ES2056216T3 - Referencia para tecnicas de inmunocoloracion. - Google Patents

Referencia para tecnicas de inmunocoloracion.

Info

Publication number
ES2056216T3
ES2056216T3 ES89304886T ES89304886T ES2056216T3 ES 2056216 T3 ES2056216 T3 ES 2056216T3 ES 89304886 T ES89304886 T ES 89304886T ES 89304886 T ES89304886 T ES 89304886T ES 2056216 T3 ES2056216 T3 ES 2056216T3
Authority
ES
Spain
Prior art keywords
gel
block
pellets
sample
sections
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES89304886T
Other languages
English (en)
Inventor
Raymond Francis Cosgrove
Terence Paul Male
Graeme Mark Smalley
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shandon Diagnostics Ltd
Original Assignee
Life Sciences International Europe Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Life Sciences International Europe Ltd filed Critical Life Sciences International Europe Ltd
Application granted granted Critical
Publication of ES2056216T3 publication Critical patent/ES2056216T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/5436—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals with ligand physically entrapped within the solid phase
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/36—Embedding or analogous mounting of samples
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
    • G01N2001/305—Fixative compositions
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2474/00—Immunochemical assays or immunoassays characterised by detection mode or means of detection
    • G01N2474/20—Immunohistochemistry assay
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/967—Standards, controls, materials, e.g. validation studies, buffer systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

SE PROPORCIONA UN PROCEDIMIENTO Y MATERIAL PARA ENSAYO/CONTROL PARA FACILITAR LA NORMALIZACION DE TECNICAS DE INMUNOTINCION Y LA VALORACION DE SUS RESULTADOS. SE HACE QUE BOLITAS DE UN GEL ADSORBENTE, TAL COMO GEL DE AGAR ADSORBAN CONCENTRACIONES ESPECIFICAS INDIVIDUALES DE UN ANTIGENO DE INTERES. LOS ANTIGENOS ADSORBIDOS ESTAN ENCERRADOS EN LAS BOLITAS INDIVIDUALES COMO POR FIJACION O POR ENCIERRO EN UNA BARRERA DE DIFUSION-INHIBICION, Y LAS BOLITAS SE INSTALAN EN HUECOS INDIVIDUALES EN UN BLOQUE DEL GEL, DE MANERA QUE SE INTEGRAN EN EL. EL BLOQUE SE PUEDE SOMETER LUEGO A LAS MISMAS RUTINAS PREPARATIVAS COMO UNA MUESTRA DE TEJIDO, SECCIONAR Y MONTAR IGUAL QUE LA MUESTRA Y LUEGO SOMETER A INMUNOTINCION MEDIANTE LA MISMA RUTINA QUE LAS SECCIONES DE LA MUESTRA, PARA PROPORCIONAR UNA BASE VALIDA PARA VALORACION DE LAS SECCIONES DE LA MUESTRA TE/IDA POR COMPARACION CON LAS SECCIONES DEL BLOUQE DE GEL TE/IDO. TAMBIEN SE DESCRIBE UN BLOQUE DE GEL DE CONFIGURACION ADECUADA.
ES89304886T 1988-06-09 1989-05-15 Referencia para tecnicas de inmunocoloracion. Expired - Lifetime ES2056216T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB888813628A GB8813628D0 (en) 1988-06-09 1988-06-09 Immunostaining

Publications (1)

Publication Number Publication Date
ES2056216T3 true ES2056216T3 (es) 1994-10-01

Family

ID=10638332

Family Applications (1)

Application Number Title Priority Date Filing Date
ES89304886T Expired - Lifetime ES2056216T3 (es) 1988-06-09 1989-05-15 Referencia para tecnicas de inmunocoloracion.

Country Status (7)

Country Link
US (1) US5143714A (es)
EP (1) EP0345953B1 (es)
JP (1) JPH0232260A (es)
AT (1) ATE108554T1 (es)
DE (1) DE68916710T2 (es)
ES (1) ES2056216T3 (es)
GB (1) GB8813628D0 (es)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
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US5610022A (en) * 1989-09-26 1997-03-11 City Of Hope Internal control for immunocytochemistry assay
US5290706A (en) * 1992-11-10 1994-03-01 Camiener Gerald W Visualization system for retrieval, identification, and positioning of biological samples for subsequent microscopic examination
US5965454A (en) * 1993-02-03 1999-10-12 Histaggen Incorporated Automated histo-cytochemistry apparatus and encapsulation system for processing biological materials
ES2119166T3 (es) * 1993-02-03 1998-10-01 Histaggen Inc Sistema de encapsulacion y aparato de histocitoquimica automatica destinados al tratamiento de sustancias biologicas.
AU748061B2 (en) * 1994-10-18 2002-05-30 Regents Of The University Of California, The The combinatorial synthesis of novel materials
US6699710B1 (en) * 1998-02-25 2004-03-02 The United States Of America As Represented By The Department Of Health And Human Services Tumor tissue microarrays for rapid molecular profiling
US20070166834A1 (en) * 1998-10-05 2007-07-19 Biopath Automation, L.L.C. Apparatus and method for harvesting and handling tissue samples for biopsy analysis
CA2347002A1 (en) 1998-10-21 2000-04-27 Steven Jay Smith Protein quantitation with cell imaging densitometry
US6281004B1 (en) * 1999-04-14 2001-08-28 Cytologix Corporation Quality control for cytochemical assays
US7011940B1 (en) 1999-04-14 2006-03-14 Medical Discovery Partners Llc Quality control for cytochemical assays
WO2004046685A2 (en) * 2002-07-15 2004-06-03 Technical Instrument San Francisco Quality control of assays
DE10239739B4 (de) * 2002-08-29 2006-05-11 Leica Mikrosysteme Gmbh Vorrichtung und Verfahren zur Durchführung von immunologischen Markierungstechniken für Gewebedünnschnitte
ES2401865T3 (es) * 2002-09-26 2013-04-25 Biopath Automation, L.L.C. Aparato y procedimientos para la manipulación automatizada e incorporación de muestras de tejido
US7179424B2 (en) 2002-09-26 2007-02-20 Biopath Automation, L.L.C. Cassette for handling and holding tissue samples during processing, embedding and microtome procedures, and methods therefor
WO2004028693A1 (en) * 2002-09-26 2004-04-08 Biopath Automation, L.L.C. Cassette and embedding assembly, staging devices, and methods for handling tissue samples
EP1597578B1 (en) * 2003-02-27 2006-12-20 Dako Denmark A/S Standard for immunohistochemistry, immunocytochemistry and molecular cytogenetics.
DE10309211A1 (de) * 2003-02-28 2004-09-09 Leica Mikrosysteme Gmbh Vorrichtung und Verfahren zur immunologischen Markierung für Gewebedünnschnitte
DE10309210B4 (de) * 2003-02-28 2006-04-27 Leica Mikrosysteme Gmbh Verwendung eines Transportbehälters für Objektträger zur immunologischen Markierung für Gewebedünnschnitte
KR200327028Y1 (ko) * 2003-06-17 2003-09-19 장시창 인체조직검사기구
GB0315991D0 (en) * 2003-07-08 2003-08-13 Dakocytomation Denmark As Standard
AU2004284461A1 (en) * 2003-10-23 2005-05-06 Georgetown University Method for two- and three-dimensional microassembly of patterns and structures
US7582474B2 (en) * 2005-07-11 2009-09-01 Honeywell International Inc. Process reactor with layered packed bed
US20070116612A1 (en) * 2005-11-02 2007-05-24 Biopath Automation, L.L.C. Prefix tissue cassette
US20070141723A1 (en) * 2005-12-16 2007-06-21 Sompuram Seshi A Immunohistochemistry staining controls
US7595874B1 (en) 2006-02-08 2009-09-29 Sciperio, Inc. Method of condensed cell slide preparation and detection of rarely occurring cells on microscope slides
US8131476B2 (en) 2006-08-07 2012-03-06 General Electric Company System and method for co-registering multi-channel images of a tissue micro array
US8060348B2 (en) 2006-08-07 2011-11-15 General Electric Company Systems for analyzing tissue samples
ES2788002T3 (es) * 2006-12-12 2020-10-20 Biopath Automation Llc Soporte de biopsia con material celular resiliente seccionable
EP2313754B1 (en) 2008-07-18 2017-11-01 Leica Biosystems Newcastle Limited Method for preparing cell standard
CA2748542A1 (en) * 2008-12-30 2010-07-08 Biopath Automation, L.L.C. Systems and methods for processing tissue samples for histopathology
AU2010206709B2 (en) * 2009-01-22 2013-01-24 Biopath Automation, L.L.C. Microtome sectionable biopsy support for orienting tissue samples
US10371610B2 (en) 2016-02-23 2019-08-06 Noul Co., Ltd. Contact-type patch, staining method using the same, and manufacturing method thereof
KR20170099739A (ko) 2016-02-23 2017-09-01 노을 주식회사 접촉식 염색 보조 패치, 그 제조 방법 및 이를 이용하는 염색 방법
ES2920502T3 (es) * 2017-12-06 2022-08-04 Genentech Inc Controles sintéticos para inmunohistoquímica

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3678151A (en) * 1969-07-25 1972-07-18 Gugol Clini Tex Inc Biological staining method
US3932229A (en) * 1974-11-15 1976-01-13 Millipore Corporation Method of sample application to gel electrophoresis media
SE7609263L (sv) * 1976-08-20 1978-02-21 Wadsworth Charlies Forfaringssett for faststellande av kvantiteten av viss i en biologisk vetska loslig komponent, samt apparat for utovande av forfarandet
US4305721A (en) * 1979-08-20 1981-12-15 Becton Dickinson & Company Agglutination assay
ATE19155T1 (de) * 1981-10-20 1986-04-15 Shandon Southern Prod Geraet zur behandlung von gewebe.
US4603105A (en) * 1982-05-27 1986-07-29 Kaplan Donald A Efficient screening methods for low probability variants
US4695548A (en) * 1982-11-18 1987-09-22 The Trustees Of Columbia University In The City Of New York Gel inserts useful in electrophoresis
EP0117262B1 (de) * 1983-02-25 1988-04-20 Winfried Dr. med. Stöcker Verfahren und Vorrichtungen für Untersuchungen an unbeweglich gemachtem biologischem Material
US4820504A (en) * 1986-02-12 1989-04-11 City Of Hope Multi-specimen tissue blocks and slides
US4816410A (en) * 1986-10-29 1989-03-28 Coulter Corporation Control slide for immunoassay kit and method of making same
US4914022A (en) * 1987-10-21 1990-04-03 Amc Cancer Research Center Method for preparing multiple tissue samples for microscopic investigation and testing

Also Published As

Publication number Publication date
DE68916710D1 (de) 1994-08-18
ATE108554T1 (de) 1994-07-15
EP0345953A3 (en) 1991-01-16
GB8813628D0 (en) 1988-07-13
DE68916710T2 (de) 1994-11-03
EP0345953A2 (en) 1989-12-13
US5143714A (en) 1992-09-01
JPH0232260A (ja) 1990-02-02
EP0345953B1 (en) 1994-07-13

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