ES2114188T3 - Uso de antagonistas de los esteroides para el tratamiento y profilaxis de las enfermedades de demencia. - Google Patents

Uso de antagonistas de los esteroides para el tratamiento y profilaxis de las enfermedades de demencia.

Info

Publication number
ES2114188T3
ES2114188T3 ES94912437T ES94912437T ES2114188T3 ES 2114188 T3 ES2114188 T3 ES 2114188T3 ES 94912437 T ES94912437 T ES 94912437T ES 94912437 T ES94912437 T ES 94912437T ES 2114188 T3 ES2114188 T3 ES 2114188T3
Authority
ES
Spain
Prior art keywords
steroid
antagonists
receptor
prophylaxis
treatment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES94912437T
Other languages
English (en)
Spanish (es)
Inventor
Rainer Denecke
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Altramed Holdings Ltd
Original Assignee
Altramed Holdings Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Altramed Holdings Ltd filed Critical Altramed Holdings Ltd
Application granted granted Critical
Publication of ES2114188T3 publication Critical patent/ES2114188T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Steroid Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ES94912437T 1993-04-10 1994-03-30 Uso de antagonistas de los esteroides para el tratamiento y profilaxis de las enfermedades de demencia. Expired - Lifetime ES2114188T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4311870A DE4311870C2 (de) 1993-04-10 1993-04-10 Verwendung eines Anti-Östrigens zur Therapie und Prophylaxe von Demenz-Erkrankungen

Publications (1)

Publication Number Publication Date
ES2114188T3 true ES2114188T3 (es) 1998-05-16

Family

ID=6485255

Family Applications (1)

Application Number Title Priority Date Filing Date
ES94912437T Expired - Lifetime ES2114188T3 (es) 1993-04-10 1994-03-30 Uso de antagonistas de los esteroides para el tratamiento y profilaxis de las enfermedades de demencia.

Country Status (11)

Country Link
US (2) US6232350B1 (el)
EP (2) EP0692962B1 (el)
JP (1) JPH08508507A (el)
AT (1) ATE163543T1 (el)
AU (1) AU690110B2 (el)
CA (1) CA2160132C (el)
DE (2) DE4311870C2 (el)
DK (1) DK0692962T3 (el)
ES (1) ES2114188T3 (el)
GR (1) GR3026392T3 (el)
WO (1) WO1994023708A1 (el)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5552415A (en) * 1993-12-21 1996-09-03 Eli Lilly And Company Method of inhibiting Alzheimer's Disease
WO1995017095A1 (en) * 1993-12-21 1995-06-29 Eli Lilly And Company Methods for the treatment or prevention of conditions associated with amyloidogenic reptides
US6562862B1 (en) * 1994-10-20 2003-05-13 Eli Lilly And Company Methods of inhibiting physiological conditions associated with an excess of neuropeptide Y
CZ212097A3 (en) * 1995-01-20 1997-11-12 Novo Nordisk As Use of 3,4-diphenylchromans for preparing a medicament intended for treating or prophylaxis of cerebral degenerative diseases
CA2301032C (en) * 1997-08-15 2009-01-13 Duke University A method of preventing or treating estrogen-dependent diseases and disorders
GB9824207D0 (en) * 1998-11-04 1998-12-30 Zeneca Ltd Neurological disorders
AR027878A1 (es) * 1999-11-05 2003-04-16 Wyeth Corp Metodos para identificar y utilizar compuestos inhibidores de amiloides
US7067550B2 (en) * 2000-11-03 2006-06-27 Massachusetts Institute Of Technology Treatments for neurotoxicity in Alzheimer's Disease
WO2005105063A1 (en) * 2004-05-03 2005-11-10 Universita' Degli Studi Di Firenze Pharmaceutical compositions containing serms for the treatment of alzheimer's disease
AU2006226774B2 (en) 2005-03-24 2010-12-02 Emory University Methods for the treatment of central nervous system injury via a tapered administration of progesterone
US7473687B2 (en) 2005-03-24 2009-01-06 Emory University Methods for the treatment of a traumatic central nervous system injury

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3046719C2 (de) * 1980-12-11 1983-02-17 Klinge Pharma GmbH, 8000 München 1,1,2-Triphenyl-but-1-en-Derivate, Verfahren zu ihrer Herstellung und Arzneimittel
US5491173A (en) * 1982-06-25 1996-02-13 Orion-Yhtyma Oy Tri-phenyl alkene derivatives and their preparation and use
US4791099A (en) * 1984-10-29 1988-12-13 Chaovanee Aroonsakul Method of treatment for central nervous system diseases such as Alzheimer's's disease
ES2078890T3 (es) * 1986-10-09 1996-01-01 Upjohn Co Amino esteroides en c20 a c26.
GB9207437D0 (en) * 1992-04-03 1992-05-20 Orion Yhtymae Oy Topical administration of toremifene and its metabolites
DE69313106T2 (de) * 1992-05-01 1998-01-22 British Tech Group Substituierte 1,1,2,-triphenylbutene und ihre verwendung zur behandlung und diagnose von krebs
US5264619B1 (en) * 1993-01-15 1996-05-14 Cosmos Pharm Corp Anti-androgenic cyclo and bicyclo alkenes
US5552415A (en) * 1993-12-21 1996-09-03 Eli Lilly And Company Method of inhibiting Alzheimer's Disease
US5455275A (en) * 1994-05-11 1995-10-03 Eli Lilly And Company Methods for inhibiting endometriosis and uterine fibroid disease with 1,1,2-triphenylbut-1-ene derivatives
US5470883A (en) * 1994-05-23 1995-11-28 Stromberg; Brent V. Method of treating peripheral vasoconstriction with tamoxifen citrate
IL120269A0 (en) * 1996-02-28 1997-06-10 Pfizer 1,1,2-triphenylbut-1-ene derivatives for treating Alzheimer's disease

Also Published As

Publication number Publication date
AU690110B2 (en) 1998-04-23
GR3026392T3 (en) 1998-06-30
US6232350B1 (en) 2001-05-15
DE4311870A1 (de) 1994-10-13
DK0692962T3 (da) 1998-09-28
US20010018434A1 (en) 2001-08-30
CA2160132C (en) 2002-01-15
ATE163543T1 (de) 1998-03-15
DE59405394D1 (de) 1998-04-09
EP0692962A1 (de) 1996-01-24
DE4311870C2 (de) 1998-07-30
EP0797990A2 (de) 1997-10-01
AU6501494A (en) 1994-11-08
CA2160132A1 (en) 1994-10-27
WO1994023708A1 (de) 1994-10-27
EP0797990A3 (de) 1997-10-08
JPH08508507A (ja) 1996-09-10
EP0692962B1 (de) 1998-03-04

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