DK0532218T3 - Fremgangsmåde til fremstilling af prostaglandinmellemprodukter - Google Patents
Fremgangsmåde til fremstilling af prostaglandinmellemprodukterInfo
- Publication number
- DK0532218T3 DK0532218T3 DK92307953T DK92307953T DK0532218T3 DK 0532218 T3 DK0532218 T3 DK 0532218T3 DK 92307953 T DK92307953 T DK 92307953T DK 92307953 T DK92307953 T DK 92307953T DK 0532218 T3 DK0532218 T3 DK 0532218T3
- Authority
- DK
- Denmark
- Prior art keywords
- isomer
- preparation
- double bond
- ylide
- prostaglandin intermediates
- Prior art date
Links
- 150000003180 prostaglandins Chemical class 0.000 title abstract 2
- 239000000543 intermediate Substances 0.000 title 1
- DYLIWHYUXAJDOJ-OWOJBTEDSA-N (e)-4-(6-aminopurin-9-yl)but-2-en-1-ol Chemical compound NC1=NC=NC2=C1N=CN2C\C=C\CO DYLIWHYUXAJDOJ-OWOJBTEDSA-N 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 239000007788 liquid Substances 0.000 abstract 1
- 229940094443 oxytocics prostaglandins Drugs 0.000 abstract 1
- 150000004714 phosphonium salts Chemical class 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/76—Unsaturated compounds containing keto groups
- C07C59/90—Unsaturated compounds containing keto groups containing singly bound oxygen-containing groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
- C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
- C07C69/738—Esters of keto-carboxylic acids or aldehydo-carboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
- C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/94—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems condensed with rings other than six-membered or with ring systems containing such rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
- C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D317/30—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP22270491 | 1991-09-03 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0532218T3 true DK0532218T3 (da) | 1998-09-28 |
Family
ID=16786602
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK92307953T DK0532218T3 (da) | 1991-09-03 | 1992-09-02 | Fremgangsmåde til fremstilling af prostaglandinmellemprodukter |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US5274130A (da) |
| EP (1) | EP0532218B1 (da) |
| KR (1) | KR0133050B1 (da) |
| AT (1) | ATE164375T1 (da) |
| CA (1) | CA2077418C (da) |
| DE (1) | DE69224864T2 (da) |
| DK (1) | DK0532218T3 (da) |
| ES (1) | ES2115644T3 (da) |
| GR (1) | GR3026452T3 (da) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AR026046A1 (es) | 1999-10-15 | 2002-12-26 | R Tech Ueno Ltd | NUEVA COMPOSICIoN Y MÉTODO PARA ESTABILIZAR LA MISMA |
| KR100423197B1 (ko) * | 2001-09-07 | 2004-03-16 | 주식회사 강산푸드스터프 | 도토리로부터 전분 분리방법 |
| TWI348386B (en) * | 2003-08-12 | 2011-09-11 | R Tech Ueno Ltd | Composition and method for promoting hair growth |
| US20100041912A1 (en) * | 2007-01-05 | 2010-02-18 | Astra Zeneca | Method for the wittig reaction in the preparation of carboprost |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3933898A (en) * | 1972-10-30 | 1976-01-20 | The Upjohn Company | PGE1 -oxa phenylene compounds |
| US4259481A (en) * | 1978-08-11 | 1981-03-31 | The Upjohn Company | 2-Decarboxy-2-hydroxymethyl-4-halo-5,9-epoxy-9-deoxy-PGF1 compounds |
| JPH0745504B2 (ja) * | 1988-07-29 | 1995-05-17 | 株式会社上野製薬応用研究所 | プロスタグランジン前駆体およびその製法 |
-
1992
- 1992-09-01 US US07/937,949 patent/US5274130A/en not_active Expired - Lifetime
- 1992-09-02 DK DK92307953T patent/DK0532218T3/da active
- 1992-09-02 DE DE69224864T patent/DE69224864T2/de not_active Expired - Fee Related
- 1992-09-02 AT AT92307953T patent/ATE164375T1/de not_active IP Right Cessation
- 1992-09-02 ES ES92307953T patent/ES2115644T3/es not_active Expired - Lifetime
- 1992-09-02 EP EP92307953A patent/EP0532218B1/en not_active Expired - Lifetime
- 1992-09-02 CA CA002077418A patent/CA2077418C/en not_active Expired - Fee Related
- 1992-09-03 KR KR1019920016050A patent/KR0133050B1/ko not_active IP Right Cessation
-
1998
- 1998-03-26 GR GR980400495T patent/GR3026452T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CA2077418A1 (en) | 1993-03-04 |
| ES2115644T3 (es) | 1998-07-01 |
| CA2077418C (en) | 1996-12-10 |
| ATE164375T1 (de) | 1998-04-15 |
| KR0133050B1 (ko) | 1998-04-17 |
| GR3026452T3 (en) | 1998-06-30 |
| KR930005996A (ko) | 1993-04-20 |
| DE69224864D1 (de) | 1998-04-30 |
| EP0532218B1 (en) | 1998-03-25 |
| DE69224864T2 (de) | 1998-07-23 |
| EP0532218A1 (en) | 1993-03-17 |
| US5274130A (en) | 1993-12-28 |
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