ES2042153T3 - Agentes para el tratamiento de estados de dolor graves y procedimientopara su preparacion. - Google Patents

Agentes para el tratamiento de estados de dolor graves y procedimientopara su preparacion.

Info

Publication number
ES2042153T3
ES2042153T3 ES199090114108T ES90114108T ES2042153T3 ES 2042153 T3 ES2042153 T3 ES 2042153T3 ES 199090114108 T ES199090114108 T ES 199090114108T ES 90114108 T ES90114108 T ES 90114108T ES 2042153 T3 ES2042153 T3 ES 2042153T3
Authority
ES
Spain
Prior art keywords
weight
parts
agents
procedure
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES199090114108T
Other languages
English (en)
Inventor
Manfred Lohner
Klaus Dr. Posselt
Ute Dr. Med. Vogtle-Junkert
Hans H. Prof. Dr. Med. Wagener
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Dolorgiet GmbH and Co KG
Original Assignee
Dolorgiet GmbH and Co KG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dolorgiet GmbH and Co KG filed Critical Dolorgiet GmbH and Co KG
Application granted granted Critical
Publication of ES2042153T3 publication Critical patent/ES2042153T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Endoscopes (AREA)
  • Instructional Devices (AREA)
  • Steroid Compounds (AREA)

Abstract

EL INVENTO SE REFIERE A UN MEDIO QUE SE UTILIZA PARA EL TRATAMIENTO DE ESTADOS DE DOLOR AGUDO COMO DOLORES POSOPERATIVOS Y DOLORES TUMULARES Y CONSISTE EN CAPSULAS DE GELATINA BLANDAS QUE CONTIENEN DE 30 A 50 PARTES EN PESO DE IBUPROFEN Y DE 1,5 A 4 PARTES EN PESO DE CODEINA Y SUS SALES TOLERABLES FISIOLOGICAMENTE QUE PARCIALMENTE SE DILUYEN Y SE SUSPENDEN EN 68,5 A 48 PARTES EN PESO DE POLIOXIETILENO UNA MEZCLA DE 30 A 76 PARTES EN PESO DE POLIOXIETILENO XIPROPILENO A 40 PARTES EN PESO DE UNOS TENSIOACTIVOS TOLERABLES FISIOLOGICAMENTE.
ES199090114108T 1989-08-17 1990-07-24 Agentes para el tratamiento de estados de dolor graves y procedimientopara su preparacion. Expired - Lifetime ES2042153T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3927113A DE3927113C2 (de) 1989-08-17 1989-08-17 Mittel zur Behandlung von schweren Schmerzzuständen und Verfahren zu ihrer Herstellung

Publications (1)

Publication Number Publication Date
ES2042153T3 true ES2042153T3 (es) 1993-12-01

Family

ID=6387265

Family Applications (1)

Application Number Title Priority Date Filing Date
ES199090114108T Expired - Lifetime ES2042153T3 (es) 1989-08-17 1990-07-24 Agentes para el tratamiento de estados de dolor graves y procedimientopara su preparacion.

Country Status (12)

Country Link
US (1) US5173304A (es)
EP (1) EP0413171B1 (es)
JP (1) JPH03169809A (es)
AT (1) ATE89730T1 (es)
CA (1) CA2023349A1 (es)
DE (2) DE3927113C2 (es)
DK (1) DK0413171T3 (es)
ES (1) ES2042153T3 (es)
FI (1) FI904092A0 (es)
NO (1) NO903608L (es)
YU (1) YU149290A (es)
ZA (1) ZA906486B (es)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9121204D0 (en) * 1991-10-04 1991-11-20 Euro Celtique Sa Medicament
GB2260081B (en) * 1991-10-04 1995-11-29 Euro Celtique Sa Use of ibuprofen/codeine mixtures in treatment of chronic pain
GB2281697A (en) * 1993-09-14 1995-03-15 Euro Celtique Sa Laxative compositions in capsules
GB2290965A (en) * 1994-07-11 1996-01-17 Therapicon Srl Multiple layer capsules for drugs
US5468502A (en) * 1994-12-20 1995-11-21 American Home Products Corporation Ibuprofen enhancing solvent system
US5641512A (en) * 1995-03-29 1997-06-24 The Procter & Gamble Company Soft gelatin capsule compositions
DE19545043A1 (de) * 1995-12-02 1997-06-05 Scherer Gmbh R P Pharmazeutische Präparate zur oralen Anwendung und Verfahren zu ihrer Herstellung
RS49982B (sr) 1997-09-17 2008-09-29 Euro-Celtique S.A., Sinergistička analgetička kombinacija analgetičkog opijata i inhibitora ciklooksigenaze-2
AU9587198A (en) * 1997-10-07 1999-04-27 Fuisz Technologies Ltd. Immediate release drug delivery forms
US6013280A (en) * 1997-10-07 2000-01-11 Fuisz Technologies Ltd. Immediate release dosage forms containing microspheres
US6608073B1 (en) 1998-10-14 2003-08-19 New Millennium Pharmaceutical Research, Inc. Intranasal codeine for the rapid suppression of cough and rapid relief of pain
AUPR549901A0 (en) 2001-06-06 2001-07-12 Vital Health Sciences Pty Ltd Topical formulation containing tocopheryl phosphates
DE60140141D1 (de) * 2000-11-14 2009-11-19 Vital Health Sciences Pty Ltd Zusammensetzungen umfassend Komplexe von Tocopherolphosphatderivaten
US20020177626A1 (en) * 2001-01-19 2002-11-28 Cook Graham D. Treatment of sleep disturbances
EP1420797A4 (en) * 2001-07-27 2005-03-02 Vital Health Sciences Pty Ltd DERMAL THERAPY USING PHOSPHATE DERIVATIVES OF ELECTRONIC TRANSFER AGENTS
DE60238276D1 (de) * 2001-12-13 2010-12-23 Vital Health Sciences Pty Ltd Transdermaler transport von verbindungen
AU2002950713A0 (en) * 2002-08-09 2002-09-12 Vital Health Sciences Pty Ltd Carrier
KR20050086954A (ko) * 2003-01-17 2005-08-30 바이탈 헬스 사이언시즈 피티와이 리미티드 항증식성 화합물
TWI367113B (en) 2003-02-12 2012-07-01 Syncera Inc Random and non-random alkylene oxide polymer alloy compositions
AU2003901815A0 (en) * 2003-04-15 2003-05-01 Vital Health Sciences Pty Ltd Phosphate derivatives
AU2003901813A0 (en) * 2003-04-15 2003-05-01 Vital Health Sciences Pty Ltd Pharmaceutical derivatives
WO2005084678A1 (en) * 2004-03-03 2005-09-15 Vital Health Sciences Pty Ltd Alkaloid formulations
US20060088590A1 (en) * 2004-10-22 2006-04-27 Banner Pharmacaps, Inc. Non-blooming gelatin and non-gelatin formulations
EP1858508A4 (en) * 2005-03-03 2009-01-07 Vital Health Sciences Pty Ltd COMPOUNDS HAVING ANTICANCER PROPERTIES
ES2557475T3 (es) * 2005-06-17 2016-01-26 Vital Health Sciences Pty Ltd. Un portador que comprende uno o más derivados di- y/o monofosfato de agentes de transferencia de electrones
US8852638B2 (en) 2005-09-30 2014-10-07 Durect Corporation Sustained release small molecule drug formulation
KR20080085839A (ko) * 2005-12-23 2008-09-24 바이탈 헬스 사이언시즈 피티와이 리미티드 사이토킨 조절 특성을 가진 화합물
CN101801415B (zh) 2007-05-25 2015-09-23 Rb医药品有限公司 利培酮化合物的持续递送制剂
US20100030576A1 (en) * 2008-07-30 2010-02-04 Mclane Advanced Technologies, Llc System and Method for Pain Management
WO2011094814A1 (en) 2010-02-05 2011-08-11 Phosphagenics Limited Carrier comprising non-neutralised tocopheryl phosphate
ES2829386T3 (es) 2010-03-30 2021-05-31 Phosphagenics Ltd Parche de administración transdérmica
GB2513060B (en) 2010-06-08 2015-01-07 Rb Pharmaceuticals Ltd Microparticle buprenorphine suspension
US9272044B2 (en) 2010-06-08 2016-03-01 Indivior Uk Limited Injectable flowable composition buprenorphine
EP2685992A4 (en) 2011-03-15 2014-09-10 Phosphagenics Ltd AMINO-QUINOLINES AS KINASE INHIBITORS
GB201404139D0 (en) 2014-03-10 2014-04-23 Rb Pharmaceuticals Ltd Sustained release buprenorphine solution formulations
US10973761B2 (en) 2015-12-09 2021-04-13 Phosphagenics Limited Pharmaceutical formulation
CN110662733A (zh) 2016-12-21 2020-01-07 埃维科生物技术有限公司 方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4552899A (en) * 1984-04-09 1985-11-12 Analgesic Associates Cough/cold mixtures comprising non-steroidal anti-inflammatory drugs
US4894234A (en) * 1984-10-05 1990-01-16 Sharma Shri C Novel drug delivery system for antiarrhythmics
DE3437599C2 (de) * 1984-10-13 1987-04-16 Dolorgiet GmbH & Co KG, 5205 St Augustin Ibuprofen enthaltende Weichgelatinekapseln
US4571400A (en) * 1984-12-18 1986-02-18 Belleview Pharmaceutical, Inc. Dihydrocodeine/ibuprofen pharmaceutical compositions and method
US4923898A (en) * 1984-12-26 1990-05-08 Analgesic Associates Analgesic, anti-inflammatory and skeletal muscle relaxant compositions comprising non-steroidal anti-inflammatory drugs and musculoskeletal relaxants and methods of using same
GB8521350D0 (en) * 1985-08-28 1985-10-02 Euro Celtique Sa Analgesic composition
GB8629567D0 (en) * 1986-12-10 1987-01-21 Boots Co Plc Therapeutic agents

Also Published As

Publication number Publication date
DE3927113C2 (de) 1993-11-25
DE3927113A1 (de) 1991-02-21
YU149290A (sh) 1992-12-21
NO903608D0 (no) 1990-08-16
EP0413171B1 (de) 1993-05-26
EP0413171A1 (de) 1991-02-20
CA2023349A1 (en) 1991-02-18
ATE89730T1 (de) 1993-06-15
US5173304A (en) 1992-12-22
DE59001544D1 (de) 1993-07-01
DK0413171T3 (da) 1993-10-04
FI904092A0 (fi) 1990-08-17
JPH03169809A (ja) 1991-07-23
ZA906486B (en) 1991-06-26
NO903608L (no) 1991-02-18

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