ES2089100T3 - DERIVATIVES OF 10,11,12,13-TETRA-HYDRODESMICOSIN, PROCEDURE FOR ITS PREPARATION, AND ITS USE IN THE PRODUCTION OF PHARMACEUTICAL PRODUCTS. - Google Patents

DERIVATIVES OF 10,11,12,13-TETRA-HYDRODESMICOSIN, PROCEDURE FOR ITS PREPARATION, AND ITS USE IN THE PRODUCTION OF PHARMACEUTICAL PRODUCTS.

Info

Publication number
ES2089100T3
ES2089100T3 ES91121070T ES91121070T ES2089100T3 ES 2089100 T3 ES2089100 T3 ES 2089100T3 ES 91121070 T ES91121070 T ES 91121070T ES 91121070 T ES91121070 T ES 91121070T ES 2089100 T3 ES2089100 T3 ES 2089100T3
Authority
ES
Spain
Prior art keywords
derivatives
preparation
hydrodesmicosin
tetra
procedure
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES91121070T
Other languages
Spanish (es)
Inventor
Amalija Narandja
Slobodan Djokic
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pliva Farmaceutika dd
Original Assignee
Pliva Farmaceutska Kemijska Prehrambena I Kozmeticka Industrija dd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pliva Farmaceutska Kemijska Prehrambena I Kozmeticka Industrija dd filed Critical Pliva Farmaceutska Kemijska Prehrambena I Kozmeticka Industrija dd
Application granted granted Critical
Publication of ES2089100T3 publication Critical patent/ES2089100T3/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Abstract

The invention relates to derivatives of 10,11,12,13-tetrahydro-desmycosin, <CHEM> wherein R stands for O or (OC2H5)2, R<1> stands for Si(CH3)3 or H, R<2> stands for H, OH, I or OSO2CH3, which are novel semisynthetic antibiotics of the tylosin series, possessing antibacterial activity, to their pharmaceutically acceptable salts with inorganic or organic acids, to processes for their preparation and to their use in obtaining pharmaceutical preparations.
ES91121070T 1990-12-14 1991-12-09 DERIVATIVES OF 10,11,12,13-TETRA-HYDRODESMICOSIN, PROCEDURE FOR ITS PREPARATION, AND ITS USE IN THE PRODUCTION OF PHARMACEUTICAL PRODUCTS. Expired - Lifetime ES2089100T3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
YU236390A YU236390A (en) 1990-12-14 1990-12-14 10,11,12,13-TETRAHYDRO-DESMYCOSIN DERIVATIVES AND PROCESS FOR THEIR OBTAINING

Publications (1)

Publication Number Publication Date
ES2089100T3 true ES2089100T3 (en) 1996-10-01

Family

ID=25557732

Family Applications (1)

Application Number Title Priority Date Filing Date
ES91121070T Expired - Lifetime ES2089100T3 (en) 1990-12-14 1991-12-09 DERIVATIVES OF 10,11,12,13-TETRA-HYDRODESMICOSIN, PROCEDURE FOR ITS PREPARATION, AND ITS USE IN THE PRODUCTION OF PHARMACEUTICAL PRODUCTS.

Country Status (19)

Country Link
EP (1) EP0490311B1 (en)
JP (1) JP2843695B2 (en)
CN (1) CN1030659C (en)
AT (1) ATE135708T1 (en)
BG (1) BG60571B1 (en)
CA (1) CA2056823C (en)
CZ (1) CZ280809B6 (en)
DE (1) DE69118126T2 (en)
DK (1) DK0490311T3 (en)
ES (1) ES2089100T3 (en)
GR (1) GR3019942T3 (en)
HU (2) HU215156B (en)
PL (1) PL167042B1 (en)
RO (1) RO111684B1 (en)
RU (1) RU2053238C1 (en)
SI (1) SI9012363A (en)
SK (1) SK278717B6 (en)
UA (1) UA34418C2 (en)
YU (1) YU236390A (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993014101A1 (en) * 1992-01-14 1993-07-22 Zaidan Hojin Biseibutsu Kagaku Kenkyukai 3,4'-dideoxymycaminosyltylonolide derivative and production thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4056616A (en) * 1976-03-05 1977-11-01 Schering Corporation Rosamicin derivatives and method of using same
AU551142B2 (en) * 1981-07-09 1986-04-17 Zaidan Hojin Biseibutsu Kagaku Kenkyukai Tylosin derivatives
SI8710674B (en) * 1987-04-14 1998-06-30 Pliva Process for preparation of 10,11,12,13-tetrahydro derivatives of tylosin
US5026832A (en) * 1988-12-26 1991-06-25 Toyo Jozo Co., Ltd. 9-dihydro-9-O-alkyldesmycosin derivatives
SI8911498B (en) * 1989-07-26 1998-10-31 Pliva Process for the preparation of tylosin derivatives

Also Published As

Publication number Publication date
CN1030659C (en) 1996-01-10
HUT59936A (en) 1992-07-28
SI9012363A (en) 1998-04-30
UA34418C2 (en) 2001-03-15
PL167042B1 (en) 1995-07-31
BG60571B1 (en) 1995-09-29
CS379191A3 (en) 1992-06-17
ATE135708T1 (en) 1996-04-15
CN1062535A (en) 1992-07-08
RU2053238C1 (en) 1996-01-27
SK278717B6 (en) 1998-01-14
YU236390A (en) 1993-05-28
PL292767A1 (en) 1992-11-16
CA2056823C (en) 1999-04-27
HU913937D0 (en) 1992-02-28
HU211493A9 (en) 1995-11-28
GR3019942T3 (en) 1996-08-31
BG95629A (en) 1994-03-31
DE69118126D1 (en) 1996-04-25
RO111684B1 (en) 1996-12-30
EP0490311B1 (en) 1996-03-20
EP0490311A1 (en) 1992-06-17
DK0490311T3 (en) 1996-07-22
CA2056823A1 (en) 1992-06-15
JPH05194577A (en) 1993-08-03
CZ280809B6 (en) 1996-04-17
JP2843695B2 (en) 1999-01-06
HU215156B (en) 1998-12-28
DE69118126T2 (en) 1996-10-31

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