ES2056822T3 - Agentes inmunoestimulantes. - Google Patents
Agentes inmunoestimulantes.Info
- Publication number
- ES2056822T3 ES2056822T3 ES87305911T ES87305911T ES2056822T3 ES 2056822 T3 ES2056822 T3 ES 2056822T3 ES 87305911 T ES87305911 T ES 87305911T ES 87305911 T ES87305911 T ES 87305911T ES 2056822 T3 ES2056822 T3 ES 2056822T3
- Authority
- ES
- Spain
- Prior art keywords
- immuno
- stimulating agents
- dideoxyzearalane
- zearalene
- zearalane
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000003022 immunostimulating agent Substances 0.000 title 1
- FPQFYIAXQDXNOR-QDKLYSGJSA-N alpha-Zearalenol Chemical compound O=C1O[C@@H](C)CCC[C@H](O)CCC\C=C\C2=CC(O)=CC(O)=C21 FPQFYIAXQDXNOR-QDKLYSGJSA-N 0.000 abstract 2
- NPMCCMIBMODCMD-ZDUSSCGKSA-N (11s)-15,17-dihydroxy-11-methyl-12-oxabicyclo[12.4.0]octadeca-1(18),14,16-trien-13-one Chemical compound O=C1O[C@@H](C)CCCCCCCCCC2=CC(O)=CC(O)=C21 NPMCCMIBMODCMD-ZDUSSCGKSA-N 0.000 abstract 1
- QVIMWXDXYFRIEH-HNNXBMFYSA-N O=C1O[C@@H](C)CCCCCCCCCC2=CC=CC=C21 Chemical compound O=C1O[C@@H](C)CCCCCCCCCC2=CC=CC=C21 QVIMWXDXYFRIEH-HNNXBMFYSA-N 0.000 abstract 1
- 241000251539 Vertebrata <Metazoa> Species 0.000 abstract 1
- APJDQUGPCJRQRJ-LBPRGKRZSA-N Zearalanone Chemical compound O=C1O[C@@H](C)CCCC(=O)CCCCCC2=CC(O)=CC(O)=C21 APJDQUGPCJRQRJ-LBPRGKRZSA-N 0.000 abstract 1
- APJDQUGPCJRQRJ-UHFFFAOYSA-N Zearalanone Natural products O=C1OC(C)CCCC(=O)CCCCCC2=CC(O)=CC(O)=C21 APJDQUGPCJRQRJ-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 210000000987 immune system Anatomy 0.000 abstract 1
- 150000002596 lactones Chemical class 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- MBMQEIFVQACCCH-UHFFFAOYSA-N trans-Zearalenon Natural products O=C1OC(C)CCCC(=O)CCCC=CC2=CC(O)=CC(O)=C21 MBMQEIFVQACCCH-UHFFFAOYSA-N 0.000 abstract 1
- -1 zearalene Chemical compound 0.000 abstract 1
- MBMQEIFVQACCCH-QBODLPLBSA-N zearalenone Chemical compound O=C1O[C@@H](C)CCCC(=O)CCC\C=C\C2=CC(O)=CC(O)=C21 MBMQEIFVQACCCH-QBODLPLBSA-N 0.000 abstract 1
- 229960002300 zeranol Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Steroid Compounds (AREA)
Abstract
EL ACIDO RESORCICLICO DE LACTONA (RAL) Y SUS DERIVADOS ZEARALENONA, ZEARALENONA, ZEARALENE, ZEARALANES, ZEARALENOL, ZEARALANOL, DIDEOXIZEARALANE, Y SUS SALES FARMACEUTICAMENTE ACEPTABLES PUEDEN SER ADMINISTRADAS A VERTEBRADOS PARA ESTIMULAR DE UNA FORMA NO ESPECIFICA, AL SISTEMA INMUNOLOGICO.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/881,926 US4842862A (en) | 1986-07-03 | 1986-07-03 | Immunostimulating agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2056822T3 true ES2056822T3 (es) | 1994-10-16 |
Family
ID=25379498
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES87305911T Expired - Lifetime ES2056822T3 (es) | 1986-07-03 | 1987-07-03 | Agentes inmunoestimulantes. |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US4842862A (es) |
| EP (1) | EP0251813B1 (es) |
| AT (1) | ATE90872T1 (es) |
| DE (1) | DE3786304T2 (es) |
| ES (1) | ES2056822T3 (es) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5110794A (en) * | 1987-01-30 | 1992-05-05 | Abbott Laboratories | Method of immunization with partially cationized substances and said partially cationized substances |
| CA1337403C (en) * | 1988-03-28 | 1995-10-24 | Biomembrane Institute (The) | Methods for the production of antibodies and induction of immune responses to tumor-associated gangliosides by immunization with ganglioside lactones |
| EP0477050B1 (en) * | 1990-08-20 | 1997-05-21 | Gen-Ichiro Soma | LPS-producing bacteria, LPSs, and LPS-containing medicines and veterinary medicines |
| US5622649A (en) * | 1991-06-27 | 1997-04-22 | Emory University | Multiple emulsions and methods of preparation |
| ES2183867T3 (es) * | 1994-02-18 | 2003-04-01 | Solidose L L C | Inoculacion de animales con materiales biologicos secados en peletes. |
| US5795910A (en) * | 1994-10-28 | 1998-08-18 | Cor Therapeutics, Inc. | Method and compositions for inhibiting protein kinases |
| JP2002533389A (ja) | 1998-12-24 | 2002-10-08 | ノーベーション ファーマシューティカルズ インコーポレーテッド | mRNA安定性に影響する化合物およびそのための使用 |
| US6528489B1 (en) * | 1999-09-23 | 2003-03-04 | Ergon Pharmaceuticals Llc | Mycotoxin derivatives as antimitotic agents |
| US6716448B2 (en) | 2001-10-05 | 2004-04-06 | Rubicon Scientific Llc | Domesticated household pet food including maintenance amounts of ivermectin |
| US7052712B2 (en) * | 2001-10-05 | 2006-05-30 | Rubicon Scientific Llc | Animal feeds including actives and methods of preparing same |
| US6866862B2 (en) * | 2001-10-05 | 2005-03-15 | Rubicon Scientific | Animal feeds including heartworm-prevention drugs |
| JP2005505280A (ja) * | 2001-10-05 | 2005-02-24 | ルビコン サイエンティフィック エルエルシー | 有効成分を含む動物用飼料および該飼料を用いる方法 |
| US20040091579A1 (en) * | 2002-11-13 | 2004-05-13 | Rubicon Scientific Llc; | Extruded foodstuffs having maintenance level actives |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL131475C (es) * | 1965-02-15 | |||
| US3453367A (en) * | 1966-06-29 | 1969-07-01 | Commercial Solvents Corp | Methods for treating inflammation with estrogenic compounds |
| GB1506563A (en) * | 1974-04-25 | 1978-04-05 | Williams J | Immunosuppressive agents |
| US4173641A (en) * | 1978-05-15 | 1979-11-06 | Pfizer Inc. | Di-O-n-alkyl glycerol derivatives as immune stimulants |
| JPS5513238A (en) * | 1978-07-17 | 1980-01-30 | Banyu Pharmaceut Co Ltd | Novel compound having immunoactivating action, its preparation and application |
| US4281120A (en) * | 1978-12-12 | 1981-07-28 | Siegfried Herrling | 7H-1,3,4-Thiadiazolo-[3,2-a]-pyrimidin-7-one-5-carboxylic compounds |
| US4239772A (en) * | 1979-05-30 | 1980-12-16 | International Minerals & Chemical Corp. | Allyl and propyl zearalenone derivatives and their use as growth promoting agents |
| JPS56127369A (en) * | 1980-02-15 | 1981-10-06 | Mitsui Toatsu Chem Inc | Nevel piperazine compound, its preparation and utilization |
| US4442031A (en) * | 1981-10-15 | 1984-04-10 | Hoffmann-La Roche Inc. | Immunopotentiating peptides |
| FR2515188A1 (fr) * | 1981-10-27 | 1983-04-29 | Roussel Uclaf | Nouveaux derives du 3-amino-pregn-5-ene, leurs sels, procede de preparation, application a titre de medicaments et compositions les renfermant |
| JPS5998015A (ja) * | 1982-11-27 | 1984-06-06 | Microbial Chem Res Found | 免疫賦活剤 |
| US4681760A (en) * | 1985-04-17 | 1987-07-21 | The Board Of Trustees Of The Leland Stanford Junior University | Method of conferring immunotolerance to a specific antigen |
-
1986
- 1986-07-03 US US06/881,926 patent/US4842862A/en not_active Expired - Fee Related
-
1987
- 1987-07-03 ES ES87305911T patent/ES2056822T3/es not_active Expired - Lifetime
- 1987-07-03 DE DE87305911T patent/DE3786304T2/de not_active Expired - Fee Related
- 1987-07-03 AT AT87305911T patent/ATE90872T1/de not_active IP Right Cessation
- 1987-07-03 EP EP87305911A patent/EP0251813B1/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP0251813B1 (en) | 1993-06-23 |
| ATE90872T1 (de) | 1993-07-15 |
| EP0251813A3 (en) | 1990-01-31 |
| US4842862A (en) | 1989-06-27 |
| DE3786304D1 (de) | 1993-07-29 |
| DE3786304T2 (de) | 1993-10-21 |
| EP0251813A2 (en) | 1988-01-07 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
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