ES2083343T3 - Vacunas recombinantes vivas contra patogenos entericos gram negativos. - Google Patents

Vacunas recombinantes vivas contra patogenos entericos gram negativos.

Info

Publication number
ES2083343T3
ES2083343T3 ES92106281T ES92106281T ES2083343T3 ES 2083343 T3 ES2083343 T3 ES 2083343T3 ES 92106281 T ES92106281 T ES 92106281T ES 92106281 T ES92106281 T ES 92106281T ES 2083343 T3 ES2083343 T3 ES 2083343T3
Authority
ES
Spain
Prior art keywords
strains
enteric pathogens
vaccines against
live recombinant
recombinant vaccines
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES92106281T
Other languages
English (en)
Other versions
ES2083343T1 (es
Inventor
Jean-Francois Viret
Stanly J Cryz Jr
Didier Favre
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cilag GmbH International
Original Assignee
Schweiz Serum und Impfinstitut Bern
Schweiz Serum und Impfinstitut und Institut zur Erforschung der Infektionskrankheiten
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schweiz Serum und Impfinstitut Bern, Schweiz Serum und Impfinstitut und Institut zur Erforschung der Infektionskrankheiten filed Critical Schweiz Serum und Impfinstitut Bern
Publication of ES2083343T1 publication Critical patent/ES2083343T1/es
Application granted granted Critical
Publication of ES2083343T3 publication Critical patent/ES2083343T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/107—Vibrio
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/025—Enterobacteriales, e.g. Enterobacter
    • A61K39/0283—Shigella
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/24—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
    • C07K14/245—Escherichia (G)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/24—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
    • C07K14/25—Shigella (G)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/28—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Vibrionaceae (F)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
    • A61K2039/522—Bacterial cells; Fungal cells; Protozoal cells avirulent or attenuated
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Public Health (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Immunology (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biotechnology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • General Engineering & Computer Science (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biomedical Technology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

LA PRESENTE INVENCION SE REFIERE A CEPAS BACTERIANAS ATENUADAS VIVAS RECOMBINANTES QUE EXPRESAN DETERMINANTES DE O-SEROTIPO DE PATOGENOS ENTERICOS GRAM NEGATIVO DE UNA FORMA COVALENTEMENTE ENLAZADA A UN NUCLEO, PORTADORAS DE RECOMBINANTE PUEDEN SER USADAS COMO VACUNAS VIVAS PARA LA INMUNIZACION ORAL CONTRA POR EJEMPLO LA DISENTERIA BACILAR CAUSADA POR CEPAS VIRULENTAS DE SHIGELLA SPP.
ES92106281T 1992-04-10 1992-04-10 Vacunas recombinantes vivas contra patogenos entericos gram negativos. Expired - Lifetime ES2083343T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP92106281A EP0564689B1 (en) 1992-04-10 1992-04-10 Recombinant live vaccines against Gram-negative enteric pathogens
SG1996001047A SG46987A1 (en) 1992-04-10 1992-04-10 Recombinant live vaccines

Publications (2)

Publication Number Publication Date
ES2083343T1 ES2083343T1 (es) 1996-04-16
ES2083343T3 true ES2083343T3 (es) 1997-12-01

Family

ID=26130874

Family Applications (1)

Application Number Title Priority Date Filing Date
ES92106281T Expired - Lifetime ES2083343T3 (es) 1992-04-10 1992-04-10 Vacunas recombinantes vivas contra patogenos entericos gram negativos.

Country Status (7)

Country Link
EP (1) EP0564689B1 (es)
AT (1) ATE155690T1 (es)
DE (2) DE69221120T2 (es)
DK (1) DK0564689T3 (es)
ES (1) ES2083343T3 (es)
GR (1) GR3024848T3 (es)
SG (1) SG46987A1 (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0692031B1 (en) * 1993-02-22 2007-04-11 The General Hospital Corporation Heterologous antigens in live cell vaccine strains
US20020028215A1 (en) 1999-08-09 2002-03-07 Jagath L. Kadurugamuwa Novel vaccines and pharmaceutical compositions using membrane vesicles of microorganisms, and methods for preparing same
AU707131B2 (en) * 1995-08-04 1999-07-01 University Of Guelph Novel vaccines and pharmaceutical compositions using membrane vesicles of microorganisms, and methods for preparing same
GR950300072T1 (en) * 1995-10-13 1996-01-31 Schweiz Serum & Impfinst Recombinant live vaccines against Gram-negative enteric pathogens
US6036953A (en) * 1996-11-29 2000-03-14 The General Hospital Corporation Heterologous antigens in live cell V. cholerae strains
US6399074B1 (en) 1998-07-24 2002-06-04 Megan Health, Inc. Live attenuated salmonella vaccines to control avian pathogens
CA2390304A1 (en) * 1999-11-10 2001-05-17 Malcolm B. Perry Live bacterial vaccines against escherichia coli o157:h7
EP1543836A1 (en) * 2003-12-17 2005-06-22 Berna Biotech AG Recombinant Vibrio cholerae strain and vaccine comprising said strain

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3856935A (en) * 1971-04-29 1974-12-24 Schweiz Serum & Impfinst Oral typhoid vaccine and method of preparing the same
US4632830A (en) * 1981-07-31 1986-12-30 The United States Of America As Represented By The Secretary Of The Army Oral vaccine for immunization against enteric disease
GB8314645D0 (en) * 1983-05-26 1983-06-29 Wellcome Found Bivalent vaccines
EP0250614A1 (en) * 1986-06-23 1988-01-07 Serum Und Impfinstitut Und Institut Zur Erforschung Der Infektionskrankheiten Schweiz. DNA fragments encoding the chromosomal nucleotide sugar synthetases and glycosyl transferases
JPH03501326A (ja) * 1988-06-20 1991-03-28 ルミニス・プロプライアタリー・リミテッド 血清型分類用ｄｎａプローブ
AR242989A1 (es) * 1988-07-15 1993-06-30 Inst Pasteur I Nat De La Sante Metodo para modificar una cepa salvaje de una shigella entero-invasora para producir una cepa modificada apta para preparar una vacuna contra la cepa salvaje y cepa de shigella asi modificada.
WO1991018092A1 (en) * 1990-05-23 1991-11-28 University Of Maryland At Baltimore Acid-tolerant salmonella typhi, double aro mutants thereof and use as an oral vaccine for typhoid fever

Also Published As

Publication number Publication date
EP0564689B1 (en) 1997-07-23
DK0564689T3 (da) 1998-02-16
DE564689T1 (de) 1996-06-27
ES2083343T1 (es) 1996-04-16
ATE155690T1 (de) 1997-08-15
EP0564689A1 (en) 1993-10-13
DE69221120D1 (de) 1997-08-28
SG46987A1 (en) 1998-03-20
DE69221120T2 (de) 1998-02-26
GR3024848T3 (en) 1998-01-30

Similar Documents

Publication Publication Date Title
Choi-Kim et al. Relationship between the iron regulated outer membrane proteins and the outer membrane proteins of in vivo grown Pasteurella multocida
EP0692031A4 (en) HETEROLOGOUS ANTIGENS PRESENT IN VACCINE STRAINS WITH LIVING CELLS
DE69713408T2 (de) Streptococcus equi Impstoff
ES2083343T3 (es) Vacunas recombinantes vivas contra patogenos entericos gram negativos.
EP0500699A4 (en) Cross-protective salmonella vaccines
GR3035135T3 (en) Poultry vaccine containing infections bronchitis virus serotype 4/91.
PT650733E (pt) Vacina in ovo viva atenuada
PL303482A1 (en) Vaccine against infection with streptococcus suis, streptococcus suis polypeptide and method of preparing such vaccine
FI955150A0 (fi) OspC-antigeenirokotteiden immunogeenisia formulaatioita lyymisairauden ehkäisyyn ja hoitoon ja rekombinanttimenetelmiä antigeenien valmistamiseksi
NZ335050A (en) Helicobacter pylori live vaccine
ES8302086A1 (es) Un procedimiento para preparar vacunas de pasteurella multocida y pasteunella haemolytica vivas modificadas con efectos veterinarios, particularmente para especies de animales bovinos, porcinos y ovinos.
Davies et al. Comparison of outer-membrane proteins of Pasteurella haemolytica expressed in vitro and in vivo in cattle
Sippel et al. Homogeneity of protein serotype antigens in Neisseria meningitidis group A
NZ295877A (en) A vaccine comprising the helicobacter bacterium and its use
JPS5781415A (en) Single strain vaccine for infectious disease by some strains of cilia bacteria
GB2248241B (en) Cultivation method for preparing an oral live typhoid vaccine
Sibalin Cross-neutralization tests with swine enterovirus strain S 180/4, and Teschen, Talfan, and swine polio-encephalomyelitis viruses
DE69208854T2 (de) Impfstoff-Zubereitung zur Vorbeugung gegen bei Tieren durch Chlamydia psitacci verursachte Fehlgeburt
DE3750549T2 (de) Impfstoff gegen schweinedysenterie.
Lindberg Shigella vaccines: current status and prospects for the future
WO2024025936A3 (en) Development of carbohydrate-based anti-salmonella vaccines
Newland et al. Evaluation of a bivalent Escherichia coli-Shigella hybrid vaccine expressing S. Sonnei and S. Flexneri 2A somatic antigens
Chart et al. Intra‐strain heterogeneity in expression of lipopolysaccharide by strains of Salmonella virchow
Pennington Pseudomonas aeruginosa immunization
Knittel et al. Diagnosis of porcine proliferative enteritis.

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 564689

Country of ref document: ES