ES2067395A1 - Nucleoside derivatives or nucleoside analogues - Google Patents

Nucleoside derivatives or nucleoside analogues

Info

Publication number
ES2067395A1
ES2067395A1 ES09300478A ES9300478A ES2067395A1 ES 2067395 A1 ES2067395 A1 ES 2067395A1 ES 09300478 A ES09300478 A ES 09300478A ES 9300478 A ES9300478 A ES 9300478A ES 2067395 A1 ES2067395 A1 ES 2067395A1
Authority
ES
Spain
Prior art keywords
nucleoside
derivatives
analogues
hydroxyl group
compositions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES09300478A
Other languages
Spanish (es)
Other versions
ES2067395B1 (en
Inventor
Are Dalen
Finn Myhren
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Norsk Hydro ASA
Original Assignee
Norsk Hydro ASA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Norsk Hydro ASA filed Critical Norsk Hydro ASA
Priority to ES9300478A priority Critical patent/ES2067395B1/en
Publication of ES2067395A1 publication Critical patent/ES2067395A1/en
Application granted granted Critical
Publication of ES2067395B1 publication Critical patent/ES2067395B1/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Abstract

Nucleoside derivatives or nucleoside analogues which comprise a nitrogen-containing base selected from adenine, guanine, cytosine, uracyl and thymine, and which have the general formula I: Nu-O-Fa in which O represents an oxygen atom, Nu is a nucleoside or nucleoside analogue and Fa is an acyl group of a mono-unsaturated C18 to C20 fatty acid, esterified with a hydroxyl group in position 5 of the sugar residue of the nucleoside or with a hydroxyl group of the non-cyclic chain of the nucleoside analogue. Also described are pharmaceutical and veterinary antiviral compositions which include a compound of formula I alone or in combination with a pharmaceutically acceptable vehicle. These derivatives and compositions are useful for treating a human or animal patient suffering from a viral infection and for reducing the infection level.
ES9300478A 1993-03-10 1993-03-10 DERIVATIVES OF NUCLEOSIDES OR ANALOGS TO NUCLEOSIDES. Expired - Fee Related ES2067395B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
ES9300478A ES2067395B1 (en) 1993-03-10 1993-03-10 DERIVATIVES OF NUCLEOSIDES OR ANALOGS TO NUCLEOSIDES.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES9300478A ES2067395B1 (en) 1993-03-10 1993-03-10 DERIVATIVES OF NUCLEOSIDES OR ANALOGS TO NUCLEOSIDES.

Publications (2)

Publication Number Publication Date
ES2067395A1 true ES2067395A1 (en) 1995-03-16
ES2067395B1 ES2067395B1 (en) 1996-01-01

Family

ID=8281044

Family Applications (1)

Application Number Title Priority Date Filing Date
ES9300478A Expired - Fee Related ES2067395B1 (en) 1993-03-10 1993-03-10 DERIVATIVES OF NUCLEOSIDES OR ANALOGS TO NUCLEOSIDES.

Country Status (1)

Country Link
ES (1) ES2067395B1 (en)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0056265A2 (en) * 1981-01-09 1982-07-21 Dr. Thilo & Co. GmbH Pyrimidinenucleosides esterified in position 5' having antiviral activity, method for their preparation and medicinal compositions containing them
WO1988007532A1 (en) * 1987-03-24 1988-10-06 Nycomed A.S. 2',3' dideoxyribofuranoxide derivatives
EP0350287A2 (en) * 1988-07-07 1990-01-10 NeXstar Pharmaceuticals, Inc. Lipid derivatives of antiviral nucleosides, liposomal incorporation and method of use

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0056265A2 (en) * 1981-01-09 1982-07-21 Dr. Thilo & Co. GmbH Pyrimidinenucleosides esterified in position 5' having antiviral activity, method for their preparation and medicinal compositions containing them
WO1988007532A1 (en) * 1987-03-24 1988-10-06 Nycomed A.S. 2',3' dideoxyribofuranoxide derivatives
EP0350287A2 (en) * 1988-07-07 1990-01-10 NeXstar Pharmaceuticals, Inc. Lipid derivatives of antiviral nucleosides, liposomal incorporation and method of use

Also Published As

Publication number Publication date
ES2067395B1 (en) 1996-01-01

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Legal Events

Date Code Title Description
FD2A Announcement of lapse in spain

Effective date: 20141120