ES2042395A1 - Cyano piperazinyl quinoxaline deriv. prepn. - Google Patents
Cyano piperazinyl quinoxaline deriv. prepn.Info
- Publication number
- ES2042395A1 ES2042395A1 ES929200430A ES9200430A ES2042395A1 ES 2042395 A1 ES2042395 A1 ES 2042395A1 ES 929200430 A ES929200430 A ES 929200430A ES 9200430 A ES9200430 A ES 9200430A ES 2042395 A1 ES2042395 A1 ES 2042395A1
- Authority
- ES
- Spain
- Prior art keywords
- cyano
- piperazinyl
- prepn
- deriv
- quinoxaline
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Abstract
2-Cyano 3-piperazinyl qunoxalines of formula (I), which are selective antagonists of 5HT3 receptors and useful for treatment of nausea, vomiting, gastric complaints, anxiety states and pyschotic reactions, are made by replacing halogen in 2-cyano 3-halo quinoxalines with a substituted piperazinyl gp.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES9200430A ES2042395B1 (en) | 1992-02-27 | 1992-02-27 | PROCEDURE FOR THE OBTAINING OF DERIVATIVES OF 2-CIANO-3-PIPERACINILQUINOXALINAS. |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES9200430A ES2042395B1 (en) | 1992-02-27 | 1992-02-27 | PROCEDURE FOR THE OBTAINING OF DERIVATIVES OF 2-CIANO-3-PIPERACINILQUINOXALINAS. |
Publications (2)
Publication Number | Publication Date |
---|---|
ES2042395A1 true ES2042395A1 (en) | 1993-12-01 |
ES2042395B1 ES2042395B1 (en) | 1994-06-16 |
Family
ID=8276207
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES9200430A Expired - Fee Related ES2042395B1 (en) | 1992-02-27 | 1992-02-27 | PROCEDURE FOR THE OBTAINING OF DERIVATIVES OF 2-CIANO-3-PIPERACINILQUINOXALINAS. |
Country Status (1)
Country | Link |
---|---|
ES (1) | ES2042395B1 (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2002036113A1 (en) * | 2000-11-01 | 2002-05-10 | Respiratorius Ab | Composition comprising: serotonin receptor antagonists (5ht-2, 5ht-3) and agonist (5ht-4) |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2236499A1 (en) * | 1973-07-13 | 1975-02-07 | Merck & Co Inc |
-
1992
- 1992-02-27 ES ES9200430A patent/ES2042395B1/en not_active Expired - Fee Related
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2236499A1 (en) * | 1973-07-13 | 1975-02-07 | Merck & Co Inc |
Non-Patent Citations (1)
Title |
---|
JOURNAL OF MEDICINAL CHEMISTRY, Vol. 24, 1981, p. 93-101, LUMMA et al., "Piperazinylquinoxalines with Central Serotoninmimetic Activity". * |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2002036113A1 (en) * | 2000-11-01 | 2002-05-10 | Respiratorius Ab | Composition comprising: serotonin receptor antagonists (5ht-2, 5ht-3) and agonist (5ht-4) |
Also Published As
Publication number | Publication date |
---|---|
ES2042395B1 (en) | 1994-06-16 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
PL338352A1 (en) | Derivatives of 1-(n-phenylaminoalkyl)-piperazine substituted at position 2 of its phenyl ring | |
EA199900693A1 (en) | Atropisomers of 3-aryl-4 (3H) -CHINAZOLINONES AND THEIR USE AS ANTAGONISTS OF AMPA RECEPTORS | |
HK1045994A1 (en) | Methods and compositions utilizing quinazolinones | |
PL363907A1 (en) | Fused pyridine derivatives for use as vanilloid receptor antagonists for treating pain. | |
DK1020460T3 (en) | Sodium salt of the (-) enantiomer of omeprazole | |
MXPA02001764A (en) | Heteropolycyclic compounds and their use as metabotropic glutamate receptor antagonists. | |
PL397846A1 (en) | Treatment of disorders associated with TNFα | |
PE20030292A1 (en) | FUSED BICYCLE HETEROARYL COMPOUNDS REPLACED WITH HETEROARYL AS GABAA RECEIVER LINKS | |
DE60034783D1 (en) | SELECTIVE NPY (Y5) ANTAGONISTS | |
DK0901374T3 (en) | Tetrahydropteridines and pyridylpiperazines for the treatment of neurological disorders | |
GB0117277D0 (en) | Therapeutic agents | |
TR200000333T2 (en) | 4-aminopyrol (3,2-d) pyrimidines as Y receptor antagonists. | |
IL153554A (en) | Methods and compositions utilizing quinazolinones | |
WO1997035539A3 (en) | Arylamino fused pyridines and pyrimidines | |
WO2002044142A3 (en) | Piperazine derivatives, their preparation and their use for treating central nervous system (cns) disorders | |
HUP9901473A2 (en) | 2,3-benzodiazepine derivatives, process for producing them and pharmaceutical compositions containing them | |
GB9801208D0 (en) | Therapeutic agents | |
AU8117798A (en) | Fused polycyclic 2-aminopyrimidine derivatives as protein kinase inhibitors | |
ES2042395A1 (en) | Cyano piperazinyl quinoxaline deriv. prepn. | |
ES2120463T3 (en) | (PIRIDINILAMINO) -BENZISOXAZOLES AND -BENZOISOTIAZOLES SUBSTITUTED A PROCEDURE FOR ITS PREPARATION AND USE AS MEDICINES. | |
DK1000046T3 (en) | Piperazine derivatives active on the lower urinary tract | |
FI98704B (en) | Process for producing receptors with binding activity for the small receptor group rhinoviruses and their use | |
HU9203325D0 (en) | Benzo-thieno(2,3-b)pyrazine-2,3(1h,4h)-dione derivatives | |
HUT60716A (en) | New process for producing 3-substituted indole compounds | |
NO20012538L (en) | Use of N-substituted azabicycloalkane derivatives for the treatment of central nervous system disorders |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD1A | Patent lapsed |
Effective date: 20000201 |