ES2066733A1 - Complejo consistente en un activador del plasminogeno y albumina de suero y procedimiento para prepararlo. - Google Patents

Complejo consistente en un activador del plasminogeno y albumina de suero y procedimiento para prepararlo.

Info

Publication number
ES2066733A1
ES2066733A1 ES09301466A ES9301466A ES2066733A1 ES 2066733 A1 ES2066733 A1 ES 2066733A1 ES 09301466 A ES09301466 A ES 09301466A ES 9301466 A ES9301466 A ES 9301466A ES 2066733 A1 ES2066733 A1 ES 2066733A1
Authority
ES
Spain
Prior art keywords
serum albumin
procedure
plasminogen
activator
preparing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES09301466A
Other languages
English (en)
Other versions
ES2066733B1 (es
Inventor
Bravo Juan Ignacio Prieto
De Buitrago Y Arriero Gonzalez
Jerome Breton
Antonio Milinari
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmacia Antibioticos Farma SA
Original Assignee
Antibioticos Farma SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Antibioticos Farma SA filed Critical Antibioticos Farma SA
Priority to ES9301466A priority Critical patent/ES2066733B1/es
Publication of ES2066733A1 publication Critical patent/ES2066733A1/es
Application granted granted Critical
Publication of ES2066733B1 publication Critical patent/ES2066733B1/es
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Landscapes

  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

COMPLEJO CONSISTENTE EN UN ACTIVADOR DEL PLASMINOGENO Y ALBUMINA DE SUERO, Y PROCEDIMIENTO PARA PREPARARLO. DICHO COMPLEJO CONSISTE EN (A) UN DERIVADO DE PROUROQUINASA HUMANA QUE CARECE DEL DOMINIO ANALOGO AL DEL FACTOR DE CRECIMIENTO EPIDERMICO Y DEL DOMINIO TIPO KRINGLE Y QUE POSEE UN RESIDUO DE CISTEINA NO COMPROMETIDO EN UN PUENTE DISULFURO INTRAMOLECULAR; Y (B) SEROALBUMINA HUMANA UNIDA AL MISMO A TRAVES DE DICHO RESIDUO DE CISTEINA; COMPRENDIENDO DICHO PROCEDIMIENTO CONJUGAR EL DERIVADO DE PROUROQUINASA HUMANA CON SEROALBUMINA HUMANA. DICHO COMPLEJO ES UTIL EN EL TRATAMIENTO DE LAS CARDIOPATIAS.
ES9301466A 1993-06-30 1993-06-30 Complejo consistente en un activador del plasminogeno y albumina de suero y procedimiento para prepararlo. Expired - Fee Related ES2066733B1 (es)

Priority Applications (1)

Application Number Priority Date Filing Date Title
ES9301466A ES2066733B1 (es) 1993-06-30 1993-06-30 Complejo consistente en un activador del plasminogeno y albumina de suero y procedimiento para prepararlo.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES9301466A ES2066733B1 (es) 1993-06-30 1993-06-30 Complejo consistente en un activador del plasminogeno y albumina de suero y procedimiento para prepararlo.

Publications (2)

Publication Number Publication Date
ES2066733A1 true ES2066733A1 (es) 1995-03-01
ES2066733B1 ES2066733B1 (es) 1995-11-01

Family

ID=8282395

Family Applications (1)

Application Number Title Priority Date Filing Date
ES9301466A Expired - Fee Related ES2066733B1 (es) 1993-06-30 1993-06-30 Complejo consistente en un activador del plasminogeno y albumina de suero y procedimiento para prepararlo.

Country Status (1)

Country Link
ES (1) ES2066733B1 (es)

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0152736A2 (en) * 1984-01-11 1985-08-28 Beecham Group Plc Enzyme-protein conjugate, process for its preparation and pharmaceutical composition
EP0395918A2 (en) * 1989-04-13 1990-11-07 Vascular Laboratory, Inc. Plasminogen activator complex of pure pro-urokinase covalently bound by a disulfide bridge to human serum albumin
EP0541952A1 (en) * 1991-10-07 1993-05-19 The Green Cross Corporation Mutant human prourokinase
JPH09175883A (ja) * 1995-12-26 1997-07-08 Shin Etsu Handotai Co Ltd 単結晶引上装置

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0152736A2 (en) * 1984-01-11 1985-08-28 Beecham Group Plc Enzyme-protein conjugate, process for its preparation and pharmaceutical composition
EP0395918A2 (en) * 1989-04-13 1990-11-07 Vascular Laboratory, Inc. Plasminogen activator complex of pure pro-urokinase covalently bound by a disulfide bridge to human serum albumin
EP0541952A1 (en) * 1991-10-07 1993-05-19 The Green Cross Corporation Mutant human prourokinase
JPH09175883A (ja) * 1995-12-26 1997-07-08 Shin Etsu Handotai Co Ltd 単結晶引上装置

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
BASE DE DATOS WPIL, 84-285291, 1984, Derwent Publications Ltd., London, GB & JP-A-9175883 (WAKAMOTO PHARM KK) 4-Octubre-1984 * Resumen * *

Also Published As

Publication number Publication date
ES2066733B1 (es) 1995-11-01

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Legal Events

Date Code Title Description
PC2A Transfer of patent

Owner name: PHARMACIA ANTIBIOTICOS FARMA, S.A.

FD1A Patent lapsed

Effective date: 19990301