ES2135490T3 - Aparato que mejora la fonoforesis intravascular, que comprende la disolucion de oclusiones intravasculares y la inhibicion concomitante de restenosis. - Google Patents

Aparato que mejora la fonoforesis intravascular, que comprende la disolucion de oclusiones intravasculares y la inhibicion concomitante de restenosis.

Info

Publication number
ES2135490T3
ES2135490T3 ES93921513T ES93921513T ES2135490T3 ES 2135490 T3 ES2135490 T3 ES 2135490T3 ES 93921513 T ES93921513 T ES 93921513T ES 93921513 T ES93921513 T ES 93921513T ES 2135490 T3 ES2135490 T3 ES 2135490T3
Authority
ES
Spain
Prior art keywords
intravascular
dissolution
phonophoresis
restenosis
radiator
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES93921513T
Other languages
English (en)
Inventor
Robert E Carter
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Coraje Inc
Original Assignee
Coraje Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/945,275 external-priority patent/US5318014A/en
Application filed by Coraje Inc filed Critical Coraje Inc
Application granted granted Critical
Publication of ES2135490T3 publication Critical patent/ES2135490T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/22Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
    • A61B17/22004Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for using mechanical vibrations, e.g. ultrasonic shock waves
    • A61B17/22012Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for using mechanical vibrations, e.g. ultrasonic shock waves in direct contact with, or very close to, the obstruction or concrement
    • A61B17/2202Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for using mechanical vibrations, e.g. ultrasonic shock waves in direct contact with, or very close to, the obstruction or concrement the ultrasound transducer being inside patient's body at the distal end of the catheter
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0092Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin using ultrasonic, sonic or infrasonic vibrations, e.g. phonophoresis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/22Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
    • A61B2017/22001Angioplasty, e.g. PCTA
    • A61B2017/22002Angioplasty, e.g. PCTA preventing restenosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/22Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
    • A61B17/22004Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for using mechanical vibrations, e.g. ultrasonic shock waves
    • A61B2017/22005Effects, e.g. on tissue
    • A61B2017/22007Cavitation or pseudocavitation, i.e. creation of gas bubbles generating a secondary shock wave when collapsing
    • A61B2017/22008Cavitation or pseudocavitation, i.e. creation of gas bubbles generating a secondary shock wave when collapsing used or promoted
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/22Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
    • A61B17/22004Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for using mechanical vibrations, e.g. ultrasonic shock waves
    • A61B17/22012Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for using mechanical vibrations, e.g. ultrasonic shock waves in direct contact with, or very close to, the obstruction or concrement
    • A61B17/2202Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for using mechanical vibrations, e.g. ultrasonic shock waves in direct contact with, or very close to, the obstruction or concrement the ultrasound transducer being inside patient's body at the distal end of the catheter
    • A61B2017/22021Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for using mechanical vibrations, e.g. ultrasonic shock waves in direct contact with, or very close to, the obstruction or concrement the ultrasound transducer being inside patient's body at the distal end of the catheter electric leads passing through the catheter
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/22Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
    • A61B2017/22082Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for after introduction of a substance

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Surgery (AREA)
  • Medical Informatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Dermatology (AREA)
  • Mechanical Engineering (AREA)
  • Anesthesiology (AREA)
  • Vascular Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Surgical Instruments (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
  • Materials For Medical Uses (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

UN APARATO ULTRASONICO (10) Y UN METODO PARA ACOPLAR UNA ENERGIA ULTRASONICA EN LAS PAREDES INTRAVASCULARES Y ASI AUMENTAR LA FONOFORESIS Y PARA LA DISOLUCION DE BLOQUEOS INTRAVASCULARES. EL APARATO (10) INCLUYE UN RADIADOR (44) PARA ACOPLAR ONDAS ULTRASONICAS Y UN CRISTAL PIEZOELECTRICO (24), CONECTADO A DICHO RADIADOR (44), PARA LA GENERACION INTRAVASCULAR DE ONDAS ULTRASONICAS; EN DONDE DICHAS ONDAS ULTRASONICAS SE PROPAGAN A LO LARGO DE UN EJE LONGITUDINAL (104) DE DICHO CRISTAL PIEZOELECTRICO (24). SE INTRODUCE UN LIQUIDO GERMINAL CERCA DEL RADIADOR PARA FOMENTAR LA CAVITACION DEL FLUIDO INTRAVASCULAR. ADEMAS SE AUMENTA SIGNIFICATIVAMENTE LA DISOLUCION DE LOS BLOQUEOS INTRAVASCULARES Y LA INHIBICION DE LA REESTENOSIS MEDIANTE AGENTES QUIMICOS CUANDO SE COMBINAN CON UNA ENERGIA ULTRASONICA.
ES93921513T 1992-09-14 1993-09-13 Aparato que mejora la fonoforesis intravascular, que comprende la disolucion de oclusiones intravasculares y la inhibicion concomitante de restenosis. Expired - Lifetime ES2135490T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/945,275 US5318014A (en) 1992-09-14 1992-09-14 Ultrasonic ablation/dissolution transducer
US08/058,222 US5362309A (en) 1992-09-14 1993-05-10 Apparatus and method for enhanced intravascular phonophoresis including dissolution of intravascular blockage and concomitant inhibition of restenosis

Publications (1)

Publication Number Publication Date
ES2135490T3 true ES2135490T3 (es) 1999-11-01

Family

ID=26737372

Family Applications (1)

Application Number Title Priority Date Filing Date
ES93921513T Expired - Lifetime ES2135490T3 (es) 1992-09-14 1993-09-13 Aparato que mejora la fonoforesis intravascular, que comprende la disolucion de oclusiones intravasculares y la inhibicion concomitante de restenosis.

Country Status (8)

Country Link
US (2) US5362309A (es)
EP (1) EP0664686B1 (es)
JP (1) JP3561274B2 (es)
AT (1) ATE182259T1 (es)
AU (1) AU4858093A (es)
DE (1) DE69325715T2 (es)
ES (1) ES2135490T3 (es)
WO (1) WO1994006355A1 (es)

Families Citing this family (178)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0504881B2 (en) * 1991-03-22 2000-11-08 Katsuro Tachibana Booster for therapy of diseases with ultrasound and pharmaceutical liquid composition containing the same
US5362309A (en) * 1992-09-14 1994-11-08 Coraje, Inc. Apparatus and method for enhanced intravascular phonophoresis including dissolution of intravascular blockage and concomitant inhibition of restenosis
US5509896A (en) * 1994-09-09 1996-04-23 Coraje, Inc. Enhancement of thrombolysis with external ultrasound
US5836940A (en) * 1994-10-25 1998-11-17 Latis, Inc. Photoacoustic drug delivery
US5683345A (en) * 1994-10-27 1997-11-04 Novoste Corporation Method and apparatus for treating a desired area in the vascular system of a patient
US6689086B1 (en) * 1994-10-27 2004-02-10 Advanced Cardiovascular Systems, Inc. Method of using a catheter for delivery of ultrasonic energy and medicament
US5899882A (en) 1994-10-27 1999-05-04 Novoste Corporation Catheter apparatus for radiation treatment of a desired area in the vascular system of a patient
US6210356B1 (en) 1998-08-05 2001-04-03 Ekos Corporation Ultrasound assembly for use with a catheter
US6176842B1 (en) 1995-03-08 2001-01-23 Ekos Corporation Ultrasound assembly for use with light activated drugs
DE69630285T2 (de) * 1995-03-08 2004-07-15 Ekos Corp., Bothell Ultraschalltherapievorrichtung
IL117560A0 (en) * 1995-03-30 1996-07-23 Res Dev Foundation Anti-stroke effects of calcium antagonists
WO1996034567A1 (en) * 1995-05-02 1996-11-07 Heart Rhythm Technologies, Inc. System for controlling the energy delivered to a patient for ablation
AU5739196A (en) * 1995-05-15 1996-11-29 Coraje, Inc. Enhancement of ultrasound thrombolysis
WO1997018851A1 (en) * 1995-11-24 1997-05-29 Ekos Corporation Hemostasis material and apparatus
US5725494A (en) * 1995-11-30 1998-03-10 Pharmasonics, Inc. Apparatus and methods for ultrasonically enhanced intraluminal therapy
US5735811A (en) 1995-11-30 1998-04-07 Pharmasonics, Inc. Apparatus and methods for ultrasonically enhanced fluid delivery
US5728062A (en) * 1995-11-30 1998-03-17 Pharmasonics, Inc. Apparatus and methods for vibratory intraluminal therapy employing magnetostrictive transducers
US5656016A (en) * 1996-03-18 1997-08-12 Abbott Laboratories Sonophoretic drug delivery system
US5971949A (en) * 1996-08-19 1999-10-26 Angiosonics Inc. Ultrasound transmission apparatus and method of using same
US5836896A (en) * 1996-08-19 1998-11-17 Angiosonics Method of inhibiting restenosis by applying ultrasonic energy
US6057367A (en) 1996-08-30 2000-05-02 Duke University Manipulating nitrosative stress to kill pathologic microbes, pathologic helminths and pathologically proliferating cells or to upregulate nitrosative stress defenses
US6024718A (en) * 1996-09-04 2000-02-15 The Regents Of The University Of California Intraluminal directed ultrasound delivery device
US5846218A (en) * 1996-09-05 1998-12-08 Pharmasonics, Inc. Balloon catheters having ultrasonically driven interface surfaces and methods for their use
US6464660B2 (en) 1996-09-05 2002-10-15 Pharmasonics, Inc. Balloon catheters having ultrasonically driven interface surfaces and methods for their use
US6024717A (en) * 1996-10-24 2000-02-15 Vibrx, Inc. Apparatus and method for sonically enhanced drug delivery
US6221038B1 (en) 1996-11-27 2001-04-24 Pharmasonics, Inc. Apparatus and methods for vibratory intraluminal therapy employing magnetostrictive transducers
US6676626B1 (en) 1998-05-01 2004-01-13 Ekos Corporation Ultrasound assembly with increased efficacy
US6582392B1 (en) 1998-05-01 2003-06-24 Ekos Corporation Ultrasound assembly for use with a catheter
US6723063B1 (en) * 1998-06-29 2004-04-20 Ekos Corporation Sheath for use with an ultrasound element
US6001069A (en) * 1997-05-01 1999-12-14 Ekos Corporation Ultrasound catheter for providing a therapeutic effect to a vessel of a body
AR012720A1 (es) 1997-05-19 2000-11-08 Angiosonics Inc Disposicion de control para una sonda acoplada a un transductor y metodo para controlar dicha sonda.
US6228046B1 (en) 1997-06-02 2001-05-08 Pharmasonics, Inc. Catheters comprising a plurality of oscillators and methods for their use
US5931805A (en) * 1997-06-02 1999-08-03 Pharmasonics, Inc. Catheters comprising bending transducers and methods for their use
JP4441000B2 (ja) * 1997-06-23 2010-03-24 克郎 立花 生体組織処理装置
EP1001708A1 (en) * 1997-08-07 2000-05-24 Cardiogenesis Corporation System and method of intra-operative myocardial revascularization using pulsed sonic energy
EP1043949A2 (en) 1997-12-31 2000-10-18 Pharmasonics, Inc. Methods and systems for the inhibition of vascular hyperplasia
CA2320300A1 (en) * 1998-02-10 1999-08-12 Angiosonics Inc. Apparatus and method for inhibiting restenosis by applying ultrasound energy together with drugs
US6312402B1 (en) 1998-09-24 2001-11-06 Ekos Corporation Ultrasound catheter for improving blood flow to the heart
US6135976A (en) * 1998-09-25 2000-10-24 Ekos Corporation Method, device and kit for performing gene therapy
AU1128600A (en) * 1998-11-20 2000-06-13 Joie P. Jones Methods for selectively dissolving and removing materials using ultra-high frequency ultrasound
US6620123B1 (en) * 1999-12-17 2003-09-16 Sontra Medical, Inc. Method and apparatus for producing homogenous cavitation to enhance transdermal transport
AU768190B2 (en) * 1998-12-18 2003-12-04 Sontra Medical, Inc. Method and apparatus for producing homogenous cavitation to enhance transdermal transport
US6309355B1 (en) 1998-12-22 2001-10-30 The Regents Of The University Of Michigan Method and assembly for performing ultrasound surgery using cavitation
US20050061335A1 (en) * 1999-01-07 2005-03-24 Morris Topaz Irrigation solution for use in ultrasound energy assisted surgery
ATE262891T1 (de) * 1999-01-07 2004-04-15 Moris Topaz Biokompatible injektierbare wässerige lösung zur verwendung bei ultraschallenergieunterstützter chirurgie
IL127967A (en) * 1999-01-07 2004-05-12 Moris Topaz Flushing solution for surgery using ultrasound energy
US8506519B2 (en) 1999-02-16 2013-08-13 Flowcardia, Inc. Pre-shaped therapeutic catheter
US6855123B2 (en) 2002-08-02 2005-02-15 Flow Cardia, Inc. Therapeutic ultrasound system
US6852097B1 (en) 1999-06-24 2005-02-08 Fulton, Iii Richard E. Mechanically active infusion catheter
US6361554B1 (en) 1999-06-30 2002-03-26 Pharmasonics, Inc. Methods and apparatus for the subcutaneous delivery of acoustic vibrations
US6387116B1 (en) 1999-06-30 2002-05-14 Pharmasonics, Inc. Methods and kits for the inhibition of hyperplasia in vascular fistulas and grafts
US20040097996A1 (en) 1999-10-05 2004-05-20 Omnisonics Medical Technologies, Inc. Apparatus and method of removing occlusions using an ultrasonic medical device operating in a transverse mode
US20050096669A1 (en) * 1999-10-05 2005-05-05 Omnisonics Medical Technologies, Inc. Apparatus and method for an ultrasonic medical device to treat coronary thrombus bearing lesions
US20030069525A1 (en) * 2000-03-08 2003-04-10 Pharmasonics, Inc. Methods, systems, and kits for plaque stabilization
US20040158317A1 (en) * 2000-07-18 2004-08-12 Pharmasonics, Inc. Coated stent with ultrasound therapy
US6416492B1 (en) 2000-09-28 2002-07-09 Scimed Life Systems, Inc. Radiation delivery system utilizing intravascular ultrasound
US6964647B1 (en) 2000-10-06 2005-11-15 Ellaz Babaev Nozzle for ultrasound wound treatment
US6487447B1 (en) 2000-10-17 2002-11-26 Ultra-Sonic Technologies, L.L.C. Method and apparatus for in-vivo transdermal and/or intradermal delivery of drugs by sonoporation
US6601581B1 (en) 2000-11-01 2003-08-05 Advanced Medical Applications, Inc. Method and device for ultrasound drug delivery
US6761729B2 (en) 2000-12-22 2004-07-13 Advanced Medicalapplications, Inc. Wound treatment method and device with combination of ultrasound and laser energy
US6533803B2 (en) 2000-12-22 2003-03-18 Advanced Medical Applications, Inc. Wound treatment method and device with combination of ultrasound and laser energy
US8235919B2 (en) 2001-01-12 2012-08-07 Celleration, Inc. Ultrasonic method and device for wound treatment
US7914470B2 (en) 2001-01-12 2011-03-29 Celleration, Inc. Ultrasonic method and device for wound treatment
US6960173B2 (en) 2001-01-30 2005-11-01 Eilaz Babaev Ultrasound wound treatment method and device using standing waves
DE10108799A1 (de) * 2001-02-19 2002-09-05 Laser & Med Tech Gmbh Verfahren und Vorrichtung zur Ultraschallimpfung von biologischem Zellmaterial
US6623444B2 (en) 2001-03-21 2003-09-23 Advanced Medical Applications, Inc. Ultrasonic catheter drug delivery method and device
US6478754B1 (en) 2001-04-23 2002-11-12 Advanced Medical Applications, Inc. Ultrasonic method and device for wound treatment
US8123789B2 (en) * 2002-04-29 2012-02-28 Rohit Khanna Central nervous system cooling catheter
US20040019318A1 (en) * 2001-11-07 2004-01-29 Wilson Richard R. Ultrasound assembly for use with a catheter
ATE520362T1 (de) * 2001-12-03 2011-09-15 Ekos Corp Katheter mit mehreren ultraschall-abstrahlenden teilen
AU2002353016A1 (en) 2001-12-03 2003-06-17 Ekos Corporation Small vessel ultrasound catheter
US7141044B2 (en) * 2001-12-11 2006-11-28 Ekos Corporation Alternate site gene therapy
CA2468975A1 (en) 2001-12-14 2003-06-26 Ekos Corporation Blood flow reestablishment determination
US6958040B2 (en) * 2001-12-28 2005-10-25 Ekos Corporation Multi-resonant ultrasonic catheter
US20030144680A1 (en) * 2002-01-22 2003-07-31 Sontra Medical, Inc. Portable ultrasonic scalpel/cautery device
US20040068189A1 (en) * 2002-02-28 2004-04-08 Wilson Richard R. Ultrasound catheter with embedded conductors
DE10211886B4 (de) * 2002-03-18 2004-07-15 Dornier Medtech Gmbh Verfahren und Einrichtung zum Erzeugen bipolarer akustischer Impulse
US8226629B1 (en) 2002-04-01 2012-07-24 Ekos Corporation Ultrasonic catheter power control
DE10223196B4 (de) * 2002-05-24 2004-05-13 Dornier Medtech Systems Gmbh Verfahren und Einrichtung zum Transferieren von Molekülen in Zellen
JP2004000336A (ja) * 2002-05-31 2004-01-08 Olympus Corp 超音波処置装置
US9955994B2 (en) 2002-08-02 2018-05-01 Flowcardia, Inc. Ultrasound catheter having protective feature against breakage
US8133236B2 (en) 2006-11-07 2012-03-13 Flowcardia, Inc. Ultrasound catheter having protective feature against breakage
US7604608B2 (en) 2003-01-14 2009-10-20 Flowcardia, Inc. Ultrasound catheter and methods for making and using same
US7335180B2 (en) 2003-11-24 2008-02-26 Flowcardia, Inc. Steerable ultrasound catheter
US7137963B2 (en) 2002-08-26 2006-11-21 Flowcardia, Inc. Ultrasound catheter for disrupting blood vessel obstructions
US7220233B2 (en) 2003-04-08 2007-05-22 Flowcardia, Inc. Ultrasound catheter devices and methods
US6942677B2 (en) 2003-02-26 2005-09-13 Flowcardia, Inc. Ultrasound catheter apparatus
US6921371B2 (en) 2002-10-14 2005-07-26 Ekos Corporation Ultrasound radiating members for catheter
US7771372B2 (en) 2003-01-03 2010-08-10 Ekos Corporation Ultrasonic catheter with axial energy field
US8142457B2 (en) * 2003-03-26 2012-03-27 Boston Scientific Scimed, Inc. Percutaneous transluminal endarterectomy
WO2004093656A2 (en) 2003-04-22 2004-11-04 Ekos Corporation Ultrasound enhanced central venous catheter
US7758510B2 (en) 2003-09-19 2010-07-20 Flowcardia, Inc. Connector for securing ultrasound catheter to transducer
US20050137520A1 (en) * 2003-10-29 2005-06-23 Rule Peter R. Catheter with ultrasound-controllable porous membrane
US7201737B2 (en) * 2004-01-29 2007-04-10 Ekos Corporation Treatment of vascular occlusions using elevated temperatures
US9107590B2 (en) 2004-01-29 2015-08-18 Ekos Corporation Method and apparatus for detecting vascular conditions with a catheter
WO2005072391A2 (en) * 2004-01-29 2005-08-11 Ekos Corporation Small vessel ultrasound catheter
US7341569B2 (en) * 2004-01-30 2008-03-11 Ekos Corporation Treatment of vascular occlusions using ultrasonic energy and microbubbles
US7794414B2 (en) 2004-02-09 2010-09-14 Emigrant Bank, N.A. Apparatus and method for an ultrasonic medical device operating in torsional and transverse modes
US7540852B2 (en) 2004-08-26 2009-06-02 Flowcardia, Inc. Ultrasound catheter devices and methods
WO2006049600A1 (en) * 2004-10-28 2006-05-11 Omnisonics Medical Technologies, Inc. Apparatus and method for an ultrasonic medical device to treat coronary thrombus bearing lesions
US8364256B2 (en) * 2004-11-15 2013-01-29 Coraje, Inc. Method and apparatus of removal of intravascular blockages
DE602005019367D1 (de) 2004-12-15 2010-04-01 Dornier Medtech Systems Gmbh Verbesserte Zelltherapie und Gewebsregeneration mittels Stosswellen bei Patienten mit kardiovaskulären and neurologischen Krankheiten
US8221343B2 (en) 2005-01-20 2012-07-17 Flowcardia, Inc. Vibrational catheter devices and methods for making same
US20060264809A1 (en) * 2005-04-12 2006-11-23 Hansmann Douglas R Ultrasound catheter with cavitation promoting surface
US7645290B2 (en) * 2005-05-05 2010-01-12 Lucas Paul R Multi-functional thrombectomy device
US7713218B2 (en) 2005-06-23 2010-05-11 Celleration, Inc. Removable applicator nozzle for ultrasound wound therapy device
US7785277B2 (en) 2005-06-23 2010-08-31 Celleration, Inc. Removable applicator nozzle for ultrasound wound therapy device
US8057408B2 (en) 2005-09-22 2011-11-15 The Regents Of The University Of Michigan Pulsed cavitational ultrasound therapy
US10219815B2 (en) 2005-09-22 2019-03-05 The Regents Of The University Of Michigan Histotripsy for thrombolysis
US9282984B2 (en) 2006-04-05 2016-03-15 Flowcardia, Inc. Therapeutic ultrasound system
US20070265560A1 (en) 2006-04-24 2007-11-15 Ekos Corporation Ultrasound Therapy System
US20080154181A1 (en) * 2006-05-05 2008-06-26 Khanna Rohit K Central nervous system ultrasonic drain
US7431704B2 (en) * 2006-06-07 2008-10-07 Bacoustics, Llc Apparatus and method for the treatment of tissue with ultrasound energy by direct contact
US8562547B2 (en) 2006-06-07 2013-10-22 Eliaz Babaev Method for debriding wounds
US20080039727A1 (en) * 2006-08-08 2008-02-14 Eilaz Babaev Ablative Cardiac Catheter System
AU2007286660A1 (en) * 2006-08-25 2008-02-28 Eilaz Babaev Portable ultrasound device for the treatment of wounds
US8192363B2 (en) 2006-10-27 2012-06-05 Ekos Corporation Catheter with multiple ultrasound radiating members
US8246643B2 (en) 2006-11-07 2012-08-21 Flowcardia, Inc. Ultrasound catheter having improved distal end
US7842006B2 (en) * 2006-11-17 2010-11-30 Cfd Research Corporation Thrombectomy microcatheter
US8491521B2 (en) 2007-01-04 2013-07-23 Celleration, Inc. Removable multi-channel applicator nozzle
US10182833B2 (en) 2007-01-08 2019-01-22 Ekos Corporation Power parameters for ultrasonic catheter
PL2111261T3 (pl) 2007-01-08 2015-08-31 Ekos Corp Parametry mocy cewnika ultradźwiękowego
PL2170181T3 (pl) 2007-06-22 2014-08-29 Ekos Corp Sposób i aparat do leczenia wylewów wewnątrzczaszkowych
US8262645B2 (en) * 2007-11-21 2012-09-11 Actuated Medical, Inc. Devices for clearing blockages in in-situ artificial lumens
US10702293B2 (en) 2008-06-13 2020-07-07 Shockwave Medical, Inc. Two-stage method for treating calcified lesions within the wall of a blood vessel
JP5636363B2 (ja) 2008-06-13 2014-12-03 ディージェイティー、 エルエルシー 衝撃波バルーンカテーテル装置
DE102008054083A1 (de) * 2008-10-31 2010-05-12 Theuer, Axel E., Prof. Dr.-Ing. habil. Medizinische Vorrichtung zur Behandlung von Tumorgewebe
US8226566B2 (en) 2009-06-12 2012-07-24 Flowcardia, Inc. Device and method for vascular re-entry
ES2503140T3 (es) 2009-07-03 2014-10-06 Ekos Corporation Parámetros de potencia para catéter ultrasónico
EP2451422B1 (en) 2009-07-08 2016-10-12 Sanuwave, Inc. Usage of extracorporeal and intracorporeal pressure shock waves in medicine
US9061131B2 (en) 2009-08-17 2015-06-23 Histosonics, Inc. Disposable acoustic coupling medium container
JP5863654B2 (ja) 2009-08-26 2016-02-16 リージェンツ オブ ザ ユニバーシティー オブ ミシガン 治療および画像処理超音波変換器用のマイクロマニピュレータ制御アーム
WO2011028609A2 (en) 2009-08-26 2011-03-10 The Regents Of The University Of Michigan Devices and methods for using controlled bubble cloud cavitation in fractionating urinary stones
US8539813B2 (en) 2009-09-22 2013-09-24 The Regents Of The University Of Michigan Gel phantoms for testing cavitational ultrasound (histotripsy) transducers
US9375223B2 (en) 2009-10-06 2016-06-28 Cardioprolific Inc. Methods and devices for endovascular therapy
US11039845B2 (en) 2009-10-06 2021-06-22 Cardioprolific Inc. Methods and devices for endovascular therapy
US20110105960A1 (en) * 2009-10-06 2011-05-05 Wallace Michael P Ultrasound-enhanced Stenosis therapy
US20110237982A1 (en) * 2009-10-06 2011-09-29 Wallace Michael P Ultrasound-enhanced stenosis therapy
US20110082396A1 (en) * 2009-10-06 2011-04-07 Wallace Michael P Ultrasound-enhanced stenosis therapy
US20110082414A1 (en) * 2009-10-06 2011-04-07 Wallace Michael P Ultrasound-enhanced stenosis therapy
US20110082534A1 (en) * 2009-10-06 2011-04-07 Wallace Michael P Ultrasound-enhanced stenosis therapy
US8740835B2 (en) 2010-02-17 2014-06-03 Ekos Corporation Treatment of vascular occlusions using ultrasonic energy and microbubbles
CN103228224B (zh) 2010-08-27 2015-11-25 Ekos公司 用于治疗颅内出血的方法和设备
US11458290B2 (en) 2011-05-11 2022-10-04 Ekos Corporation Ultrasound system
US9144694B2 (en) 2011-08-10 2015-09-29 The Regents Of The University Of Michigan Lesion generation through bone using histotripsy therapy without aberration correction
US9603615B2 (en) 2012-01-18 2017-03-28 C.R. Bard, Inc. Vascular re-entry device
US9049783B2 (en) 2012-04-13 2015-06-02 Histosonics, Inc. Systems and methods for obtaining large creepage isolation on printed circuit boards
JP2015516233A (ja) 2012-04-30 2015-06-11 ザ リージェンツ オブ ザ ユニバーシティ オブ ミシガン ラピッドプロトタイピング方法を使用した超音波トランスデューサー製造
US9642673B2 (en) 2012-06-27 2017-05-09 Shockwave Medical, Inc. Shock wave balloon catheter with multiple shock wave sources
JP6293145B2 (ja) 2012-08-02 2018-03-14 バード・ペリフェラル・バスキュラー・インコーポレーテッド 超音波カテーテルシステム
JP6257625B2 (ja) 2012-08-06 2018-01-10 ショックウェーブ メディカル, インコーポレイテッド 血管形成術用衝撃波カテーテルのための薄型電極
US9138249B2 (en) * 2012-08-17 2015-09-22 Shockwave Medical, Inc. Shock wave catheter system with arc preconditioning
US9333000B2 (en) 2012-09-13 2016-05-10 Shockwave Medical, Inc. Shockwave catheter system with energy control
US9522012B2 (en) 2012-09-13 2016-12-20 Shockwave Medical, Inc. Shockwave catheter system with energy control
WO2014055906A1 (en) 2012-10-05 2014-04-10 The Regents Of The University Of Michigan Bubble-induced color doppler feedback during histotripsy
SG11201506154RA (en) 2013-03-14 2015-09-29 Ekos Corp Method and apparatus for drug delivery to a target site
EP3016594B1 (en) 2013-07-03 2023-01-25 Histosonics, Inc. Histotripsy excitation sequences optimized for bubble cloud formation using shock scattering
US11432900B2 (en) 2013-07-03 2022-09-06 Histosonics, Inc. Articulating arm limiter for cavitational ultrasound therapy system
US10780298B2 (en) 2013-08-22 2020-09-22 The Regents Of The University Of Michigan Histotripsy using very short monopolar ultrasound pulses
WO2015080901A1 (en) 2013-11-26 2015-06-04 Celleration Inc. Systems and methods for producing and delivering ultrasonic therapies for wound treatment and healing
US10092742B2 (en) 2014-09-22 2018-10-09 Ekos Corporation Catheter system
WO2016201136A1 (en) 2015-06-10 2016-12-15 Ekos Corporation Ultrasound catheter
EP4230262A3 (en) 2015-06-24 2023-11-22 The Regents Of The University Of Michigan Histotripsy therapy systems for the treatment of brain tissue
WO2017087195A1 (en) 2015-11-18 2017-05-26 Shockwave Medical, Inc. Shock wave electrodes
US10226265B2 (en) 2016-04-25 2019-03-12 Shockwave Medical, Inc. Shock wave device with polarity switching
US20180140321A1 (en) 2016-11-23 2018-05-24 C. R. Bard, Inc. Catheter With Retractable Sheath And Methods Thereof
US10357264B2 (en) 2016-12-06 2019-07-23 Shockwave Medical, Inc. Shock wave balloon catheter with insertable electrodes
US11596726B2 (en) 2016-12-17 2023-03-07 C.R. Bard, Inc. Ultrasound devices for removing clots from catheters and related methods
US10758256B2 (en) 2016-12-22 2020-09-01 C. R. Bard, Inc. Ultrasonic endovascular catheter
US10582983B2 (en) 2017-02-06 2020-03-10 C. R. Bard, Inc. Ultrasonic endovascular catheter with a controllable sheath
US11020135B1 (en) 2017-04-25 2021-06-01 Shockwave Medical, Inc. Shock wave device for treating vascular plaques
US10966737B2 (en) 2017-06-19 2021-04-06 Shockwave Medical, Inc. Device and method for generating forward directed shock waves
US10709462B2 (en) 2017-11-17 2020-07-14 Shockwave Medical, Inc. Low profile electrodes for a shock wave catheter
EP3809988B1 (en) 2018-06-21 2023-06-07 Shockwave Medical, Inc. System for treating occlusions in body lumens
CN109200458A (zh) * 2018-11-13 2019-01-15 深圳市德迈科技有限公司 一种基于声孔效应的医用超声辅助给药设备及流程
CA3120586A1 (en) 2018-11-28 2020-06-04 Histosonics, Inc. Histotripsy systems and methods
US11478261B2 (en) 2019-09-24 2022-10-25 Shockwave Medical, Inc. System for treating thrombus in body lumens
US11813485B2 (en) 2020-01-28 2023-11-14 The Regents Of The University Of Michigan Systems and methods for histotripsy immunosensitization

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3141641A1 (de) * 1981-10-16 1983-04-28 Schering Ag, 1000 Berlin Und 4619 Bergkamen Ultraschall-kontrastmittel und dessen herstellung
WO1986005990A1 (en) * 1985-04-09 1986-10-23 Harvey Wolinsky Method for the prevention of restenosis
US4750902A (en) * 1985-08-28 1988-06-14 Sonomed Technology, Inc. Endoscopic ultrasonic aspirators
EP0293472B1 (en) * 1986-11-27 1994-04-13 Sumitomo Bakelite Company Limited Ultrasonic surgical apparatus
US4870953A (en) * 1987-11-13 1989-10-03 Donmicheal T Anthony Intravascular ultrasonic catheter/probe and method for treating intravascular blockage
US5040537A (en) * 1987-11-24 1991-08-20 Hitachi, Ltd. Method and apparatus for the measurement and medical treatment using an ultrasonic wave
DE3808783A1 (de) * 1988-03-16 1989-10-05 Dornier Medizintechnik Steinzerkleinerung durch kombinierte behandlung
FR2643252B1 (fr) * 1989-02-21 1991-06-07 Technomed Int Sa Appareil de destruction selective de cellules incluant les tissus mous et les os a l'interieur du corps d'un etre vivant par implosion de bulles de gaz
DE3930600A1 (de) * 1989-09-07 1991-04-04 Schubert Werner Dilitationssonde und aehnliche/zusaetzliche vorrichtungen
US5069664A (en) * 1990-01-25 1991-12-03 Inter Therapy, Inc. Intravascular ultrasonic angioplasty probe
US5197946A (en) * 1990-06-27 1993-03-30 Shunro Tachibana Injection instrument with ultrasonic oscillating element
US5269291A (en) * 1990-12-10 1993-12-14 Coraje, Inc. Miniature ultrasonic transducer for plaque ablation
US5362309A (en) * 1992-09-14 1994-11-08 Coraje, Inc. Apparatus and method for enhanced intravascular phonophoresis including dissolution of intravascular blockage and concomitant inhibition of restenosis

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AU4858093A (en) 1994-04-12
JP3561274B2 (ja) 2004-09-02
DE69325715D1 (de) 1999-08-26
EP0664686A1 (en) 1995-08-02
DE69325715T2 (de) 2000-02-17
US5474531A (en) 1995-12-12
EP0664686B1 (en) 1999-07-21
US5362309A (en) 1994-11-08
JPH08501238A (ja) 1996-02-13
WO1994006355A1 (en) 1994-03-31
ATE182259T1 (de) 1999-08-15

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