ES2065290A1 - Utilizacion de inhibidores enzimaticos para el tratamiento de enfermedades causadas por parasitos. - Google Patents

Utilizacion de inhibidores enzimaticos para el tratamiento de enfermedades causadas por parasitos.

Info

Publication number
ES2065290A1
ES2065290A1 ES09301714A ES9301714A ES2065290A1 ES 2065290 A1 ES2065290 A1 ES 2065290A1 ES 09301714 A ES09301714 A ES 09301714A ES 9301714 A ES9301714 A ES 9301714A ES 2065290 A1 ES2065290 A1 ES 2065290A1
Authority
ES
Spain
Prior art keywords
treatment
parasites
inhibitors
enzymatic activity
diseases caused
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES09301714A
Other languages
English (en)
Other versions
ES2065290B1 (es
Inventor
Aguilar Antonio Gonzalez
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Consejo Superior de Investigaciones Cientificas CSIC
Original Assignee
Consejo Superior de Investigaciones Cientificas CSIC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Consejo Superior de Investigaciones Cientificas CSIC filed Critical Consejo Superior de Investigaciones Cientificas CSIC
Priority to ES09301714A priority Critical patent/ES2065290B1/es
Publication of ES2065290A1 publication Critical patent/ES2065290A1/es
Application granted granted Critical
Publication of ES2065290B1 publication Critical patent/ES2065290B1/es
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

UTILIZACION DE INHIBIDORES ENZIMATICOS PARA EL TRATAMIENTO DE ENFERMEDADES CAUSADAS POR PARASITOS. EL OBJETO DE LA INVENCION ES LA UTILIZACION DE CIERTOS INHIBIDORES DE UNA DETERMINADA ACTIVIDAD ENZIMATICA PARA EL TRATAMIENTO DE ENFERMEDADES PRODUCIDAS POR EL PROTOZOO PARASITO TRYPANOSOMA CRUZI O POR LOS PARASITOS BACTERIANOS CHLAMYDIA SP. Y LEGIONELLA SP. SE PARTE DE HABER ENCONTRADO QUE ESTOS PARASITOS SECRETAN AL MEDIO CIERTAS PROTEINAS INVOLUCRADAS EN EL MECANISMO DE INVASION CELULAR. ESTAS PROTEINAS POSEEN LA ACTIVIDAD ENZIMATICA PEPTIDIL-PROLIL CIS/TRANS ISOMERASA DEL TIPO FKBP. EL BLOQUEO DE DICHA ACTIVIDAD ENZIMATICA MEDIANTE INHIBIDORES ESPECIFICOS CONDUCE A DIFICULTAR LA CAPACIDAD INFECTIVA DE LOS MICROORGANISMOS Y SU SUPERVIVENCIA EN EL HUESPED. EL EMPLEO DE LOS MENCIONADOS INHIBIDORES PUEDE SER DE INTERES EN LA PREPARACION DE FORMULACIONES FARMACEUTICAS ADECUADAS PARA EL TRATAMIENTO DE LAENFERMEDAD DE CHAGAS, LA CLAMIDIASIS O LA NEUMONIA ATIPICA DEL LEGIONARIO.
ES09301714A 1993-07-29 1993-07-29 Utilizacion de inhibidores enzimaticos para el tratamiento de enfermedades causadas por parasitos. Expired - Fee Related ES2065290B1 (es)

Priority Applications (1)

Application Number Priority Date Filing Date Title
ES09301714A ES2065290B1 (es) 1993-07-29 1993-07-29 Utilizacion de inhibidores enzimaticos para el tratamiento de enfermedades causadas por parasitos.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES09301714A ES2065290B1 (es) 1993-07-29 1993-07-29 Utilizacion de inhibidores enzimaticos para el tratamiento de enfermedades causadas por parasitos.

Publications (2)

Publication Number Publication Date
ES2065290A1 true ES2065290A1 (es) 1995-02-01
ES2065290B1 ES2065290B1 (es) 1995-11-01

Family

ID=8282732

Family Applications (1)

Application Number Title Priority Date Filing Date
ES09301714A Expired - Fee Related ES2065290B1 (es) 1993-07-29 1993-07-29 Utilizacion de inhibidores enzimaticos para el tratamiento de enfermedades causadas por parasitos.

Country Status (1)

Country Link
ES (1) ES2065290B1 (es)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1567864A2 (en) * 2002-11-22 2005-08-31 Wyeth Composition for treating chlamydia infections and method for identifying same

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992000278A1 (en) * 1990-07-02 1992-01-09 Vertex Pharmaceuticals Incorporated Novel immunosuppressive compounds
WO1992006992A2 (en) * 1990-10-09 1992-04-30 Merck & Co., Inc. New process for biophosphorylating organic compounds

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992000278A1 (en) * 1990-07-02 1992-01-09 Vertex Pharmaceuticals Incorporated Novel immunosuppressive compounds
WO1992006992A2 (en) * 1990-10-09 1992-04-30 Merck & Co., Inc. New process for biophosphorylating organic compounds

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
JOURNAL OF EXPERIMENTAL MEDICINE, vol. 176, septiembre 1992, USA F.J. DUMONT et al.: "The immunosupressive and toxic effects of FK-506 are mechanistically related: pharmacology of a novel antagonist of FK-506 and rapamycin", pßgs.: 751-760. *
THE JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 268, n‘ 15, mayo 1993, USA J.W. BECKER et al.: "FK-506-binding protein: three-dimensional structure of the complex with the antagonist l-685.818", pßgs.: 11335-11339. *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1567864A2 (en) * 2002-11-22 2005-08-31 Wyeth Composition for treating chlamydia infections and method for identifying same
EP1567864A4 (en) * 2002-11-22 2007-01-03 Wyeth Corp COMPOSITION FOR THE TREATMENT OF CHLAMYDIA INFECTIONS AND METHOD FOR THE IDENTIFICATION THEREOF

Also Published As

Publication number Publication date
ES2065290B1 (es) 1995-11-01

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20040730