ES2108679T3 - Utilizacion de receptores monoclonales frente a oncoproteinas para vigilar terapias contra el cancer. - Google Patents
Utilizacion de receptores monoclonales frente a oncoproteinas para vigilar terapias contra el cancer.Info
- Publication number
- ES2108679T3 ES2108679T3 ES88310540T ES88310540T ES2108679T3 ES 2108679 T3 ES2108679 T3 ES 2108679T3 ES 88310540 T ES88310540 T ES 88310540T ES 88310540 T ES88310540 T ES 88310540T ES 2108679 T3 ES2108679 T3 ES 2108679T3
- Authority
- ES
- Spain
- Prior art keywords
- sample
- oncoproteins
- pattern
- against cancer
- therapies against
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/82—Translation products from oncogenes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/32—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products of oncogenes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56983—Viruses
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
- G01N33/57488—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites involving compounds identifable in body fluids
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Analytical Chemistry (AREA)
- Organic Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Food Science & Technology (AREA)
- Biophysics (AREA)
- Oncology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Virology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Hospice & Palliative Care (AREA)
- Gastroenterology & Hepatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Bioinformatics & Computational Biology (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
UN METODO DE DIAGNOSIS, POR EJEMPLO, PARA DETECTAR LA PRESENCIA O GRAVEDAD DEL CANCER, INCLUYE PONER EN CONTACTO UNA MUESTRA DEL CUERPO, POR EJEMPLO ORINA, CON DOS MOLECULAS RECEPTORAS DIFERENTES POR LO MENOS, PARA GENERAR UN PRIMER PATRON DE REACTIVIDAD. ESTE PATRON SE PUEDE GENERAR COMO MONOCLONAL QUE ENLAZA A POLIPEPTIDOS EN LA MUESTRA QUE SE CODIFICA POR ENCOGENES, Y LUEGO SE COMPARA CON UN SEGUNDO PATRON DE REACTIVIDAD GENERADO POR UNA MUESTRA BIOLOGICA CONOCIDA. ESTA MUESTRA CONOCIDA ES INDICATIVA DE LA EXPRESION ENCOGENE O SECUENCIAS RELACIONADAS CON ENCOGENES. TAMBIEN SE DESCRIBEN CONJUNTOS PARA DIAGNOSTICO QUE UTILIZAN ESTE METODO, DONDE LOS RESULTADOS SE PUEDEN INTERPRETAR MEDIANTE EXPLORADOR AUTOMATICO.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US11882387A | 1987-11-09 | 1987-11-09 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2108679T3 true ES2108679T3 (es) | 1998-01-01 |
Family
ID=22380954
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES88310540T Expired - Lifetime ES2108679T3 (es) | 1987-11-09 | 1988-11-09 | Utilizacion de receptores monoclonales frente a oncoproteinas para vigilar terapias contra el cancer. |
Country Status (10)
Country | Link |
---|---|
US (1) | US20030215894A1 (es) |
EP (1) | EP0318179B1 (es) |
JP (1) | JPH03500928A (es) |
AT (1) | ATE157172T1 (es) |
AU (2) | AU2497388A (es) |
CA (1) | CA1339069C (es) |
DE (1) | DE3856004T2 (es) |
ES (1) | ES2108679T3 (es) |
GR (1) | GR3025378T3 (es) |
WO (1) | WO1989004489A1 (es) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5733738A (en) * | 1983-08-17 | 1998-03-31 | Ligand Pharmaceuticals | Polypeptide-induced monoclonal receptors to protein ligands |
CA1219232A (en) * | 1983-08-17 | 1987-03-17 | Richard A. Lerner | Polypeptide-induced monoclonal receptors to protein ligands |
AU596670B2 (en) * | 1986-05-06 | 1990-05-10 | Amgen, Inc. | Assays and antibodies for n-myc proteins |
EP0354808B1 (en) * | 1988-08-12 | 1997-12-03 | Ligand Pharmaceuticals Incorporated | Polypeptide-induced monoclonal receptors to protein ligands |
GB9103974D0 (en) * | 1991-02-26 | 1991-04-10 | Norsk Hydro As | Therapeutically useful peptides or peptide fragments |
US7115728B1 (en) | 1995-01-30 | 2006-10-03 | Ligand Pharmaceutical Incorporated | Human peroxisome proliferator activated receptor γ |
US6489451B1 (en) | 1997-04-10 | 2002-12-03 | Hefei-Siu-Fung Ustc Pharmaceutical Co., Ltd. | Antithrombosis enzyme from the snake venom of agkistrodon acutus |
US7098025B1 (en) | 1997-07-25 | 2006-08-29 | Ligand Pharmaceuticals Incorporated | Human peroxisome proliferator activated receptor gamma (pparγ) gene regulatory sequences and uses therefor |
ATE393912T1 (de) * | 1998-02-04 | 2008-05-15 | Invitrogen Corp | Microarrays und ihre verwendungen |
DE69907155T2 (de) * | 1998-02-18 | 2004-02-05 | Theryte Ltd. | Krebsbehandlung |
HUE039085T2 (hu) | 2006-01-20 | 2018-12-28 | Cell Signaling Technology Inc | Transzlokáció és mutáns ROS kináz humán nem-kissejtes tüdõ karcinómában |
US8383799B2 (en) | 2006-01-20 | 2013-02-26 | Cell Signaling Technology, Inc. | Translocation and mutant ROS kinase in human non-small cell lung carcinoma |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4535058A (en) * | 1982-10-01 | 1985-08-13 | Massachusetts Institute Of Technology | Characterization of oncogenes and assays based thereon |
US4798787A (en) * | 1984-09-19 | 1989-01-17 | Cetus Corporation | Peptide antibodies and their use in detecting oncogene products |
EP0206065A3 (en) * | 1985-06-27 | 1989-04-19 | James R. Feramisco | Method of detecting oncogene and proto-oncogene related proteins in extracellular biological fluids |
-
1988
- 1988-11-08 CA CA000582501A patent/CA1339069C/en not_active Expired - Fee Related
- 1988-11-09 JP JP1500180A patent/JPH03500928A/ja active Pending
- 1988-11-09 AU AU24973/88A patent/AU2497388A/en not_active Abandoned
- 1988-11-09 WO PCT/US1988/003921 patent/WO1989004489A1/en unknown
- 1988-11-09 AT AT88310540T patent/ATE157172T1/de not_active IP Right Cessation
- 1988-11-09 EP EP88310540A patent/EP0318179B1/en not_active Expired - Lifetime
- 1988-11-09 DE DE3856004T patent/DE3856004T2/de not_active Expired - Fee Related
- 1988-11-09 ES ES88310540T patent/ES2108679T3/es not_active Expired - Lifetime
-
1992
- 1992-11-26 AU AU29677/92A patent/AU665591B2/en not_active Ceased
-
1997
- 1997-11-13 GR GR970403021T patent/GR3025378T3/el unknown
-
2003
- 2003-01-24 US US10/350,405 patent/US20030215894A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
AU2967792A (en) | 1993-02-11 |
EP0318179A2 (en) | 1989-05-31 |
GR3025378T3 (en) | 1998-02-27 |
AU2497388A (en) | 1989-05-11 |
ATE157172T1 (de) | 1997-09-15 |
DE3856004T2 (de) | 1997-12-18 |
AU665591B2 (en) | 1996-01-11 |
JPH03500928A (ja) | 1991-02-28 |
EP0318179B1 (en) | 1997-08-20 |
US20030215894A1 (en) | 2003-11-20 |
EP0318179A3 (en) | 1990-08-01 |
DE3856004D1 (de) | 1997-09-25 |
WO1989004489A1 (en) | 1989-05-18 |
CA1339069C (en) | 1997-07-29 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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