ES2106179T3 - Proteinas vehiculares desnaturalizadas para mejorar los ensayos inmunosorbentes ligados por enzimas. - Google Patents

Proteinas vehiculares desnaturalizadas para mejorar los ensayos inmunosorbentes ligados por enzimas.

Info

Publication number
ES2106179T3
ES2106179T3 ES92908459T ES92908459T ES2106179T3 ES 2106179 T3 ES2106179 T3 ES 2106179T3 ES 92908459 T ES92908459 T ES 92908459T ES 92908459 T ES92908459 T ES 92908459T ES 2106179 T3 ES2106179 T3 ES 2106179T3
Authority
ES
Spain
Prior art keywords
denaturalized
enzymes
improve
vehicular
specific binding
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES92908459T
Other languages
English (en)
Inventor
Chander P Bahl
Eleanor Batsko
Mitchell Nelles
Gerard Garcia
David Chien
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis Vaccines and Diagnostics Inc
Ortho Clinical Diagnostics Inc
Original Assignee
Ortho Diagnostic Systems Inc
Chiron Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ortho Diagnostic Systems Inc, Chiron Corp filed Critical Ortho Diagnostic Systems Inc
Application granted granted Critical
Publication of ES2106179T3 publication Critical patent/ES2106179T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/576—Immunoassay; Biospecific binding assay; Materials therefor for hepatitis
    • G01N33/5767—Immunoassay; Biospecific binding assay; Materials therefor for hepatitis non-A, non-B hepatitis
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54306—Solid-phase reaction mechanisms
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56983—Viruses
    • G01N33/56988—HIV or HTLV

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Microbiology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • AIDS & HIV (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

LA PRESENTE INVENCION SE REFIERE A METODOS DE INMUNOENSAYOS ENLAZADOS DE ENZIMA QUE USAN UNA PROTEINA DE FUSION COMO MIEMBRO DEL PAR DE UNION ESPECIFICA DE LA CONTRAPARTIDA DE UNION A MEDIR. LA PROTEINA DE FUSION CONTIENE UN COMPONENTE ESPECIFICO DE UNION Y UN COMPONENTE VEHICULAR. LA INTERACCION NO ESPECIFICA ENTRE EL COMPAÑERO DEL PAR DE UNION ESPECIFICO EN LA MUESTRA A DETERMINAR (ANALIZANDO) Y LA PROTEINA VEHICULAR SE MINIMIZA COMBINANDO PROTEINA VEHICULAR DESNATURALIZADA CON EL ANALIZANDO. SE MUESTRAN VARIOS METODOS DE ENSAYO QUE USAN LA INVENCION.
ES92908459T 1991-03-06 1992-03-05 Proteinas vehiculares desnaturalizadas para mejorar los ensayos inmunosorbentes ligados por enzimas. Expired - Lifetime ES2106179T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US66503691A 1991-03-06 1991-03-06

Publications (1)

Publication Number Publication Date
ES2106179T3 true ES2106179T3 (es) 1997-11-01

Family

ID=24668451

Family Applications (1)

Application Number Title Priority Date Filing Date
ES92908459T Expired - Lifetime ES2106179T3 (es) 1991-03-06 1992-03-05 Proteinas vehiculares desnaturalizadas para mejorar los ensayos inmunosorbentes ligados por enzimas.

Country Status (10)

Country Link
EP (1) EP0529057B1 (es)
JP (1) JP3307637B2 (es)
AT (1) ATE155583T1 (es)
AU (1) AU646738B2 (es)
CA (1) CA2081657C (es)
DE (1) DE69220863T2 (es)
DK (1) DK0529057T3 (es)
ES (1) ES2106179T3 (es)
GR (1) GR3024988T3 (es)
WO (1) WO1992015881A1 (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0760099A4 (en) * 1994-05-09 1998-12-09 Abbott Lab METHOD AND REAGENTS FOR IMPROVING THE SPECIFICITY OF AN IMMUNOASSAY
US6511812B1 (en) * 1994-05-09 2003-01-28 Abbott Laboratories Method and test kit for use in improving immunoassay specificity
PL2389204T3 (pl) 2009-01-23 2019-12-31 Royal College Of Surgeons In Ireland Rusztowanie warstwowe odpowiednie do naprawy kostno- chrzęstnej

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4407943A (en) * 1976-12-16 1983-10-04 Millipore Corporation Immobilized antibody or antigen for immunoassay
US4256724A (en) * 1978-02-21 1981-03-17 Becton, Dickinson And Company Method for non-covalent coating of antibodies on solid substrates
US4820642A (en) * 1983-04-04 1989-04-11 The Regents Of The University Of California Amplified expression vector
DE3314812A1 (de) * 1983-04-23 1984-10-25 Battelle-Institut E.V., 6000 Frankfurt Mittel zum antigen/antikoerper-nachweis
JPS60256057A (ja) * 1984-06-01 1985-12-17 Dai Ichi Pure Chem Co Ltd 免疫学的測定法
US4745182A (en) * 1984-08-24 1988-05-17 University Patents, Inc. Herpes virus specific immunological materials and methods
US4658022A (en) * 1985-08-08 1987-04-14 Molecular Diagnostics, Inc. Binding of antibody reagents to denatured protein analytes
US4959323A (en) * 1985-11-04 1990-09-25 Mt. Sinai School Of Medicine Of The City University Of New York Production and use of pre S polypeptides of hepatitis B virus
US4904581A (en) * 1986-05-06 1990-02-27 Epitope, Inc. Method of detecting AIDS virus infection
US5106726A (en) * 1990-02-16 1992-04-21 United Biomedical, Inc. Synthetic peptides specific for the detection of antibodies to HCV

Also Published As

Publication number Publication date
AU1642792A (en) 1992-10-06
EP0529057A1 (en) 1993-03-03
AU646738B2 (en) 1994-03-03
CA2081657A1 (en) 1992-09-07
CA2081657C (en) 2003-10-14
EP0529057A4 (en) 1993-10-20
ATE155583T1 (de) 1997-08-15
DE69220863T2 (de) 1998-02-26
JPH05506722A (ja) 1993-09-30
GR3024988T3 (en) 1998-01-30
JP3307637B2 (ja) 2002-07-24
DK0529057T3 (da) 1997-08-25
DE69220863D1 (de) 1997-08-21
WO1992015881A1 (en) 1992-09-17
EP0529057B1 (en) 1997-07-16

Similar Documents

Publication Publication Date Title
DE68919395D1 (de) Bestimmungsverfahren.
EP1104887A3 (en) A method and test kit for assaying collagen fragments in body fluids
SE7900662L (sv) Forfarande och reagens for immunoanalys
ES2148144T3 (es) Procedimiento para la estabilizacion de conjugados de enzima.
DK196282A (da) Fremgangsmaade samt kit til bestemmelse af antistoffer mod oploeselige antigener
EP0882985A3 (de) Immunchemische Bestimmung von multivalenten Analyten
ES2106179T3 (es) Proteinas vehiculares desnaturalizadas para mejorar los ensayos inmunosorbentes ligados por enzimas.
KR850002385A (ko) PIVKA-Ⅱ의 측정(assay)용 방법 및 시약
ATE167301T1 (de) Gruppe von getrennten peptiden
SE7714034L (sv) Forfarande for enzymkopplad immunoanalys
FR2676123B1 (fr) Complexe agglutinant et reactif d'identification d'antigenes sur les parois cellulaires.
ES2060137T3 (es) Inmunoensayo homogeneo de enzimas.
SE9500184D0 (sv) Analysmetod som utnyttjar biospecifika affinitetsreaktioner och märkt reaktant samt reagens att användas i föredragen utförandeform
ES2054686T3 (es) Equipo de inmunoensayo.
ATE108907T1 (de) Bestimmungsverfahren, seine verwendung und komponenten.
NO884131D0 (no) Agglutineringsreagens og dets anvendelse for detektering av antigene antistoffer eller andre analyter.
ITMI930477A1 (it) Saggio per la determinazione di un antigene/anticorpo in un campione di prova e corredo per l'attuazione del saggio
BR9105983A (pt) Anticorpos monoclonais que diferenciam entre proteinas de sequencias nativa e modificada
DE3863270D1 (de) Immuntest.
ATE126600T1 (de) Standard-reagenzien zur quantifizierung von hiv p24.
KR890702040A (ko) 요중의 염기성 태아단백의 측정방법 및 그것에 사용되는 측정키트
KR950033482A (ko) 항 트레포네마 팔리둠 항체의 면역 분석법
KR880014374A (ko) 아테롬성동맥경화 플라크 면역분석법

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 529057

Country of ref document: ES