ES2115644T3 - Procedimiento de preparacion de intermediarios de prostaglandinas. - Google Patents

Procedimiento de preparacion de intermediarios de prostaglandinas.

Info

Publication number
ES2115644T3
ES2115644T3 ES92307953T ES92307953T ES2115644T3 ES 2115644 T3 ES2115644 T3 ES 2115644T3 ES 92307953 T ES92307953 T ES 92307953T ES 92307953 T ES92307953 T ES 92307953T ES 2115644 T3 ES2115644 T3 ES 2115644T3
Authority
ES
Spain
Prior art keywords
isomer
prostaglandinas
intermediaries
preparing
procedure
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES92307953T
Other languages
English (en)
Inventor
Ryuji Ueno
Tomio Oda
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
R Tech Ueno Ltd
Original Assignee
R Tech Ueno Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by R Tech Ueno Ltd filed Critical R Tech Ueno Ltd
Application granted granted Critical
Publication of ES2115644T3 publication Critical patent/ES2115644T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/76—Unsaturated compounds containing keto groups
    • C07C59/90—Unsaturated compounds containing keto groups containing singly bound oxygen-containing groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
    • C07C69/738—Esters of keto-carboxylic acids or aldehydo-carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/94—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems condensed with rings other than six-membered or with ring systems containing such rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D317/30—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

EL INDICE ISOMERICO DE UN CIS-ISOMERO JUNTO AL TRANS-ISOMERO CORRESPONDIENTE CON RESPECTO AL ENLACE DOBLE 5 RADO EN LA PRODUCCION DE PROSTAGLANDINAS, CUANDO SE HACE REACCIONAR UN LACTOL CON UN ILIDO PARA PRODUCIR SIMULTANEAMENTE LA FORMACION DEL ENLACE DOBLE 5 Y UNA CADENA O, EN DONDE SE UTILIZAN EL ILIDO GENERADO A PARTIR DE UNA SAL DE FOSFONIO CON UNA BASE DE POTASIO, Y UN DISOLVENTE QUE ES UN LIQUIDO EN LA TEMPERATURA DE REACCION Y TIENE UN MOMENTO DIPOLAR DE 0,3 A 3,0D.
ES92307953T 1991-09-03 1992-09-02 Procedimiento de preparacion de intermediarios de prostaglandinas. Expired - Lifetime ES2115644T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP22270491 1991-09-03

Publications (1)

Publication Number Publication Date
ES2115644T3 true ES2115644T3 (es) 1998-07-01

Family

ID=16786602

Family Applications (1)

Application Number Title Priority Date Filing Date
ES92307953T Expired - Lifetime ES2115644T3 (es) 1991-09-03 1992-09-02 Procedimiento de preparacion de intermediarios de prostaglandinas.

Country Status (9)

Country Link
US (1) US5274130A (es)
EP (1) EP0532218B1 (es)
KR (1) KR0133050B1 (es)
AT (1) ATE164375T1 (es)
CA (1) CA2077418C (es)
DE (1) DE69224864T2 (es)
DK (1) DK0532218T3 (es)
ES (1) ES2115644T3 (es)
GR (1) GR3026452T3 (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60010913T2 (de) 1999-10-15 2005-06-09 Sucampo Ag Bizyklische Verbindungen, Zusammenstellung und Verfahren zu ihrer Stabilisierung
KR100423197B1 (ko) * 2001-09-07 2004-03-16 주식회사 강산푸드스터프 도토리로부터 전분 분리방법
TWI495471B (zh) * 2003-08-12 2015-08-11 R Tech Ueno Ltd 促進毛髮生長之組成物及方法
US20100041912A1 (en) * 2007-01-05 2010-02-18 Astra Zeneca Method for the wittig reaction in the preparation of carboprost

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3933898A (en) * 1972-10-30 1976-01-20 The Upjohn Company PGE1 -oxa phenylene compounds
US4259481A (en) * 1978-08-11 1981-03-31 The Upjohn Company 2-Decarboxy-2-hydroxymethyl-4-halo-5,9-epoxy-9-deoxy-PGF1 compounds
JPH0745504B2 (ja) * 1988-07-29 1995-05-17 株式会社上野製薬応用研究所 プロスタグランジン前駆体およびその製法

Also Published As

Publication number Publication date
CA2077418A1 (en) 1993-03-04
EP0532218B1 (en) 1998-03-25
KR930005996A (ko) 1993-04-20
DE69224864D1 (de) 1998-04-30
DE69224864T2 (de) 1998-07-23
KR0133050B1 (ko) 1998-04-17
DK0532218T3 (da) 1998-09-28
ATE164375T1 (de) 1998-04-15
GR3026452T3 (en) 1998-06-30
US5274130A (en) 1993-12-28
CA2077418C (en) 1996-12-10
EP0532218A1 (en) 1993-03-17

Similar Documents

Publication Publication Date Title
NO892626D0 (no) Fremgangsmaate for fremstilling av diorganodialkoxysilaner.
ATE141921T1 (de) Methode zur herstellung von alpha, beta ungesättigten ketolactonen
NO882277L (no) Fremgangsmaate for fremstilling av materialer som omfattermikrokapsler.
AU649230B2 (en) N-phenylpyrazole derivatives as insecticides
FR2333774A1 (fr) Harlocarboxylates substitues, utilisables comme intermediaires pour la fabrication d'insecticides pyrethroides
ES551337A0 (es) Metodo de preparar derivados de b-carbolin-3-oxadiazolilo
ES2052018T3 (es) Fabricacion de 1,1,1,2-tetrafluoroetano.
ES2115644T3 (es) Procedimiento de preparacion de intermediarios de prostaglandinas.
DK34287D0 (da) Tetrahydrocarbazol-l-alkansyre og farmaceutisk praeparat indeholdende en saadan forbindelse
AU588065B2 (en) Substituted diazaoxaspirodecanes, preparation thereof and use thereof as stabilizers for polymers
DK0619305T3 (da) Lactonforbindelse og fremgangsmåde til fremstilling deraf
EP0137289A3 (en) Process for the preparation of silica polymorphs from silicon
NO166177C (no) Analogifremgangsmaate til fremstilling av aminometyl-5,6,7,8-tetrahydronaftyloksyeddiksyrer.
NO901176L (no) Fremgangsmaate for fremstilling av 2,5,6,7-tetranor-4,8-inter-m-fenylen pgi2-derivater.
JPS5255480A (en) Production of semiconductor light emitting element
ATE94548T1 (de) Prostaglandin-vorlaeufer und ihre herstellung.
JPS57186136A (en) Semiconductor pressure transducer
AU6839790A (en) Derivatives and analogues of monoethylglycinexylidide and their production and use
IL83083A0 (en) Pyran derivatives,their production and their use as pesticides
DK460684D0 (da) 2,2-dichlor-(cis)-3-methyl-(trans)-3-chlor-methylcyclopropanmethanolog fremgangsmaade til fremstilling deraf
JPS5492912A (en) Preparation of monoterpenoid
JPS52131506A (en) Separation of citronellol
KR930010000A (ko) 피리딘 유도체의 제조방법
HUT48634A (en) Process for producing phosphorous-containing intermediates of herbicide compounds
JPS53144282A (en) Semiconductor type displacement converter and its manufacture

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 532218

Country of ref document: ES