ES2049636A1 - Quinoline carboxylic acid deriv prepn - by reacting boron complex of quinoline deriv with nucleophilic cpd - Google Patents
Quinoline carboxylic acid deriv prepn - by reacting boron complex of quinoline deriv with nucleophilic cpdInfo
- Publication number
- ES2049636A1 ES2049636A1 ES9200816A ES9200816A ES2049636A1 ES 2049636 A1 ES2049636 A1 ES 2049636A1 ES 9200816 A ES9200816 A ES 9200816A ES 9200816 A ES9200816 A ES 9200816A ES 2049636 A1 ES2049636 A1 ES 2049636A1
- Authority
- ES
- Spain
- Prior art keywords
- deriv
- quinoline
- nucleophilic
- carboxylic acid
- boron complex
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Abstract
Procedure for preparing quinoline carboxylic acid derivatives with formula I, (R<5> = nucleophile R = aliphatic or aromatic radical) based on the reaction of a nucleophile with a boron complex with formula II (R<1>, R<2> are halogen, methane sulphonate or trifluoro methane sulphonate R<3> = halogen or nitro R<4> = hydrogen or fluorine).These derivatives have outstanding antibacterial properties.< IMAGE >Quinoline carboxylic acid derivs. of formula (I), in which R5 is a nucleophilic gp. and R is an aliphatic or aromatic radical, are made by reaction of a nucleophilic with a boron complex of formula (II), in which R1 and R2 are halogen, methane sulphonate or trifluoromethane sulphonate, R3 is halogen or nitro and R4 is H or fluorine.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES9200816A ES2049636B1 (en) | 1992-04-15 | 1992-04-15 | PROCEDURE FOR THE PREPARATION OF QUINOLINCARBOXILIC ACID DERIVATIVES. |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES9200816A ES2049636B1 (en) | 1992-04-15 | 1992-04-15 | PROCEDURE FOR THE PREPARATION OF QUINOLINCARBOXILIC ACID DERIVATIVES. |
Publications (2)
Publication Number | Publication Date |
---|---|
ES2049636A1 true ES2049636A1 (en) | 1994-04-16 |
ES2049636B1 ES2049636B1 (en) | 1994-12-16 |
Family
ID=8276755
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES9200816A Expired - Lifetime ES2049636B1 (en) | 1992-04-15 | 1992-04-15 | PROCEDURE FOR THE PREPARATION OF QUINOLINCARBOXILIC ACID DERIVATIVES. |
Country Status (1)
Country | Link |
---|---|
ES (1) | ES2049636B1 (en) |
Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1987003587A1 (en) * | 1985-12-09 | 1987-06-18 | Chinoin Gyógyszer és Vegyészeti Termékek Gyára Rt. | Process for the preparation of quinoline carboxylic acids |
ES2001464A6 (en) * | 1986-12-19 | 1988-05-16 | Chinoin Gyogyszer Es Vegyeszet | Prepn. of oxo-di:hydroxy piperazino:quinoline carboxylic acid cpds. |
WO1988007998A1 (en) * | 1987-04-08 | 1988-10-20 | Chinoin Gyógyszer és Vegyészeti Termékek Gyára Rt. | Quinoline carboxylic acid boric acid anhydrides and process for the preparation thereof |
ES2006882A6 (en) * | 1987-04-08 | 1989-05-16 | Chinoin Gyogyszer Es Vegyeszet | Procedure for the preparation of quinolincarboxilic acids. (Machine-translation by Google Translate, not legally binding) |
ES2006994A6 (en) * | 1987-06-24 | 1989-05-16 | Chinoin Gyogyszer Es Vegyeszet | Process for the preparation of quinoline carboxylic acid derivatives. |
ES2009402A6 (en) * | 1988-11-23 | 1989-09-16 | Salvat | Procedure for obtaining the acid 1-ciclopropil-6-fluoro-7- (piperacinil) -1,4-dihidrido-4-oxo-quinolin-3-carboxilico. (Machine-translation by Google Translate, not legally binding) |
-
1992
- 1992-04-15 ES ES9200816A patent/ES2049636B1/en not_active Expired - Lifetime
Patent Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1987003587A1 (en) * | 1985-12-09 | 1987-06-18 | Chinoin Gyógyszer és Vegyészeti Termékek Gyára Rt. | Process for the preparation of quinoline carboxylic acids |
ES2001464A6 (en) * | 1986-12-19 | 1988-05-16 | Chinoin Gyogyszer Es Vegyeszet | Prepn. of oxo-di:hydroxy piperazino:quinoline carboxylic acid cpds. |
WO1988007998A1 (en) * | 1987-04-08 | 1988-10-20 | Chinoin Gyógyszer és Vegyészeti Termékek Gyára Rt. | Quinoline carboxylic acid boric acid anhydrides and process for the preparation thereof |
ES2006881A6 (en) * | 1987-04-08 | 1989-05-16 | Chinoin Gyogyszer Es Vegyeszet | Quinoline carboxylic acid boric acid anhydrides and process for the preparation thereof. |
ES2006882A6 (en) * | 1987-04-08 | 1989-05-16 | Chinoin Gyogyszer Es Vegyeszet | Procedure for the preparation of quinolincarboxilic acids. (Machine-translation by Google Translate, not legally binding) |
ES2006994A6 (en) * | 1987-06-24 | 1989-05-16 | Chinoin Gyogyszer Es Vegyeszet | Process for the preparation of quinoline carboxylic acid derivatives. |
ES2009402A6 (en) * | 1988-11-23 | 1989-09-16 | Salvat | Procedure for obtaining the acid 1-ciclopropil-6-fluoro-7- (piperacinil) -1,4-dihidrido-4-oxo-quinolin-3-carboxilico. (Machine-translation by Google Translate, not legally binding) |
Also Published As
Publication number | Publication date |
---|---|
ES2049636B1 (en) | 1994-12-16 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FA2A | Application withdrawn |
Effective date: 19950425 |