ES2044834T3 - Procedimiento para la obtencion de tioeteres aromaticos. - Google Patents
Procedimiento para la obtencion de tioeteres aromaticos.Info
- Publication number
- ES2044834T3 ES2044834T3 ES86117740T ES86117740T ES2044834T3 ES 2044834 T3 ES2044834 T3 ES 2044834T3 ES 86117740 T ES86117740 T ES 86117740T ES 86117740 T ES86117740 T ES 86117740T ES 2044834 T3 ES2044834 T3 ES 2044834T3
- Authority
- ES
- Spain
- Prior art keywords
- represents hydrogen
- radical
- alkyl
- single bond
- symbols
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/10—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C323/18—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton
- C07C323/19—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton with singly-bound oxygen atoms bound to acyclic carbon atoms of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
- C07D311/24—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
Abstract
NUEVO TIPO DE TIOETER NO SIMETRICO DE LA FORMULA (I) DONDE LOS SIMBOLOS GENERALES TIENEN LOS SIGUIENTES SIGNIFICADOS: R0 ES HIDROGENO O C1-ALCANOILO; R1 ES C1-C3 ALQUILO, QUE PUEDE SER SUSTITUIDO POR UNO O MAS HALOGENOS CON NUMERO MAXIMO DE 17 ATOMOS, R2 ES UN RESTO ALIFATICO CON 5-15C ATOMOS, A ES ETILENO, EL ENLACE SENCILLO O VINILENO; B1 ES C1-7-ALQUILENO O FENILENO; B2 ES UN ENLACE SENCILLO, ETILENO O FENILENO; Y M ES UN RESTO AROMATICO DE LA FORMULA PARCIAL (M) CON LOS SIGUIENTES SIGNIFICADOS DE LOS SIMBOLOS: R3 ES HIDROGENO O C1-4ALQUILO; X ES NH, O, S O CUANDO R4 ES HIDROGENO, EL ENLACE SIMPLE; UNO DE LOS SIMBOLOS R4 Y R5 SIGNIFICA HIDROGENO, Y EL OTRO EL GRUPO -CO-R6, O R4 Y R5 JUNTOS SIGNIFICAN EL RESTO -CO-C(R6)=C(R7)- O -CO-C(R7) =C(R6)O R4 Y R5 JUNTO CON X SIGNIFICAN EL RESTO -N=C(R8) -C(R6)=CH-; DONDE R6 ES -(CH2)B-COOR3, (DONDE B=0 A 2); R7 ES HIDROGENO O C1-4-ALQUILO Y R8 ES HIDROGENO, METILO, METOXI O HALOGENO Y SUS SALES SON ACTIVAS COMO ANTAGONISTAS DE LEUKOTRIENO Y APROPIADAS PARA TRATAMIENTO DE ESTADOS ALERGICOS Y ASMATICOS.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH551385 | 1985-12-23 | ||
CH132186 | 1986-04-04 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2044834T3 true ES2044834T3 (es) | 1994-01-16 |
Family
ID=25687324
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES86117740T Expired - Lifetime ES2044834T3 (es) | 1985-12-23 | 1986-12-19 | Procedimiento para la obtencion de tioeteres aromaticos. |
Country Status (16)
Country | Link |
---|---|
US (1) | US4785004A (es) |
EP (1) | EP0228045B1 (es) |
KR (1) | KR870005986A (es) |
AT (1) | ATE62223T1 (es) |
AU (1) | AU6681786A (es) |
CA (1) | CA1274522A (es) |
DE (1) | DE3678545D1 (es) |
DK (1) | DK624286A (es) |
ES (1) | ES2044834T3 (es) |
FI (1) | FI865241A (es) |
GR (1) | GR3001727T3 (es) |
HU (1) | HUT46658A (es) |
IL (1) | IL81056A0 (es) |
NO (1) | NO865233L (es) |
NZ (1) | NZ218762A (es) |
PT (1) | PT83992B (es) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5017583A (en) * | 1983-04-21 | 1991-05-21 | Merck Frosst Canada, Inc. | Leukotriene antagonists |
GB8523776D0 (en) * | 1985-09-26 | 1985-10-30 | Scras | Catechol derivatives |
GB8709546D0 (en) * | 1987-04-22 | 1987-05-28 | Lilly Industries Ltd | Pharmaceutical use of organic compounds |
GB8709547D0 (en) * | 1987-04-22 | 1987-05-28 | Lilly Industries Ltd | Organic compounds |
DE3724735A1 (de) * | 1987-07-25 | 1989-02-02 | Hoechst Ag | Leukotrienantagonisten, verfahren zu ihrer herstellung, ihre anwendung zur behandlung von krankheiten, sowie vorprodukte |
DE3724669A1 (de) * | 1987-07-25 | 1989-02-02 | Hoechst Ag | Leukotrienantagonisten, verfahren zu ihrer herstellung und ihre anwendung zur behandlung von krankheiten |
GB8725260D0 (en) * | 1987-10-28 | 1987-12-02 | Lilly Industries Ltd | Organic compounds |
GB8807016D0 (en) * | 1988-03-24 | 1988-04-27 | Lilly Industries Ltd | Organic compounds & their pharmaceutical use |
US5149717A (en) * | 1988-03-29 | 1992-09-22 | Ciba-Geigy Corporation | Alkanophenones useful for treating allergies |
IL89713A0 (en) * | 1988-03-29 | 1989-09-28 | Ciba Geigy Ag | Novel alkanophenones |
IL93765A (en) * | 1989-04-11 | 1995-08-31 | Basf Ag | Oxirane Phenyl Esters and fungicides containing them |
EP0419411A3 (en) * | 1989-09-19 | 1991-09-04 | Ciba-Geigy Ag | Additional alkanophenones |
EP0419410A3 (en) * | 1989-09-19 | 1991-08-14 | Ciba-Geigy Ag | Alkanophenones |
GB9015892D0 (en) * | 1990-07-19 | 1990-09-05 | Tioxide Group Services Ltd | Compositions |
EP3133067A1 (en) | 2015-08-21 | 2017-02-22 | Merck Patent GmbH | Compounds for optically active devices |
EP3133065A1 (en) * | 2015-08-21 | 2017-02-22 | Merck Patent GmbH | Compounds for optically active devices |
EP3133066A1 (en) | 2015-08-21 | 2017-02-22 | Merck Patent GmbH | Hydrophilic compounds for optically active devices |
EP3363786A1 (en) | 2017-02-15 | 2018-08-22 | Merck Patent GmbH | Compounds for optically active devices |
EP3363793A1 (en) | 2017-02-15 | 2018-08-22 | Merck Patent GmbH | Hydrophobic compounds for optically active devices |
US20210355113A1 (en) | 2018-07-23 | 2021-11-18 | Bristol-Myers Squibb Company | Inhibitors of indoleamine 2,3-dioxygenase and methods of their use |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4609744A (en) * | 1983-04-21 | 1986-09-02 | Merck Frosst Canada Inc. | 4-oxo-benzopyran carboxylic acids |
EP0123543B1 (en) * | 1983-04-21 | 1988-02-03 | Merck Frosst Canada Inc. | Leukotriene antagonists, their production and use and compositions containing them |
GB8320943D0 (en) * | 1983-08-03 | 1983-09-07 | Lilly Industries Ltd | Organic compounds |
EP0170048B1 (de) * | 1984-06-28 | 1991-04-17 | Ciba-Geigy Ag | Aliphatische Thioether |
-
1986
- 1986-12-15 US US06/941,676 patent/US4785004A/en not_active Expired - Fee Related
- 1986-12-19 ES ES86117740T patent/ES2044834T3/es not_active Expired - Lifetime
- 1986-12-19 DE DE8686117740T patent/DE3678545D1/de not_active Expired - Lifetime
- 1986-12-19 FI FI865241A patent/FI865241A/fi not_active IP Right Cessation
- 1986-12-19 CA CA000525826A patent/CA1274522A/en not_active Expired - Lifetime
- 1986-12-19 AT AT86117740T patent/ATE62223T1/de not_active IP Right Cessation
- 1986-12-19 EP EP86117740A patent/EP0228045B1/de not_active Expired - Lifetime
- 1986-12-22 PT PT83992A patent/PT83992B/pt not_active IP Right Cessation
- 1986-12-22 NZ NZ218762A patent/NZ218762A/xx unknown
- 1986-12-22 AU AU66817/86A patent/AU6681786A/en not_active Abandoned
- 1986-12-22 HU HU865384A patent/HUT46658A/hu unknown
- 1986-12-22 IL IL81056A patent/IL81056A0/xx unknown
- 1986-12-22 DK DK624286A patent/DK624286A/da not_active Application Discontinuation
- 1986-12-22 NO NO865233A patent/NO865233L/no unknown
- 1986-12-23 KR KR860011119A patent/KR870005986A/ko not_active Application Discontinuation
-
1991
- 1991-04-04 GR GR90401112T patent/GR3001727T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
US4785004A (en) | 1988-11-15 |
HUT46658A (en) | 1988-11-28 |
DE3678545D1 (en) | 1991-05-08 |
FI865241A0 (fi) | 1986-12-19 |
KR870005986A (ko) | 1987-07-08 |
AU6681786A (en) | 1987-06-25 |
NO865233L (no) | 1987-06-24 |
NZ218762A (en) | 1989-01-27 |
PT83992A (de) | 1987-01-01 |
EP0228045A2 (de) | 1987-07-08 |
GR3001727T3 (en) | 1992-11-23 |
NO865233D0 (no) | 1986-12-22 |
FI865241A (fi) | 1987-06-24 |
PT83992B (pt) | 1989-07-31 |
DK624286D0 (da) | 1986-12-22 |
CA1274522A (en) | 1990-09-25 |
IL81056A0 (en) | 1987-03-31 |
DK624286A (da) | 1987-06-24 |
ATE62223T1 (de) | 1991-04-15 |
EP0228045A3 (en) | 1988-09-07 |
EP0228045B1 (de) | 1991-04-03 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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