ES2056216T3 - Referencia para tecnicas de inmunocoloracion. - Google Patents
Referencia para tecnicas de inmunocoloracion.Info
- Publication number
- ES2056216T3 ES2056216T3 ES89304886T ES89304886T ES2056216T3 ES 2056216 T3 ES2056216 T3 ES 2056216T3 ES 89304886 T ES89304886 T ES 89304886T ES 89304886 T ES89304886 T ES 89304886T ES 2056216 T3 ES2056216 T3 ES 2056216T3
- Authority
- ES
- Spain
- Prior art keywords
- gel
- block
- pellets
- sample
- sections
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 238000000034 method Methods 0.000 title abstract 3
- 239000000499 gel Substances 0.000 abstract 4
- 239000008188 pellet Substances 0.000 abstract 3
- 239000000427 antigen Substances 0.000 abstract 2
- 102000036639 antigens Human genes 0.000 abstract 2
- 108091007433 antigens Proteins 0.000 abstract 2
- 238000012744 immunostaining Methods 0.000 abstract 2
- 229920001817 Agar Polymers 0.000 abstract 1
- 230000002745 absorbent Effects 0.000 abstract 1
- 239000002250 absorbent Substances 0.000 abstract 1
- 230000004888 barrier function Effects 0.000 abstract 1
- 238000009792 diffusion process Methods 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/5436—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals with ligand physically entrapped within the solid phase
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/36—Embedding or analogous mounting of samples
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
- G01N2001/305—Fixative compositions
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2474/00—Immunochemical assays or immunoassays characterised by detection mode or means of detection
- G01N2474/20—Immunohistochemistry assay
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/967—Standards, controls, materials, e.g. validation studies, buffer systems
Landscapes
- Health & Medical Sciences (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Pathology (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Cell Biology (AREA)
- Medicinal Chemistry (AREA)
- Food Science & Technology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Sampling And Sample Adjustment (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
SE PROPORCIONA UN PROCEDIMIENTO Y MATERIAL PARA ENSAYO/CONTROL PARA FACILITAR LA NORMALIZACION DE TECNICAS DE INMUNOTINCION Y LA VALORACION DE SUS RESULTADOS. SE HACE QUE BOLITAS DE UN GEL ADSORBENTE, TAL COMO GEL DE AGAR ADSORBAN CONCENTRACIONES ESPECIFICAS INDIVIDUALES DE UN ANTIGENO DE INTERES. LOS ANTIGENOS ADSORBIDOS ESTAN ENCERRADOS EN LAS BOLITAS INDIVIDUALES COMO POR FIJACION O POR ENCIERRO EN UNA BARRERA DE DIFUSION-INHIBICION, Y LAS BOLITAS SE INSTALAN EN HUECOS INDIVIDUALES EN UN BLOQUE DEL GEL, DE MANERA QUE SE INTEGRAN EN EL. EL BLOQUE SE PUEDE SOMETER LUEGO A LAS MISMAS RUTINAS PREPARATIVAS COMO UNA MUESTRA DE TEJIDO, SECCIONAR Y MONTAR IGUAL QUE LA MUESTRA Y LUEGO SOMETER A INMUNOTINCION MEDIANTE LA MISMA RUTINA QUE LAS SECCIONES DE LA MUESTRA, PARA PROPORCIONAR UNA BASE VALIDA PARA VALORACION DE LAS SECCIONES DE LA MUESTRA TE/IDA POR COMPARACION CON LAS SECCIONES DEL BLOUQE DE GEL TE/IDO. TAMBIEN SE DESCRIBE UN BLOQUE DE GEL DE CONFIGURACION ADECUADA.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB888813628A GB8813628D0 (en) | 1988-06-09 | 1988-06-09 | Immunostaining |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2056216T3 true ES2056216T3 (es) | 1994-10-01 |
Family
ID=10638332
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES89304886T Expired - Lifetime ES2056216T3 (es) | 1988-06-09 | 1989-05-15 | Referencia para tecnicas de inmunocoloracion. |
Country Status (7)
Country | Link |
---|---|
US (1) | US5143714A (es) |
EP (1) | EP0345953B1 (es) |
JP (1) | JPH0232260A (es) |
AT (1) | ATE108554T1 (es) |
DE (1) | DE68916710T2 (es) |
ES (1) | ES2056216T3 (es) |
GB (1) | GB8813628D0 (es) |
Families Citing this family (34)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5610022A (en) * | 1989-09-26 | 1997-03-11 | City Of Hope | Internal control for immunocytochemistry assay |
US5290706A (en) * | 1992-11-10 | 1994-03-01 | Camiener Gerald W | Visualization system for retrieval, identification, and positioning of biological samples for subsequent microscopic examination |
US5965454A (en) * | 1993-02-03 | 1999-10-12 | Histaggen Incorporated | Automated histo-cytochemistry apparatus and encapsulation system for processing biological materials |
ES2119166T3 (es) * | 1993-02-03 | 1998-10-01 | Histaggen Inc | Sistema de encapsulacion y aparato de histocitoquimica automatica destinados al tratamiento de sustancias biologicas. |
AU748061B2 (en) * | 1994-10-18 | 2002-05-30 | Regents Of The University Of California, The | The combinatorial synthesis of novel materials |
US6699710B1 (en) * | 1998-02-25 | 2004-03-02 | The United States Of America As Represented By The Department Of Health And Human Services | Tumor tissue microarrays for rapid molecular profiling |
US20070166834A1 (en) * | 1998-10-05 | 2007-07-19 | Biopath Automation, L.L.C. | Apparatus and method for harvesting and handling tissue samples for biopsy analysis |
CA2347002A1 (en) | 1998-10-21 | 2000-04-27 | Steven Jay Smith | Protein quantitation with cell imaging densitometry |
US6281004B1 (en) * | 1999-04-14 | 2001-08-28 | Cytologix Corporation | Quality control for cytochemical assays |
US7011940B1 (en) | 1999-04-14 | 2006-03-14 | Medical Discovery Partners Llc | Quality control for cytochemical assays |
WO2004046685A2 (en) * | 2002-07-15 | 2004-06-03 | Technical Instrument San Francisco | Quality control of assays |
DE10239739B4 (de) * | 2002-08-29 | 2006-05-11 | Leica Mikrosysteme Gmbh | Vorrichtung und Verfahren zur Durchführung von immunologischen Markierungstechniken für Gewebedünnschnitte |
ES2401865T3 (es) * | 2002-09-26 | 2013-04-25 | Biopath Automation, L.L.C. | Aparato y procedimientos para la manipulación automatizada e incorporación de muestras de tejido |
US7179424B2 (en) | 2002-09-26 | 2007-02-20 | Biopath Automation, L.L.C. | Cassette for handling and holding tissue samples during processing, embedding and microtome procedures, and methods therefor |
WO2004028693A1 (en) * | 2002-09-26 | 2004-04-08 | Biopath Automation, L.L.C. | Cassette and embedding assembly, staging devices, and methods for handling tissue samples |
EP1597578B1 (en) * | 2003-02-27 | 2006-12-20 | Dako Denmark A/S | Standard for immunohistochemistry, immunocytochemistry and molecular cytogenetics. |
DE10309211A1 (de) * | 2003-02-28 | 2004-09-09 | Leica Mikrosysteme Gmbh | Vorrichtung und Verfahren zur immunologischen Markierung für Gewebedünnschnitte |
DE10309210B4 (de) * | 2003-02-28 | 2006-04-27 | Leica Mikrosysteme Gmbh | Verwendung eines Transportbehälters für Objektträger zur immunologischen Markierung für Gewebedünnschnitte |
KR200327028Y1 (ko) * | 2003-06-17 | 2003-09-19 | 장시창 | 인체조직검사기구 |
GB0315991D0 (en) * | 2003-07-08 | 2003-08-13 | Dakocytomation Denmark As | Standard |
AU2004284461A1 (en) * | 2003-10-23 | 2005-05-06 | Georgetown University | Method for two- and three-dimensional microassembly of patterns and structures |
US7582474B2 (en) * | 2005-07-11 | 2009-09-01 | Honeywell International Inc. | Process reactor with layered packed bed |
US20070116612A1 (en) * | 2005-11-02 | 2007-05-24 | Biopath Automation, L.L.C. | Prefix tissue cassette |
US20070141723A1 (en) * | 2005-12-16 | 2007-06-21 | Sompuram Seshi A | Immunohistochemistry staining controls |
US7595874B1 (en) | 2006-02-08 | 2009-09-29 | Sciperio, Inc. | Method of condensed cell slide preparation and detection of rarely occurring cells on microscope slides |
US8131476B2 (en) | 2006-08-07 | 2012-03-06 | General Electric Company | System and method for co-registering multi-channel images of a tissue micro array |
US8060348B2 (en) | 2006-08-07 | 2011-11-15 | General Electric Company | Systems for analyzing tissue samples |
ES2788002T3 (es) * | 2006-12-12 | 2020-10-20 | Biopath Automation Llc | Soporte de biopsia con material celular resiliente seccionable |
EP2313754B1 (en) | 2008-07-18 | 2017-11-01 | Leica Biosystems Newcastle Limited | Method for preparing cell standard |
CA2748542A1 (en) * | 2008-12-30 | 2010-07-08 | Biopath Automation, L.L.C. | Systems and methods for processing tissue samples for histopathology |
AU2010206709B2 (en) * | 2009-01-22 | 2013-01-24 | Biopath Automation, L.L.C. | Microtome sectionable biopsy support for orienting tissue samples |
US10371610B2 (en) | 2016-02-23 | 2019-08-06 | Noul Co., Ltd. | Contact-type patch, staining method using the same, and manufacturing method thereof |
KR20170099739A (ko) | 2016-02-23 | 2017-09-01 | 노을 주식회사 | 접촉식 염색 보조 패치, 그 제조 방법 및 이를 이용하는 염색 방법 |
ES2920502T3 (es) * | 2017-12-06 | 2022-08-04 | Genentech Inc | Controles sintéticos para inmunohistoquímica |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3678151A (en) * | 1969-07-25 | 1972-07-18 | Gugol Clini Tex Inc | Biological staining method |
US3932229A (en) * | 1974-11-15 | 1976-01-13 | Millipore Corporation | Method of sample application to gel electrophoresis media |
SE7609263L (sv) * | 1976-08-20 | 1978-02-21 | Wadsworth Charlies | Forfaringssett for faststellande av kvantiteten av viss i en biologisk vetska loslig komponent, samt apparat for utovande av forfarandet |
US4305721A (en) * | 1979-08-20 | 1981-12-15 | Becton Dickinson & Company | Agglutination assay |
ATE19155T1 (de) * | 1981-10-20 | 1986-04-15 | Shandon Southern Prod | Geraet zur behandlung von gewebe. |
US4603105A (en) * | 1982-05-27 | 1986-07-29 | Kaplan Donald A | Efficient screening methods for low probability variants |
US4695548A (en) * | 1982-11-18 | 1987-09-22 | The Trustees Of Columbia University In The City Of New York | Gel inserts useful in electrophoresis |
EP0117262B1 (de) * | 1983-02-25 | 1988-04-20 | Winfried Dr. med. Stöcker | Verfahren und Vorrichtungen für Untersuchungen an unbeweglich gemachtem biologischem Material |
US4820504A (en) * | 1986-02-12 | 1989-04-11 | City Of Hope | Multi-specimen tissue blocks and slides |
US4816410A (en) * | 1986-10-29 | 1989-03-28 | Coulter Corporation | Control slide for immunoassay kit and method of making same |
US4914022A (en) * | 1987-10-21 | 1990-04-03 | Amc Cancer Research Center | Method for preparing multiple tissue samples for microscopic investigation and testing |
-
1988
- 1988-06-09 GB GB888813628A patent/GB8813628D0/en active Pending
-
1989
- 1989-05-15 ES ES89304886T patent/ES2056216T3/es not_active Expired - Lifetime
- 1989-05-15 EP EP89304886A patent/EP0345953B1/en not_active Expired - Lifetime
- 1989-05-15 AT AT89304886T patent/ATE108554T1/de not_active IP Right Cessation
- 1989-05-15 DE DE68916710T patent/DE68916710T2/de not_active Expired - Fee Related
- 1989-05-31 US US07/359,381 patent/US5143714A/en not_active Expired - Fee Related
- 1989-06-08 JP JP1146526A patent/JPH0232260A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
DE68916710D1 (de) | 1994-08-18 |
ATE108554T1 (de) | 1994-07-15 |
EP0345953A3 (en) | 1991-01-16 |
GB8813628D0 (en) | 1988-07-13 |
DE68916710T2 (de) | 1994-11-03 |
EP0345953A2 (en) | 1989-12-13 |
US5143714A (en) | 1992-09-01 |
JPH0232260A (ja) | 1990-02-02 |
EP0345953B1 (en) | 1994-07-13 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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