ES2124176B1 - Procedimiento para la obtencion de proteinas inactivadoras de ribosomas, denominadas beetin 27 y beetin 29, de las hojas de beta vulgaris (remolacha azucarera) infectadas con el virus de la amarillez. - Google Patents
Procedimiento para la obtencion de proteinas inactivadoras de ribosomas, denominadas beetin 27 y beetin 29, de las hojas de beta vulgaris (remolacha azucarera) infectadas con el virus de la amarillez.Info
- Publication number
- ES2124176B1 ES2124176B1 ES9602233A ES9602233A ES2124176B1 ES 2124176 B1 ES2124176 B1 ES 2124176B1 ES 9602233 A ES9602233 A ES 9602233A ES 9602233 A ES9602233 A ES 9602233A ES 2124176 B1 ES2124176 B1 ES 2124176B1
- Authority
- ES
- Spain
- Prior art keywords
- beetin
- obtaining
- leaves
- procedure
- beta vulgaris
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Landscapes
- Peptides Or Proteins (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
Procedimiento para la obtención de proteínas inactivadoras de ribosomas, denominadas beetin 27 y beetin 29, de las hojas de Beta vulgaris (remolacha azucarera) infectadas con el virus de la amarillez. Se describe un procedimiento de obtención de dos proteínas inactivadoras de ribosomas denominadas beetins 27 y 29 de la planta Beta vulgaris a partir de un extracto obtenido del líquido intercelular de las hojas de Beta vulgaris infectadas con virus y no a partir de un extracto de la planta total. El procedimiento general para la obtención de las beetins de la presente invención, incluye las etapas que se indican a continuación: a) Obtención del extracto del líquido intercelular de hojas de dicha planta. b) Diálisis y desarrollo de una cromatografía de intercambio iónico de la proteína obtenida en la etapa anterior con un gradiente de sal. c) Cromatografía de exclusión molecular de los picos de proteína de la etapa anterior. Dichas proteínas tiene aplicación como inhibidoras de la biosíntesisde proteínas y como inactivadoras del ácido ribonucleico genómico del virus y tienen utilidad en la terapia del cáncer y del SIDA y de enfermedades víricas de las plantas.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES9602233A ES2124176B1 (es) | 1996-10-07 | 1996-10-07 | Procedimiento para la obtencion de proteinas inactivadoras de ribosomas, denominadas beetin 27 y beetin 29, de las hojas de beta vulgaris (remolacha azucarera) infectadas con el virus de la amarillez. |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES9602233A ES2124176B1 (es) | 1996-10-07 | 1996-10-07 | Procedimiento para la obtencion de proteinas inactivadoras de ribosomas, denominadas beetin 27 y beetin 29, de las hojas de beta vulgaris (remolacha azucarera) infectadas con el virus de la amarillez. |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES2124176A1 ES2124176A1 (es) | 1999-01-16 |
| ES2124176B1 true ES2124176B1 (es) | 1999-10-01 |
Family
ID=8296449
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES9602233A Expired - Fee Related ES2124176B1 (es) | 1996-10-07 | 1996-10-07 | Procedimiento para la obtencion de proteinas inactivadoras de ribosomas, denominadas beetin 27 y beetin 29, de las hojas de beta vulgaris (remolacha azucarera) infectadas con el virus de la amarillez. |
Country Status (1)
| Country | Link |
|---|---|
| ES (1) | ES2124176B1 (es) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MXPA01001445A (es) | 1998-08-11 | 2002-11-29 | Large Scale Biology Corp | Metodo para recuperar proteinas a partir del fluido intersticial de tejidos de plantas. |
-
1996
- 1996-10-07 ES ES9602233A patent/ES2124176B1/es not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| ES2124176A1 (es) | 1999-01-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EC2A | Search report published |
Date of ref document: 19990116 Kind code of ref document: A1 Effective date: 19990116 |
|
| FD2A | Announcement of lapse in spain |
Effective date: 20170126 |