ES2085077T3 - Derivados de sulfoxido y sulfona de aminoacidos opticamente activos, su fabricacion, su polimerizacion y uso como adsorbentes para la separacion cromatografica de racematos. - Google Patents

Derivados de sulfoxido y sulfona de aminoacidos opticamente activos, su fabricacion, su polimerizacion y uso como adsorbentes para la separacion cromatografica de racematos.

Info

Publication number
ES2085077T3
ES2085077T3 ES93109872T ES93109872T ES2085077T3 ES 2085077 T3 ES2085077 T3 ES 2085077T3 ES 93109872 T ES93109872 T ES 93109872T ES 93109872 T ES93109872 T ES 93109872T ES 2085077 T3 ES2085077 T3 ES 2085077T3
Authority
ES
Spain
Prior art keywords
optically active
amino acids
adsorbents
derivatives
racemats
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES93109872T
Other languages
English (en)
Inventor
Michael Dr Grosse-Bley
Bruno Dr Bomer
Rolf Dr Grosser
Walter Dr Lange
Franz-Peter Dr Hoever
Dieter Prof Dr Arlt
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG filed Critical Bayer AG
Application granted granted Critical
Publication of ES2085077T3 publication Critical patent/ES2085077T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B57/00—Separation of optically-active compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C07C317/44—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton
    • C07C317/48—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton the carbon skeleton being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups
    • C07C317/50—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton the carbon skeleton being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups at least one of the nitrogen atoms being part of any of the groups, X being a hetero atom, Y being any atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/04—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D277/06—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F20/00—Homopolymers and copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride, ester, amide, imide or nitrile thereof
    • C08F20/02—Monocarboxylic acids having less than ten carbon atoms, Derivatives thereof
    • C08F20/52—Amides or imides
    • C08F20/54—Amides, e.g. N,N-dimethylacrylamide or N-isopropylacrylamide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/36—Systems containing two condensed rings the rings having more than two atoms in common
    • C07C2602/42—Systems containing two condensed rings the rings having more than two atoms in common the bicyclo ring system containing seven carbon atoms
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/17—Nitrogen containing
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/18—Sulfur containing

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Polymerisation Methods In General (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)

Abstract

LA INVENCION SE REFIERE A NUEVOS DERIVADOS AMINOACIDOS OPTICAMENTE ACTIVOS DE FORMULA (I) QUE CONTIENEN GRUPOS SULFOXIDOS Y SULFONICOS. DOS VIAS DE PROCEDIMIENTO PRINCIPAL PARA LA OBTENCION DE AMINOACIDOS CONTENIENDO AZUFRE, LA POLIMERIZACION DE ESTOS MONOMEROS Y LA APLICACION DE LOS POLIMEROS COMO ADSORBENTES OPTICAMENTE ACTIVOS PARA LA SEPARACION CROMATOGRAFICA DE RACEMATOS EN LOS ENANTIOMEROS. TENIENDO: N, R, R1, R2, R3, X UN SIGNIFICADO DESCRITO EN LA PATENTE.
ES93109872T 1992-07-02 1993-06-21 Derivados de sulfoxido y sulfona de aminoacidos opticamente activos, su fabricacion, su polimerizacion y uso como adsorbentes para la separacion cromatografica de racematos. Expired - Lifetime ES2085077T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4221711A DE4221711A1 (de) 1992-07-02 1992-07-02 Optisch aktive Aminosäuresulfoxid- und sulfon-Derivate, ihre Herstellung, ihre Polymerisation und Verwendung als Adsorbentien für die chromatographische Racematspaltung

Publications (1)

Publication Number Publication Date
ES2085077T3 true ES2085077T3 (es) 1996-05-16

Family

ID=6462316

Family Applications (1)

Application Number Title Priority Date Filing Date
ES93109872T Expired - Lifetime ES2085077T3 (es) 1992-07-02 1993-06-21 Derivados de sulfoxido y sulfona de aminoacidos opticamente activos, su fabricacion, su polimerizacion y uso como adsorbentes para la separacion cromatografica de racematos.

Country Status (8)

Country Link
US (2) US5357001A (es)
EP (1) EP0576949B1 (es)
JP (1) JP3334263B2 (es)
AT (1) ATE133660T1 (es)
DE (2) DE4221711A1 (es)
DK (1) DK0576949T3 (es)
ES (1) ES2085077T3 (es)
GR (1) GR3019209T3 (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5616775A (en) * 1994-05-05 1997-04-01 Bristol-Myers Squibb Co. Process for preparing homocystein analogs useful as intermediates for compounds containing a fused bicyclic ring
DE19546136A1 (de) 1995-12-11 1997-06-12 Bayer Ag Chirale stationäre Phasen für die chromatographische Trennung von optischen Isomeren
WO2002070123A1 (fr) * 2001-03-07 2002-09-12 Daicel Chemical Industries, Ltd. Agent de séparation pour isomère optique
JP4677623B2 (ja) * 2005-05-16 2011-04-27 独立行政法人産業技術総合研究所 液体クロマトグラフィー用担体、該担体を充填したクロマトグラフィー用カラム、及び該カラムを用いた有機物の分離方法
JP5190640B2 (ja) * 2007-06-18 2013-04-24 独立行政法人産業技術総合研究所 アルキルスルフィニル基またはアルキルスルホニル基を有するクロマトグラフィー担体及びその製造方法
WO2013103598A2 (en) 2012-01-06 2013-07-11 Novus International Inc. Sulfoxide-based surfactants
WO2013119959A1 (en) 2012-02-09 2013-08-15 Novus International Inc. Heteroatom containing cyclic dimers
CA2878617A1 (en) 2012-07-12 2014-01-16 Houston Stephen Smith Matrix and layer compositions for protection of bioactives
SG11201803979PA (en) 2015-11-12 2018-06-28 Novus Int Inc Sulfur-containing compounds as solvents
US10584306B2 (en) 2017-08-11 2020-03-10 Board Of Regents Of The University Of Oklahoma Surfactant microemulsions
WO2022024997A1 (ja) * 2020-07-27 2022-02-03 株式会社カネカ 有機重合体、硬化性組成物、及び硬化物

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3615624A (en) * 1968-01-29 1971-10-26 Eastman Kodak Co Peptizers for silver halide emulsions useful in photography
GB1380898A (en) * 1970-12-11 1975-01-15 Koch Light Lab Ltd Bonding of enzymes enzyme derivatives and other biologically active compounds to polymeric materials and polymeric materials to which such biologically active compounds can be bound
JPS4867382A (es) * 1971-12-06 1973-09-14
SE470099B (sv) * 1984-05-17 1993-11-08 Jerker Porath Sulfonaktiverade tioeteradsorbenter för separation av t ex protein
DE3706890A1 (de) * 1987-03-04 1988-09-15 Bayer Ag Optisch aktive (meth)acrylamide, verfahren zu ihrer herstellung und ihre verwendung zur racematspaltung
US5274167A (en) * 1989-01-26 1993-12-28 Bayer Aktiengesellschaft Polymeriable optically active (meth) acrylic acid derivatives
EP0379917B1 (de) * 1989-01-26 1995-08-09 Bayer Ag Optisch aktive (Meth)Acrylsäure-Derivate, ihre Herstellung, ihre Polymerisation zu optisch aktiven Polymeren und deren Verwendung
DE4021108A1 (de) * 1990-07-03 1992-01-09 Bayer Ag Optisch aktive n-(alpha)-fluoracryloyl-aminosaeure-derivate, ihre herstellung, die daraus hergestellten optisch aktiven polymeren und deren verwendung zur spaltung von racematen
US5202456A (en) * 1991-04-15 1993-04-13 The President And Fellows Of Harvard College Compounds for inhibition of protein methylation
DE4120695A1 (de) * 1991-06-22 1992-12-24 Bayer Ag Optisch aktive schwefelhaltige aminosaeure-derivate, ihre herstellung, ihre polymerisation zu optisch aktiven polymeren und deren verwendung

Also Published As

Publication number Publication date
GR3019209T3 (en) 1996-06-30
DE59301531D1 (de) 1996-03-14
JPH07291922A (ja) 1995-11-07
EP0576949B1 (de) 1996-01-31
DK0576949T3 (da) 1996-06-03
US5481026A (en) 1996-01-02
JP3334263B2 (ja) 2002-10-15
EP0576949A1 (de) 1994-01-05
DE4221711A1 (de) 1994-01-05
US5357001A (en) 1994-10-18
ATE133660T1 (de) 1996-02-15

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