ES2067395A1 - Nucleoside derivatives or nucleoside analogues - Google Patents
Nucleoside derivatives or nucleoside analoguesInfo
- Publication number
- ES2067395A1 ES2067395A1 ES09300478A ES9300478A ES2067395A1 ES 2067395 A1 ES2067395 A1 ES 2067395A1 ES 09300478 A ES09300478 A ES 09300478A ES 9300478 A ES9300478 A ES 9300478A ES 2067395 A1 ES2067395 A1 ES 2067395A1
- Authority
- ES
- Spain
- Prior art keywords
- nucleoside
- derivatives
- analogues
- hydroxyl group
- compositions
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Nucleoside derivatives or nucleoside analogues which comprise a nitrogen-containing base selected from adenine, guanine, cytosine, uracyl and thymine, and which have the general formula I: Nu-O-Fa in which O represents an oxygen atom, Nu is a nucleoside or nucleoside analogue and Fa is an acyl group of a mono-unsaturated C18 to C20 fatty acid, esterified with a hydroxyl group in position 5 of the sugar residue of the nucleoside or with a hydroxyl group of the non-cyclic chain of the nucleoside analogue. Also described are pharmaceutical and veterinary antiviral compositions which include a compound of formula I alone or in combination with a pharmaceutically acceptable vehicle. These derivatives and compositions are useful for treating a human or animal patient suffering from a viral infection and for reducing the infection level.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES9300478A ES2067395B1 (en) | 1993-03-10 | 1993-03-10 | DERIVATIVES OF NUCLEOSIDES OR ANALOGS TO NUCLEOSIDES. |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES9300478A ES2067395B1 (en) | 1993-03-10 | 1993-03-10 | DERIVATIVES OF NUCLEOSIDES OR ANALOGS TO NUCLEOSIDES. |
Publications (2)
Publication Number | Publication Date |
---|---|
ES2067395A1 true ES2067395A1 (en) | 1995-03-16 |
ES2067395B1 ES2067395B1 (en) | 1996-01-01 |
Family
ID=8281044
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES9300478A Expired - Fee Related ES2067395B1 (en) | 1993-03-10 | 1993-03-10 | DERIVATIVES OF NUCLEOSIDES OR ANALOGS TO NUCLEOSIDES. |
Country Status (1)
Country | Link |
---|---|
ES (1) | ES2067395B1 (en) |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0056265A2 (en) * | 1981-01-09 | 1982-07-21 | Dr. Thilo & Co. GmbH | Pyrimidinenucleosides esterified in position 5' having antiviral activity, method for their preparation and medicinal compositions containing them |
WO1988007532A1 (en) * | 1987-03-24 | 1988-10-06 | Nycomed A.S. | 2',3' dideoxyribofuranoxide derivatives |
EP0350287A2 (en) * | 1988-07-07 | 1990-01-10 | NeXstar Pharmaceuticals, Inc. | Lipid derivatives of antiviral nucleosides, liposomal incorporation and method of use |
-
1993
- 1993-03-10 ES ES9300478A patent/ES2067395B1/en not_active Expired - Fee Related
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0056265A2 (en) * | 1981-01-09 | 1982-07-21 | Dr. Thilo & Co. GmbH | Pyrimidinenucleosides esterified in position 5' having antiviral activity, method for their preparation and medicinal compositions containing them |
WO1988007532A1 (en) * | 1987-03-24 | 1988-10-06 | Nycomed A.S. | 2',3' dideoxyribofuranoxide derivatives |
EP0350287A2 (en) * | 1988-07-07 | 1990-01-10 | NeXstar Pharmaceuticals, Inc. | Lipid derivatives of antiviral nucleosides, liposomal incorporation and method of use |
Also Published As
Publication number | Publication date |
---|---|
ES2067395B1 (en) | 1996-01-01 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD2A | Announcement of lapse in spain |
Effective date: 20141120 |