ES2075836T3 - Lentes multifocales que utilizan escalones de desplazamiento. - Google Patents
Lentes multifocales que utilizan escalones de desplazamiento.Info
- Publication number
- ES2075836T3 ES2075836T3 ES88310561T ES88310561T ES2075836T3 ES 2075836 T3 ES2075836 T3 ES 2075836T3 ES 88310561 T ES88310561 T ES 88310561T ES 88310561 T ES88310561 T ES 88310561T ES 2075836 T3 ES2075836 T3 ES 2075836T3
- Authority
- ES
- Spain
- Prior art keywords
- lenses
- multifocal lenses
- displacement steps
- images
- phase
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 238000006073 displacement reaction Methods 0.000 title 1
- QURLONWWPWCPIC-UHFFFAOYSA-N 2-(2-aminoethoxy)ethanol;3,6-dichloro-2-methoxybenzoic acid Chemical compound NCCOCCO.COC1=C(Cl)C=CC(Cl)=C1C(O)=O QURLONWWPWCPIC-UHFFFAOYSA-N 0.000 abstract 1
- 230000003287 optical effect Effects 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B5/00—Optical elements other than lenses
- G02B5/18—Diffraction gratings
- G02B5/1876—Diffractive Fresnel lenses; Zone plates; Kinoforms
- G02B5/189—Structurally combined with optical elements not having diffractive power
- G02B5/1895—Structurally combined with optical elements not having diffractive power such optical elements having dioptric power
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/14—Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
- A61F2/16—Intraocular lenses
- A61F2/1613—Intraocular lenses having special lens configurations, e.g. multipart lenses; having particular optical properties, e.g. pseudo-accommodative lenses, lenses having aberration corrections, diffractive lenses, lenses for variably absorbing electromagnetic radiation, lenses having variable focus
- A61F2/1616—Pseudo-accommodative, e.g. multifocal or enabling monovision
- A61F2/1618—Multifocal lenses
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B3/00—Simple or compound lenses
- G02B3/10—Bifocal lenses; Multifocal lenses
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B5/00—Optical elements other than lenses
- G02B5/18—Diffraction gratings
- G02B5/1876—Diffractive Fresnel lenses; Zone plates; Kinoforms
-
- G—PHYSICS
- G02—OPTICS
- G02C—SPECTACLES; SUNGLASSES OR GOGGLES INSOFAR AS THEY HAVE THE SAME FEATURES AS SPECTACLES; CONTACT LENSES
- G02C7/00—Optical parts
- G02C7/02—Lenses; Lens systems ; Methods of designing lenses
- G02C7/04—Contact lenses for the eyes
- G02C7/041—Contact lenses for the eyes bifocal; multifocal
- G02C7/042—Simultaneous type
-
- G—PHYSICS
- G02—OPTICS
- G02C—SPECTACLES; SUNGLASSES OR GOGGLES INSOFAR AS THEY HAVE THE SAME FEATURES AS SPECTACLES; CONTACT LENSES
- G02C7/00—Optical parts
- G02C7/02—Lenses; Lens systems ; Methods of designing lenses
- G02C7/04—Contact lenses for the eyes
- G02C7/041—Contact lenses for the eyes bifocal; multifocal
- G02C7/044—Annular configuration, e.g. pupil tuned
-
- G—PHYSICS
- G02—OPTICS
- G02C—SPECTACLES; SUNGLASSES OR GOGGLES INSOFAR AS THEY HAVE THE SAME FEATURES AS SPECTACLES; CONTACT LENSES
- G02C7/00—Optical parts
- G02C7/02—Lenses; Lens systems ; Methods of designing lenses
- G02C7/06—Lenses; Lens systems ; Methods of designing lenses bifocal; multifocal ; progressive
-
- G—PHYSICS
- G02—OPTICS
- G02C—SPECTACLES; SUNGLASSES OR GOGGLES INSOFAR AS THEY HAVE THE SAME FEATURES AS SPECTACLES; CONTACT LENSES
- G02C2202/00—Generic optical aspects applicable to one or more of the subgroups of G02C7/00
- G02C2202/20—Diffractive and Fresnel lenses or lens portions
Landscapes
- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Ophthalmology & Optometry (AREA)
- General Physics & Mathematics (AREA)
- Optics & Photonics (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Transplantation (AREA)
- Engineering & Computer Science (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Eyeglasses (AREA)
- Materials For Medical Uses (AREA)
- Superconductors And Manufacturing Methods Therefor (AREA)
- Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
- Absorbent Articles And Supports Therefor (AREA)
Abstract
ESTA INVENCION ES RELATIVA A UNA CONFIGURACION DE LENTES OPTICAS MULTIFOCALES QUE SE BASA SOBRE EL FENOMENO DE VISION SIMULTANEA POR LO QUE AL OJO SE LE PRESENTAS DOS IMAGENES EN UNA. EN PARTICULAR ESTA INVENCION PERMITE HACER UNAS LENTES CON RELATIVAMENTE ABSOLUTA CLARIDAD ENTRE IMAGENES MULTIPLES. DE ESTE MODO, POR EJEMPLO, LAS LENTES PUEDEN COMPRENDER UNA LENTE PORTADORA CL, LA SUPERFICIE DELANTERA I DE LA CUAL ESTA DIVIDIDA EN SEIS ZONAS ANULARES CONCENTRICAS, LIMITADAS POR RADIOS R1-R6 DE TAL MODO QUE FORMAN UNA LAMINA DE FASE TRIFOCAL.FIG 15.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/863,069 US5017000A (en) | 1986-05-14 | 1986-05-14 | Multifocals using phase shifting |
EP88310561A EP0367878B1 (en) | 1986-05-14 | 1988-11-10 | Multifocals using phase shifting steps |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2075836T3 true ES2075836T3 (es) | 1995-10-16 |
Family
ID=26117093
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES88310561T Expired - Lifetime ES2075836T3 (es) | 1986-05-14 | 1988-11-10 | Lentes multifocales que utilizan escalones de desplazamiento. |
Country Status (7)
Country | Link |
---|---|
US (1) | US5017000A (es) |
EP (1) | EP0367878B1 (es) |
AT (1) | ATE126900T1 (es) |
AU (1) | AU623343B2 (es) |
CA (1) | CA1318799C (es) |
DE (1) | DE3854350T2 (es) |
ES (1) | ES2075836T3 (es) |
Families Citing this family (90)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5201762A (en) * | 1987-05-20 | 1993-04-13 | Hauber Frederick A | Intraocular archromatic lens |
IE73484B1 (en) * | 1988-07-20 | 1997-06-04 | Allen L Cohen | Multifocal diffractive optical device |
US5044706A (en) * | 1990-02-06 | 1991-09-03 | Hughes Aircraft Company | Optical element employing aspherical and binary grating optical surfaces |
US5117306A (en) * | 1990-07-17 | 1992-05-26 | Cohen Allen L | Diffraction bifocal with adjusted chromaticity |
US5229797A (en) * | 1990-08-08 | 1993-07-20 | Minnesota Mining And Manufacturing Company | Multifocal diffractive ophthalmic lenses |
GB2256500A (en) * | 1991-05-03 | 1992-12-09 | Minnesota Mining & Mfg | Diffractive mirror having diffractive zones seperated by optical steps |
DE4134518A1 (de) * | 1991-10-18 | 1993-04-22 | Adatomed Pharma & Med | Ophthalmische linse |
US5245366A (en) * | 1991-10-31 | 1993-09-14 | Svochak Jan B | Bifocal contact lens and method of making same |
US5260828A (en) * | 1992-03-27 | 1993-11-09 | Polaroid Corporation | Methods and means for reducing temperature-induced variations in lenses and lens devices |
US5344447A (en) * | 1992-11-12 | 1994-09-06 | Massachusetts Institute Of Technology | Diffractive trifocal intra-ocular lens design |
US5760871A (en) * | 1993-01-06 | 1998-06-02 | Holo-Or Ltd. | Diffractive multi-focal lens |
US5815293A (en) * | 1993-02-01 | 1998-09-29 | Matsushita Electric Industrial Co., Ltd. | Compound objective lens having two focal points |
JP2532818B2 (ja) * | 1993-02-01 | 1996-09-11 | 松下電器産業株式会社 | 対物レンズおよび光ヘッド装置 |
US5631762A (en) * | 1993-06-04 | 1997-05-20 | Hitachi Koki Co., Ltd. | Multi-beam generating element and optical printing apparatus therewith |
US5895422A (en) * | 1993-06-17 | 1999-04-20 | Hauber; Frederick A. | Mixed optics intraocular achromatic lens |
US5543966A (en) * | 1993-12-29 | 1996-08-06 | Eastman Kodak Company | Hybrid refractive/diffractive achromatic camera lens |
US5581405A (en) * | 1993-12-29 | 1996-12-03 | Eastman Kodak Company | Hybrid refractive/diffractive achromatic camera lens and camera using such |
DE59509367D1 (de) * | 1994-03-17 | 2001-08-02 | Bifocon Optics Forsch & Entw | Zonenlinse |
US5699142A (en) * | 1994-09-01 | 1997-12-16 | Alcon Laboratories, Inc. | Diffractive multifocal ophthalmic lens |
US5715031A (en) * | 1995-05-04 | 1998-02-03 | Johnson & Johnson Vision Products, Inc. | Concentric aspheric multifocal lens designs |
DE19619478A1 (de) * | 1996-05-14 | 1997-11-20 | Sick Ag | Optische Anordnung mit diffraktivem optischem Element |
US6061324A (en) * | 1996-10-23 | 2000-05-09 | Konica Corporation | Method for recording/reproducing optical information recording medium, optical pickup apparatus, objective lens and design method of objective lens |
EP1884944B1 (en) | 1997-03-13 | 2014-08-27 | Hitachi Maxell, Ltd. | Compatible objective lens |
JP3472097B2 (ja) | 1997-08-20 | 2003-12-02 | キヤノン株式会社 | 回折光学素子及びそれを用いた光学系 |
US6158862A (en) * | 1997-12-04 | 2000-12-12 | Alcon Laboratories, Inc. | Method of reducing glare associated with multifocal ophthalmic lenses |
US6392805B1 (en) * | 1998-03-23 | 2002-05-21 | Minolta Co., Ltd. | Diffractive optical element and an optical system having a diffractive optical element |
JP3827860B2 (ja) * | 1998-03-31 | 2006-09-27 | パイオニア株式会社 | 対物レンズ及び光ピックアップ装置 |
US6120148A (en) * | 1998-10-05 | 2000-09-19 | Bifocon Optics Gmbh | Diffractive lens |
DE29902409U1 (de) * | 1999-02-11 | 1999-05-20 | Werkhaus Design & Produktion G | Fliegenaugenbrille |
DE19926512A1 (de) * | 1999-06-10 | 2000-12-14 | Acritec Gmbh | Intraokularlinse |
JP3486606B2 (ja) | 2000-09-08 | 2004-01-13 | キヤノン株式会社 | 回折光学素子およびそれを用いた光学系 |
US7245407B2 (en) | 2002-06-10 | 2007-07-17 | Matsushita Electric Industrial Co., Ltd. | Complex objective lens compatible with information media of different thicknesses |
US7896916B2 (en) | 2002-11-29 | 2011-03-01 | Amo Groningen B.V. | Multifocal ophthalmic lens |
SE0203564D0 (sv) | 2002-11-29 | 2002-11-29 | Pharmacia Groningen Bv | Multifocal opthalmic lens |
US6951391B2 (en) * | 2003-06-16 | 2005-10-04 | Apollo Optical Systems Llc | Bifocal multiorder diffractive lenses for vision correction |
US7287852B2 (en) | 2003-06-30 | 2007-10-30 | Fiala Werner J | Intra-ocular lens or contact lens exhibiting large depth of focus |
US20050027354A1 (en) * | 2003-07-28 | 2005-02-03 | Advanced Medical Optics, Inc. | Primary and supplemental intraocular lens |
FR2872590B1 (fr) * | 2004-07-02 | 2006-10-27 | Essilor Int | Procede de realisation d'un verre ophtalmique et composant optique adapte pour la mise en oeuvre de ce procede |
US7156516B2 (en) * | 2004-08-20 | 2007-01-02 | Apollo Optical Systems Llc | Diffractive lenses for vision correction |
US7025456B2 (en) * | 2004-08-20 | 2006-04-11 | Apollo Optical Systems, Llc | Diffractive lenses for vision correction |
US7506983B2 (en) | 2004-09-30 | 2009-03-24 | The Hong Kong Polytechnic University | Method of optical treatment |
EP2527908B1 (en) | 2004-10-25 | 2019-03-20 | Johnson & Johnson Surgical Vision, Inc. | Ophthalmic lens with multiple phase plates |
US7922326B2 (en) | 2005-10-25 | 2011-04-12 | Abbott Medical Optics Inc. | Ophthalmic lens with multiple phase plates |
FR2879757B1 (fr) * | 2004-12-17 | 2007-07-13 | Essilor Int | Procede de realisation d'un element optique transparent, composant optique intervenant dans ce procede et element optique ainsi obtenu |
FR2888948B1 (fr) * | 2005-07-20 | 2007-10-12 | Essilor Int | Composant optique transparent pixellise comprenant un revetement absorbant, son procede de realisation et son utilisation dans un element optique |
FR2888947B1 (fr) * | 2005-07-20 | 2007-10-12 | Essilor Int | Composant optique a cellules |
FR2888951B1 (fr) * | 2005-07-20 | 2008-02-08 | Essilor Int | Composant optique pixellise aleatoirement, son procede de fabrication, et son utilisation dans la fabrication d'un element optique transparent |
US7441894B2 (en) | 2006-02-09 | 2008-10-28 | Alcon Manufacturing, Ltd. | Pseudo-accommodative IOL having diffractive zones with varying areas |
US7481532B2 (en) | 2006-02-09 | 2009-01-27 | Alcon, Inc. | Pseudo-accommodative IOL having multiple diffractive patterns |
FR2907559B1 (fr) * | 2006-10-19 | 2009-02-13 | Essilor Int | Composant optique elecro-commandable comprenant un ensemble de cellules |
US20080137030A1 (en) * | 2006-11-03 | 2008-06-12 | Hoffman William C | Optical devices with reduced chromatic aberration |
FR2910642B1 (fr) * | 2006-12-26 | 2009-03-06 | Essilor Int | Composant optique transparent a deux ensembles de cellules |
FR2911404B1 (fr) * | 2007-01-17 | 2009-04-10 | Essilor Int | Composant optique transparent a cellules remplies de materiau optique |
EP2171517A4 (en) * | 2007-07-31 | 2012-02-29 | Battelle Energy Alliance Llc | VISUAL OPTICS AND METHOD OF VISIBILITY |
CA2729175C (en) | 2008-07-15 | 2016-11-01 | Alcon, Inc. | An extended depth of focus (edof) lens to increase pseudo-accommodation by utilizing pupil dynamics |
FR2936880B1 (fr) | 2008-10-07 | 2011-03-11 | Essilor Int | Verre ophtalmique multifocal. |
FR2936879B1 (fr) | 2008-10-07 | 2011-03-11 | Essilor Int | Verre ophtalmique corrigeant la vision foveale et la vision peripherique. |
JP5203160B2 (ja) | 2008-12-05 | 2013-06-05 | Hoya株式会社 | 回折型多焦点レンズ |
US8216307B2 (en) * | 2008-12-19 | 2012-07-10 | Novartis Ag | Radially segmented apodized diffractive multifocal design for ocular implant |
WO2010079528A1 (ja) * | 2009-01-06 | 2010-07-15 | 株式会社メニコン | 回折レンズの製造方法 |
JP5797563B2 (ja) * | 2009-03-04 | 2015-10-21 | パーフェクト アイピー エルエルシーPerfect Ip,Llc | 角膜の特性を測定して眼用レンズを得るためのシステムおよび方法 |
US9370416B2 (en) | 2009-08-27 | 2016-06-21 | Jagrat Natavar DAVE | Refractive-diffractive lens |
ATE557307T1 (de) | 2009-08-27 | 2012-05-15 | Polymer Technologies Internat Eou | Refraktiv-diffraktive linse |
KR101798031B1 (ko) * | 2009-10-26 | 2017-11-15 | 노바르티스 아게 | 안구 임플란트를 위한 위상-시프트된 중심-거리 회절 설계 |
EP2591025B1 (en) | 2010-07-05 | 2016-10-05 | Dave, Jagrat Natavar | Polymeric composition for ocular devices |
US8992611B2 (en) | 2010-09-03 | 2015-03-31 | Abbott Medical Optics Inc. | Microincision lens |
US20120140166A1 (en) | 2010-12-07 | 2012-06-07 | Abbott Medical Optics Inc. | Pupil dependent diffractive lens for near, intermediate, and far vision |
US8678583B2 (en) * | 2012-05-09 | 2014-03-25 | Allen Louis Cohen | Trifocal IOL using diffraction |
CA2883712A1 (en) | 2012-08-31 | 2014-03-06 | Amo Groningen B.V. | Multi-ring lens, systems and methods for extended depth of focus |
CN104755997B (zh) * | 2012-10-23 | 2016-11-16 | 埃西勒国际通用光学公司 | 包括多焦点衍射镜片组件的系统 |
WO2014111831A1 (en) | 2013-01-15 | 2014-07-24 | Dave, Jagrat Natavar | Toric-diffractive lens |
ES2660306T3 (es) * | 2015-10-02 | 2018-03-21 | Rayner Intraocular Lenses Limited | Lente multifocal y procedimiento para su fabricación |
CA3013858A1 (en) | 2016-02-09 | 2017-08-17 | Amo Groningen B.V. | Progressive power intraocular lens, and methods of use and manufacture |
US11083566B2 (en) | 2016-02-29 | 2021-08-10 | Alcon Inc. | Ophthalmic lens having an extended depth of focus |
US20200038172A1 (en) | 2017-02-14 | 2020-02-06 | Jagrat Natavar DAVE | Diffractive multifocal implantable lens device |
US11497599B2 (en) | 2017-03-17 | 2022-11-15 | Amo Groningen B.V. | Diffractive intraocular lenses for extended range of vision |
US11523897B2 (en) | 2017-06-23 | 2022-12-13 | Amo Groningen B.V. | Intraocular lenses for presbyopia treatment |
US11262598B2 (en) | 2017-06-28 | 2022-03-01 | Amo Groningen, B.V. | Diffractive lenses and related intraocular lenses for presbyopia treatment |
CA3068351A1 (en) | 2017-06-28 | 2019-01-03 | Amo Groningen B.V. | Extended range and related intraocular lenses for presbyopia treatment |
US11327210B2 (en) | 2017-06-30 | 2022-05-10 | Amo Groningen B.V. | Non-repeating echelettes and related intraocular lenses for presbyopia treatment |
JP7249322B2 (ja) | 2017-07-24 | 2023-03-30 | アルコン インコーポレイティド | モーフィングされた正弦波位相シフト構造を有する眼用レンズ |
US11378818B2 (en) | 2018-03-01 | 2022-07-05 | Essilor International | Lens element |
US20210048689A1 (en) | 2018-03-01 | 2021-02-18 | Essilor International | Lens element |
US11106056B2 (en) | 2019-03-28 | 2021-08-31 | Aizhong Zhang | Subzonal multifocal diffractive lens |
CN115380239A (zh) | 2019-12-30 | 2022-11-22 | 阿莫格罗宁根私营有限公司 | 用于视力治疗的具有不规则宽度的衍射轮廓的镜片 |
CA3183684A1 (en) | 2020-06-01 | 2021-12-08 | Icares Medicus, Inc. | Double-sided aspheric diffractive multifocal lens, manufacture, and uses thereof |
EP4200665A1 (en) | 2020-08-21 | 2023-06-28 | VSY Biyoteknoloji Ve Ilac Sanayi Anonim Sirketi | A zonal diffractive ocular lens |
WO2022039682A1 (en) | 2020-08-21 | 2022-02-24 | Vsy Biyoteknoloji Ve Ilac Sanayi A.S. | A zonal diffractive ocular lens |
JP2024515002A (ja) | 2021-02-19 | 2024-04-04 | ヴェセイェ・ビヨテクノロジ・ヴェ・イラチ・サナイ・アノニム・シルケティ | 適応多焦点回折眼科レンズ |
CN113331994B (zh) * | 2021-07-29 | 2021-12-07 | 微创视神医疗科技(上海)有限公司 | 人工晶状体 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1115934A (en) * | 1965-09-10 | 1968-06-06 | Zeiss Jena Veb Carl | Spherically corrected fresnel lenses and mirrors with partial field correction |
US4016416A (en) * | 1976-03-23 | 1977-04-05 | The United States Of America As Represented By The Secretary Of The Air Force | Phase compensated zone plate photodetector |
US4210391A (en) * | 1977-09-14 | 1980-07-01 | Cohen Allen L | Multifocal zone plate |
US4338005A (en) * | 1978-12-18 | 1982-07-06 | Cohen Allen L | Multifocal phase place |
US4340283A (en) * | 1978-12-18 | 1982-07-20 | Cohen Allen L | Phase shift multifocal zone plate |
EP0109753B1 (en) * | 1982-10-27 | 1988-07-27 | Pilkington Plc | Bifocal contact lens comprising a plurality of concentric zones |
NL8402324A (nl) * | 1984-07-23 | 1986-02-17 | Visser Contactlenzenpraktijk B | Trifocale contactlens. |
-
1986
- 1986-05-14 US US06/863,069 patent/US5017000A/en not_active Expired - Fee Related
-
1988
- 1988-11-10 CA CA000582735A patent/CA1318799C/en not_active Expired - Fee Related
- 1988-11-10 AT AT88310561T patent/ATE126900T1/de not_active IP Right Cessation
- 1988-11-10 ES ES88310561T patent/ES2075836T3/es not_active Expired - Lifetime
- 1988-11-10 AU AU25020/88A patent/AU623343B2/en not_active Ceased
- 1988-11-10 EP EP88310561A patent/EP0367878B1/en not_active Expired - Lifetime
- 1988-11-10 DE DE3854350T patent/DE3854350T2/de not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
DE3854350T2 (de) | 1996-02-08 |
AU2502088A (en) | 1990-05-17 |
EP0367878B1 (en) | 1995-08-23 |
EP0367878A1 (en) | 1990-05-16 |
AU623343B2 (en) | 1992-05-14 |
CA1318799C (en) | 1993-06-08 |
DE3854350D1 (de) | 1995-09-28 |
ATE126900T1 (de) | 1995-09-15 |
US5017000A (en) | 1991-05-21 |
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