ES2057542T3 - Agentes terapeuticos. - Google Patents

Agentes terapeuticos.

Info

Publication number
ES2057542T3
ES2057542T3 ES90904349T ES90904349T ES2057542T3 ES 2057542 T3 ES2057542 T3 ES 2057542T3 ES 90904349 T ES90904349 T ES 90904349T ES 90904349 T ES90904349 T ES 90904349T ES 2057542 T3 ES2057542 T3 ES 2057542T3
Authority
ES
Spain
Prior art keywords
formula
compound
ace
inhibitor
methyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES90904349T
Other languages
English (en)
Inventor
Patrick Coleman O'connor
Charles Leon-Marie Defesche
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boots Co PLC
Original Assignee
Boots Co PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boots Co PLC filed Critical Boots Co PLC
Application granted granted Critical
Publication of ES2057542T3 publication Critical patent/ES2057542T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Epidemiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Steroid Compounds (AREA)

Abstract

UN PRODUCTO QUE CONTIENE UNA CANTIDAD TERAPEUTICAMENTE EFICAZ DE UN INHIBIDOR DEL ENZIMA CONVERSOR DE ANGIOTENSINA (ACE) Y UNA CANTIDAD TERAPEUTICAMENTE EFICAZ DE UN COMPUESTO CON LA FORMULA (I), EN DONDE N TIENE UN VALOR DE 1 O 2. EL COMPUESTO PREFERIDO DE LA FORMULA (I) ES 7 - FLUORO - 1 - METIL - 3 - SULFINIL - 4 QUINILONA. SE PUEDEN ADMINISTRAR EL COMPUESTO DE LA FORMULA (I) Y EL INHIBIDOR DE ACE CONCOMITANTE O CONCURRENTEMENTE Y SE DESCRIBEN PREPARACIONES COMBINADAS PARA USO SIMULTANEO, SEPARADO O SECUENCIAL. LA ADMINISTRACION CONCOMITANTE SE PUEDE REALIZAR MEDIANTE COMPOSICIONES FARMACEUTICAS NUEVAS QUE COMPRENDEN UN COMPUESTO CON LA FORMULA (I), UN INHIBIDOR DE ACE Y UN PORTADOR FARMACEUTICAMENTE ACEPTABLE.
ES90904349T 1989-03-15 1990-03-12 Agentes terapeuticos. Expired - Lifetime ES2057542T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US32421389A 1989-03-15 1989-03-15

Publications (1)

Publication Number Publication Date
ES2057542T3 true ES2057542T3 (es) 1994-10-16

Family

ID=23262607

Family Applications (1)

Application Number Title Priority Date Filing Date
ES90904349T Expired - Lifetime ES2057542T3 (es) 1989-03-15 1990-03-12 Agentes terapeuticos.

Country Status (13)

Country Link
EP (1) EP0527720B1 (es)
JP (1) JPH04503806A (es)
KR (1) KR920700642A (es)
AT (1) ATE109981T1 (es)
AU (1) AU640128B2 (es)
CA (1) CA2049980A1 (es)
DE (1) DE69011692T2 (es)
DK (1) DK0527720T3 (es)
ES (1) ES2057542T3 (es)
IE (1) IE65902B1 (es)
IL (1) IL93744A (es)
WO (1) WO1990010445A1 (es)
ZA (1) ZA901945B (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0651640A1 (en) * 1992-07-21 1995-05-10 Knoll AG Use of 7-fluoro-1-methyl-3-methylsulphinyl-4-quinolone in the treatment of angina pectoris

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3542794A1 (de) * 1985-12-04 1987-06-11 Bayer Ag Antihypertensives kombinationspraeparat

Also Published As

Publication number Publication date
IE900818L (en) 1990-09-15
IL93744A (en) 1995-06-29
KR920700642A (ko) 1992-08-10
DE69011692T2 (de) 1994-12-01
AU640128B2 (en) 1993-08-19
EP0527720B1 (en) 1994-08-17
DE69011692D1 (de) 1994-09-22
EP0527720A1 (en) 1993-02-24
IL93744A0 (en) 1990-12-23
ATE109981T1 (de) 1994-09-15
JPH04503806A (ja) 1992-07-09
WO1990010445A1 (en) 1990-09-20
ZA901945B (en) 1991-01-30
CA2049980A1 (en) 1990-09-16
DK0527720T3 (da) 1994-12-05
AU5261690A (en) 1990-10-09
IE65902B1 (en) 1995-11-29

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