MD118C2 - Method of obtaining of joint anhydride of quinoline-carboxylic acide and of boric acide - Google Patents
Method of obtaining of joint anhydride of quinoline-carboxylic acide and of boric acideInfo
- Publication number
- MD118C2 MD118C2 MD94-0133A MD940133A MD118C2 MD 118 C2 MD118 C2 MD 118C2 MD 940133 A MD940133 A MD 940133A MD 118 C2 MD118 C2 MD 118C2
- Authority
- MD
- Moldova
- Prior art keywords
- acide
- quinoline
- boric
- anhydride
- joint
- Prior art date
Links
- 150000008064 anhydrides Chemical class 0.000 title 1
- LOAUVZALPPNFOQ-UHFFFAOYSA-N quinaldic acid Chemical compound C1=CC=CC2=NC(C(=O)O)=CC=C21 LOAUVZALPPNFOQ-UHFFFAOYSA-N 0.000 title 1
- PXGOKWXKJXAPGV-UHFFFAOYSA-N Fluorine Chemical compound FF PXGOKWXKJXAPGV-UHFFFAOYSA-N 0.000 abstract 2
- 239000003153 chemical reaction reagent Substances 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 229910052731 fluorine Inorganic materials 0.000 abstract 2
- 239000011737 fluorine Substances 0.000 abstract 2
- 229910052736 halogen Inorganic materials 0.000 abstract 2
- 150000002367 halogens Chemical class 0.000 abstract 2
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 1
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical group [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 abstract 1
- 125000001931 aliphatic group Chemical group 0.000 abstract 1
- 230000000844 anti-bacterial effect Effects 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 125000001559 cyclopropyl group Chemical group [H]C1([H])C([H])([H])C1([H])* 0.000 abstract 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 239000013067 intermediate product Substances 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 239000000047 product Substances 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
- 238000006467 substitution reaction Methods 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
Abstract
Usage as intermediate product for the synthesis of compounds with an antibacterial activity. The summary of the invention: a product with general formula:wherein: R1 and R2 represent halogen or acyloxigroup aliphatic with 2-6 carbon atoms, R3 represents chlor of fluorine, R4 represents cyclopropyl, ethyl or phenyl, with a possible substitution by one or two halogen, R5 represents hydrogen or fluorine.The reagent 1 is a compound with general formula:wherein R3; R4 and R5 have the above indicated meanings.R6 represents C1-C4 alkyl. The reagent r:B (OCOR6)3 in one solvent's medium.
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU871504A HU198728B (en) | 1987-04-08 | 1987-04-08 | Process for the preparation of quinoline carboxylic acid derivatives |
| HU873147A HU200187B (en) | 1987-07-10 | 1987-07-10 | Process for producing (1-substituted-6-fluoro-7-chloro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid-boric) anhydrides |
| PCT/HU1988/000018 WO1988007998A1 (en) | 1987-04-08 | 1988-04-08 | Quinoline carboxylic acid boric acid anhydrides and process for the preparation thereof |
| SU884613042A RU1804457C (en) | 1987-04-08 | 1988-12-07 | Method of quinolinecarboxylic acid and boric acid mixed anhydrides synthesis |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MD118B1 MD118B1 (en) | 1994-12-31 |
| MD118C2 true MD118C2 (en) | 1995-06-30 |
Family
ID=27269961
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MD94-0134A MD71C2 (en) | 1987-04-08 | 1994-04-08 | The mixture of anhydrides of acids chinoline-carboxylic and acid boric as intermidiate products for obtaining |
| MD94-0133A MD118C2 (en) | 1987-04-08 | 1994-04-08 | Method of obtaining of joint anhydride of quinoline-carboxylic acide and of boric acide |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MD94-0134A MD71C2 (en) | 1987-04-08 | 1994-04-08 | The mixture of anhydrides of acids chinoline-carboxylic and acid boric as intermidiate products for obtaining |
Country Status (2)
| Country | Link |
|---|---|
| LV (1) | LV5480A3 (en) |
| MD (2) | MD71C2 (en) |
-
1993
- 1993-06-22 LV LV930655A patent/LV5480A3/en unknown
-
1994
- 1994-04-08 MD MD94-0134A patent/MD71C2/en active IP Right Grant
- 1994-04-08 MD MD94-0133A patent/MD118C2/en active IP Right Grant
Non-Patent Citations (1)
| Title |
|---|
| Brevet nr. 3142854, DE, Int. cl. C 07 D 401/04, 1983 * |
Also Published As
| Publication number | Publication date |
|---|---|
| MD118B1 (en) | 1994-12-31 |
| MD71B1 (en) | 1994-10-31 |
| MD71C2 (en) | 1995-01-31 |
| LV5480A3 (en) | 1994-03-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG4A | Patent for invention issued | ||
| IF99 | Valid patent on 19990615 |
Free format text: EXPIRES: 20080407 |