presente invención se puede aplicar al análisis de trans-resveratrol tanto en muestras naturales como productos manufacturados, pudiéndose tratar en ambos casos de muestras sólidas o líquidas. Las distintas técnicas empleadas hasta el momento para el análisis de trans-resveratrol necesitan de largas y complejas operaciones de preparación de la muestra que dificultan y encarecen el proceso de análisis, siendo además una de las principales fuentes de error. La principal innovación del presente método es la realización de un análisis directo que permite aumentar la exactitud y precisión de las medidas facilitando de forma importante el proceso de análisis.The present invention refers to a method of analysis of trans-resveratrol by laser desertion coupled to resonant multiphoton ionization. The method consists of three stages: - laser desertion of the molecules. - resonant multiphoton ionization of the desorbed molecules. - detection of ions by mass spectrometry by time of flight. Ionization must be carried out in synchronization with the dropout and at the resonant wavelength of this compound, between 302 and 307.5 nm. The present invention can be applied to the analysis of trans-resveratrol in natural samples as well as manufactured products, being able to treat in both cases solid or liquid samples. The different techniques used to date for the analysis of trans-resveratrol require long and complex sample preparation operations that make the analysis process more difficult and expensive, and is also one of the main sources of error. The main innovation of the present method is the realization of a direct analysis that allows to increase the accuracy and precision of the measurements, greatly facilitating the analysis process.

ES9800945A 1998-05-05 1998-05-05 METHOD OF ANALYSIS OF TRANS-RESVERATROL BY LASER DESORPTION COUPLED RESONANT MULTIPHOTONIC AIONIZATION. Expired - Fee Related ES2137896B1 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
ES9800945A ES2137896B1 (en) 1998-05-05 1998-05-05 METHOD OF ANALYSIS OF TRANS-RESVERATROL BY LASER DESORPTION COUPLED RESONANT MULTIPHOTONIC AIONIZATION.
PCT/ES1999/000118 WO1999057748A1 (en) 1998-05-05 1999-05-05 Method for analyzing trans-resveratrol by laser desorption coupled to resonant multiphotonic ionization
AU35239/99A AU3523999A (en) 1998-05-05 1999-05-05 Method for analyzing trans-resveratrol by laser desorption coupled to resonant multiphotonic ionization

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES9800945A ES2137896B1 (en) 1998-05-05 1998-05-05 METHOD OF ANALYSIS OF TRANS-RESVERATROL BY LASER DESORPTION COUPLED RESONANT MULTIPHOTONIC AIONIZATION.

Publications (2)

Publication Number Publication Date
ES2137896A1 ES2137896A1 (en) 1999-12-16
ES2137896B1 true ES2137896B1 (en) 2000-08-16

Family

ID=8303689

Family Applications (1)

Application Number Title Priority Date Filing Date
ES9800945A Expired - Fee Related ES2137896B1 (en) 1998-05-05 1998-05-05 METHOD OF ANALYSIS OF TRANS-RESVERATROL BY LASER DESORPTION COUPLED RESONANT MULTIPHOTONIC AIONIZATION.

Country Status (3)

Country Link
AU (1) AU3523999A (en)
ES (1) ES2137896B1 (en)
WO (1) WO1999057748A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0803885D0 (en) * 2008-03-01 2008-04-09 Univ Belfast Improvements relating to mass spectrometry

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5045694A (en) * 1989-09-27 1991-09-03 The Rockefeller University Instrument and method for the laser desorption of ions in mass spectrometry
DE4036115C2 (en) * 1990-11-13 1997-12-11 Max Planck Gesellschaft Method and device for quantitative non-resonant photoionization of neutral particles and use of such a device
US5382793A (en) * 1992-03-06 1995-01-17 Hewlett-Packard Company Laser desorption ionization mass monitor (LDIM)
US5742050A (en) * 1996-09-30 1998-04-21 Aviv Amirav Method and apparatus for sample introduction into a mass spectrometer for improving a sample analysis
US5864137A (en) * 1996-10-01 1999-01-26 Genetrace Systems, Inc. Mass spectrometer

Also Published As

Publication number Publication date
AU3523999A (en) 1999-11-23
WO1999057748A1 (en) 1999-11-11
ES2137896A1 (en) 1999-12-16

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