ES2106875T3 - Procedimiento para preparar sustancias farmacologicas en forma de perla. - Google Patents
Procedimiento para preparar sustancias farmacologicas en forma de perla.Info
- Publication number
- ES2106875T3 ES2106875T3 ES92913973T ES92913973T ES2106875T3 ES 2106875 T3 ES2106875 T3 ES 2106875T3 ES 92913973 T ES92913973 T ES 92913973T ES 92913973 T ES92913973 T ES 92913973T ES 2106875 T3 ES2106875 T3 ES 2106875T3
- Authority
- ES
- Spain
- Prior art keywords
- processing chamber
- particles
- drug
- spray
- coater
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2/00—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic
- B01J2/006—Coating of the granules without description of the process or the device by which the granules are obtained
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
- A61J3/005—Coating of tablets or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
- A61K9/1676—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface having a drug-free core with discrete complete coating layer containing drug
Landscapes
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Catalysts (AREA)
- Saccharide Compounds (AREA)
- Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
- Glanulating (AREA)
Abstract
SUBSTANCIAS MEDICINALES EN FORMA DE CUENTAS, SE PREPARAN CON UN REVESTIMIENTO POR PULVERIZACION DE ALTA DENSIDAD DE MASA SOBRE PARTICULAS DE NUCLEO INERTE, EMPLEANDO UN APARATO REVESTIDOR DE GRANULOS QUE COMPRENDE; LA FORMACION DE UN LECHO FLUIDIFICADO DE PARTICULAS DE MATERIAL DE NUCLEO INERTE DENTRO DE UNA CAMARA DE PROCESAMIENTO DE UN APARATO REVESTIDOR DE GRANULOS, PASANDO UNA CORRIENTE GASEOSA ENTRE EL DISCO ROTATORIO Y LA PARED INTERIOR DE LA CAMARA DE PROCESAMIENTO; Y FORMANDO CUENTAS DEPOSITANDO UN MEDICAMENTO SOBRE LAS PARTICULAS DEL MATERIAL DEL NUCLEO, MEDIANTE PULVERIZACION DEL REVESTIMIENTO CON UNA SOLUCION DEL MEDICAMENTO; CARACTERIZADA EN QUE DURANTE LA FORMACION DE LAS CUENTAS, LAS PARTICULAS DE REVESTIMIENTO PULVERIZADAS SON (I) TRANSPORTADAS A UNA ZONA DE SECADO QUE RODEA LA CAMARA DE PROCESAMIENTO, (II) EFECTUANDO EL SECADO EN LA ZONA POR MEDIO DE UNA CORRIENTE GASEOSA, Y (III) VOLVIENDO A LA CAMARA DE PROCESAMIENTO; CONTINUANDOSE EL PROCESO DE RECIRCULACION HASTA QUE LASCAPSULAS FORMADAS TIENEN LA CANTIDAD DE MEDICAMENTO DESEADA.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB919114374A GB9114374D0 (en) | 1991-07-03 | 1991-07-03 | Novel process |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2106875T3 true ES2106875T3 (es) | 1997-11-16 |
Family
ID=10697757
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES92913973T Expired - Lifetime ES2106875T3 (es) | 1991-07-03 | 1992-06-30 | Procedimiento para preparar sustancias farmacologicas en forma de perla. |
Country Status (15)
Country | Link |
---|---|
EP (1) | EP0593552B1 (es) |
JP (1) | JPH06508779A (es) |
KR (1) | KR100227999B1 (es) |
AT (1) | ATE157559T1 (es) |
AU (1) | AU659192B2 (es) |
CA (1) | CA2112743A1 (es) |
DE (1) | DE69222043T2 (es) |
DK (1) | DK0593552T3 (es) |
ES (1) | ES2106875T3 (es) |
GB (1) | GB9114374D0 (es) |
GR (1) | GR3025311T3 (es) |
HK (1) | HK1002628A1 (es) |
IE (1) | IE79672B1 (es) |
WO (1) | WO1993000991A1 (es) |
ZA (1) | ZA924882B (es) |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5425366A (en) * | 1988-02-05 | 1995-06-20 | Schering Aktiengesellschaft | Ultrasonic contrast agents for color Doppler imaging |
FR2737134B1 (fr) * | 1995-07-27 | 1998-05-29 | Bionatec Sarl | Procede de fabrication de granules et granules ainsi obtenus |
PT929294E (pt) * | 1996-04-04 | 2003-11-28 | Felix Specht | Processo para a preparacao de sistemas em po fluidos e/ou directamente compressiveis de baixa dosagem |
US5997905A (en) * | 1998-09-04 | 1999-12-07 | Mcneil-Ppc | Preparation of pharmaceutically active particles |
NZ510928A (en) | 1998-10-01 | 2002-10-25 | Powderject Res Ltd | Spray coated powder composition formed from seed particles between 10-100 micrometres coated with an aqueous pharmaceutical composition |
AU2002212102A1 (en) * | 2000-11-08 | 2002-05-21 | Aeromatic-Fielder Ag | A process for production of particles for pharmaceutical compositions having increased bioavailability |
SE0102511D0 (sv) | 2001-07-12 | 2001-07-12 | Astrazeneca Ab | Method and device for coating |
US8709476B2 (en) | 2003-11-04 | 2014-04-29 | Supernus Pharmaceuticals, Inc. | Compositions of quaternary ammonium compounds containing bioavailability enhancers |
WO2006095819A1 (ja) * | 2005-03-10 | 2006-09-14 | Taisho Pharmaceutical Co., Ltd. | 糖衣剤 |
US10357462B2 (en) | 2006-11-30 | 2019-07-23 | Ben Research, Inc. | Multiparticulates of spray-coated drug and polymer on a meltable core |
US11116728B2 (en) | 2006-11-30 | 2021-09-14 | Bend Research, Inc. | Multiparticulates of spray-coated drug and polymer on a meltable core |
US7908765B2 (en) * | 2006-12-22 | 2011-03-22 | Collette Nv | Continuous granulating and drying apparatus |
WO2011113855A2 (en) | 2010-03-17 | 2011-09-22 | Novaliq Gmbh | Pharmaceutical composition for treatment of increased intraocular pressure |
EP2444063A1 (en) | 2010-10-20 | 2012-04-25 | Novaliq GmbH | Liquid pharmaceutical compositions for the delivery of active ingredients |
KR102171897B1 (ko) | 2012-09-12 | 2020-11-02 | 노바리크 게엠베하 | 부분불소화 알칸 조성물 |
US10172882B2 (en) | 2014-06-22 | 2019-01-08 | Dexcel Pharma Technologies Ltd. | Pharmaceutical compositions comprising ferric citrate and methods for the production thereof |
DK3722274T3 (da) | 2015-09-30 | 2023-09-11 | Novaliq Gmbh | 2-perfluorbutylpentan til oftalmisk indgivelse |
CN111743882A (zh) | 2015-09-30 | 2020-10-09 | 诺瓦利克有限责任公司 | 半氟化化合物和其组合物 |
WO2017220625A1 (en) | 2016-06-23 | 2017-12-28 | Novaliq Gmbh | Topical administration method |
WO2018055101A1 (en) | 2016-09-23 | 2018-03-29 | Novaliq Gmbh | Ophthalmic compositions comprising ciclosporin |
KR102351816B1 (ko) | 2017-04-21 | 2022-01-17 | 노바리크 게엠베하 | 요오드 조성물 |
EP3621601A1 (en) | 2017-05-12 | 2020-03-18 | Novaliq GmbH | Pharmaceutical compositions comprosing semifluorinated alkanes for the treatment of contact lense-related conditions |
CN111372566A (zh) | 2017-09-27 | 2020-07-03 | 诺瓦利克有限责任公司 | 用于治疗眼部疾病的包含拉坦前列素的眼科用组合物 |
US11896559B2 (en) | 2017-10-04 | 2024-02-13 | Novaliq Gmbh | Opthalmic compositions comprising F6H8 |
CA3112031A1 (en) | 2018-10-12 | 2020-04-16 | Novaliq Gmbh | Ophthalmic composition for treatment of dry eye disease |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3408746A (en) * | 1967-03-13 | 1968-11-05 | Dow Chemical Co | Apparatus and method for recovering solids |
CH666828A5 (de) * | 1985-12-30 | 1988-08-31 | Aeromatic Ag | Vorrichtung zum herstellen und/oder bearbeiten von granulaten. |
EP0282514B1 (de) * | 1986-09-09 | 1990-04-18 | Pharmatronic AG | Verfahren und einrichtung zum agglomerieren von teilchen und/oder zum überziehen von solchen |
CA1338596C (en) * | 1988-09-27 | 1996-09-17 | Hiroyoshi Koyama | Granules having core and their production |
IL94169A0 (en) * | 1989-04-24 | 1991-01-31 | Du Pont | Pan granulation |
-
1991
- 1991-07-03 GB GB919114374A patent/GB9114374D0/en active Pending
-
1992
- 1992-06-30 EP EP92913973A patent/EP0593552B1/en not_active Expired - Lifetime
- 1992-06-30 ES ES92913973T patent/ES2106875T3/es not_active Expired - Lifetime
- 1992-06-30 WO PCT/GB1992/001185 patent/WO1993000991A1/en active IP Right Grant
- 1992-06-30 AT AT92913973T patent/ATE157559T1/de not_active IP Right Cessation
- 1992-06-30 JP JP5502062A patent/JPH06508779A/ja active Pending
- 1992-06-30 DK DK92913973.1T patent/DK0593552T3/da active
- 1992-06-30 KR KR1019930704122A patent/KR100227999B1/ko not_active IP Right Cessation
- 1992-06-30 AU AU21664/92A patent/AU659192B2/en not_active Ceased
- 1992-06-30 CA CA002112743A patent/CA2112743A1/en not_active Abandoned
- 1992-06-30 DE DE69222043T patent/DE69222043T2/de not_active Expired - Fee Related
- 1992-07-01 ZA ZA924882A patent/ZA924882B/xx unknown
- 1992-07-02 IE IE922165A patent/IE79672B1/en not_active IP Right Cessation
-
1997
- 1997-11-07 GR GR970402953T patent/GR3025311T3/el unknown
-
1998
- 1998-03-03 HK HK98101668A patent/HK1002628A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
HK1002628A1 (en) | 1998-09-04 |
GB9114374D0 (en) | 1991-08-21 |
EP0593552A1 (en) | 1994-04-27 |
DE69222043T2 (de) | 1998-02-05 |
GR3025311T3 (en) | 1998-02-27 |
KR940701297A (ko) | 1994-05-28 |
ZA924882B (en) | 1993-05-27 |
KR100227999B1 (ko) | 1999-11-01 |
ATE157559T1 (de) | 1997-09-15 |
DE69222043D1 (de) | 1997-10-09 |
DK0593552T3 (da) | 1997-10-27 |
EP0593552B1 (en) | 1997-09-03 |
IE922165A1 (en) | 1993-01-13 |
JPH06508779A (ja) | 1994-10-06 |
CA2112743A1 (en) | 1993-01-21 |
IE79672B1 (en) | 1998-05-20 |
WO1993000991A1 (en) | 1993-01-21 |
AU2166492A (en) | 1993-02-11 |
AU659192B2 (en) | 1995-05-11 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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