ES2075727T3 - Subunidades-beta neuronales humanas de canales de calcio dependientes de la tension y su uso. - Google Patents

Subunidades-beta neuronales humanas de canales de calcio dependientes de la tension y su uso.

Info

Publication number
ES2075727T3
ES2075727T3 ES93101719T ES93101719T ES2075727T3 ES 2075727 T3 ES2075727 T3 ES 2075727T3 ES 93101719 T ES93101719 T ES 93101719T ES 93101719 T ES93101719 T ES 93101719T ES 2075727 T3 ES2075727 T3 ES 2075727T3
Authority
ES
Spain
Prior art keywords
calcium channels
voltage
human neural
beta subunits
channels dependent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES93101719T
Other languages
English (en)
Other versions
ES2075727T5 (es
Inventor
Peter Dr Spreyer
Axel Dr Unterbeck
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25911933&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2075727(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bayer AG filed Critical Bayer AG
Application granted granted Critical
Publication of ES2075727T3 publication Critical patent/ES2075727T3/es
Publication of ES2075727T5 publication Critical patent/ES2075727T5/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Feedback Control In General (AREA)
  • Electrotherapy Devices (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Measurement Of Current Or Voltage (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

LA INVENCION SE REFIERE A CANALES DE CALCIO DEPENDIENTES DE LA TENSION EN SUBUNIDADES BETA NEURONALES HUMANAS Y SU UTILIZACION EN PROCESOS SCREENING PARA EL HALLAZGO DE MEDICAMENTOS, QUE MODULAN LA ACTIVIDAD DE ESTOS CANALES DE CALCIO.
ES93101719T 1992-02-17 1993-02-04 Subunidades-beta neuronales humanas de canales de calcio dependientes de la tension y su uso. Expired - Lifetime ES2075727T5 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4204716 1992-02-17
DE4222126A DE4222126A1 (de) 1992-02-17 1992-07-06 Humane neuronale beta-untereinheiten spannungsabhaengiger calciumkanaele und deren verwendung

Publications (2)

Publication Number Publication Date
ES2075727T3 true ES2075727T3 (es) 1995-10-01
ES2075727T5 ES2075727T5 (es) 2000-03-01

Family

ID=25911933

Family Applications (1)

Application Number Title Priority Date Filing Date
ES93101719T Expired - Lifetime ES2075727T5 (es) 1992-02-17 1993-02-04 Subunidades-beta neuronales humanas de canales de calcio dependientes de la tension y su uso.

Country Status (9)

Country Link
US (1) US5643750A (es)
EP (1) EP0556651B2 (es)
JP (1) JPH0678773A (es)
AT (1) ATE124723T1 (es)
CA (1) CA2085502A1 (es)
DE (2) DE4222126A1 (es)
DK (1) DK0556651T4 (es)
ES (1) ES2075727T5 (es)
GR (2) GR3017001T3 (es)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5846757A (en) * 1988-04-04 1998-12-08 Sibia Neurosciences, Inc. Human calcium channel α1, α2, and β subunits and assays using them
US5429921A (en) * 1988-04-04 1995-07-04 The Salk Institute Biotechnology/Industrial Assoc. Inc. Assays for agonists and antagonists of recombinant human calcium channels
US6653097B1 (en) 1991-08-15 2003-11-25 Merck & Co., Inc. Human calcium channel compositions and methods
US5874236A (en) * 1988-04-04 1999-02-23 Sibia Neurosciences. Inc. DNA encoding human calcium channel α-1A, β1, β-2, and β-4 subunits, and assays using cells that express the subunits
US5407820A (en) * 1988-04-04 1995-04-18 The Salk Institute Biotechnology/Industrial Associates, Inc. Calcium channel α-2 subunit DNAs and cells expressing them
US5386025A (en) * 1990-02-20 1995-01-31 The Salk Institute Biotechnology/Industrial Associates Calcium channel compositions and methods
US6096514A (en) * 1988-04-04 2000-08-01 Sibia Neurosciences, Inc. Human calcium channel compositions and methods
US20040018510A1 (en) 1990-11-08 2004-01-29 Merck & Co., Inc. Human calcium channel compositions and methods
US6387696B1 (en) 1988-04-04 2002-05-14 Merck & Co., Inc. Human calcium channel compositions and methods
US5851824A (en) * 1988-04-04 1998-12-22 Sibia Neurosciences, Inc. Human calcium channel α-1C/α-1D, α-2, β-1, and γsubunits and cells expressing the DNA
ATE139542T1 (de) 1988-04-04 1996-07-15 Salk Inst Biotech Ind Calciumkanal-zusammensetzungen und verfahren
US5876958A (en) * 1988-04-04 1999-03-02 Sibia Neurosciences, Inc. Assays of cells expressing human calcium channels containing α1 β subunits
US5670113A (en) 1991-12-20 1997-09-23 Sibia Neurosciences, Inc. Automated analysis equipment and assay method for detecting cell surface protein and/or cytoplasmic receptor function using same
US6090623A (en) * 1993-08-11 2000-07-18 Merck & Co., Inc. Recombinant human calcium channel β4 subunits
AU4964896A (en) 1995-01-19 1996-08-07 Research Foundation Of The State University Of New York, The Genes encoding an insect calcium channel
US5712158A (en) * 1995-06-06 1998-01-27 Warner-Lambert Company Cell line for the rapid expression of functional calcium channels
US6040436A (en) * 1996-09-16 2000-03-21 American Home Products Corporation Nucleic acid encoding human neuronal calcium channel subunits
US6528630B1 (en) 1997-12-03 2003-03-04 Merck & Co., Inc. Calcium channel compositions and methods
WO1999063078A2 (en) 1998-06-02 1999-12-09 University Technologies International Inc. Retinal calcium channel (alpha)1f-subunit gene
US6365337B1 (en) 1998-07-27 2002-04-02 University Of Iowa Research Foundation Genes encoding neuronal voltage-gated calcium channel gamma subunits
US20030180712A1 (en) 2002-03-20 2003-09-25 Biostratum Ab Inhibition of the beta3 subunit of L-type Ca2+ channels
US20080248040A1 (en) * 2003-10-02 2008-10-09 Menghang Xia Nucleic Acid Molecules Encoding Novel Human Low-Voltage Activated Calcium Channel Proteins, Designed-Alpha 1I-1 and Alpha 1I-2, Encoded Proteins and Methods of Use Thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4950739A (en) * 1988-02-10 1990-08-21 New York University Membrane calcium channels and factors and methods for blocking, isolating and purifying calcium channels
US5386025A (en) * 1990-02-20 1995-01-31 The Salk Institute Biotechnology/Industrial Associates Calcium channel compositions and methods
US5429921A (en) * 1988-04-04 1995-07-04 The Salk Institute Biotechnology/Industrial Assoc. Inc. Assays for agonists and antagonists of recombinant human calcium channels

Also Published As

Publication number Publication date
GR3032507T3 (en) 2000-05-31
ES2075727T5 (es) 2000-03-01
EP0556651A3 (en) 1993-12-01
CA2085502A1 (en) 1993-08-18
JPH0678773A (ja) 1994-03-22
ATE124723T1 (de) 1995-07-15
DE59300318D1 (de) 1995-08-10
DK0556651T3 (da) 1995-11-06
GR3017001T3 (en) 1995-11-30
EP0556651B2 (de) 1999-11-03
DE4222126A1 (de) 1993-08-19
EP0556651B1 (de) 1995-07-05
EP0556651A2 (de) 1993-08-25
DK0556651T4 (da) 2000-01-17
US5643750A (en) 1997-07-01

Similar Documents

Publication Publication Date Title
ES2075727T5 (es) Subunidades-beta neuronales humanas de canales de calcio dependientes de la tension y su uso.
DE69319185D1 (de) Gemeinsame quelle und detektor und davon gebrauch machende vorrichtung
DE69629988D1 (de) Pharmazeutisches Grundbestandteil und seine Verwendung
DE59610095D1 (de) Dialkyl-halogenphenylsubstituierte ketoenole zur verwendung als herbizide und pestizide
DE122009000052I2 (de) N-((1,2,4)triazoloazinyl)benzolsulfonamid- und pyridinsulfonamidverbindungen und deren verwendung als herbizide
DE69306215D1 (de) Klare, auf dem Haar verbleibende Zusammensetzung zur Pflege der Haare und Verfahren zur Verwendung
DE69308967D1 (de) Elektrophotographische Arbeitseinheit und Bilderzeugungsgerät zur Benutzung der Arbeitseinheit
DE69622148D1 (de) Chinazozin derivate und deren verwendung
DE69015952D1 (de) Spiegeleinrichtung für den Bereich der UV- und Röntgenstrahlen.
DE68921469D1 (de) Peptidderivate und deren verwendung.
ATE77619T1 (de) 3-aryluracile und deren verwendung zur unkrautbekaempfung.
DE69620270D1 (de) Backfett und dessen Verwendung
DE69223266D1 (de) Peptidderivate und deren Verwendung
DE69312633D1 (de) Elektrophotographisches, lichtempfindliches Element und elektrophotographischer Apparat unter Verwendung desselben
DE69804659D1 (de) 21-hydro-6,19-oxidoprogesterone (21oh-60p) und deren verwendung als arzneimittel zur behandlung von glukokortikoidüberschuss
DE69230654D1 (de) Commiphora-Mukul-Extrakte und deren therapeutische Verwendung
DE68910113D1 (de) Wachstuminhibierendes mittel und dessen verwendung.
DE69306377D1 (de) Schallabschirmwand und deren verwendung
DE59610263D1 (de) Kosmetische und/oder pharmazeutische Emulsionen
AT385394B (de) Stabilisierte insektizide mittel und deren verwendung
ATE42462T1 (de) Licht- und sonnenschutzmittel.
DE68916099D1 (de) Vorrichtungen und Mittel zur auswendigen Anwendung von Substanzen an Tieren.
DE69418931D1 (de) Verwendung von VIP und deren Analogen und Fragmenten zur Behandlung von neurodegenerativen Krankheiten
DE59607760D1 (de) Kosmetische und/oder pharmazeutische Emulsionen
DE59608494D1 (de) Kosmetische und/oder pharmazeutische Emulsionen

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 556651

Country of ref document: ES