ES2040181A1 - Procedimiento para la obtencion de nuevas dihidropiridinas. - Google Patents

Procedimiento para la obtencion de nuevas dihidropiridinas.

Info

Publication number
ES2040181A1
ES2040181A1 ES929200754A ES9200754A ES2040181A1 ES 2040181 A1 ES2040181 A1 ES 2040181A1 ES 929200754 A ES929200754 A ES 929200754A ES 9200754 A ES9200754 A ES 9200754A ES 2040181 A1 ES2040181 A1 ES 2040181A1
Authority
ES
Spain
Prior art keywords
alkyl
substd
opt
phenyl
prepn
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES929200754A
Other languages
English (en)
Other versions
ES2040181B1 (es
Inventor
Javier Bertroli
Jordi Belloc
Elena Carceller
Carmen Almansa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Noucor Health SA
Original Assignee
J Uriach y Cia SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by J Uriach y Cia SA filed Critical J Uriach y Cia SA
Priority to ES9200754A priority Critical patent/ES2040181B1/es
Publication of ES2040181A1 publication Critical patent/ES2040181A1/es
Application granted granted Critical
Publication of ES2040181B1 publication Critical patent/ES2040181B1/es
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Landscapes

  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Procedimiento para la obtención de nuevas dihidropiridinas de fórmula I, donde X es N ó CH;R1 representa C1C4 alquilo o bencilo; R2 es H ó C1C4 alquilo; R3 representa 1H1,2,4 triazolilo, SO2Me, NHCOR4,NHCO2R4 ó NR5SO2R4, en donde R4 es C1C4 alquilo, C1C4 haloalquilo, fenilo opcionalmente sustituido, o un heterociclo de 5 ó 6 átomos de los cuales de 1 a 3 son nitrógeno y/o oxígeno y/o azufre, pudiendo estar dicho heterociclo opcionalmente sustituido, y R; es hidrógeno, C1C4 alquilo, fenil C1C4 alquilo, o fenilo opcionalmente sustituido; y Ar es un grupo fenilo opcionalmente sustituido por uno o varios grupos halógeno o trifluorometilo; caracterizado porque se hace reaccionar un compuesto de fórmula II con cloruro de nicotinilo para dar un compuesto de fórmula III, el cual se hace reaccionar con un agente alquilante R1Y (siendo Y un grupo saliente) y finalmente se reduce la sal de nicotinio formada.
ES9200754A 1992-03-30 1992-03-30 Procedimiento para la obtencion de nuevas dihidropiridinas. Expired - Fee Related ES2040181B1 (es)

Priority Applications (1)

Application Number Priority Date Filing Date Title
ES9200754A ES2040181B1 (es) 1992-03-30 1992-03-30 Procedimiento para la obtencion de nuevas dihidropiridinas.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES9200754A ES2040181B1 (es) 1992-03-30 1992-03-30 Procedimiento para la obtencion de nuevas dihidropiridinas.

Publications (2)

Publication Number Publication Date
ES2040181A1 true ES2040181A1 (es) 1993-10-01
ES2040181B1 ES2040181B1 (es) 1994-05-16

Family

ID=8276666

Family Applications (1)

Application Number Title Priority Date Filing Date
ES9200754A Expired - Fee Related ES2040181B1 (es) 1992-03-30 1992-03-30 Procedimiento para la obtencion de nuevas dihidropiridinas.

Country Status (1)

Country Link
ES (1) ES2040181B1 (es)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1646284A4 (en) * 2003-07-18 2008-09-24 Rhode Island Education AZOL DERIVATIVES AND METHOD FOR THEIR PREPARATION

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0078594A1 (en) * 1981-08-19 1983-05-11 Imperial Chemical Industries Plc Triazole derivatives, processes for preparing them, compositions containing them and processes for combating fungi and regulating plant growth
US4404216A (en) * 1981-06-06 1983-09-13 Pfizer Inc. Antifungal 1,3-bis-triazolyl-2-propanol derivative
EP0095828A1 (en) * 1982-04-01 1983-12-07 Pfizer Limited Antifungal triazolyl propanol derivatives
EP0178533A1 (en) * 1984-10-02 1986-04-23 Sumitomo Pharmaceuticals Company, Limited N-substituted triazole derivatives, and their production and use
EP0313782A2 (de) * 1987-09-25 1989-05-03 Bayer Ag Antimykotische Mittel

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4404216A (en) * 1981-06-06 1983-09-13 Pfizer Inc. Antifungal 1,3-bis-triazolyl-2-propanol derivative
EP0078594A1 (en) * 1981-08-19 1983-05-11 Imperial Chemical Industries Plc Triazole derivatives, processes for preparing them, compositions containing them and processes for combating fungi and regulating plant growth
EP0095828A1 (en) * 1982-04-01 1983-12-07 Pfizer Limited Antifungal triazolyl propanol derivatives
EP0178533A1 (en) * 1984-10-02 1986-04-23 Sumitomo Pharmaceuticals Company, Limited N-substituted triazole derivatives, and their production and use
EP0313782A2 (de) * 1987-09-25 1989-05-03 Bayer Ag Antimykotische Mittel

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1646284A4 (en) * 2003-07-18 2008-09-24 Rhode Island Education AZOL DERIVATIVES AND METHOD FOR THEIR PREPARATION

Also Published As

Publication number Publication date
ES2040181B1 (es) 1994-05-16

Similar Documents

Publication Publication Date Title
MY105494A (en) Triazole antifungal agents.
MY105092A (en) Triazole antifungal agents.
TW349843B (en) Substituted 1-arylpyrazoles
IL111245A0 (en) Cyclic amides and fungicidal compositions containing them
JPS5699465A (en) 33isothiazolone compound
ATE178894T1 (de) Herbizide 2,6-substituierte pyridine
ES8801654A1 (es) Un procedimiento para preparar derivados de piridina
SG49607A1 (en) 1-methylcarbapenem derivatives and process for preparation thereof
GR3003776T3 (es)
ES8702378A1 (es) Un derivado de triazol n-sustituido
ES2040181A1 (es) Procedimiento para la obtencion de nuevas dihidropiridinas.
AU575400B2 (en) Piperidine and imidazole and amino salt derivatives as plant growth regulators
ES8507515A1 (es) Un procedimiento para la preparacion de nuevos derivados de triazol dotados de accion antifungica
PL289726A1 (en) Herbicide
TW350757B (en) Benzisoxazole derivatives and pesticidal compositions containing them
MY109714A (en) Process for preparing 8-chloroquinolone derivatives
ATE35539T1 (de) Verbindungen mit fungizider wirkung.
TW325463B (en) 4-Aminobenzoylguanidine-derivatives
EP0298752A3 (en) Mercapto-substituted pyridine compounds and process for preparing the same
CA2056334A1 (en) Process for producing benzylphthalazinone derivatives and salts thereof
MY106503A (en) Imidazolidine derivatives, process for producing the same and pesticides containing the same
EP0623622A4 (en) METHOD FOR PRODUCING CEPHEMIC COMPOUNDS.
GB1374964A (en) Hexahydrotriazinone derivatives and herbicidal compositions containing them
ES8700244A1 (es) Un procedimiento para la preparacion de nuevos derivados de triazol
JPS5740466A (en) Aminoethyl-substituted pyrazole derivative and its preparation

Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20000301