ES2080452T3 - Uso de bifosfonatos para la fabricacion de un medicamento para el bloqueo de la transformacion neoplasica de celulas inducida por oncogenes ras. - Google Patents
Uso de bifosfonatos para la fabricacion de un medicamento para el bloqueo de la transformacion neoplasica de celulas inducida por oncogenes ras.Info
- Publication number
- ES2080452T3 ES2080452T3 ES92309185T ES92309185T ES2080452T3 ES 2080452 T3 ES2080452 T3 ES 2080452T3 ES 92309185 T ES92309185 T ES 92309185T ES 92309185 T ES92309185 T ES 92309185T ES 2080452 T3 ES2080452 T3 ES 2080452T3
- Authority
- ES
- Spain
- Prior art keywords
- biphosphonates
- manufacture
- block
- medicinal product
- cells induced
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/665—Phosphorus compounds having oxygen as a ring hetero atom, e.g. fosfomycin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/67—Phosphorus compounds having sulfur as a ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
SE PRESENTA UN METODO PARA BLOQUEAR O EVITAR LA PRENILACION DE LA CUBIERTA CAAX QUE CONTIENE PROTEINAS QUE INCLUYEN PRODUCTOS DEL ONCOGENE RAS EVITANDO Y/O TRATANDO TUMORES RELACIONADOS CON EL RAS, EL METODO INCLUYE EL PASO DE LA ADMINISTRACION DE UNA CANTIDAD TERAPEUTICAMENTE EFECTIVA DE UN INHIBIDOR DE LA TRANSFERASA PRENIL DE LA PROTEINA QUE ES UN BISFOSFONATO O UN ANALOGO DEL MISMO.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US77491191A | 1991-10-11 | 1991-10-11 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2080452T3 true ES2080452T3 (es) | 1996-02-01 |
Family
ID=25102663
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES92309185T Expired - Lifetime ES2080452T3 (es) | 1991-10-11 | 1992-10-08 | Uso de bifosfonatos para la fabricacion de un medicamento para el bloqueo de la transformacion neoplasica de celulas inducida por oncogenes ras. |
Country Status (8)
Country | Link |
---|---|
EP (1) | EP0537008B1 (es) |
JP (1) | JPH05201869A (es) |
AT (1) | ATE129407T1 (es) |
CA (1) | CA2080158A1 (es) |
DE (1) | DE69205657T2 (es) |
DK (1) | DK0537008T3 (es) |
ES (1) | ES2080452T3 (es) |
GR (1) | GR3018754T3 (es) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5451401A (en) * | 1993-09-29 | 1995-09-19 | The Procter & Gamble Company | Diphosphonic acid esters as tartar control agents |
US5574025A (en) * | 1994-10-26 | 1996-11-12 | Merck & Co., Inc. | Inhibitors of prenyl-protein transferases |
GB9422814D0 (en) * | 1994-11-11 | 1995-01-04 | Medinnova Sf | Chemical method |
EP0856315B1 (en) * | 1995-08-09 | 2005-08-24 | Banyu Pharmaceutical Co., Ltd. | Protein-farnesyltransferase inhibitors in combination with hmgcoa-reductase-inhibitors for the treatment of aids |
US6117641A (en) | 1996-04-11 | 2000-09-12 | Mitotix, Inc. | Assays and reagents for identifying anti-fungal agents and uses related thereto |
AU717165B2 (en) | 1996-04-11 | 2000-03-16 | Gpc Biotech Inc. | Assays and reagents for identifying anti-fungal agents, and uses related thereto |
US6727082B1 (en) | 1996-04-11 | 2004-04-27 | Gpc Biotech Inc. | Assays and reagents for identifying anti-fungal agents, and uses related thereto |
CA2334645A1 (en) * | 1998-06-24 | 1999-12-29 | Hassan Jomaa | Combined preparation of anti-infectiously active compounds which inhibit the 2-c-methylerythrose-4 metabolic pathway, and inhibitors of lipid metabolism |
CA2352486A1 (en) * | 1998-11-25 | 2000-06-02 | Genetica, Inc. | Methods and reagents for increasing proliferative capacity and preventing replicative senescence |
CA2451881A1 (fr) | 2001-07-16 | 2003-01-30 | Universite Paris 13 | Nouveaux derives de bisphosphonates, leurs preparations et utilisations |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2018470A1 (en) * | 1989-07-17 | 1991-01-17 | Scott Adams Biller | Phosphorus-containing squalene synthetase inhibitors and method |
JPH05163150A (ja) * | 1991-05-13 | 1993-06-29 | E R Squibb & Sons Inc | アテローム性動脈硬化症の抑制・治療剤 |
-
1992
- 1992-10-08 DE DE69205657T patent/DE69205657T2/de not_active Expired - Fee Related
- 1992-10-08 AT AT92309185T patent/ATE129407T1/de not_active IP Right Cessation
- 1992-10-08 CA CA002080158A patent/CA2080158A1/en not_active Abandoned
- 1992-10-08 ES ES92309185T patent/ES2080452T3/es not_active Expired - Lifetime
- 1992-10-08 EP EP92309185A patent/EP0537008B1/en not_active Expired - Lifetime
- 1992-10-08 DK DK92309185.4T patent/DK0537008T3/da active
- 1992-10-12 JP JP4272809A patent/JPH05201869A/ja not_active Withdrawn
-
1996
- 1996-01-23 GR GR960400153T patent/GR3018754T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
GR3018754T3 (en) | 1996-04-30 |
CA2080158A1 (en) | 1993-04-12 |
JPH05201869A (ja) | 1993-08-10 |
DE69205657D1 (de) | 1995-11-30 |
ATE129407T1 (de) | 1995-11-15 |
DK0537008T3 (da) | 1995-12-04 |
EP0537008A1 (en) | 1993-04-14 |
DE69205657T2 (de) | 1996-06-13 |
EP0537008B1 (en) | 1995-10-25 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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