ES2055962T3 - Preparado farmaceutico de liberacion controlada. - Google Patents
Preparado farmaceutico de liberacion controlada.Info
- Publication number
- ES2055962T3 ES2055962T3 ES91305834T ES91305834T ES2055962T3 ES 2055962 T3 ES2055962 T3 ES 2055962T3 ES 91305834 T ES91305834 T ES 91305834T ES 91305834 T ES91305834 T ES 91305834T ES 2055962 T3 ES2055962 T3 ES 2055962T3
- Authority
- ES
- Spain
- Prior art keywords
- controlled release
- pharmaceutical preparation
- water
- medicinal compound
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
- A61K9/2846—Poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
- A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
Abstract
SE PRESENTA UNA PREPARACION FARMACEUTICA DE LIBERACION CONTROLADA QUE COMPRENDE UN NUCLEO QUE CONTIENE UN COMPUESTO MEDICINAL Y UNA CAPA DE RECUBRIMIENTO QUE CONTIENE UNA SAL REPELENTE DEL AGUA Y UN POLIMERO ACRILICO INSOLUBLE EN AGUA Y LIGERAMENTE PERMEABLE A LA MISMA QUE TIENE UN GRUPO TRIMETIL AMONIOMETIL. DICHA PREPARACION LIBERA UN COMPUESTO MEDICINAL EN UNA FORMA DE DISOLUCION DE TIPO SIGMOIDE CON INDEPENDENCIA DEL PH DEL MEDIO DE DISOLUCION.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP17176290 | 1990-06-28 | ||
SG4995A SG4995G (en) | 1990-06-28 | 1995-01-13 | Controlled release pharmaceutical preparation |
Publications (2)
Publication Number | Publication Date |
---|---|
ES2055962T3 true ES2055962T3 (es) | 1994-09-01 |
ES2055962T5 ES2055962T5 (es) | 1997-09-16 |
Family
ID=26494375
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES91305834T Expired - Lifetime ES2055962T5 (es) | 1990-06-28 | 1991-06-27 | Preparado farmaceutico de liberacion controlada. |
Country Status (17)
Country | Link |
---|---|
US (1) | US5137733A (es) |
EP (1) | EP0463877B2 (es) |
JP (1) | JP2558396B2 (es) |
KR (1) | KR0133511B1 (es) |
CN (1) | CN1040061C (es) |
AT (1) | ATE106241T1 (es) |
CA (1) | CA2045358C (es) |
DE (1) | DE69102211T3 (es) |
DK (1) | DK0463877T3 (es) |
ES (1) | ES2055962T5 (es) |
FI (1) | FI103476B (es) |
GR (1) | GR3024471T3 (es) |
HK (1) | HK33895A (es) |
HU (1) | HU214590B (es) |
IE (1) | IE64629B1 (es) |
IL (1) | IL98611A (es) |
SG (1) | SG4995G (es) |
Families Citing this family (70)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5286493A (en) * | 1992-01-27 | 1994-02-15 | Euroceltique, S.A. | Stabilized controlled release formulations having acrylic polymer coating |
US5681585A (en) | 1991-12-24 | 1997-10-28 | Euro-Celtique, S.A. | Stabilized controlled release substrate having a coating derived from an aqueous dispersion of hydrophobic polymer |
US5580578A (en) * | 1992-01-27 | 1996-12-03 | Euro-Celtique, S.A. | Controlled release formulations coated with aqueous dispersions of acrylic polymers |
US5472712A (en) * | 1991-12-24 | 1995-12-05 | Euroceltique, S.A. | Controlled-release formulations coated with aqueous dispersions of ethylcellulose |
US7070806B2 (en) | 1992-01-27 | 2006-07-04 | Purdue Pharma Lp | Controlled release formulations coated with aqueous dispersions of acrylic polymers |
CN1053808C (zh) * | 1993-04-24 | 2000-06-28 | 章修纲 | 尼非地平控释剂型 |
JP2916978B2 (ja) * | 1993-08-25 | 1999-07-05 | エスエス製薬株式会社 | 放出開始制御型製剤 |
US5834024A (en) * | 1995-01-05 | 1998-11-10 | Fh Faulding & Co. Limited | Controlled absorption diltiazem pharmaceutical formulation |
US5567441A (en) * | 1995-03-24 | 1996-10-22 | Andrx Pharmaceuticals Inc. | Diltiazem controlled release formulation |
US5837284A (en) * | 1995-12-04 | 1998-11-17 | Mehta; Atul M. | Delivery of multiple doses of medications |
US5922736A (en) * | 1995-12-04 | 1999-07-13 | Celegene Corporation | Chronic, bolus administration of D-threo methylphenidate |
US6486177B2 (en) * | 1995-12-04 | 2002-11-26 | Celgene Corporation | Methods for treatment of cognitive and menopausal disorders with D-threo methylphenidate |
US8071128B2 (en) | 1996-06-14 | 2011-12-06 | Kyowa Hakko Kirin Co., Ltd. | Intrabuccally rapidly disintegrating tablet and a production method of the tablets |
US5830503A (en) * | 1996-06-21 | 1998-11-03 | Andrx Pharmaceuticals, Inc. | Enteric coated diltiazem once-a-day formulation |
US6962997B1 (en) * | 1997-05-22 | 2005-11-08 | Celgene Corporation | Process and intermediates for resolving piperidyl acetamide steroisomers |
WO1999001111A1 (en) | 1997-07-02 | 1999-01-14 | Euro-Celtique, S.A. | Stabilized sustained release tramadol formulations |
EP1053752A1 (en) | 1998-02-10 | 2000-11-22 | Yoshitomi Pharmaceutical Industries, Ltd. | Preparations with controlled release |
FR2778848B1 (fr) * | 1998-05-20 | 2001-11-23 | Prographarm Lab | Forme pharmaceutique multiparticulaire a liberation programmee et pulsee et son procede de preparation |
US6524620B2 (en) | 1998-07-20 | 2003-02-25 | Andrx Pharmaceuticals, Inc. | Diltiazem controlled release formulation and method of manufacture |
DE19845358A1 (de) * | 1998-10-02 | 2000-04-06 | Roehm Gmbh | Überzogene Arzneiformen mit kontrollierter Wirkstoffabgabe |
US6322819B1 (en) * | 1998-10-21 | 2001-11-27 | Shire Laboratories, Inc. | Oral pulsed dose drug delivery system |
US6270805B1 (en) | 1998-11-06 | 2001-08-07 | Andrx Pharmaceuticals, Inc. | Two pellet controlled release formulation for water soluble drugs which contains an alkaline metal stearate |
US6039979A (en) * | 1999-01-13 | 2000-03-21 | Laboratoires Prographarm | Multiparticulate pharmaceutical form with programmed and pulsed release and process for its preparation |
DE60028730T2 (de) * | 1999-01-21 | 2006-12-28 | Athpharma Ltd. | Multipartikuläre bisoprolol formulierung |
US6733789B1 (en) | 1999-01-21 | 2004-05-11 | Biovail Laboratories, Inc. | Multiparticulate bisoprolol formulation |
KR100523127B1 (ko) * | 1999-12-23 | 2005-10-20 | 화이자 프로덕츠 인코포레이티드 | 하이드로겔계 약물 투여 형태 |
HUP0204372A3 (en) | 1999-12-23 | 2004-06-28 | Pfizer Prod Inc | Pharmaceutical compositions providing enhanced drug concentrations |
US20040185099A1 (en) * | 2000-01-20 | 2004-09-23 | Biovail Laboratories, Inc. | Multiparticulate bisoprolol formulation |
US6635277B2 (en) | 2000-04-12 | 2003-10-21 | Wockhardt Limited | Composition for pulsatile delivery of diltiazem and process of manufacture |
US6984402B2 (en) | 2000-10-03 | 2006-01-10 | Elite Laboratories, Inc. | Chrono delivery formulations and method of treating atrial fibrillation |
US6620439B1 (en) * | 2000-10-03 | 2003-09-16 | Atul M. Mehta | Chrono delivery formulations and method of use thereof |
SE0100200D0 (sv) | 2001-01-24 | 2001-01-24 | Astrazeneca Ab | New film coating |
AU2002339378A1 (en) * | 2001-05-22 | 2002-12-03 | Euro-Celtique | Compartmentalized dosage form |
US9358214B2 (en) | 2001-10-04 | 2016-06-07 | Adare Pharmaceuticals, Inc. | Timed, sustained release systems for propranolol |
US20030091633A1 (en) * | 2001-11-15 | 2003-05-15 | John Kelly | Methods and compositions for use of (S)-bisoprolol |
US20030118652A1 (en) * | 2001-11-15 | 2003-06-26 | John Kelly | Methods and compositions for use of (S)-bisoprolol |
US20050025824A1 (en) * | 2001-12-14 | 2005-02-03 | Eurand Pharmaceuticals Ltd. | Pulsatile release histamine H2 antagonist dosage form |
US6663888B2 (en) | 2001-12-14 | 2003-12-16 | Eurand Pharmaceuticals Ltd. | Pulsatile release histamine H2 antagonist dosage form |
US8367111B2 (en) * | 2002-12-31 | 2013-02-05 | Aptalis Pharmatech, Inc. | Extended release dosage forms of propranolol hydrochloride |
US7365059B2 (en) * | 2003-03-11 | 2008-04-29 | Seikagaku Corporation | Photocrosslinked-polysaccharide composition and production process of the same |
MXPA05011446A (es) | 2003-04-24 | 2006-05-31 | Jagotec Ag | Tableta con liberacion retardada con geometria de nucleo definida. |
FR2861990B1 (fr) * | 2003-11-10 | 2006-02-10 | Nouveaux Produits Pharma | Comprimes faiblement doses a reseau de polymeres |
US20050239830A1 (en) * | 2004-04-26 | 2005-10-27 | Vikram Khetani | Methods of diminishing co-abuse potential |
WO2005107827A1 (ja) * | 2004-05-07 | 2005-11-17 | Seikagaku Corporation | 髄核充填剤 |
DE102004043863A1 (de) | 2004-09-10 | 2006-03-16 | Nitec Pharma Ag | Tabletten mit orts- und zeitgesteuerter Wirkstofffreisetzung im Gastrointestinum |
US8747895B2 (en) | 2004-09-13 | 2014-06-10 | Aptalis Pharmatech, Inc. | Orally disintegrating tablets of atomoxetine |
US9884014B2 (en) | 2004-10-12 | 2018-02-06 | Adare Pharmaceuticals, Inc. | Taste-masked pharmaceutical compositions |
NZ589750A (en) | 2004-10-21 | 2012-07-27 | Aptalis Pharmatech Inc | Taste-masked pharmaceutical compositions with gastrosoluble pore-formers |
BRPI0517166A (pt) * | 2004-12-09 | 2008-09-30 | Celgene Corp | uso de d-treo-metilfenidato ou um sal do mesmo |
US9161918B2 (en) | 2005-05-02 | 2015-10-20 | Adare Pharmaceuticals, Inc. | Timed, pulsatile release systems |
US8846100B2 (en) * | 2006-05-12 | 2014-09-30 | Shire Llc | Controlled dose drug delivery system |
EA015304B1 (ru) | 2006-08-03 | 2011-06-30 | Нитек Фарма Аг | Лечение ревматоидного заболевания глюкокортикоидами с отсроченным высвобождением |
JP2008024708A (ja) * | 2007-08-20 | 2008-02-07 | Euro-Celtique Sa | アクリル系ポリマーの水性分散液で被膜した放出制御型製剤及びその方法 |
BRPI0921313A2 (pt) * | 2008-11-18 | 2015-12-29 | Ucb Pharma Sa | composição farmaucêutica |
JP2010254691A (ja) * | 2009-04-22 | 2010-11-11 | Dr Suwelack Skin & Health Care Ag | コーティングされた凍結乾燥成型品 |
AU2010325746B2 (en) | 2009-12-02 | 2016-02-25 | Adare Pharmaceuticals S.R.L. | Fexofenadine microcapsules and compositions containing them |
WO2012074042A1 (ja) * | 2010-12-03 | 2012-06-07 | 日本曹達株式会社 | ヒドロキシアルキルセルロース |
US9498447B2 (en) | 2011-03-23 | 2016-11-22 | Ironshore Pharmaceuticals & Development, Inc. | Compositions for treatment of attention deficit hyperactivity disorder |
US9603809B2 (en) | 2011-03-23 | 2017-03-28 | Ironshore Pharmaceuticals & Development, Inc. | Methods of treatment of attention deficit hyperactivity disorder |
US8927010B2 (en) | 2011-03-23 | 2015-01-06 | Ironshore Pharmaceuticals & Development, Inc. | Compositions for treatment of attention deficit hyperactivity disorder |
US10905652B2 (en) | 2011-03-23 | 2021-02-02 | Ironshore Pharmaceuticals & Development, Inc. | Compositions for treatment of attention deficit hyperactivity disorder |
US10292937B2 (en) | 2011-03-23 | 2019-05-21 | Ironshore Pharmaceuticals & Development, Inc. | Methods of treatment of attention deficit hyperactivity disorder |
EP3272342B1 (en) | 2011-03-23 | 2021-05-26 | Ironshore Pharmaceuticals & Development, Inc. | Methods and compositions for treatment of attention deficit disorder |
US9283214B2 (en) | 2011-03-23 | 2016-03-15 | Ironshore Pharmaceuticals & Development, Inc. | Compositions for treatment of attention deficit hyperactivity disorder |
US11241391B2 (en) | 2011-03-23 | 2022-02-08 | Ironshore Pharmaceuticals & Development, Inc. | Compositions for treatment of attention deficit hyperactivity disorder |
US9119809B2 (en) | 2011-03-23 | 2015-09-01 | Ironshore Pharmaceuticals & Development, Inc. | Compositions for treatment of attention deficit hyperactivity disorder |
US8916588B2 (en) | 2011-03-23 | 2014-12-23 | Ironshore Pharmaceuticals & Development, Inc. | Methods for treatment of attention deficit hyperactivity disorder |
JP5146859B2 (ja) * | 2011-07-11 | 2013-02-20 | ユーロ−セルティーク エス.エイ. | アクリル系ポリマーの水性分散液で被膜した放出制御型製剤及びその方法 |
CA2936746C (en) | 2014-10-31 | 2017-06-27 | Purdue Pharma | Methods and compositions particularly for treatment of attention deficit disorder |
US10722473B2 (en) | 2018-11-19 | 2020-07-28 | Purdue Pharma L.P. | Methods and compositions particularly for treatment of attention deficit disorder |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5944311A (ja) * | 1982-09-07 | 1984-03-12 | Santen Pharmaceut Co Ltd | 徐放性顆粒およびその製造法 |
US5002776A (en) * | 1983-12-22 | 1991-03-26 | Elan Corporation, Plc | Controlled absorption diltiazem formulations |
IE56999B1 (en) * | 1983-12-22 | 1992-03-11 | Elan Corp Plc | Pharmaceutical formulation |
US4559225A (en) * | 1984-02-16 | 1985-12-17 | Fourman Robert G | Sunscreen composition |
JPH0621066B2 (ja) * | 1984-03-14 | 1994-03-23 | 杏林製薬株式会社 | 3―イソブチリル―2―イソプロピルピラゾロ〔1,5―a〕ピリジンの徐放性医薬品組成物 |
GB8518301D0 (en) * | 1985-07-19 | 1985-08-29 | Fujisawa Pharmaceutical Co | Hydrodynamically explosive systems |
GB8707416D0 (en) * | 1987-03-27 | 1987-04-29 | Wellcome Found | Pharmaceutical formulations |
IL88083A (en) * | 1987-11-06 | 1992-11-15 | Tanabe Seiyaku Co | Controlled release pharmaceutical dosage form and its preparation |
ATE79029T1 (de) * | 1989-02-11 | 1992-08-15 | Bayer Ag | Arzneimittel mit kontrollierter wirkstoffabgabe. |
US4983401A (en) * | 1989-05-22 | 1991-01-08 | Kinaform Technology, Inc. | Sustained release pharmaceutical preparations having pH controlled membrane coatings |
US5013557A (en) * | 1989-10-03 | 1991-05-07 | Warner-Lambert Company | Taste masking compositions comprising spray dried microcapsules containing sucralfate and methods for preparing same |
JPH0674206B2 (ja) * | 1989-12-28 | 1994-09-21 | 田辺製薬株式会社 | 放出制御型製剤およびその製法 |
-
1991
- 1991-06-11 JP JP3138998A patent/JP2558396B2/ja not_active Expired - Lifetime
- 1991-06-18 FI FI912952A patent/FI103476B/fi not_active IP Right Cessation
- 1991-06-21 IE IE216691A patent/IE64629B1/en not_active IP Right Cessation
- 1991-06-25 IL IL9861191A patent/IL98611A/en not_active IP Right Cessation
- 1991-06-25 CA CA002045358A patent/CA2045358C/en not_active Expired - Lifetime
- 1991-06-27 DE DE69102211T patent/DE69102211T3/de not_active Expired - Lifetime
- 1991-06-27 HU HU912170A patent/HU214590B/hu unknown
- 1991-06-27 AT AT91305834T patent/ATE106241T1/de not_active IP Right Cessation
- 1991-06-27 ES ES91305834T patent/ES2055962T5/es not_active Expired - Lifetime
- 1991-06-27 DK DK91305834.3T patent/DK0463877T3/da active
- 1991-06-27 EP EP91305834A patent/EP0463877B2/en not_active Expired - Lifetime
- 1991-06-28 KR KR1019910010955A patent/KR0133511B1/ko not_active IP Right Cessation
- 1991-06-28 US US07/723,031 patent/US5137733A/en not_active Expired - Lifetime
- 1991-06-28 CN CN91105399A patent/CN1040061C/zh not_active Expired - Lifetime
-
1995
- 1995-01-13 SG SG4995A patent/SG4995G/en unknown
- 1995-03-09 HK HK33895A patent/HK33895A/xx not_active IP Right Cessation
-
1997
- 1997-08-14 GR GR970402109T patent/GR3024471T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
DE69102211D1 (de) | 1994-07-07 |
HK33895A (en) | 1995-03-17 |
HU214590B (hu) | 1998-04-28 |
AU634400B2 (en) | 1993-02-18 |
CA2045358C (en) | 1998-04-28 |
JPH04235123A (ja) | 1992-08-24 |
CA2045358A1 (en) | 1991-12-29 |
CN1058533A (zh) | 1992-02-12 |
ES2055962T5 (es) | 1997-09-16 |
EP0463877B1 (en) | 1994-06-01 |
AU7924391A (en) | 1992-01-02 |
HUT59321A (en) | 1992-05-28 |
IL98611A0 (en) | 1992-07-15 |
DK0463877T3 (da) | 1994-06-27 |
EP0463877B2 (en) | 1997-07-02 |
FI103476B1 (fi) | 1999-07-15 |
DE69102211T3 (de) | 1997-08-28 |
IE912166A1 (en) | 1992-01-01 |
KR0133511B1 (ko) | 1998-04-23 |
CN1040061C (zh) | 1998-10-07 |
FI103476B (fi) | 1999-07-15 |
FI912952A (fi) | 1991-12-29 |
IE64629B1 (en) | 1995-08-23 |
DE69102211T2 (de) | 1994-09-15 |
US5137733A (en) | 1992-08-11 |
HU912170D0 (en) | 1991-12-30 |
GR3024471T3 (en) | 1997-11-28 |
SG4995G (en) | 1995-06-16 |
KR920000313A (ko) | 1992-01-29 |
FI912952A0 (fi) | 1991-06-18 |
JP2558396B2 (ja) | 1996-11-27 |
EP0463877A1 (en) | 1992-01-02 |
IL98611A (en) | 1998-10-30 |
ATE106241T1 (de) | 1994-06-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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