ES2050621A1 - Un procedimiento mejorado para la preparacion de 6-*-aminopenicilinas. - Google Patents
Un procedimiento mejorado para la preparacion de 6-*-aminopenicilinas.Info
- Publication number
- ES2050621A1 ES2050621A1 ES09202244A ES9202244A ES2050621A1 ES 2050621 A1 ES2050621 A1 ES 2050621A1 ES 09202244 A ES09202244 A ES 09202244A ES 9202244 A ES9202244 A ES 9202244A ES 2050621 A1 ES2050621 A1 ES 2050621A1
- Authority
- ES
- Spain
- Prior art keywords
- alpha
- aminopenicillins
- preparation
- improved procedure
- reacting
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Cephalosporin Compounds (AREA)
Abstract
UN PROCEDIMIENTO MEJORADO PARA LA PREPARACION DE 6-AMINOPENICILINAS, PARTICULARMENTE AMPICILINA O AMOXICILINA, EMPLEANDO DISOLVENTES EXENTOS DE ATOMOS DE HALOGENO, QUE COMPRENDE: (A) HACER REACCIONAR UN VINIL AMINOACIDO N-SUSTITUIDO CON UN AGENTE ACILANTE, EN EL SENO DE UN DISOLVENTE AROMATICO, PREFERIBLEMENTE TOLUENO, CON LO QUE SE OBTIENE UN ANHIDRIDO MIXTO; Y (B) HACER REACCIONAR DICHO ANHIDRIDO MIXTO CON UNA SAL DE ACIDO 6-AMINOPENICILANICO (6-APA) EN UN DISOLVENTE ORGANICO, CON LO QUE SE OBTIENEN 6-AMINOPENICILINAS CON UN RENDIMIENTO SUPERIORAL 85% Y UNA PUREZA SUPERIOR AL 98%.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES9202244A ES2050621B1 (es) | 1992-11-06 | 1992-11-06 | Un procedimiento mejorado para la preparacion de 6-*-aminopenicilinas. |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES9202244A ES2050621B1 (es) | 1992-11-06 | 1992-11-06 | Un procedimiento mejorado para la preparacion de 6-*-aminopenicilinas. |
Publications (2)
Publication Number | Publication Date |
---|---|
ES2050621A1 true ES2050621A1 (es) | 1994-05-16 |
ES2050621B1 ES2050621B1 (es) | 1994-12-16 |
Family
ID=8278702
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES9202244A Expired - Fee Related ES2050621B1 (es) | 1992-11-06 | 1992-11-06 | Un procedimiento mejorado para la preparacion de 6-*-aminopenicilinas. |
Country Status (1)
Country | Link |
---|---|
ES (1) | ES2050621B1 (es) |
Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2120150A1 (en) * | 1970-12-31 | 1972-08-11 | Istituto Biochimico Italiano | Anhydrous ampicillin prepn - without isolation of hydrated ampicillin |
US4128547A (en) * | 1977-09-06 | 1978-12-05 | Gist-Brocades N.V. | 6-(D-α-Amino-p-hydroxyphenylacetamido)-penicillanic acid preparation |
GB1594997A (en) * | 1977-04-04 | 1981-08-05 | Galenika Pharmaceutical | Process for the preparation of amoxicillin |
GB2087871A (en) * | 1980-11-17 | 1982-06-03 | Pliva Pharm & Chem Works | Manufacture of semisynthetic penicillins |
EP0439096A2 (en) * | 1990-01-22 | 1991-07-31 | Biochemie Gesellschaft M.B.H. | Improvements in or relating to beta lactam production |
-
1992
- 1992-11-06 ES ES9202244A patent/ES2050621B1/es not_active Expired - Fee Related
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2120150A1 (en) * | 1970-12-31 | 1972-08-11 | Istituto Biochimico Italiano | Anhydrous ampicillin prepn - without isolation of hydrated ampicillin |
GB1594997A (en) * | 1977-04-04 | 1981-08-05 | Galenika Pharmaceutical | Process for the preparation of amoxicillin |
US4128547A (en) * | 1977-09-06 | 1978-12-05 | Gist-Brocades N.V. | 6-(D-α-Amino-p-hydroxyphenylacetamido)-penicillanic acid preparation |
GB2087871A (en) * | 1980-11-17 | 1982-06-03 | Pliva Pharm & Chem Works | Manufacture of semisynthetic penicillins |
EP0439096A2 (en) * | 1990-01-22 | 1991-07-31 | Biochemie Gesellschaft M.B.H. | Improvements in or relating to beta lactam production |
Also Published As
Publication number | Publication date |
---|---|
ES2050621B1 (es) | 1994-12-16 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
SE9404290L (sv) | Förfarande för framställning av klavulansyra | |
AU6844790A (en) | Novel a-nor-steriod-3-carboxylic acid derivatives | |
EP0279466A3 (en) | Novel naphthalene derivatives and antiallergy and anti-inflammatory pharmaceuticals | |
FI925988A (fi) | Foerfarande foer framstaellning av b-laktamer | |
AU1051192A (en) | Process for the combined production of organic compounds and power | |
AU7836487A (en) | Oligomerization of primary aromatic amines | |
AU6802887A (en) | Production of liquid helium liquid nitrogen from crude helium feed. | |
LV10256B (en) | Novel acylale of imidazole-5-carboxylic acid derivatives, process for producing thereof and using same | |
CA2020838A1 (en) | Hemoregulatory peptides | |
AU2954992A (en) | Process for preparing n-(arylsulphonyl)-carbamide acid derivates and intermediates useful for carrying out this process | |
ES2050621A1 (es) | Un procedimiento mejorado para la preparacion de 6-*-aminopenicilinas. | |
AU6740296A (en) | Process for the preparation of potassium clavulanate | |
NZ322485A (en) | Production of a salt of clavulanic acid using n-butanol or isobutanol as the solvent which contains 0.5-10% of water | |
HU9201412D0 (en) | Process for the enzymatic hydrolysis of carbonic acid derivatives | |
MY114213A (en) | Clavulanic acid salts | |
IL85393A (en) | Foldable boom for air atomization of chemical products on crop fields | |
SI0736009T1 (en) | N-oxides of 4-arylpiperazines and 4-arylpiperidines as antipsychotic drugs | |
AU4610689A (en) | Pyridine-3-peroxycarboxylic acid monopersulfate | |
AU8388891A (en) | Acaricidal agents based on azomethines of 2,3-diaminomaleic acid nitrile | |
JPS6440499A (en) | Folic acid-analog derivative and production thereof | |
AU3863089A (en) | Process for the production of dinitrotoluene or mononitrobenzene | |
CA2153264A1 (en) | New cyclopropyl derivatives, preparation method thereof and applications | |
AU7677798A (en) | Process for the preparation of ampicillin | |
JPS6422862A (en) | Alpha-diazothiazolylacetic acid derivative | |
CA2193932A1 (en) | Process for producing isatoic anhydrides |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD1A | Patent lapsed |
Effective date: 20051107 |