ES2089318T3 - Derivados del acido piperidincarboxilico, supresor de oncogen y reactivo para la obtencion de revertientes. - Google Patents

Derivados del acido piperidincarboxilico, supresor de oncogen y reactivo para la obtencion de revertientes.

Info

Publication number
ES2089318T3
ES2089318T3 ES92114749T ES92114749T ES2089318T3 ES 2089318 T3 ES2089318 T3 ES 2089318T3 ES 92114749 T ES92114749 T ES 92114749T ES 92114749 T ES92114749 T ES 92114749T ES 2089318 T3 ES2089318 T3 ES 2089318T3
Authority
ES
Spain
Prior art keywords
piperidincarboxilico
reverters
oncogen
suppressor
reagent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES92114749T
Other languages
English (en)
Inventor
Tsuneo Ikonogi
Osamu Makabe
Yuichi Yamamoto
Osamu Itoh
Tsutomu Tsuruoka
Takayuki Usui
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Meiji Seika Kaisha Ltd
Original Assignee
Meiji Seika Kaisha Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP22919091A external-priority patent/JPH0565225A/ja
Application filed by Meiji Seika Kaisha Ltd filed Critical Meiji Seika Kaisha Ltd
Application granted granted Critical
Publication of ES2089318T3 publication Critical patent/ES2089318T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

UN NUEVO DERIVADO DE ACIDO 2-PIPERIDINACARBOXILICO REPRESENTADO POR LA FORMULA: EN DONDE X REPRESENTA UN ATOMO DE OXIGENO, UN ATOMO DE AZUFRE O UN ATOMO DE NITROGENO AL QUE SE ENLAZA UN ATOMO DE HIDROGENO; Y * REPRESENTA QUE LA CONFIGURACION DEL ATOMO DE CARBONO QUE ENLAZA AL GRUPO CARBOXILICO ES (S), (R) O UNA MEZCLA DE (S) Y (R); Y UNA SAL FARMACEUTICAMENTE ACEPTABLE DEL MISMO QUE EJERCE UN EFECTO ANTITUMORAL SOBRE UNA GRAN VARIEDAD DE CELULAS TUMORALES.
ES92114749T 1991-08-29 1992-08-28 Derivados del acido piperidincarboxilico, supresor de oncogen y reactivo para la obtencion de revertientes. Expired - Lifetime ES2089318T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP21902291 1991-08-29
JP22919091A JPH0565225A (ja) 1991-09-09 1991-09-09 発癌遺伝子抑制剤及び復帰突然変異細胞取得剤

Publications (1)

Publication Number Publication Date
ES2089318T3 true ES2089318T3 (es) 1996-10-01

Family

ID=26522874

Family Applications (1)

Application Number Title Priority Date Filing Date
ES92114749T Expired - Lifetime ES2089318T3 (es) 1991-08-29 1992-08-28 Derivados del acido piperidincarboxilico, supresor de oncogen y reactivo para la obtencion de revertientes.

Country Status (8)

Country Link
US (1) US5334723A (es)
EP (1) EP0529655B1 (es)
KR (1) KR930004264A (es)
AT (1) ATE123021T1 (es)
CA (1) CA2077025A1 (es)
DE (1) DE69202653T2 (es)
DK (1) DK0529655T3 (es)
ES (1) ES2089318T3 (es)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2594167B2 (ja) * 1990-05-21 1997-03-26 明治製菓株式会社 新規抗生物質ｓｆ２６９８物質およびその製造法

Also Published As

Publication number Publication date
DE69202653T2 (de) 1995-12-21
KR930004264A (ko) 1993-03-22
DK0529655T3 (da) 1995-08-07
EP0529655A1 (en) 1993-03-03
EP0529655B1 (en) 1995-05-24
ATE123021T1 (de) 1995-06-15
CA2077025A1 (en) 1993-03-01
DE69202653D1 (de) 1995-06-29
US5334723A (en) 1994-08-02

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