ES2121841T3 - Una vacuna para proporcionar proteccion inmunologica contra enfermedades de rotavirus en humanos. - Google Patents
Una vacuna para proporcionar proteccion inmunologica contra enfermedades de rotavirus en humanos.Info
- Publication number
- ES2121841T3 ES2121841T3 ES92900590T ES92900590T ES2121841T3 ES 2121841 T3 ES2121841 T3 ES 2121841T3 ES 92900590 T ES92900590 T ES 92900590T ES 92900590 T ES92900590 T ES 92900590T ES 2121841 T3 ES2121841 T3 ES 2121841T3
- Authority
- ES
- Spain
- Prior art keywords
- hrv
- human
- novel
- rotaviruses
- vaccine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/15—Reoviridae, e.g. calf diarrhea virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
- A61K2039/575—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 humoral response
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2720/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsRNA viruses
- C12N2720/00011—Details
- C12N2720/12011—Reoviridae
- C12N2720/12311—Rotavirus, e.g. rotavirus A
- C12N2720/12321—Viruses as such, e.g. new isolates, mutants or their genomic sequences
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2720/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsRNA viruses
- C12N2720/00011—Details
- C12N2720/12011—Reoviridae
- C12N2720/12311—Rotavirus, e.g. rotavirus A
- C12N2720/12334—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Virology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Mycology (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Abstract
SE PRESENTAN NUEVOS RETROVIRUS HUMANOS AISLADOS. LOS NUEVOS RETROVIRUS HUMANOS DE ACUERDO CON LA INVENCION TIENEN DERIVADOS SUS SEGMENTOS GENOMICOS A PARTIR DE LAS RAMAS PARENTERALES DE GENOGRUPOS Y/O SEROTIPOS. LOS RETROVIRUS DE LA INVENCION SE DESIGNAN COMO HRV 248, HRV 456, HRV 89-12C2, HRV 408 Y CJN. LOS RETROVIRUS DESIGNADOS COMO HRV 89-12C2, HRV 408, HRV 248 Y CJN HAN SIDO DEPOSITADOS CON LA "AMERICAN TYPE CULTURE COLLECTION" (ATCC), 12301 PARKLAWN DRIVE, ROCKVILLE, MD 20852, Y HAN SIDO ASIGNADOS A LOS SIGUIENTES NUMEROS DE LA ATCC VR 2272, VR 2273, VR 2274 Y VR 2275, RESPECTIVAMENTE. TAMBIEN SE HAN DESCUBIERTO NUEVAS VACUNAS FORMULADAS CON LOS RETROVIRUS HUMANOS DE LA INVENCION, Y METODOS DE VACUNACION DE LOS HUMANOS CONTRA LOS RETROVIRUS HUMANOS DE SEROTIPOS MULTIPLES CON TALES VACUNAS. TAMBIEN SE HA DESCUBIERTO UN NUEVO METODO DE NEUTRALIZACION DE ANTICUERPOS Y DE EXPANSION DE LA MEMORIA DE LAS CELULAS GENERADAS QUE EXPRESAN EL ANTICUERPO NEUTRALIZANTE FORMADO DESPUES DE LA VACUNACION PRIMARIA PARA EVITAR LAS ENFERMEDADES INDUCIDAS POR RETROVIRUS HUMANOS DE TODOS LOS SEROTIPOS, EL METODO COMPRENDE LA REVACUNACION DE LOS SUJETOS CON UNA VACUNA DE RETROVIRUS HETEROTIPICO ANIMAL NO HUMANO, TAL COMO CON UNA VACUNA DE WC3 BOBINO.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US61431090A | 1990-11-16 | 1990-11-16 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2121841T3 true ES2121841T3 (es) | 1998-12-16 |
Family
ID=24460695
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES92900590T Expired - Lifetime ES2121841T3 (es) | 1990-11-16 | 1991-11-04 | Una vacuna para proporcionar proteccion inmunologica contra enfermedades de rotavirus en humanos. |
Country Status (13)
Country | Link |
---|---|
US (2) | US5474773A (es) |
EP (1) | EP0557427B1 (es) |
JP (1) | JP2753393B2 (es) |
KR (1) | KR0171434B1 (es) |
AT (1) | ATE170081T1 (es) |
AU (2) | AU9060391A (es) |
BR (1) | BR9106982A (es) |
CA (1) | CA2096315C (es) |
DE (1) | DE69130068T2 (es) |
DK (1) | DK0557427T3 (es) |
ES (1) | ES2121841T3 (es) |
GR (1) | GR3027744T3 (es) |
WO (1) | WO1992008786A1 (es) |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5626851A (en) * | 1987-11-30 | 1997-05-06 | The Wistar Institute Of Anatomy And Biology | Rotavirus reassortant vaccine |
US5610049A (en) * | 1991-05-01 | 1997-03-11 | The Wistar Institute Of Anatomy And Biology | Human rotavirus HCR3A and method of growing said rotavirus |
US6780630B1 (en) * | 1992-07-10 | 2004-08-24 | Baylor College Of Medicine | Parenteral immunization against rotavirus |
US5773009A (en) * | 1994-04-15 | 1998-06-30 | The United States Of America As Represented By The Department Of Health And Human Services | Rotavirus strain G9P11 |
US7150984B2 (en) * | 1994-07-11 | 2006-12-19 | The United States Of America As Represented By The Department Of Health And Human Services | Attenuated human rotavirus vaccine |
US6673355B1 (en) | 1995-06-14 | 2004-01-06 | Baylor College Of Medicine | Rotavirus enterotoxin NSP4 and methods of using same |
AU6387196A (en) | 1995-06-14 | 1997-01-15 | Baylor College Of Medicine | Rotavirus enterotoxin nsp4 and methods of using same |
ID20581A (id) * | 1996-10-18 | 1999-01-21 | Res Fnd For Micbial Diseases O | Antigen rotavirus, vaksin dan agen diagnostik untuk infeksi rotavirus, serta metode untuk menghasilkan antigen |
US6589529B1 (en) | 1998-10-30 | 2003-07-08 | Children's Hospital Medical Center | Rotavirus subunit vaccine |
GB9919468D0 (en) | 1999-08-17 | 1999-10-20 | Smithkline Beecham Biolog | Vaccine |
DZ3219A1 (fr) * | 1999-08-17 | 2001-02-22 | Smithkline Beecham Biolog | Vaccin |
KR100305188B1 (ko) * | 2000-12-26 | 2001-09-24 | 정동혁 | 로타바이러스에 대한 백신 |
NZ545639A (en) * | 2003-09-02 | 2009-04-30 | Glaxosmithkline Biolog Sa | Cross-protective live attenuated human rotavirus vaccine |
GB0414787D0 (en) * | 2004-07-01 | 2004-08-04 | Glaxosmithkline Biolog Sa | Method |
CN100448485C (zh) * | 2003-09-02 | 2009-01-07 | 葛兰素史密丝克莱恩生物有限公司 | 疫苗 |
GB0503337D0 (en) | 2005-02-17 | 2005-03-23 | Glaxosmithkline Biolog Sa | Compositions |
US20090028828A1 (en) * | 2005-08-17 | 2009-01-29 | Glaxosmithkline Biologicals Sa | Rotavirus Vaccine Inducing Heterotypic Cross Protection |
ES2723776T3 (es) | 2009-05-12 | 2019-09-02 | The Government Of The Us Secretary Department Of Health And Human Services | Nuevas cepas de rotavirus humano y vacunas |
EP2847324B1 (en) | 2012-05-11 | 2018-01-03 | Medicago Inc. | Rotavirus-like particle production in plants |
CN107208072A (zh) | 2015-01-23 | 2017-09-26 | 莫迪卡戈公司 | 在植物中产生轮状病毒样颗粒 |
GB201614799D0 (en) | 2016-09-01 | 2016-10-19 | Glaxosmithkline Biologicals Sa | Compositions |
CN117737005B (zh) * | 2024-01-31 | 2024-05-14 | 金宇保灵生物药品有限公司 | 一株猪轮状病毒毒株及其应用 |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4341870A (en) * | 1980-11-19 | 1982-07-27 | The United States Of America As Represented By The Secretary Of The Department Of Health & Human Services | Cultivatable human rotavirus type 2 |
US4341763A (en) * | 1981-03-10 | 1982-07-27 | Smithkline-Rit | Methods of vaccinating humans against rotavirus infection |
US4571385A (en) * | 1983-06-27 | 1986-02-18 | The United States Of America As Represented By The Department Of Health And Human Services | Genetic reassortment of rotaviruses for production of vaccines and vaccine precursors |
US4624850A (en) * | 1984-02-09 | 1986-11-25 | Royal Children's Hospital Research Foundation | Live attenuated human rotavirus vaccine |
US4636385A (en) * | 1985-02-15 | 1987-01-13 | The Wistar Institute Of Anatomy & Biology | Vaccine, method for its preparation, and use thereof in vaccinating humans against rotavirus infection |
US4853333A (en) * | 1985-07-26 | 1989-08-01 | American Home Products Corporation | Production of rotavirus in yeast |
US4751080A (en) * | 1985-08-26 | 1988-06-14 | The United States Of America As Represented By The Department Of Health And Human Services | Vaccine against rotavirus diseases |
US4927628A (en) * | 1987-09-21 | 1990-05-22 | The United States Of America As Represented By The Department Of Health And Human Services | Vaccine against rotavirus diseases and method of preparing same |
WO1989006971A1 (en) * | 1988-02-01 | 1989-08-10 | The Board Of Trustees Of The Leland Stanford Junio | Conserved rotavirus gene segments and use in immunization and neutralization |
-
1991
- 1991-11-04 DK DK92900590T patent/DK0557427T3/da active
- 1991-11-04 AU AU90603/91A patent/AU9060391A/en not_active Abandoned
- 1991-11-04 EP EP92900590A patent/EP0557427B1/en not_active Expired - Lifetime
- 1991-11-04 DE DE69130068T patent/DE69130068T2/de not_active Expired - Lifetime
- 1991-11-04 AT AT92900590T patent/ATE170081T1/de not_active IP Right Cessation
- 1991-11-04 BR BR919106982A patent/BR9106982A/pt not_active Application Discontinuation
- 1991-11-04 CA CA002096315A patent/CA2096315C/en not_active Expired - Lifetime
- 1991-11-04 ES ES92900590T patent/ES2121841T3/es not_active Expired - Lifetime
- 1991-11-04 WO PCT/US1991/008191 patent/WO1992008786A1/en active IP Right Grant
- 1991-11-04 KR KR1019930701493A patent/KR0171434B1/ko not_active IP Right Cessation
- 1991-11-04 JP JP4501860A patent/JP2753393B2/ja not_active Expired - Lifetime
-
1993
- 1993-08-30 US US08/114,114 patent/US5474773A/en not_active Expired - Lifetime
-
1995
- 1995-06-05 US US08/465,210 patent/US5695767A/en not_active Expired - Lifetime
- 1995-11-15 AU AU37877/95A patent/AU702044B2/en not_active Expired
-
1998
- 1998-08-27 GR GR980401915T patent/GR3027744T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
KR0171434B1 (ko) | 1999-02-01 |
AU3787795A (en) | 1996-02-29 |
GR3027744T3 (en) | 1998-11-30 |
EP0557427B1 (en) | 1998-08-26 |
DE69130068T2 (de) | 1999-01-07 |
DK0557427T3 (da) | 1998-10-26 |
US5474773A (en) | 1995-12-12 |
CA2096315C (en) | 1996-11-19 |
AU9060391A (en) | 1992-06-11 |
JP2753393B2 (ja) | 1998-05-20 |
AU702044B2 (en) | 1999-02-11 |
BR9106982A (pt) | 1993-08-31 |
US5695767A (en) | 1997-12-09 |
EP0557427A1 (en) | 1993-09-01 |
JPH06505964A (ja) | 1994-07-07 |
EP0557427A4 (es) | 1995-01-25 |
DE69130068D1 (de) | 1998-10-01 |
WO1992008786A1 (en) | 1992-05-29 |
CA2096315A1 (fr) | 1992-05-17 |
ATE170081T1 (de) | 1998-09-15 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ES2121841T3 (es) | Una vacuna para proporcionar proteccion inmunologica contra enfermedades de rotavirus en humanos. | |
Barnard, BJH & Botha | An inactivated rift valley fever vaccine | |
Offit et al. | Rotavirus-specific cytotoxic T lymphocytes passively protect against gastroenteritis in suckling mice | |
US5462734A (en) | Bovine herpesvirus vaccine and method of using same | |
Fekadu et al. | Efficacy of rabies vaccines against Duvenhage virus isolated from European house bats (Eptesicus serotinus), classic rabies and rabies-related viruses | |
AU597603B2 (en) | Eimeria acervulina immunogens | |
EP0192404A3 (en) | Vaccine, method for its preparation and use thereof in vaccinating humans against rotavirus infection | |
DK0755259T3 (da) | Kimære-cDNA-kloner af virussen for den infektiöse GUMBORO-syge, ekspressionsprodukter heraf og vacciner baseret derpå | |
DK162171B (da) | Monoklonale antistoffer, der er reaktive med eimeriaarters sporozoitters antigener, og fremgangsmaade til deres fremstilling | |
Boone et al. | Tumour immunity induced in mice with cell-free homogenates of influenza virus-infected tumour cells | |
DE2967036D1 (en) | Vaccine and method of making | |
US5610059A (en) | Etiological agent for porcine enteritis | |
FI87530B (fi) | Foerfarande foer framstaellning av streptococcus equi -stammen | |
EP0498804A1 (en) | PROCESS FOR THE PREPARATION OF VACCINES OR TOXIC AGENTS AND FOR IMMUNIZATION AGAINST PATHOGENIC DISEASES. | |
Gao et al. | Truncated bovine herpesvirus-1 glycoprotein I (gpI) initiates a protective local immune response in its natural host | |
IL104382A0 (en) | Vaccine containing acemannan as an adjuvant | |
US3962422A (en) | Method for immunizing nursing piglets against transmissible gastroenteritis(TGE) virus | |
US5110589A (en) | Swine dysentery subunit vaccine and method | |
Nutter | Antigens of Pasteurella tularensis: preparative procedures | |
Ward | Human rotaviruses, vaccines and method | |
Yoo et al. | Maternal immunization of pregnant cattle with recombinant VP8* protein of bovine rotavirus elicits neutralizing antibodies to multiple serotypes: colostral neutralizing antibody by rotavirus VP8 | |
US4788059A (en) | Equine strangles vaccine and the method of preparing and using the same | |
Flores et al. | Molecular cloning of rotaviral genes: Implications for immunoprophylaxis. | |
JPH072650B2 (ja) | ロタウイルスワクチン | |
SU546132A1 (ru) | Способ профилактики гриппа |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
Ref document number: 557427 Country of ref document: ES |